Hydroxyl Groups Of Glycerol Research Articles

On the kinetics of multiphase etherification of glycerol with isobutene

The etherification of the hydroxyl groups of glycerol with isobutene successively forms mono-ethers (ME), di-ethers (DE) and tri-ether (TE) of glycerol, which are desired fuel additives. The initial rates of each step in the consecutive etherification were measured independently under various concentrations and temperatures. The initial rate of ME synthesis from glycerol and isobutene was independent of the initial composition due to the invariant concentrations of reactants in the reaction phase. Adding ME to the glycerol-isobutene reaction was observed to accelerate the glycerol conversion by enhancing the solvation of isobutene in glycerol. Rate expressions in the form of power-law with parameters regressed from initial rates measured separately for each etherification step were found to be unable to predict the kinetics of complex reaction where all reaction steps coexisted together. This signifies significant interaction of reactions and competitive adsorption of reactants. Glycerol etherification with isobutene under high conversions where all reactions and reactants exist simultaneously was carried out to obtain kinetic data containing the interactions between different reactions. Thereafter a model considering phase separation and competitive adsorption was proposed and correlated with the initial rates and kinetic data under high conversions. The model was capable to describe all observed kinetics.

Thermoreversible cross-linking of maleated natural rubber with glycerol

In this article, thermoreversible covalent cross-linking of maleated natural rubber (MNR) with glycerol was studied. Firstly, NR was grafted with maleic anhydride using a reactive processing method. The result showed that MNR was successfully obtained without the addition of initiator. The highest grafting was 1.76%. Secondly, the obtained MNR was dissolved in toluene and then mixed with glycerol, which is used in this study as the thermoreversible cross-linking agent. Fourier transform infrared spectra of the casted MNR film mixed with glycerol showed that upon heating, covalent ester cross-links were formed via the reaction of succinic anhydride ring with hydroxyl groups of glycerol. The swelling test indicated that the swelling index (%) decreased with increasing glycerol loading. This indicated that the degree of cross-linking directly depended on the amount of glycerol. The tensile strength and modulus were significantly improved upon increasing the level of cross-linking. The MNR cross-linked with glycerol can be remolded at 150°C more than three times. After remolding, the mechanical properties decreased with increasing recycling round.

Synthesis and Thermal Properties of Poly(ethylene glycol)-polydimetylsiloxane Crosslinked Copolymers

Poly(ethylene glycol)-polydimethylsiloxane (PEG-PDMS) crosslinked copolymers with mol ratios PEG:PDMS:Glycerol of 5:3:2, 6:2:2 and 7:1:2 have been prepared and characterized. The synthesis of the copolymers was carried out by the reaction between hydroxyl groups of PEG, PDMS and glycerol with isocyanate groups of 1,6-hexamethyelene diisocyanate (HMDI). In the reaction, glycerol was acted as the cross linker. The copolymers were then characterized by FTIR spectroscopy. The thermal behaviour was investigated by DSC and TGA. Based on FTIR results, the crosslinked structure of the copolymers was confirmed by the presence of absorption peak at 3350 and 1710 cm-1 which indicated the (-N-H) stretching and carbonyl (-C=O) correspond to urethane links. This showed that the hydroxyl groups of PEG, PDMS and glycerol have reacted to isocyanate groups of HMDI. The copolymers showed melting temperature (Tm) of PEG segments from 22°C to 27°C and glass transition temperature (Tg) from -11°C to -6°C. Meanwhile, the PDMS segment showed values from -53°C to -56°C for Tm, and Tg from -118°C to -122°C. Data obtained from the thermal analysis indicate that thermal stability increases with increasing PDMS mol ratio.

Modification of ɛ‐poly‐L‐lysine in vivo to reduce self‐toxicity and enhance antibiotic overproduction

ɛ‐poly‐L‐lysine (ɛ‐PL) is a novel commercial food preservative, and glucose and glycerol are two carbon sources commonly used in ɛ‐PL fermentation. Using MALDI‐TOF and NMR, when grown in glycerol‐based medium, but not glucose‐based medium is determined, Streptomyces albulus J1‐005 produces a derivative of ɛ‐PL in which the terminal carboxyl group is modified with the second hydroxyl group of glycerol. Interestingly, this derivative, 2‐ɛ‐poly(L‐lys)‐glycerol, was hydrolyzed back to ɛ‐PL when the pH was adjusted from 3.7 to the neutral range. Antimicrobial assays indicated that, compared to ɛ‐PL, 2‐ɛ‐poly(L‐lys)‐glycerol has similar inhibitory activity against several bacterial species but is less inhibitory to the producing strain. Additionally, in fed‐batch fermentation, product yield was 37% higher in glycerol‐based medium than in medium containing an equal amount of glucose. Hence, we propose that such culture‐based approaches for modifying toxic compounds in vivo can be a promising strategy for antibiotic overproduction. © 2018 American Institute of Chemical Engineers AIChE J, 64: 4187–4192, 2018

Transition metal-promoted hierarchical ETS-10 solid base for glycerol transesterification.

