Makassar Hospital Research Articles

Significance of HBsAg Expression in Placental Tissue with Serum Positivity in Hepatitis B Virus-infected Mother

Introduction: Hepatitis B virus infection in fetal and newborn may result from the intrauterine vertical transmission. The purpose of our study is to determine the association between HBsAg expression in the placental and HBsAg serum in pregnant women. Methods: Total 67 placental tissues and serum were obtained from HBV-infected mothers. This study was conducted in various hospitals in Makassar, Indonesia from December 2017 until August 2018. Maternal serum and placental tissues were tested by ELISA and Immunohistochemistry staining. Results: 67 samples from placental tissues and serum were categorized into two different levels of serum titer and staining positivity. Twenty nine samples (43.3%) were categorized in low titer of HBsAg positive serum and 38 samples (56.7%) in high titer of HBsAg positive serum. From the total of 67 placental samples, 43 (64.2%) samples had positive expression of HBsAg immunohistochemistry staining and 24 (34.8%) samples had negative expressions. Conclusions: There was a significant correlation between the expressions of HBsAg in the placental tissues and serum titers of HBV-infected mothers that is important in predicting the risk of transplacental transmission. The results of this study can be used as guidelines for the prevention and therapeutic approach of mother-to-child HBV infection.

Analysis of Nutritional Status, Body Composition, and Creatinine Levels in Hemodialysis Patients at Ibnu Sina Yw-Umi Hospital Makassar

Hemodialysis is an essential therapy for managing chronic kidney failure, helping to maintain homeostasis by removing excess fluids, solutes, and toxins from the body. The global increase in the prevalence of chronic kidney disease (CKD) has led to a rising demand for hemodialysis. This study aims to analyze the relationship between nutritional status, body composition, and creatinine levels in hemodialysis patients at Ibnu Sina YW-UMI Makassar Hospital. Using an observational cross-sectional design, the study involved 16 patients whose body mass index (BMI), muscle mass, fat mass, total body fluid, and visceral fat were measured before and after dialysis. The results revealed significant changes in nutritional status, body composition, and creatinine levels pre- and post-hemodialysis, analyzed through paired T-tests at a 0.05 confidence level. Most patients were male, aged over 45, with normal nutritional status but abnormal creatinine levels. Body composition analysis showed significant differences in muscle mass, fat mass, total body fluid, and visceral fat before and after hemodialysis, with patients with higher muscle mass tending to have elevated creatinine levels. This study emphasizes the importance of monitoring body composition and creatinine levels to support the health of hemodialysis patients and highlights the need for personalized nutritional and therapeutic interventions in CKD care. Further research is needed to explore the long-term impacts of hemodialysis on nutritional status and kidney function.

6-month survival of patients with acute myeloid leukemia who received modified chemotherapy at Wahidin Sudirohusodo Hospital

Background and aim. Standard chemotherapy for AML is daunorubicin combined with cytarabine. However, the combination chemotherapy also has side effects that are quite dangerous for AML patients. The purpose of this study is to assess the survival rates of AML patients treated at Wahidin Sudirohusodo Hospital in Makassar using modified chemotherapy regimens. Methods and material. This study was conducted at Wahidin Sudirohusodo Hospital in Makassar using a prospective cohort design. The study population included AML patients aged 18 years or older who had undergone modified chemotherapy for six months. Data on life expectancy, chemotherapy modifications, age, gender, and AML subtype were collected. Data were analyzed using SPSS version 22.0. Survival analysis was performed using the Kaplan-Meier curve, log-rank, and statistic test. Results. The cohort consisted of 25 males (51%) and 24 females (49%) with a mean age of 42 years. The 6-month survival rates were 68% for females and 50% for males. Age-based survival rates were 61.3% for patients <45 years, and 55.6 for those >45 years. Survival rates by AML subtype were 40% for M1, 63.3% for M2, 0% for M3, 60% for M4, and 66.7% for M5. The survival curve for the therapy regimen showed a significant relationship (p <0.05), with 86.7% survival for daunorubicin and 47.1% for cytarabine. Conclusions. Administration of daunorubicin and cytarabine chemotherapy is a variable that significantly determines the 6-month survival of AML patients.

