Hospital Bangalore Research Articles

Clinical profile and outcome of snake bite in children admitted in a tertiary care institute in the metropolitan city of Karnataka, India

Background: Snake bite is a major medical and public health problem in tropical agricultural world. A high incidence of snake bite envenomation has been reported from rural India, many times the incidence is underestimated due to lack of epidemiological information. The present study analyses the age, mode of presentation, seasonal variation, clinical profile, management and outcome of patients with snake bite in below 18 years of age group of a metropolitan city, India.Methods: This study is a retrospective single centre study conducted in government referral hospital in Bangalore from January 2016 to January 2020 including 53 patients, who presented with a history of snake bite. Clinical data about age, sex, clinical manifestations, complications, management and outcome were analysed.Results: In our study including of 53 patients, maximum snake bites incidents were noted in age group of 6-10 years (47.16%) of the rural population with male predominance (83.01%). Most of the bites occurred during monsoon season (54.71%) in evening time. Bite marks were observed mainly on lower limbs in 71.69% of patients. Tourniquet was the commonly used first aid care (67.92%). Most of the bites were vasculotoxic in (75.47%) followed by neuroparalytic in 15 patients (9.43%) and maximum cases responded to 20 vials of ante venom. Mortality was nil.Conclusions: Snake bite is a life-threatening emergency. The key in minimizing mortality and severe morbidity is aggressive management of sick patient and timely as well as judicious administration of ante snake venom. There is a requirement to sensitize the general public and healthcare personnel on preventive measures, emergency care and treatment of snake bites. The serious clinical features of snake bite warrant early referral and management in tertiary care centers.

Evaluation of Rational use of Antibiotics in Medicine Ward of a Tertiary Care Hospital

: Background: Antibiotics are among the most frequently used drugs worldwide. An average 35% of the total health budget is spent on antibiotics. Overuse and/or misuse of antibiotics has significant consequences, such as increased cost, bacterial resistance, therapeutic failure, drug toxicity and drug interactions. The objective of this study was to evaluate the prescribing pattern of antibiotics in Medicine ward of a tertiary care hospital in Bangalore. Methods: Hospital based retrospective study carried out in medicine ward of a tertiary care hospital in Bangalore. A retrospective study was carried out by collecting the data of the medication orders given for a period of 12 months. A total of 741 medication order was studied of which 470 were for males and 271 for females, between the age group of 15-92 years. Results: The results showed that the most commonly prescribed class of antibiotics were: Cephalosporins 571 (47.22%), Quinolone 237 (19.6%), Cephalosporins + Penicillinase inhibitors 159 (13.15%), Penicillin + Penicillinase inhibitor 73 (6.03), Aminoglycoside 27 (2.23%), Macrolides 13 (1.07%), Sulphonamides 1 (0.08%), Tetracyclines 2 (0.16%) and others 126 (10.4%). Conclusion: The most commonly prescribed class of antibiotics was Cephalosporins. Detailed knowledge of antibiotic prescription pattern is important to monitor the rational use of antibiotics and is important before the therapeutic policies and measures can be implemented. It’s recommended to involve an active clinical pharmacist in the hospital to study the drug use pattern and intervention as and when necessary.Key words: Prescribing, Antibiotics, Rational Use, Tertiary Care Hospital, Therapeutic Policies.

Evaluation of risk factors for perinatal asphyxia in a tertiary care hospital in Bangalore: an observational prospective study

Background: Perinatal asphyxia is an insult to fetus or newborn due to lack of oxygen (hypoxia) or lack of perfusion (ischemia) to various organs of sufficient magnitude and duration. Prenatal asphyxia is one of the major causes of early neonatal mortality in India. Our goal was to evaluate risk factors of perinatal asphyxia.Methods: Observational prospective study on 100 babies delivered in our hospital consecutively and requiring resuscitation were included.Results: The mean age of mothers was 23.5 years. 54% neonates were born to primiparous mothers. Anaemia was widely prevalent in the mothers of neonates requiring resuscitation. The major maternal risk factors for newborns requiring resuscitation were pregnancy-induced hypertension (PIH) (46%), oligohydramnios (41%), polyhydramnios (30%) and meconium stained liquor (28%). The fetal factors associated with resuscitation of newborns were intrauterine growth restriction (IUGR) (30%), prematurity (25%), meconium aspiration syndrome (MAS) (20%), and neonatal seizures (36%). Mortality was highest in hypoxic ischemic encephalopathy (HIE) stage 3 with 11%.Conclusions: The most common maternal risk factors for newborns requiring resuscitation was PIH followed by oligohydramnios, polyhydramnios and meconium stained liquor. IUGR was the most common fetal risk factor followed by, prematurity, MAS and neonatal seizures.

