Mixture Of Honey Research Articles

Immunomodulatory activity of Swarna Prashana (oral administration of gold as electuary) in infants - A randomized controlled clinical trial.

Background:Swarna Prashana (oral administration of gold as electuary) is a form of electuary depicted in the classics of Ayurveda under the ambit of pediatrics. A specific action on immune system has been highlighted in infants if gold is administered along with Ghrita and honey for a period of 28 days.Aim:The present trial was conducted to assess the safety and efficacy of Swarna Bhasma (calcined powder), Madhu (honey) and Ghrita in infants with respect to anthropometrical, hematological and immunological parameters.Methodology:The trial was a randomized, controlled, single-blind study in 102 healthy infants allocated into trial and control groups. Trial group received a mixture of Swarna Bhasma, honey and Ghrita, while control group received a mixture of honey and Ghrita, both in drops form for a period of 4 weeks with 8 weeks follow-up. Safety was assessed on the basis of biochemical parameters and efficacy was based on the values of IgG before and after the treatment.Results:Anthropometrical and biochemical parameters did not showed any statistically significant difference between the effect of trial and control drugs, which suggested that the trial drugs did not hamper normal growth of the infants and were safe to be administered in infants. Both trial and control drugs showed statistically significant changes in IgG levels individually before and after the treatment; however, when compared between the groups, there was no significant differences. However, the number needed to treat (NNT) to assess the normalization of immunoglobulins, which is suggestive of its immunomodulatory activity, was 1 out of every 4.535 infants who received Swarna Prashana which was significant.Conclusion:Swarna Prashana did not interfere with normal growth of the infants. As evident by NNT, it showed immunomodulatory activity and was tolerated by the infants with no adverse effects during the trial or follow-up period.

Determination of Adulteration of Honey Syrup Using Open Ended Coaxial Probe Sensor at Microwave Frequency

Food quality assurance is becoming increasingly important in food processing industry as expectations from the consumers and competitions among food manufacturers continue to grow. For this singular reason, this research work is primarily aimed at studying the dielectric characteristics of pure honey and adulterated ones with a view to determine honey that has been adulterated. In this work, permittivity of pure honey, distilled water and honey—distilled water syrup mixtures with water content from 0% to 80% was studied from 1 to 20 GHz with open-ended coaxial-line sensor and a network analyzer at room temperature. The input reflection coefficient obtained from the vector network analyzer (Agilent 85,071) is then used to calculate and correlate the complex permittivity measured for the water and mixtures. Results showed that the die-lectric constants of all samples decreased with increasing frequency, while the pure honey had lower dielectric constant than distilled water but the mixture of water and honey increased with increases in water content. The maximum loss factor decreased with increasing water content.

Effects of royal jelly and honey mixture on some hormones in young males performing maximal strength workout

Background and Study Aim: Among products used as ergogenic substances by sportsmen, royal jelly and honey have attracted attention in recent years. This study was carried out to determine the effect of royal-jelly and honey mixture on weight lifting performances and some hormone test of athletes. Material and Methods: Randomly selected healthy 29 athletes, aged between 20 and 25 years, were divided into two groups. Placebo (corn starch) was given to the Control Group and 5 grams of royal jelly + 45 grams of honey mixture was given to the experimental group for eight weeks. After one week of weight adjustment workout; maximum weight (bench press, shoulder press, squat, deadlift and arm curl movements) that each athlete can lift was determined and hormones (Free T4, Free T3, Cortisol, Insulin, Total Testosterone and ACHT, TSH, Growth Hormone, Prolocatin, FSH, LH) were examined at pro-exercise, after four weeks of exercise, and after eight weeks of exercise. Results: As a result of the study, a statistical increase in the weights lifted in the bench press, squat, arm curl, deadlifts and shoulder press movements in the second and third measurements with respect to the first measurement was determined within both groups (p<0.001). While according to the hormone test results in placebo and experimental groups, there was no significant difference in free T3 , total testosterone variables intra-groups and inter-groups (p> 0.05), but there was significant difference in free T4 value in 2. measurements of groups (p = 0.030) and between the 2. and 3. measurements in the test group in the variable of insulin hormone (p <0.001). Conclusions: In conclusion, it is thought that in young males performing maximal strength workout, royal jelly + honey supplement does not affect the increase in weight lifted, this increase is due to the weight training applied, but it causes some hormone changes.