A transesterification reaction has been carried out over a transition metal modified hierarchical ETS-10 (METS-10) catalyst to synthesize glycerol carbonate (GC) from glycerol. The inherent Lewis basicity of ETS-10 favors oriented conversion of glycerol, and the hierarchical structure benefits exposure of more active sites, shortens the molecular diffusion path, suppresses the formation of coke in the micropores, and then enhances the catalytic reactivity and stability. Furthermore, the influence of transition metals (Fe, Co, Ni, Cu, Zn and Mn) on the basic sites of supports has been investigated in detail. It is found that basicity change of the catalyst depends on not only the cation size, nature and composition of the transition metal but also the zeolite structure and pore topology. Besides, the presence of a certain amount of Ni0 species from catalyst reduction has proved to play a critical role in strengthening the interaction of Lewis basic sites (TiO62−) with active glycerol hydroxyl groups. Finally, a 97.7% glycerol conversion and 97.1% GC yield have been obtained over Ni/METS-10, of which the high catalytic performance can be maintained after 8 runs.

Lateral cross-linking of polyurethane using isophorone diisocyanate and glycerol to control tensile and shape memory properties

Lateral cross-linking of polyurethane (PU) was used in this study to improve the tensile strength, thermal stability, and shape memory effect of PU. The hard segment in the middle of PU was used as the cross-linking site to attain high tensile stress and reproducible shape recovery without a significant decrease in tensile strain. Specifically, we investigated whether lateral cross-linking of PU using isophorone diisocyanate (IPDI) is feasible by linking the carbamate bonding or glycerol hydroxyl groups of PU. Therefore, the effects of the IPDI cross-linking site and the cross-linker content were examined by comparing the thermal, tensile, and shape memory properties as well as the cross-link density and water swelling with those of unmodified PU.

Promoting role of bismuth and antimony on Pt catalysts for the selective oxidation of glycerol to dihydroxyacetone

The group 15 metals, bismuth and antimony, play important roles in promoting noble-metal-catalyzed oxidation reactions toward high value-added chemicals. Herein, we report that the selective oxidation of glycerol to 1,3-dihydroxyacetone (DHA) catalyzed by Pt supported on N-doped carbon nanotubes (Pt/NCNT) can be significantly promoted in the presence of Bi or Sb in reaction solution. This catalyst system showed not only comparable even better performance to the Pt/NCNT with pre-loaded Bi, but also the greatly simplified catalyst preparation. It was found that the Bi-promoted Pt/NCNT underwent dynamic surface reconstruction through leaching and adsorption of Bi adatoms, due to the formation of glyceric acid. By characterizing the adsorption of Bi on Pt catalyst with high-resolution transmission electron microscopy, CO-stripping, horizontal attenuated total reflection infrared spectroscopy and X-ray photoelectron spectroscopy, it has been ascertained that Bi preferentially deposits on the step sites of Pt, and then blocks the terrace sites to promote the Pt catalyst mainly through a geometrical effect, which facilitates the activation and transformation of the secondary hydroxyl group of glycerol through the chelation between substrate and Pt–Bi sites.

Ester Cross-Link Profiling of the Cutin Polymer of Wild-Type and Cutin Synthase Tomato Mutants Highlights Different Mechanisms of Polymerization.