Demographic factors associated with awareness of patient safety among nurses in a public hospital in Makassar, Indonesia

Demographic factors associated with awareness of patient safety among nurses in a public hospital in Makassar, Indonesia

Health Education In Improving The Self-Efficacy Management Of Hypertension Patients At Dr.Chalid Makassar Hospital

Health Education In Improving The Self-Efficacy Management Of Hypertension Patients At Dr.Chalid Makassar Hospital

Nursing Research Contributes to Changes in Clinical Practice

Through my experience visiting Hazanuddin University and touring the hospitals in Makassar, I reconsidered the role of nursing research in the development of nursing technology. It will be increasingly important to train professionals to provide quality care, develop new nursing techniques through interdisciplinary research and industry-academia collaboration, and establish evidence regarding insurance reimbursement.

Characteristics of Heart Failure Patients Undergoing Intensive Care at Ibnu Sina YW-Umi Makassar Hospital in 2023

Heart failure is a non-communicable disease which is the number one cause of death every year. Heart failure is caused by several avoidable and unavoidable factors. The prevalence of heart failure patients fluctuates from year to year. Considering the high incidence of heart failure, this research was conducted to identify the characteristics of heart failure patients at Ibnu Sina Hospital Makassar in 2023. The type of research is descriptive observational. Data were analyzed via Microsoft EXCEL and presented in table form. The research results showed that the majority of heart failure patients were aged 46 – 65 years in the adult category and were male. Heart failure patients have no history of smoking, no history of diabetes mellitus, and no hypertension. The majority of patients have a history of the cause category Coronary Artery Desease (CAD). Description of the death rate in heart failure patients as many as 9 people. The conclusion is that heart failure occurs at the age of 46 – 65 years and the majority are male with factors causing Coronary Artery Disease (CAD). Further studies need to be carried out in order to obtain fairly representative data.

Total Quality Management in Improving Health Services

This research aims to determine the implementation of Total Quality Management as an effective model for realizing quality health services at Ananda Hospital Makassar. This research method is of various types qualitative with a policy approach. The data source uses primary data via instrument observations and interviews as well as secondary data through reviewing various documents. The data analysis technique uses an interactive model, namely data collection, data condensation, data presentation, and verification/conclusion. The results of this research show that the implementation of the TQM model at Ananda Makassar Hospital was not implemented optimally due to the leadership aspect of manager Hospitals are less able to organize and organize all existing resources within the hospital and the inability of the head of the hospital to collaborate and communicate well with all Ananda Hospital staff to work together. set standard work procedures that are efficient and effective and the TQM implementation factors at Ananda Hospital can run well if the hospital can optimize the implementation of communication and collaboration factors where it is hoped that the Ananda Makassar Hospital will improve the quality of service by involving patient health organizations in provide education to patients as well as collaboration in exchanging necessary medical personnel resources done Ananda Makassar Hospital to develop the competency and work skills of doctors, nurses and staff administration hospitals in collaboration with other agencies and institutions that can provide training activities.

Relationship between Tumor Infiltrating Lymphocytes and Neoadjuvant Chemoterapy Responsiveness: A Cross-Sectional Study on Breast Cancer Patients

Breast cancer is still a significant health problem in the world, with chemotherapy as an essential component in its management. Limited research on tumor- infiltrating lymphocytes (TIL) as a biomarker for the effectiveness of breast cancer treatment was conducted and is still contradictory. This study aims to investigate the relationship between TILs and the clinical response to neoadjuvant chemotherapy in breast cancer. The research used a cross-sectional study on eligible breast cancer patients in Wahidin Sudirohusodo Hospital in Makassar. TIL levels were grouped based on the histopathological examination results of breast tissue samples into three categories: low (0% to 10%), medium 15% to 50% and high (55% to 100%). Responsiveness was assessed based on changes in tumor size after neoadjuvant chemotherapy. The Chi-Square test is the primary analysis in this study. Results of 40 participants, the sample had a median age of 40 (27-73 years), mainly in the clinical stage III (40.0%), had moderate TIL concentration (47.5%), and was responsive to the neoadjuvant chemotherapy (87.5%). There was no significant association between TIL concentration and chemotherapy responsiveness (p > 0.05). However, in post-chemotherapy conditions, the median value of tumor size in the group with the high TIL category was significantly lower than in the low and medium TIL groups (p=0.034). There was no association between TIL levels and the clinical response to neoadjuvant chemotherapy in breast cancer patients. Further research is needed to confirm these findings.