Magnetorheological bio-suspensions membranes: Influence of magnetic flux density on the electrical conductivity and relative dielectric permittivity

Magnetorheological bio-suspensions based membranes are fabricated using a microfiber cloth soaked with a mixture of honey, turmeric powder and carbonyl iron microparticles. Plane capacitors are manufactured by introducing the membranes between two parallel Copper plates. The electrical conductivity and the relative dielectric permittivity of the membranes are measured in a static magnetic field superimposed on an electric field with fixed frequency. The results show that the membranes can be used for fabrication of devices which require a controlled release of the bio-active components found in honey and TP, by fixing the value of magnetic field density.

Effect of milk-honey mixture on the sleep quality of coronary patients: A clinical trial study

Admission of patients in coronary care units can lead to sleep disorders due to advanced monitoring and interventions. Inappropriate sleep quality in cardiac patients may be influenced by their health status. So, this study was performed to detect the effect of Milk-honey mixture on sleep status of acute coronary syndrome patients in the coronary care unit. A clinical trial study (registered under IRCT.ir with identifier no. IRCT201309285134N7) was conducted with 68 hospitalized patients with the acute coronary syndrome in the coronary care unit of a referral hospital in Semnan, Iran. After hospitalization of patients and selected eligible patients, sleep status of them was measured by Richards-Campbell Sleep Questionnaire in range of 0 to 100 score. Then patients were divided into the intervention and control groups randomly. Patients in the intervention group were received milk-honey mixture twice a day for three days. The control group patients were received routine care. In the third day, sleep quality of patients in the two groups was measured again. Finally, the data were analyzed by descriptive and inferential statistics. The mean and standard deviation of patients' age was 63.12±32.63. There was no significant difference in sleep scores on the first day of admission between the two groups (P=0.914). But, on the third day of admission, there was a significant difference in sleep scores between the intervention and the control groups (P=0.001). The mixture of milk and honey improves the sleep status of patients. So, it can be considered as an effective and affordable intervention to enhance the sleep quality of patients with the acute coronary syndrome in coronary care units.

Long-term effects of honey on cardiovascular parameters and anthropometric measurements of postmenopausal women

ObjectiveTo investigate the long-term effects of Tualang Honey versus Honey Cocktail (mixture of honey, bee bread, and royal jelly) on cardiovascular markers and anthropometric measurements of postmenopausal women. MethodsWe conducted a randomised, double blinded, two-armed parallel study comparing 20 g/day of Tualang Honey versus 20 g/day Honey Cocktail among postmenopausal women aged 45–65 years. The cardiovascular parameters and anthropometrics measurements were assessed at baseline, 6 months, and 12 months of the intervention. Results100 subjects were successfully randomised into the groups. There was a significant decrease in the diastolic blood pressure from 77.92 mmHg at baseline to 73.45 mmHg at 12 months (F-statistic = 2.55, p-value = 0.047) in the Tualang Honey group compared to Honey Cocktail. There was also a significant decrease in the fasting blood sugar from 6.11 mmol/L at baseline to 5.71 mmol/L at 12 months (F-statistic = 4.03, p-value = 0.021) in the Tualang Honey group compared to the Honey Cocktail group. The body mass index remained unchanged at 27 kg/m2 (F-statistic = 1.60, p-value = 0.010) throughout 12 months of the intervention in the Honey Cocktail group. ConclusionSubjects who received Honey Cocktail showed remarkable effects on body mass index. However, Tualang Honey supplementation showed superior effect in lowering diastolic blood pressure and fasting blood sugar compared to Honey Cocktail. Further studies are required to ascertain the underlying mechanism(s) of Tualang Honey and Honey Cocktail on each observed parameter.

