Gender inequality and poor women empowerment retard improvement in living standards of women and act as a clog in their contributions to governance and economic development. Gender inequality lower quality of life and culminates in limited productivity, hinder economic efficiency and growth. For over three decades, gender issues have been at the front burner of international summits. In spite of much progress in recent times, gender inequalities remain pervasive in many dimensions of life in various regions around the world particularly in sub-Saharan Africa (SSA). Treatment of women is yet to be fairer and related policies can be more effective to improve the status of women. No-doubt studies have been carried out on gender inequality, but less emphasis has been raveled with respect to hindrances and implications of gender inequality. Hence, understanding the nature of gender inequality will not only promote sound awareness among African countries, but also ignite government efforts as well as NGOs toward effective interventions for reduction of gender inequality especially in the economic and political realms where women are made worse off by the socio-cultural milieu. The methodological approach to this paper was based on reviews of published multiple documents to draw up statistical profile of the situation of women in selected countries of low human Development index in SSA to show the existence of gender inequality. The paper found among all the 12 low human development countries and SSA region examined that gender indicators such as human development index, expected years of schooling, mean years of schooling, estimated gross national per capita, share of seats in parliament, population with at least secondary education and labor-force participation rate are all in favor of men. The paper concludes with recommendations to narrow the gender gaps.