Clinicolaboratory profile and outcome of dengue fever cases in peak season of an academic year among pediatric population admitted to teaching hospital, Bangalore, Karnataka, India

Background: Dengue is a vector borne diseases with varied clinical manifestations, a major concern to public health globally. This study was done to describe the salient clinical as well as haematological profile of serologically confirmed cases of dengue fever and outcome in admitted cases.Methods: This was a prospective study conducted at major Government teaching Hospitals in Bangalore from July 2019 to December 2019. Total 164 cases of dengue fever were enrolled and classified as per WHO guidelines. The clinical profile and demographic profile was recorded in a structured questionnaire format. Haematological parameters on admission, duration of stay and outcomes were analysed. The outcomes of the cases were mentioned as improved and death.Results: In this study commonly affected age band was adolescents group (36.6%) without any sex predilection. Maximum number of dengue cases were presented with warning signs (87.5%), 14 (8.69%) cases without warning signs and 6 (3.72%) with severe dengue. Fever was the most common symptom (100%), followed by vomiting (58%) and abdominal pain (38.5%). NS1 antigen positive cases (61.5%). Severe Leukopenia was present in 57% of cases and Thrombocytopenia in all admitted patients (100%). Most of the cases were treated with antipyretics, oral fluids (46%) and IV fluids (53%), only single case received platelet transfusion. Duration of stay was more in severe dengue cases. Mortality of our study was 1.8%.Conclusions: Dengue presents with varied clinical features. Community awareness, early diagnosis and management and vector control measures needs to be strengthened in order to reduce the increasing number of dengue case. Both clinical, haematological parameters should be monitored for better outcome.

A rare case of hydatid cyst in the breast in a tertiary care hospital in Bangalore, Karnataka, India

Hydatid disease is a well-known entity since the era of Hippocrates. Although breast is one of the rare sites for the occurrence of hydatid disease, it has been well evaluated with the various newer imaging modalities and its imaging features are well described in the literature. A 41-year-old female presented with a painless well-defined lump in the right breast without any history of pain, trauma, discharge from the nipple, fever, or drug misuse. This case was diagnosed preoperatively by FNAC, ultrasound, and was confirmed by surgery. Hydatid disease of the breast should form the part of the differential diagnosis of cystic diseases of the breast especially in an endemic country like India. Awareness of this entity can make the pre-operative diagnosis even without cytological examination, which is very helpful in the management of the patient.

Knowledge, attitude and practice among diabetic patients visiting a tertiary care hospital in Bangalore, Karnataka

Background: Diabetes mellitus is a chronic non-communicable disease which has become the epidemic of the 21st century. According to WHO 1.6 million deaths were estimated to be directly caused by diabetes in the year 2016 and attributed to be the seventh leading cause of death in the world. Objective of the study was to assess the knowledge, attitude, practice about diabetic care among the diabetic patient, and to assess the association between KAP of diabetic care and socio-demographic factors.Methods: Cross-sectional study was done with purposive sampling for 4 months, on 62 sample size. Data collection tool was the KAP questionnaire which was adapted a study by Herath HMM.Results: Out of 66 participants, 34 (51.5%) had good knowledge about diabetes, 27 (40.9%) and 5 had poor knowledge (7.6%), 16 had positive attitude about diabetes care (24.2%) and 50 (75.8%) had negative attitude, 47 had good practice about diabetes care (71.2%) and 19 (28.8%) of them had bad practice.Conclusions: Though majority of the study participants had good to moderate knowledge (92.4%), their attitude was negative (75.8%) and the knowledge level did not fully reflect into the attitude and practices (71.2%). This suggests there is a gap in the knowledge, attitude and practice.

Evaluation of Factors Determining Tracheostomy Decannulation Failure Rate in Adults: An Indian Perspective Descriptive Study.