Blood Urea Nitrogen-Serum Albumin Ratio As a Predictor of Clinical Outcome in Acute Ischemic Stroke

Stroke is a global health issue with high morbidity and fatality rates. Treatment decisions for ischemic stroke rely on clinical outcome prediction. The NIHSS score is commonly used to predict the AIS's clinical outcomes. However, its use is hindered by its complexity, which requires the assessment of many variables. Therefore, there is an urgent need to develop a simpler yet still effective evaluation tool in assessing the AIS’s clinical outcome. The study aimed to predict AIS outcomes using the blood urea nitrogen to albumin serum ratio (RBA). This study was a prospective cohort study design, with subjects being first-time AIS patients hospitalized at RSUP Dr. Wahidin Sudirohusodo and several hospitals in Makassar from December 2022–April 2023. Demographic and clinical data were collected, assessing RBA and comparing it according to the good (mRS 0-2) and poor (mRS 3-6) outcome groups. RBA performance was assessed by receiver operating characteristic curve (ROC) analysis to assess the AIS's clinical outcome. The study's findings on 62 participants meeting the criteria revealed a significant association between RBA and the AIS's clinical outcome (p-value=0,0004). The mean RBA differed significantly between the good and poor AIS outcome groups (p-value =0,006). In the ROC analysis, the area under the curve (AUC) was 0,75 with an optimal cut-off value was 2,05, yielding a sensitivity of 41,67%, a specificity of 98%, and a likelihood ratio of 20,83 (p-value=0,007). In conclusion, RBA can be used as a simple and objective tool to determine the clinical outcome predictors of AIS.

The Influence of Service Quality, Customer Relationship Management (CRM), and Image on Patient Satisfaction and Service Marketing Performance at A Type B Private Hospital in Makassar

Purpose: The overarching purpose of this research encompasses a multifaceted examination aimed at understanding various factors influencing patient satisfaction and service marketing performance in private hospitals in Makassar. Specifically, the objectives are to explore the impact of service quality, customer relationship management (CRM), and image on patient satisfaction, as well as to analyze their influence on service marketing performance. Methods: Primary data for this study were collected through a survey conducted among 160 inpatients across four Type B private hospitals in Makassar. The survey was administered between April and June 2022. Data analysis was conducted using Structural Equation Modeling (SEM), a statistical technique utilized to examine complex relationships among variables. Results and Discussion: The findings of the research revealed several significant insights: (1) Service quality, CRM, and image each had a direct impact on patient satisfaction at private hospitals in Makassar. (2) Furthermore, patient satisfaction was found to significantly influence service marketing performance. (3) Additionally, the study identified indirect effects, such as the influence of service quality, CRM, and image on service marketing performance mediated through patient satisfaction. Implications of the Research: These findings hold important implications for private hospitals in Makassar. Understanding and enhancing service quality, CRM practices, and image perception can directly contribute to improving patient satisfaction, which in turn positively impacts service marketing performance. By recognizing and addressing these factors, hospitals can better align their strategies to meet patient needs and enhance overall performance. Originality/Value: This research contributes to the existing literature by providing comprehensive insights into the dynamics between service quality, CRM, image, patient satisfaction, and service marketing performance in the context of private hospitals in Makassar. The study's findings offer valuable guidance for hospital management in devising effective strategies to optimize patient satisfaction and enhance service marketing outcomes, ultimately improving overall organizational performance.