Cuticle function is closely related to the structure of the cutin polymer. However, the structure and formation of this hydrophobic polyester of glycerol and hydroxy/epoxy fatty acids has not been fully resolved. An apoplastic GDSL-lipase known as CUTIN SYNTHASE1 (CUS1) is required for cutin deposition in tomato (Solanum lycopersicum) fruit exocarp. In vitro, CUS1 catalyzes the self-transesterification of 2-monoacylglycerol of 9(10),16-dihydroxyhexadecanoic acid, the major tomato cutin monomer. This reaction releases glycerol and leads to the formation of oligomers with the secondary hydroxyl group remaining nonesterified. To check this mechanism in planta, a benzyl etherification of nonesterified hydroxyl groups of glycerol and hydroxy fatty acids was performed within cutin. Remarkably, in addition to a significant decrease in cutin deposition, mid-chain hydroxyl esterification of the dihydroxyhexadecanoic acid was affected in tomato RNA interference and ethyl methanesulfonate-cus1 mutants. Furthermore, in these mutants, the esterification of both sn-1,3 and sn-2 positions of glycerol was impacted, and their cutin contained a higher molar glycerol-to-dihydroxyhexadecanoic acid ratio. Therefore, in planta, CUS1 can catalyze the esterification of both primary and secondary alcohol groups of cutin monomers, and another enzymatic or nonenzymatic mechanism of polymerization may coexist with CUS1-catalyzed polymerization. This mechanism is poorly efficient with secondary alcohol groups and produces polyesters with lower molecular size. Confocal Raman imaging of benzyl etherified cutins showed that the polymerization is heterogenous at the fruit surface. Finally, by comparing tomato mutants either affected or not in cutin polymerization, we concluded that the level of cutin cross-linking had no significant impact on water permeance.

Base-free aerobic oxidation of glycerol on TiO2-supported bimetallic Au–Pt catalysts

The aerobic oxidation of glycerol provides an economically viable route to glyceraldehyde, dihydroxyacetone and glyceric acid with versatile applications, for which monometallic Pt, Au and Pd and bimetallic Au–Pt, Au–Pd and Pt–Pd catalysts on TiO2 were examined under base-free conditions. Pt exhibited a superior activity relative to Pd, and Au–Pd and Pt–Pd while Au was essentially inactive. The presence of Au on the Au–Pt/TiO2 catalysts led to their higher activities (normalized per Pt atom) in a wide range of Au/Pt atomic ratios (i.e. 1/3–7/1), and the one with the Au/Pt ratio of 3/1 exhibited the highest activity. Such promoting effect is ascribed to the increased electron density on Pt via the electron transfer from Au to Pt, as characterized by the temperature-programmed desorption of CO and infra-red spectroscopy for CO adsorption. Meanwhile, the presence of Au on Au–Pt/TiO2, most like due to the observed electron transfer, changed the product selectivity, and facilitated the oxidation of the secondary hydroxyl groups in glycerol, leading to the favorable formation of dihydroxyacetone over glyceraldehyde and glyceric acid that were derived from the oxidation of the primary hydroxyl groups. The synergetic effect between Au and Pt demonstrates the feasibility in the efficient oxidation of glycerol to the targeted products, for example, by rational tuning of the electronic properties of metal catalysts.

In vitro reduced availability of aflatoxin B1 and acrylamide by bonding interactions with teichoic acids from lactobacillus strains

Several studies have evidenced the ability of some lactic acid bacteria to bind dietary carcinoges, including aflatoxin B1 (AFB1) and acrylamide (AA). Cell wall teichoic acids (TAs) appear to be components of the bacterial that might participate in binding; however, the exact mechanisms are not clear. The aims of this work were to assess the ability of fourteen Lactobacillus strains to bind either AFB1 or AA, and to determine the possible molecular bonding interactions among toxins and constituents of TAs. Physical binding was assessed in aqueous solution, and the compontents of TAs were determined by evaluation of hydrolysis products of TAs. Binding was strain- and toxin-specific dependent. All AFB1-bacterium interactions were partly reversible, while AA-bacterium appeared to be irreversible. TAs from the evaluated strains consisted of poly(ribitol phosphate) polymers decorated with glucose, d-alanine and/or glycerol molecules, thus four simplified structures were proposed. Based on compositional analysis it was hypothesized that hydroxyl groups of AFB1 as well as carbonyl oxygens of both AFB1 and AA, might be involved in interactions between both toxins and the hydroxyl groups of either glucose or glycerol in TAs. The results of this work support the suggestion that specific Lactobacillus strains can reduce the bioavailability of dietary carcinogens, and provide for the first time new insights on teichoic acid structure relationships on toxin binding ability.

Structural and mechanical properties of cardiolipin lipid bilayers determined using neutron spin echo, small angle neutron and X-ray scattering, and molecular dynamics simulations.