Decannulation is an essential step in liberating tracheostomised patients from mechanical ventilation. This procedure is purely based on the clinician’s judgment and there is no universally accepted protocol to date for this vital procedure. This study aimed to describe decannulation practice and failure rates in patients with tracheostomy and to determine the factors associated with the outcome of tube removal. A prospective study was done on 50 patients (both sexes) who required a tracheostomy and cared for at Command Hospital Bangalore Center between January 2019 and April 2020. Data were analyzed using descriptive and inferential tests. Out of the 50 decannulation decisions, 7 patients experienced decannulation failures giving a failure rate of 14%. Out of the 7 decannulation failure cases, about 4 patients (10%) experienced difficulty in swallowing and 3 patients (2%) experienced stridor. There was no associated mortality. A decannulation failure of 14% was seen in this study in tracheostomised patients after prolonged mechanical ventilation. Various factors govern the success of tracheostomy decannulation procedures which occur during the first 24–48 h after decannulation. Lack of swallowing/secretions/cough management and the development of stridor were the commonest cause of decannulation failure in this study.

Efficacy of modified Judet's technique in non union tibia, with inter locking nail as fixation device

Methodology: A total 20 Patients of Victoria Hospital and Bowring & Lady Curzon hospital Bangalore during the period from 2017 to 2019 with aseptic non-union tibial fractures are taken for study. All cases were treated with opening of fracture site, freshening of fracture edges and raising of osteoperosteal flap followed by internal fixation with interlocking nail. The cases were followed for post operatively at 4 weeks, 12 weeks and 24 weeks.

Seroprevalence of transfusion transmissible viral infections in blood donors of tertiary health care hospital in Karnataka

Backgraound: Blood transfusion and its components are significant in saving millions of lives around the worldwide every year. Few, but serious complications are associated with Blood transfusion such as exposure to transfusion -transmissible infections (TTI), in particular: Human immunodeficiency virus(HIV)Hepatitis B Virus(HBV), Hepatitis C virus (HCV). Therefore, methodical pre transfusion testing of blood units for transfusion transmissible diseases is compulsory as per National Aids Control Organization (NACO) guidelines. Objective: To evaluate the prevalence of transfusion transmissible viral infections among blood donors in our tertiary health care hospital in Bangalore, Karnataka. Materials and Methods: The study comprised of retrospective analysis of blood donor’s records covering from January 2015 to December 2018 (4 years) in the department of Blood bank, Sanjay Gandhi institute of trauma and orthopedics, Bangalore. Results: A total of 8728 blood donors were screened for TTIs between 2015 to 2018. Conclusion: Although there were a smaller number of transfusion transmissible viral infection among blood donors, methodical and comprehensive screening of donor’s blood for HIV, HBV and HCV using standard methods are essential to ensure the safety of blood to the recipients. Keywords: Sero prevalence, Transfusion transmitted infections, Blood donors.

A Study on Prescribing Pattern of Antihypertensive in Chronic Kidney Disease Patients

Background: Chronic kidney disease causes progressive loss of function which gradually occur overtime leading to decrease in GFR levels leading to dysfunction of renal system. Hypertension is found to be intermingled cause and overlapping complication in CKD. It is important to intervene the progression by controlling the blood pressure to prevent kidney failure by administration of anti-hypertensive. Objectives: To study current trends in anti-hypertensive prescription pattern in CKD patient and to evaluate the concurrent patterns are in adherence according to the guidelines mentioned. Methods: Prospective observational study was undertaken in patients who were satisfying the inclusion criteria and was enrolled into the study conducted for a 6months period in a tertiary care hospital in Bangalore. Results: 150 CKD patients were examined out of which 72% prevalence seen in males compared to females 28%. Dual drug therapy was most preferred combination seen in 48% of the prescriptions. CCB was the most preferred class of drug and least preferred class of drug was ACE. More than 85% deviation from JNC-8 was seen. 20% of mono-therapy was found in adherence to JNC-8. Conclusion: A 15% adherence to JNC-8 guidelines was observed in the treatment indicating need for clinical pharmacist who play vital role in management of CKD by adherence to JNC-8 to ensure safety, efficacy and rationality.
 Keywords: Chronic kidney disease, Hypertension, Prescription pattern, JNC-8 guidelines, Compliance, Anti-Hypertensive.

Do Low Self-Esteem and High Stress Lead to Burnout Among Health-Care Workers? Evidence From a Tertiary Hospital in Bangalore, India.

