Enhancing flood resilience has become crucial for watershed flood prevention. However, current methods for quantifying resilience often exhibit coarse spatiotemporal granularity, leading to insufficient precision in watershed resilience assessments and hindering the accurate implementation of resilience enhancement measures. This study proposes a watershed flood resilience assessment method based on a system performance curve that considers thresholds of inundation depth and duration. A nested one- and two-dimensional coupled hydrodynamic model, spanning two spatial scales, was utilized to simulate flood processes in plain river network areas with detailed and complex hydraulic connections. The proposed framework was applied to the Hangjiahu area (Taihu Basin, China). The results indicated that the overall trend of resilience curves across different underlying surfaces initially decreased and then increase, with a significant decline observed within 20–50 h. The resilience of paddy fields and forests was the highest, while that of drylands and grasslands was the lowest, but the former had less recovery ability than the latter. The resilience of urban systems sharply declined within the first 40 h and showed no signs of recovery, with the curve remaining at a low level. In some regions, the flood tolerance depth and duration for all land use types exceeded the upper threshold. The resilience of the western part of the Hangjiahu area was higher than that of other regions, whereas the resilience of the southern region was lower compared to the northern region. The terrain and tolerance thresholds of inundation depth were the main factors affecting watershed flood resilience. The findings of this study provide a basis for a deeper understanding of the spatiotemporal evolution patterns of flood resilience and for precisely guiding the implementation and management of flood resilience enhancement projects in the watershed.