The detailed structural and mechanical properties of a tetraoleoyl cardiolipin (TOCL) bilayer were determined using neutron spin echo (NSE) spectroscopy, small angle neutron and X-ray scattering (SANS and SAXS, respectively), and molecular dynamics (MD) simulations. We used MD simulations to develop a scattering density profile (SDP) model, which was then utilized to jointly refine SANS and SAXS data. In addition to commonly reported lipid bilayer structural parameters, component distributions were obtained, including the volume probability, electron density and neutron scattering length density. Of note, the distance between electron density maxima DHH (39.4 Å) and the hydrocarbon chain thickness 2DC (29.1 Å) of TOCL bilayers were both found to be larger than the corresponding values for dioleoyl phosphatidylcholine (DOPC) bilayers. Conversely, TOCL bilayers have a smaller overall bilayer thickness DB (36.7 Å), primarily due to their smaller headgroup volume per phosphate. SDP analysis yielded a lipid area of 129.8 Å(2), indicating that the cross-sectional area per oleoyl chain in TOCL bilayers (i.e., 32.5 Å(2)) is smaller than that for DOPC bilayers. Multiple sets of MD simulations were performed with the lipid area constrained at different values. The calculated surface tension versus lipid area resulted in a lateral area compressibility modulus KA of 342 mN m(-1), which is slightly larger compared to DOPC bilayers. Model free comparison to experimental scattering data revealed the best simulated TOCL bilayer from which detailed molecular interactions were determined. Specifically, Na(+) cations were found to interact most strongly with the glycerol hydroxyl linkage, followed by the phosphate and backbone carbonyl oxygens. Inter- and intra-lipid interactions were facilitated by hydrogen bonding between the glycerol hydroxyl and phosphate oxygen, but not with the backbone carbonyl. Finally, analysis of the intermediate scattering functions from NSE spectroscopy measurements of TOCL bilayers yielded a bending modulus KC of 1.06 × 10(-19) J, which was larger than that observed in DOPC bilayers. Our results show the physicochemical properties of cardiolin bilayers that may be important in explaining their functionality in the inner mitochondrial membrane.

Thermogravimetric investigation of sol–gel microspheres doped with aqueous glycerol

Abstract Background Silica-based microspheres encapsulating aqueous glycerol are promising curing agents affording the formation of better one-component polyurethane foams, namely thermoset polymers cured by atmospheric moisture that are widely and increasingly utilized in the construction industry. The use of renewable, non toxic glycerol from biodiesel and oleochemicals industry to cure PU foams in place of traditionally employed oil-derived mono and diethylene glycols is both technically and environmentally beneficial. The higher amount of hydroxyl groups in glycerol compared to both mono- and diethylene glycol results in considerably lower percentage of free monomeric methylene diphenyl diisocyanate (MDI) and higher crosslinking density of the cured foam. Results We investigate by thermogravimetric analysis the nature and amount of the microencapsulated species in sol–gel silica and organosilica microspheres encapsulating aqueous glycerol. Along with a percentage of glycerol in weight up to 35%, the microspheres contain about 5 wt% water and 4 wt% entrapped surfactant. Conclusions The investigation shows the efficacy of the surfactant-assisted sol–gel microencapsulation aqueous glycerol in silica as well as in methyl-silica particles at least until 10% degree of methylation. The results are relevant to the practical development of functional materials that can be used to cure better and greener polyurethane foams largely employed as coatings, adhesives and sealants in many industrial sectors.

Polymerization effect of electrolytes on hydrogen-bonding cryoprotectants: ion-dipole interactions between metal ions and glycerol.

Protectants which are cell membrane permeable, such as glycerol, have been used effectively in the cryopreservation field for a number of decades, for both slow cooling and vitrification applications. In the latter case, the glass transition temperature (Tg) of the vitrification composition is key to its application, dictating the ultimate storage conditions. It has been observed that the addition of some electrolytes to glycerol, such as MgCl2, could elevate the Tg of the mixture, thus potentially providing more storage condition flexibility. The microscopic mechanisms that give rise to the Tg-enhancing behavior of these electrolytes are not yet well understood. The current study focuses on molecular dynamics simulation of glycerol mixed with a variety of metal chlorides (i.e., NaCl, KCl, MgCl2, and CaCl2), covering a temperature range that spans both the liquid and glassy states. The characteristics of the ion–dipole interactions between metal cations and hydroxyl groups of glycerol were analyzed. The interruption of the original hydrogen-bonding network among glycerol molecules by the addition of ions was also investigated in the context of hydrogen-bonding quantity and lifetime. Divalent metal cations were found to significantly increase the Tg by strengthening the interacting network in the electrolyte/glycerol mixture via strong cation–dipole attractions. In contrast, monovalent cations increased the Tg insignificantly, as the cation–dipole attraction was only slightly stronger than the original hydrogen-bonding network among glycerol molecules. The precursor of crystallization of NaCl and KCl was also observed in these compositions, potentially contributing to weak Tg-enhancing ability. The Tg-enhancing mechanisms elucidated in this study suggest a structure-enhancing role for divalent ions that could be of benefit in the design of protective formulations for biopreservation purposes.