BackgroundLow self-esteem can be an issue among health-care workers due to the hierarchical medical system. Health-care workers are also in a high pressure environment that can lead to stress and burnout. This study was conducted to estimate the proportion of health-care workers with low self-esteem, high stress, and burnout and the factors associated with these in a private hospital in Bangalore city.MethodsThis cross-sectional study included a random sample of health-care workers of various cadres – doctors, nurses, nursing aides, technicians, and workers in ancillary departments such as laundry, dietary, central sterile supply department, and pharmacy, with probability proportional to size. Rosenberg Scale for Self-esteem, Cohen's Perceived Stress Scale, and Shirom–Melamed Burnout Measure were used as study tools.ResultsAmong the 306 health-care workers, there were high levels of low self-esteem (48.4%), stress (38.6%), and burnout (48.7%), with the lowest levels being among doctors. Those aged younger than 30 years had significantly lower self-esteem and greater stress.ConclusionsHealth-care workers with low self-esteem were nearly thrice more likely to suffer high stress, Odds Ratio (OR) = 2.84 (1.36–5.92), and those who were stressed had more than three times higher chance of experiencing burnout, OR = 3.6 (2.02–6.55). Path analysis showed that low self-esteem among health-care workers had a direct effect on burnout, as well as an indirect effect through stress (mediator variable). This study indicates the need for screening and counseling for low self-esteem, stress, and burnout as part of a periodic medical examination of all cadres of health workers.

Clinical spectrum of pneumonia in children aged 1 month to 18 years by serum polymerase chain reaction, in a tertiary care centre in Bengaluru, Karnataka, India

Background: Pneumonia accounts for 15% all deaths in children under 5 years of age, being the single largest infectious cause of deaths in children worldwide according to WHO. Establishing the exact etiological factor is a difficult task, as there are no definite clinical, radiological markers to differentiate between causative organisms. Hence by detecting the genetic material of causative organism by serum PCR (polymerase chain reaction) and correlating it with the clinical and radiological features can help in appropriate use with antibiotics.Methods: It is a observational study conducted in department of paediatrics KIMS hospital Bangalore, India which included inpatients admitted with clinical and radiological features of pneumonia over a study period from February 2018-April2019 .In this study we excluded immunocompromised children . After obtaining informed written consent, detailed history and clinical examination was done. Investigations including complete hemogram, CXR were done. Under sterile precautions, blood samples for serum PCR and blood culture and sensitivity were obtained. Serum PCR was done for a panel of 33 respiratory pathogens.Results: Etiological agents were identified in 63% of cases. Streptococcus pneumoniae was the most common causartive agent being detected in 50.6% of the cases. Staphylococcus aureus has been detected to be the second common organism 16%.Conclusions: In our study Pneumococci was identified in 50.6% of cases. Multiplex serum PCR could be a useful rapid diagnostic tool to identify the etiological agents. Introduction of pneumococcal vaccine worldwide in government immunization schedule, nationwide will help to reduce the disease burden caused by Streptococcus pneumoniae.

Application of six sigma and 5 S to improve medication turnaround time

ABSTRACT Purpose: The purpose of this study is to improve the medication turnaround time of a tertiary care hospital in Bangalore. The goal for improvement was set as 1 h based on the voice of external and internal customers and benchmark of two studies where the improvement results were 70 min and 66 min. Background: There is documentary evidence that timely administration of medicines such as antibiotics results in a significant decrease in mortality and length of stay. The increased length of stay increases the cost of treatment for the patients and reduces the bed turnover rate for the hospital. Method: DMAIC approach of Six Sigma together with the ‘Seiton’ principle of 5 S quality tool is used to reduce the medication turnaround time and to improve the sigma level of the process. Results: At the end of the study the mean total turnaround time of 1 hr 29 min got reduced to 48 minutes and the sigma level got improved from 1.22 sigma level to 2 sigma level. Conclusion: This study showcases that Six Sigma and 5 S can be used effectively to reduce the medication turnaround time, which enables in achieving the long term goals of patient satisfaction.