Anxiety Levels of Preschool Children on the Effect of Play Therapy Due to Hospitalization at Makassar City Hospital

Hospitalization is often the first thing children have to face, especially during the early years, especially vulnerable to illness and hospitalization crises due to stress due to changes in health conditions, as well as children have a limited number of coping mechanisms to resolve stressors. The intervention This can be done, one way is by playing activities or play therapy. In sick condition or the child is hospitalized, this play activity is still carried out but must be appropriate with the child's condition. With games, children will be released from tension and stress experienced, because by playing children will be able to divert the pain on the game and relaxation through the pleasure of playing the game. The aim of this research is to determine the effect of play therapy on levels worry child on age preschool consequence hospitalization in Makassar Hospital. This research uses quantitative research methods with design study quasy experiment. Population in study This is all over child preschool in the Makassar Hospital Treatment Room with a sample of 20 pre-school children. From the results of the Wilcoxon test which was carried out with a value of p = 0.008, means mark p more small from α (0.05) Which show There is change response worry child before given therapy play And after given play therapy. Researchers hope for hospitals to implement play therapy to reduce anxiety levels in children and this research can be useful for respondents, especially parents, that play therapy very helpful for child in reduce level worry.

Quality of Life of Emergency Department Nurses in Makassar Hospitals on Work Stressors and Job Satisfaction

Hospitals as organizations can place clients and caregivers under a serious burden of stress, which then affects their physical and emotional health. Working conditions in nursing show that work stress can have a big impact on the quality of life of nurses. The aim of this research was to determine the relationship between work stress, job satisfaction and individual characteristics with the quality of life of nurses in the Emergency Unit at Makassar General Hospital. The research method is descriptive using a cross sectional design with a quantitative approach. The results of the study concluded that there was a relationship between age (p value = 0.04), marital status (p value = 0.02), work stress (p value = 0.004) and job satisfaction (0.04) with the quality of life of nurses. However, there was no relationship between gender (p value = 1.00) and level of education (p value = 0.9) with nurses' quality of life. The most dominant factor related to quality of life is work stress. Work stress will affect the quality of life of nurses who work in the emergency room. Work stress affects the quality of life of emergency room nurses. Job satisfaction is related to the quality of life of emergency department nurses. The nurse's age is related to the quality of life of emergency department nurses. The gender of the nurse is not related to the quality of life of emergency department nurses. Nursing education is related to the quality of life of emergency department nurses. Nurses' marital status is related to the quality of life of emergency department nurses.

CHARACTERISTICS OF RETINOPATHY OF PREMATURITY IN MAKASSAR BETWEEN JANUARY 2020 AND DECEMBER 2022

Introduction & Objectives : Introduction: Retinopathy of Prematurity (ROP) is one of the leading causes of irreversible visual impairment in infants, especially in premature infants. Preterm birth leads to incomplete development of retina that will cause ROP. ROP screening is an early strategy to prevent irreversible blindness in ROP. Objective: The purpose of this study was to describe the characteristics of ROP in Makassar between January 2020 and December 2022.
 Methods : A multi-center observational descriptive study at ten hospitals in Makassar.
 Results : The total patients in this study were 168 infants (336 eyes) included 53.25% male and 46.15% female. The incidence of ROP in Makassar between January 2020 and December 2022 was 14.87%. Most of the patients had history of preterm birth with gestational age ranged from 28 to 33 weeks and low birth weight less than 1500 gram in 50% patients. Majority of patients had history of oxygen therapy (77.98%), and other risk factors such as sepsis, twin birth, history of transfusion, or apnea. About 98.81% patients had bilateral ROP and 33.93% were diagnosed with stage 3 at first screening. Photocoagulation laser was done in 41 patients (24.40%).
 Conclusion : The ROP screening in Makassar had a good outcome in managing the premature infants, so they can be diagnosed and got treated earlier. A sustainable screening program is required to prevent the irreversible blindness due to ROP.