WOUND DRESSINGS UPLOADED WITH MYRTLE BERRIES EXTRACT AND NIGELLA SATIVA HONEY

Objective: Wound dressings are frequently developed by introducing new products to target different aspects of the wound healing process. Many medicated dressings incorporated with natural extracts and chemicals have been developed. Chronic wounds could be invaded by many bacteria and Pseudomonas aeruginosa and Staphylococcus aureus are the most common. S. aureus and P. aeruginosa are usually detected in the higher layer of wounds or in the deepest region of wound bed, respectively. They can express many virulence factors affecting wound healing process and leading to severe infections and antibiotic resistance. Methods: Starch based impregnated gauze containing either N. sativa honey, myrtle berries hydro-alcoholic extract or a combination were prepared. There efficacy against both P. aeruginosa and S. aureus isolated from chronic wounds. Results: N. sativa honey mixture was the most potent against P. aeruginosa with an inhibition zone diameter of 18.1±0.3 mm, while the myrtle berries hydro-alcoholic extract mixture was the most potent against S. aureus with an inhibition zone diameter of 18.4±0.5 mm. The prepared impregnated gauzes deliver a moist environment that helps wounds epithelialize more rapidly. Conclusion: In conclusion, honey and myrtle berries hydro-alcoholic extract provide antibacterial and anti-inflammatory properties that will accelerate the healing process of wounds. Peer Review History: Received 14 April 2018; Revised 25 April; Accepted 8 May, Available online 15 May 2018 UJPR follows the most transparent and toughest ‘Advanced OPEN peer review’ system. The identity of the authors and, reviewers will be known to each other. This transparent process will help to eradicate any possible malicious/purposeful interference by any person (publishing staff, reviewer, editor, author, etc) during peer review. As a result of this unique system, all reviewers will get their due recognition and respect, once their names are published in the papers. We expect that, by publishing peer review reports with published papers, will be helpful to many authors for drafting their article according to the specifications. Auhors will remove any error of their article and they will improve their article(s) according to the previous reports displayed with published article(s). The main purpose of it is ‘to improve the quality of a candidate manuscript’. Our reviewers check the ‘strength and weakness of a manuscript honestly’. There will increase in the perfection, and transparency. Received file: Reviewer's Comments: Average Peer review marks at initial stage: 6.0/10 Average Peer review marks at publication stage: 7.5/10 Reviewer(s) detail: Prof. Dr. Husniye Kayalar, Ege University, Turkey, husniyekayalar@gmail.com Prof. Dr. Ali Gamal Ahmed Al-kaf, Sana'a university, Yemen, alialkaf21@gmail.com Similar Articles: COMPARISION OF ANTIDYSLIPIEMIC POTENTIAL OF 80 MILLIGRAMS OF FENOFIBRATED WITH 8 GRAMS OF NIGELLA SATIVA SEEDS DAILY

Ancient Alchemy in the Classroom: A Honey-Based, Deflagrating Pyrotechnic

A simple, honey-based pyrotechnic demonstration is presented. The demonstration has been derived from alchemical writings and highlights the importance of alchemical preparations on the development of gunpowder, chemistry, and the scientific method. The demonstration involves the combustion of mixtures of honey, potassium nitrate, and sulfur which were observed to burn with brilliant flame, heat, smoke, and sound. The combustion was rapid, visually attractive, and surprising to chemist and nonspecialist viewer alike.

English

A comparative study was conducted from November 2015 to May 2016 with the objective of investigating the beneficial effects of the mixture of cod liver oil and honey (group 1) comparing with routine treatment (group 2), combination of chlorhexidine (0.3%) and cetrimide (3%) in healing of contaminated old wounds in donkeys at Bahir Dar, North western Ethiopia. Out of 18 donkeys, 12 (6 male and 6 female) were treated with mixture of cod liver oil and honey and 6 donkeys (3 male and 3 female) were routinely treated. At the 35th day of treatment in group 1, the areas of the wounds were markedly decreased from 4.2% to 66.7% and in group 2 from 66.7% to 85.7% out of 100% of the initial area. The treatment outcome between group 1 and group 2 were significantly different (p<0.05).In group 1, no swelling and hyperemia of perilesional skin appearance, no inflammatory exudate, reduced wound area and short time to clinical healing of wound were recorded after treatment. This study also demonstrated that difference in wound healing process between sex groups, in which wound healing in male was significantly (p<0.05) faster than female. Mixture of cod liver oil and honey is beneficial in treatment of old traumatized wounds in the donkeys. This effect was primarily mediated by formation of healthy mature scars, clinical healing in short period of time. The owners, institutions or organization working with donkeys and governments may use this mixture for treating old traumatized wounds. Key words: Cod liver oil, donkey, healing, honey, wound.