Analysis of antibiotic usage for surgical prophylaxis in a tertiary care hospital in Bangalore, Karnataka, India

Introduction: Appropriately administered antibiotic prophylaxis reduces the incidence of surgical wound infection. The timing of antibiotic administration is very critical. The first dose should always be given before the procedure, preferably within 60 minutes before incision. Re-administration at one to two half-lives of the antibiotic is recommended for the duration of the procedure. In general, postoperative administration is not recommended except for cardiothoracic surgeries. Materials and Methods: This is a retrospective study done over a period of 6 months from January 2019 to June 2019 in a tertiary care hospital in Bangalore. A continuous 100 patients who underwent an elective surgery were audited regarding the antibiotic indication, choice, dosage, dosing interval, and timing of first antibiotic administration prior to skin incision and duration of prophylaxis were compared with the CDC guideline recommendations and hospital antibiotic policy. Results: A total of 100 surgeries were audited. Out of this, 4% were clean 84% were clean contaminated 4% were contaminated and 8% were dirty. The most commonly used antibiotics were cephalosporins 74% aminoglycosides 36%, β lactams 14%, and fluoroquinolones 2%. The three parameters tested for adherence showed individual compliance of 92% for appropriate selection of antibiotics, 85% for the appropriate administration, and 56% for the appropriate duration of antibiotics, respectively. Conclusion: The results highlight the challenges of disseminating evidence-based protocols systematically into routine clinical practice. Various measures are needed to improve appropriateness of prescriptions and adherence include the development of evidence-based guidelines in collaboration with surgeons, increased outcome-based research to document benefits of appropriate antibiotic use, continuing education to disseminate information to practitioners etc.

Comparison of Preemptive Effect of Dexamethasone and Methylprednisolone After Third Molar Surgery: A Split-Mouth Randomized Triple-Blind Clinical Trial.

The study aimed to compare the efficacy of methylprednisolone and dexamethasone injected into masseter muscle preoperatively in surgical extraction of lower third molars. This study was carried out on 20 patients who reported to the department of Oral and Maxillofacial surgery, Sri Rajiv Gandhi College of Dental Sciences and Hospital Bangalore, requiring surgical removal of bilateral mandibular third molars. The efficacy of corticosteroid was evaluated based on its ability to reduce pain, swelling and trismus following the surgical extraction of impacted lower third molars. There was no statistical difference between the two steroids with both of them achieving equal level of pain control. There was a statistically significant difference on the second postoperative day with dexamethasone showing clinically superior result. The difference in oral aperture was found to be statistically significant with dexamethasone showing a decreased reduction in postoperative mouth opening on both second and seventh day. This study conclusively proves that patient comfort levels are far better with the use of dexamethasone.

Base excess as a prognostic factor determining the perinatal outcome

Background: Umbilical cord blood gas assessment seems to be the most objective determination of fetal metabolic condition at the time of birth and can be used to assess the perinatal outcome of the baby. In the early stage of an impaired placental circulation, hypoxemia and hypercapnia result in a decrease in pH with BD maintained normal (respiratory acidemia), whereas if the hypoxic process develops into a sustained anaerobic metabolism the BD rises secondary to lactic acidosis and consumption of buffer.Methods: Observational study done in KIMS hospital Bangalore, Karnataka, India, in a study period of 18 months on a sample size of 100. Within 30 sec of delivery a segment of umbilical cord was clamped at both ends. Cord blood was collected in heparinised syringe. It was then transported with cold ice packs and blood pH, pCO2, pO2 were measured.Results: In present study, there was a significant difference between the 2 groups in terms of BE, BE being highest in the group without complication. There was a moderate negative correlation between duration of NICU stay (days) and BE (mmol/L), and this correlation was statistically significant. There was a significant difference between the 2 groups in terms of BE with the median BE (mmol/L) being highest in the group not requiring resuscitation. At a cutoff of BE (mmol/L) <-17.5, it predicts complications with a sensitivity of 71.4%, and a specificity of 88.2%.Conclusions: Hence cord blood base excess can be used as a prognostic factor in determining the perinatal outcome.

