Background: The increasing incidence of Coronavirus Disease 2019 (COVID-19) in Indonesia affects the need for hospital inpatient services. One of the parameters of service quality and the use of hospital resources is the length of stay (LOS). Objective: To find the determinants of COVID-19 that affect LOS in hospitals. Methods: Retrospective observational data collection using a cross-sectional study design. The sampling method used was total sampling during the January-August 2021 hospitalization period in the Isolation Room of the General Hospital of Jend. A. Yani Metro City. The data used is medical record data. Bivariate analysis uses Chi Square, while multivariate analysis uses Multiple Logistics Regression. Results: The sample consisted of 443 patients who were treated during the period January-August 2021 in the COVID-19 isolation room at RSUD Jend. A. Yani Metro City. The median LOS is 6 days. Multiple logistic regression analysis shows that the determinants of LOS include severity, diabetes mellitus, heart disease, and D-Dimer. Conclusion: Severity, comorbid diabetes mellitus, comorbid heart disease, and D-Dimer value are the determinants of LOS in confirmed COVID-19 patients in the COVID-19 isolation room at General Ahmad Yani Hospital, Lampung Province. Keywords: Determinants, Coronavirus Disease, LOS, hospital
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