Synthesis of glycerol carbonate from the transesterification of dimethyl carbonate with glycerol using DABCO and DABCO-anchored Merrifield resin

Both DABCO (1,4-diazabicyclo[2.2.2]octane) and Merrifield resin-anchored DABCO ([p-DABCO]Cl), prepared from the reaction of DABCO and Merrifield resin, were found to exhibit high activities for the transesterification of dimethyl carbonate (DMC) with glycerol to produce glycerol carbonate (GLC). FT-IR and NMR spectroscopic results suggest that such a high transesterification activity of DABCO could be attributed to its superior ability to activate glycerol via a strong hydrogen bond formation between a hydroxyl group of glycerol and an amino group of DABCO. Meanwhile, the activation of glycerol by [p-DABCO]Cl proceeds mainly through the hydrogen bond interaction between a hydroxyl group or groups of glycerol and Cl− of [p-DABCO]Cl. The catalytic activity of [p-DABCO]Cl was maintained up to 5 reuses, demonstrating that [p-DABCO]Cl could be used as a recyclable heterogeneous catalyst.

Synthesis and Characterization of Nitrogen-Doped Carbon Nanospheres Decorated with Au Nanoparticles for the Liquid-Phase Oxidation of Glycerol

Carbon and nitrogen-doped carbon nanospheres (CNS) were prepared by thermal pyrolysis of benzene (CNSB), aniline (CNSAN), and nitrobenzene (CNSNB) and used as supports for gold nanoparticles. Gold-based catalysts were prepared by the gold-sol method. The catalysts were checked in liquid-phase glycerol oxidation. The nature of the N-containing groups influenced both the acid–base properties of the supports and the Au particle deposition. As a consequence, an enhanced metal sintering by enriching the surface electron density of the support, essentially in the quaternary form, was observed. Both the glycerol conversion and glyceric acid selectivity increased with decreasing gold particle size. Moreover, catalyst Au/CNSB promoted the formation of glyceric acid, whereas Au/CNSAN and Au/CNSNB catalysts favored the oxidation of the secondary hydroxyl group of glycerol. Results clearly confirmed the influence of the support properties on the catalytic performance of gold in selective glycerol oxidation.

Cross-linking xanthan and other compounds with glycerol

In a waterless or near-waterless environment glycerol's hydroxyl groups react with xanthan's functional groups to make glycerol cross-linked xanthan (GCX) since not enough water is present to inhibit glycerol-xanthan reactions. The water, formed during cross-linking, in fact catalyzes the unwinding of xanthan's double-helix thus making functional groups of its side chains and of its backbone more accessible for cross-linking. Functional groups of xanthan's side chains and those in its backbone are cross-linked with glycerol monomers and oligomers. Glycerol monomers and its oligomers cross-link xanthan when glycerol to xanthan weight ratio is smaller than 27.6. Hardness increases with an increase of xanthan to glycerol ratio; GCX made with 50% wt xanthan is a hard solid material almost 40 times harder than GCX gel made with 5% wt xanthan. A gram of GCX absorbs more than 39 g of water. In a waterless or near-waterless environment glycerol cross-links xanthan and other bio-polymers. Materials made by glycerol cross-linking of bio-polymers can be used as hydrogels, absorbents, coatings, carriers in controlled delivery of chemicals, films, membranes and are of interest for those and other applications in agriculture, food, pharmaceutical and other industries. Using glycerol to cross-link bio-polymers and other compounds will also help decrease the pressure on the water resources and minimize pollution of the environment.

Phosphatidic acid in neuronal development: a node for membrane and cytoskeleton rearrangements.

