The HydroGEN Energy Materials Network (EMN) supernode in low temperature electrolysis combines capabilities from the National Renewable Energy Laboratory (NREL), Lawrence Berkeley National Laboratory (LBNL), and Savannah River National Laboratory (SRNL) to perform relevant and ground-breaking research outside of EMN-funded projects. The low temperature electrolysis supernode focuses on: evaluating and bridging the gap between rotating disk electrode half-cell activity and membrane electrode assembly single-cell performance; and understanding how electrode composition and processing parameters affects device performance. Ex-situ testing has been used to screen a variety of catalysts and correlate oxygen evolution activity to in-situ performance. Gaps between half- and single-cells were attributed to differences in configuration and standardized test parameters. While non-kinetic loss in membrane electrode assemblies are primarily due to resistance (ohmic), significantly larger transport losses are found in rotating disk electrodes due to electrode orientation and agitation. Differences in kinetics between these methods is primarily due to temperature. Increasing half-cell temperature and using flow cells can be used to bridge the gap between ex- and in-situ performance. Various oxygen evolution catalyst types, including different surfaces (metal/oxide), supports, surface areas, and components, were evaluated to address test differences across these material sets. Additionally, electrode composition and processing parameters were evaluated for their affect in electrolysis performance. Although catalyst layer uniformity may not significantly affect device performance at high loading, coating methodology is critical at low loading. Various spray coating parameters, including ink composition (ionomer content, water/alcohol ratio), drying temperature, and deposition rate were evaluated and found to alter the resulting performance in membrane electrode assemblies. Ionomer content was further correlated to half-cell tests, where low content may adversely impact ink stability (catalyst layer uniformity) and the catalyst layer interface, while high content may lower performance through contaminant effects. Parameters from spray coating tests were applied to slot die and gravure coating methods to transfer this understanding to larger-scale processes. Efforts to tune coating parameters utilize rheology studies and ex-situ characterization to assess catalyst-ionomer-solvent interactions and ionomer thin films. Multiscale modelling was used to evaluate membrane electrode assembly performance and separate kinetic, transport, and ohmic losses. Composition and processing parameters were additionally applied to hybrid cycles.