Validating the use of clinical MSCT scans for cranial nonmetric sex estimation in a contemporary Indonesian population

There is renewed interest in Asia for the development of forensic anthropological standards, partly due to the need for population-specific models to maintain high classification accuracies. At present, there are no known studies utilising morphoscopic standards specific to the Indonesian population. Craniometric analyses can often be time-consuming; morphoscopic assessments are quicker and are also known to be reliable and accurate. One of the most utilised morphoscopic standards for the estimation of skeletal sex is that of Walker (2008). Its application across population groups demonstrated reduced accuracies outside of the United States; population-specific predictive models would thus serve to improve the identification process of unknown skeletal remains. Digital imaging also allows for the validation of standards on a contemporary population and is an appropriate proxy to physical skeletal material.The present study quantifies the applicability of the Walker standard to a contemporary Indonesian population. A total of 200 cranial MSCT scans from a hospital in Makassar were analysed using OsiriX®. Scoring was performed in accordance with the Walker standard. Five univariate and nine multivariate predictive models were derived using single trait and multi-trait combinations. The best performing univariate model included the glabella, with a total classification accuracy of 82.0% and a sex bias of 14.6%. Classification accuracy with all traits considered was at 95.2% for females and 82.8% for males with a sex bias of 12.5%. These results provide forensic practitioners in Indonesia with an appropriate morphoscopic sex estimation standard, strengthening their capabilities in the field and improving judicial outcomes.

The severity of distal sensory polyneuropathy increasing with HIV/AIDS stage.

Distal sensory polyneuropathy (DSP) is the most common neurological problem in HIV/AIDS Patients. It represents a complex symptom that occurs because of peripheral nerve damage related to advanced HIV disease and in association with the use of antiretroviral therapy. DSP is a frequent symptom in which the specific pathophysiology is not well understood. Recently, mitochondrial toxicity and antiretroviral toxic neuropathies have been more identified as a possible etiology of DSP. This study's objective was to determine factors associated with DSP severity in HIV/AIDS patients. This cross-sectional study was followed by 50 HIV/AIDS outpatients at some hospitals in Makassar, Indonesia who met the inclusion criteria. DSP is diagnosed using non-invasive screening tools subjective peripheral neuropathy screen (SPNS) which can determine the severity of DSP in advance. Some factors were analyzed by using Pearson's chi-square test and Spearman's correlation test. Forty-three participants (86%) had diagnosed DSP which is mostly moderate in severity (48%). Statistical analysis showed significant correlation between HIV/AIDS Stage and DSP severity (p=0.032) meanwhile CD4 count, antiretroviral, body mass index (BMI), and hemoglobin level have no significant correlation to DSP severity. In conclusion, HIV/AIDS stage and DSP severity correlate where the later the stage the more severe DSP.

Analysis of Knowledge and Nurse Competencies Related to Advanced Care for Trauma Patients in the Emergency Room in South Sulawesi

The Emergency Room is a unit that provides initial treatment for trauma patients. Trauma cases contribute to disability and suffering, making it the fourth leading cause of death worldwide. In 2021, the prevalence of trauma-related deaths was approximately 4.4 million people globally, with 8% of cases resulting in death. This phenomenon highlights the importance of health workers, possessing specialized knowledge and competence in emergencies, including triage, primary,and secondary assessment. The purpose of this study is to analyze the relationship between knowledge and nurse competence in providing follow-up care for trauma cases at the ER in South Sulawesi.The research method utilized in this study is quantitative, employing a cross-sectional approach with a total sample of 37 respondents selected through the total sampling technique. The research was conducted at Ibnu Sina Hospital and Bayangkara Hospital in Makassar. Data were collected through questionnaires and competency observation sheets, and subsequently tested using a correlation test.The results of the univariate test indicate that nurses possess good knowledge in various aspects of follow-up care, including triage, primary survey, and secondary survey. Additionally, their competencies in these areas are also well-developed. The correlation test revealed significant relationships between knowledge and triage competence (p-value of 0.01), knowledge and primary survey competencies (p-value of 0.047), as well as knowledge and secondary survey competencies (p-value of 0.04). These findings suggest that a higher level of knowledge among Emergency Room nurses regarding follow-up care corresponds to better competence in managing trauma cases in the emergency room. In this study, it can be concluded that there exists a relationship between nurses' knowledge regarding follow-up care and their competence in three aspects: triage, primary survey, and secondary survey. Based on these findings, it is recommended that nurses can enhance their competencies through training and can apply high-quality cardiopulmonary resuscitation to improve patient safety.