Correlation between umbilical cord blood pH and meconium stained deliveries

Background: Among all live births approximately 13% neonates are born through meconium-stained amniotic fluid and out of these 5-10% developed MAS, which increases neonatal morbidity and mortality. The incidence increases as the gestational age advances with reported frequencies at 37, 40, and >42 weeks being 3%, 13%, and 18% respectively. Although there is a significant decrease in the occurrence of MAS and associated mortality in developed countries, MAS remains a major problem in developing countries. The objective was to study the correlation between umbilical cord blood PH and Meconium stained amniotic fluid.Methods: Observational study done in KIMS hospital Bangalore, Karnataka, India in a study period of 18 months on a sample size of 100. Within 30 sec of delivery a segment of umbilical cord was clamped at both ends. Cord blood was collected in heparinised syringe. It was then transported with cold ice packs and blood pH, pCO2, pO2 were measured.Results: In present study population, among those with MSAF, 72% had acidemia and 28% did not have acidemia. The mean (SD) of pH in the group with MSAF was 7.16 (0.10). The median (IQR) of pH in the group with MSAF was 7.14 (0.12). There was no significant difference between the groups (those with MSAF and those without MSAF but other risk factors) in terms of pH (W = 867.500, p = 0.580).Conclusions: The presence of acidosis in the umbilical cord blood, used as a biochemical marker for perinatal asphyxia can be used to evaluate the significance of intrauterine passage of meconium. But a normal acid-base status at delivery present in many cases of MSAF, suggests that either a pre-existing injury or a non-hypoxic mechanism is often involved. MSAF is not always secondary to an acute hypoxic event.

Incidence, microbiological profile and outcome of ventilator-associated events in a tertiary care hospital in Bangalore, Karnataka, India

Introduction: Despite different ICU admission causes, ventilator-associated event (VAE) is still a common cause of mortality and morbidity in intubated patients and impedes obvious progression in diagnostic modalities and management of these infections. Objectives: The aim of this study was to estimate VAE incidence, detection of antimicrobial resistance pattern’s which can help in the management and to follow the outcome of the patients having VAE. Materials and methods: This was a retrospective study done over a period of 24months from January 2018 to December 2019 in a tertiary care hospital in Bangalore. The study population included all the confirmed VAE patients. Their incidence of microbiological profile and the outcome was noted. Results: Out of 422 mechanical ventilated (MV) patients 71 patients developed VAE. In the 71 proved VAE cases 48 (67.6%) were male and23 (32.4%) were females. Out of 71 cases, the mean age who were having VAE falls in the range of 65- 75 yrs. The incidence of VAE is 16.82 and the incidence density:9.78 /1000 ventilator days. Klebsiella pneumonia (29.5%) was the common organism isolated among 71 cases. Conclusion: Utilizing the preventive, diagnostic, and treatment recommendations outlined should allow for improved outcomes for a common and serious medical complication seen in ICU mechanically ventilated patients.

Socio- Demographic Study of Deaths Due to Poisoning in Autopsies Conducted at KIMS Hospital, Bangalore

Poisoning is a common day to day problem. Profile of poisoning in an area depends upon a variety of factors, ranging from access to and availability of poison, socio-economic status of the individual, cultural and religious influences, etc. A prospective study was carried out in the Department of Forensic medicine, Kempegowda Institute of Medical Sciences and Hospital Bangalore to study the socio- demographic profiling of deaths due to poisoning. Out of the 100 cases studied, incidence of poisoning was found to be more amongst the age group of 21 to 30 years in both sexes with mean age being 25.4 years and 25.4 years amongst males and females respectively. Poisoning is more in males (68%) as compared to females. In both the sexes, married (68%) outnumbered the unmarried in rural and urban community. This study shows that maximum number of poisoning cases were noticed among Upper Lower socio economic Class and in Nuclear families(61%). It was observed that majority of the victims were Graduate (28%).Financial constraints(22%) were the most common motive behind poisoning deaths.

Using Multiple Regressions to Predict (ICU) Intensive Care Unit Nurses Professional Detachment Intent, in Bangalore Multi-Specialty Hospitals, Karnataka

Background/aim: This paper aimsto determine the predictors of ICU nurses intent for professional detachment in Bangalore. It also focuses on identifying the factors which, influence nurses intent to professionally detach from the organization. Materials and methods: A questionnaire survey of 462 nurses employing in multispecialty hospitals in Bangalore was sampled to test the hypothesis. The Health Profession Stress Inventory Scale and the Nursing Stress Scale measures the problem researched. Scale scores were analyzed statistically. Results: The results from Stepwise Multiple Linear Regression showed that nurse person-organization fit, conflict, responsibility & recognition for nurses predict the professional detachment intent of nurses with its standardized β coefficients (β=-0.338; p<0.01), (β=0.142; p<0.05) and (β=-.173; p<0.01) respectively.Conclusion: The present study highlights that there are many factors predicting the professional detachment intent of ICU nurses, more concerned the p-o-f of nurses largely predicts their intent to be professionally detached.