Phosphatidic acid (PA) is the simplest phospholipid naturally existing in all-living organisms. It constitutes only a minor fraction of the total cell lipids but has attracted considerable attention being both a lipid second messenger and a modulator of membrane shape. The pleiotropic functions of PA are the direct consequence of its very simple chemical structure consisting of only two acyl chains linked by ester bonds to two adjacent hydroxyl groups of glycerol, whose remaining hydroxyl group is esterified with a phosphomonoester group. Hence the small phosphate head group of PA gives it the shape of a cone providing flexibility and negative curvatures in the context of a lipid bilayer. In addition, the negatively charged phosphomonoester headgroup of PA is unique because it can potentially carry one or two negative charges playing a role in the recruitment of positively charged molecules to biomembranes. In consequence, PA has been proposed to play various key cellular functions. In the brain, a fine balance between cell growth, migration and differentiation, and cell death is required to sculpt the nervous system during development. In this review, we will summarize the various functions that have been proposed for PA in neuronal development.

Effect of Zn doping on the hydrogenolysis of glycerol over ZnNiAl catalyst

Nickel based catalyst is of interest in the industrial catalytic processes, and it is always modified by doping a second element to improve its catalytic properties. Understanding the role of dopant is extremely helpful in tailoring the active centers. In this work, Zn could induce a significant improvement of the catalytic performance of NiAl for the hydrogenolysis of glycerol. The Zn doped ZnNiAl catalysts exhibited high activity and the improved selectivity to 1,2-propanediol, it was about 2 times higher than the original ones. The ZnNi alloy formed in ZnNiAl was responsible for the noticeable catalytic performance. They preferred to coordinate with the end hydroxyl group of glycerol, promoted the cleavage of CO bond in glycerol, and resulted in the dominant formation of 1,2-propanediol. The findings described here will provide a useful knowledge for rational design of nickel-based catalysts, as well as reveal a new reaction model for the hydrogenolysis of glycerol.

Glycerol Adsorption on Platinum Surfaces: A Density Functional Theory Investigation with van der Waals Corrections

Glycerol has been suggested as an additional energy source for hydrogen production for fuel cell applications, and several experimental studies have been reported on glycerol conversion on transition-metal surfaces; however, our atomistic understanding of glycerol–metal interactions is still far from satisfactory. In this work, we will report a theoretical investigation of the adsorption properties of glycerol on the Pt(110), Pt(100), and Pt(111) surfaces based on density functional theory (DFT) calculations with van der Waals (vdW) corrections to the DFT total energy. In the lowest energy configurations, which differ by millielectron volts, glycerol is almost parallel to the Pt surfaces and interacts with the Pt surfaces via one of the hydroxyl groups near the on-top Pt sites, which strongly affects the orientation of glycerol relative to the surface. Our results and analyses indicate that the adsorbate structure is among the high energy configurations of glycerol in gas phase. The vdW correction enhances the adsorption energy and hence decreases the equilibrium glycerol–metal distance; in particular, it affects mainly the adsorbate structure for glycerol on Pt(110), leading to the binding of two edge glycerol hydroxyl groups to the Pt(110) surface. Moreover, the vdW correction enhances the magnitude of the glycerol adsorption energy more on Pt(111) and less on Pt(110) surfaces; however, without changing the relative order of the adsorption energies, that is, glycerol binds more strongly on Pt(110) and more weakly on Pt(111) surface. We found large work function changes (0.7–1.0 eV) upon glycerol adsorption and negligible changes in the Bader charges of the H, C, O, and Pt atoms, and hence, polarization effects play a crucial role in the interaction mechanism.

Measurements and modeling of CO2 solubility in 1,8-diazabicyclo-[5.4.0]-undec-7-ene—Glycerol solutions

The solubility of CO2 in pure 1,8-diazabicyclo-[5.4.0]-undec-7-ene (DBU) and pure glycerol were determined with the static total pressure method. Additionally, a switchable ionic liquid was formed by dissolving CO2 into DBU–glycerol mixtures. All measurements were conducted at temperatures from 302 to 353K. In addition, density of DBU was measured at temperatures from 293 to 358K.The solubility of CO2 into DBU–glycerol solutions was slightly temperature dependent at the measured temperature range. CO2 solubility was found to depend strongly on the composition of DBU–glycerol solution and the partial pressure of CO2. Highest loadings to DBU were achieved with glycerol rich mixtures. A model taking into account the effect of DBU:glycerol ratio was developed. A CO2 molecule bound to the glycerol hydroxyl group was assumed to hinder reactivity of the remaining hydroxyl groups in the glycerol molecule, therefore affecting CO2 solubility in the solution. In the model, the equilibrium reactions between CO2, DBU and the hydroxyl groups of glycerol were simplified to two reactions. In addition, the physical solubility of CO2 in pure DBU and glycerol was measured and modeled. The physical solubility model was used in modeling CO2 solubility in DBU–glycerol solutions.