Quality of Liquid Waste at the General Hospital in Makassar

Hospital waste is all waste produced by hospital activities and other supporting activities. Considering the impacts that may arise, good management efforts are needed including tools and facilities, finances and organizational procedures that are determined with the aim of obtaining hospital conditions that meet environmental health requirements. The research used was observational with a descriptive approach, namely to determine the quality of liquid waste in hospitals in Makassar. This research was conducted from 20 to 27 June 2021 at the Hospital in Makassar. The population is liquid waste in hospitals in Makassar in 2021. The sample in this study is hospital effluent waste in Makassar in 2021. Waste water that is not handled properly will result in negative impacts, especially for health, so it needs good management so that when it is disposed of in A certain area does not cause pollution which is supported by the wastewater treatment plant (IPAL) owned by the hospital itself. It was concluded that the DO levels in the liquid waste produced were at a vulnerable level. The BOD level in liquid waste in the morning is at a moderate level and in the afternoon it is at a heavy level. COD levels in Makassar liquid waste in the morning are at moderate levels and in the afternoon at heavy levels. TSS levels in liquid waste in the morning are at moderate levels and in the afternoon they are at heavy levels. The pH level in liquid waste meets the requirements. TEMPERATURE levels in liquid waste meet the requirements.

Survival Analysis with Cox Proportional Hazard Model for Tuberculosis (TBC) Patients

Survival analysis is a method in statistics which aims to analyze the relationship between time from thebeginning of observation until the occurrence of an event (response variable) with factors that have aninfluence on the event (predictor variables). To determine the relationship between the response variableand the predictor variable, where the response variable is the time until the event occurs, one method thatcan be used is the cox proportional hazard regression method. The data used in this research is data onhospitalizations of tuberculosis sufferers at Haji Makassar Hospital in 2022 because it has characteristicsthat are in accordance with the aim of survival analysis, namely to determine the relationship betweenthe life span of TBC patients and the factors that influence TBC disease. The results of the analysisobtained factors that significantly influence the recovery rate of patients with TBC are shortness ofbreath and smoking habits. The shortness of breath variable has an influence on the recovery rateof TBC patients, namely 0,3506, which means that TBC patients who do not experiencing shortnessof breath has a recovery rate of 0.3506 times the likelihood of recovery compared to patients whoexperience shortness of breath. Variable smoking habit was 0.7367, which means that patients withTBC did not smoking habit has a recovery rate of 0.7367 times recovered compared to patients who hada smoking habit

The Effect of Combination of Calcium Supplement and Physical Exercise on Increasing Muscle Strength in Chronic Ischemic Stroke

Background: Stroke causes muscle weakness which results in limitations in daily activities such as self-care, eating, walking, etc. Objective: This study aims to evaluate the effect of calcium supplement and physical exercise on increasing muscle strength in chronic ischemic stroke patients. Method: This research used a quasi-experimental pretest-posttest with control group design. This research was conducted at Dadi Makassar Hospital and Haji Hospital from March to May 2023. The sample obtained was 37 subjects based purposive sampling with an unpaired numerical comparative formula for two sample groups. Consisting of 18 people in the treatment group who were given calcium supplements at a dose of 500 mg per day and physical exercise (Both training, Proprioceptive Neuromuscular Facilitation (PNF) and strengthening) and 19 people in the control group who were only given physical exercise. The research was carried out for 6 weeks using a Manual Muscle Testing (MMT) measuring instrument for muscle strength. This research used the Wilcoxon and Mann Whitney test. (α<0.05) Results: There is a significant of increasing lower extremity muscle strength between pretest and posttest in treatment group and control group (p=0.001; p=0.014, p<0.05), There is an increasing of the upper extremity muscle strength between pretest and posttest in treatment group and control group (p=0.001; p=0.025). There is no significant difference of increasing muscle strength in the upper and lower limb between two groups (p=0.051). Conclusion: Calcium supplements and physical exercise were no more significant in increasing muscle strength than physical exercise only in chronic ischemic stroke patients.