The Non-Orthogonal Multiple Access (NOMA) and the Orthogonal Frequency Division Multiple Access (OFDMA) are promising techniques for next-generation wireless systems. Although much attention in the literature considered these techniques, an effective combination between such systems as hybrid multiple access (HMA) needs more attention. For this reason, this paper devotes to proposing two different scenarios of HMA using multi-user OFDM (MU-OFDM) and power domain (PD) NOMA for downlink transmission to overcome the limitations of both Orthogonal Multiple Access (OMA) and NOMA. Due to the randomness of a wireless channel, different user grouping strategies and dynamic power allocation (DPA) strategies are employed to satisfy users’ requirements. The proposed systems give high flexibility utilizing bitrate allocation and user fairness. System results show superior performance to traditional OMA and NOMA systems. The achieved variety of fairness is helpful for the diversity of applications which is a principal requirement for beyond-fifth-generation (B5G) networks. The next step in this analysis is to enhance the proposed systems’ spectral efficiency (SE) by introducing beamforming for massive Multiple-Input Multiple-Output (MIMO) systems. The bit error rate (BER) result of the proposed system achieves almost the same error floor with a benefit of approximately 10 dB signalto-noise ratio (SNR) when 90 resource blocks (RBs) are used.
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