Acute Modulatory Effects of Apple Cider Vinegar, Garlic, Ginger, Lemon and Honey Mixture, with and Without Exercise on Postprandial Glycemia in Non-Diabetic Females

Postprandial hyperglycemia is independently related to cardiovascular disease. Garlic, ginger, lemon, honey and apple cider vinegar are known to have anti-glycemic properties. However, the effectiveness of combination of these natural products on reducing postprandial glycemia is uncertain. The aim of the present study was to investigate the glucoselowering effect of a novel mixture consisting of apple cider vinegar, garlic, ginger, lemon, and honey; alone and in combination with exercise in response to a high-carbohydrate meal in non-diabetic individuals. Ten, female subjects (mean age: 25 ± 2.67 years, mean BMI: 22.6 ± 3.5 kg/m2 ) participated in this randomised, cross-over intervention consisting of four trials: control (CON), mixture only (MIX), exercise only (EX), and exercise + mixture (EX-MIX). All trials involved consumption of a high-carbohydrate breakfast, then followed by rest in CON, consumption of natural product mixture in MIX, brisk-walking exercise in EX, and combination of mixture and exercise in EX-MIX. Blood glucose was measured at fasting, and at 30, 60, 90, 120 minutes post meal. Postprandial glucose response was calculated as area under the glucose curve. Two-way repeated measures ANOVA showed a significant group and time interaction (p < 0.001). Compared to CON, postprandial glucose responses were 8%, 13% and 15% lower in MIX (p = 0.049), EX (p = 0.001) and EX-MIX (p = 0.005) respectively. Postprandial glucose was 8% lower in EX-MIX compared to MIX (p = 0.002). In conclusion, consuming natural product mixture containing garlic, ginger, lemon, honey and apple cider vinegar reduced postprandial glycemia to a certain extent, however, combining mixture with exercise produced a greater attenuation effect compared to consuming mixture alone. This finding is indicative of a potential benefit of the novel mixture as a complementary management of hyperglycemia in high-risk individuals. DOI : http://dx.doi.org./10.17576/JSKM-2018-15

Acute Modulatory Effects of Apple Cider Vinegar, Garlic, Ginger, Lemon and Honey Mixture, with and Without Exercise on Postprandial Glycemia in Non-Diabetic Females

Postprandial hyperglycemia is independently related to cardiovascular disease. Garlic, ginger, lemon, honey and apple cider vinegar are known to have anti-glycemic properties. However, the effectiveness of combination of these natural products on reducing postprandial glycemia is uncertain. The aim of the present study was to investigate the glucoselowering effect of a novel mixture consisting of apple cider vinegar, garlic, ginger, lemon, and honey; alone and in combination with exercise in response to a high-carbohydrate meal in non-diabetic individuals. Ten, female subjects (mean age: 25 ± 2.67 years, mean BMI: 22.6 ± 3.5 kg/m2 ) participated in this randomised, cross-over intervention consisting of four trials: control (CON), mixture only (MIX), exercise only (EX), and exercise + mixture (EX-MIX). All trials involved consumption of a high-carbohydrate breakfast, then followed by rest in CON, consumption of natural product mixture in MIX, brisk-walking exercise in EX, and combination of mixture and exercise in EX-MIX. Blood glucose was measured at fasting, and at 30, 60, 90, 120 minutes post meal. Postprandial glucose response was calculated as area under the glucose curve. Two-way repeated measures ANOVA showed a significant group and time interaction (p &lt; 0.001). Compared to CON, postprandial glucose responses were 8%, 13% and 15% lower in MIX (p = 0.049), EX (p = 0.001) and EX-MIX (p = 0.005) respectively. Postprandial glucose was 8% lower in EX-MIX compared to MIX (p = 0.002). In conclusion, consuming natural product mixture containing garlic, ginger, lemon, honey and apple cider vinegar reduced postprandial glycemia to a certain extent, however, combining mixture with exercise produced a greater attenuation effect compared to consuming mixture alone. This finding is indicative of a potential benefit of the novel mixture as a complementary management of hyperglycemia in high-risk individuals. DOI : http://dx.doi.org./10.17576/JSKM-2018-15

Antibacterial Properties of Mixture Honey and Garlic (Allium sativum) Extracts Against Respiratory Tract Infection Causing Bacteria

In Ethiopia, different local communities use mixture of honey and garlic to treat coughing and other respiratory tract infections by traditional methods. Objective of the present study was to assess the antibacterial properties of mixture of honey and garlic extract against respiratory tract infection causing bacteria. The antibacterial activity of mixture of garlic extract and honey was evaluated by methods such as agar well diffusion method to observe zone of inhibition around the well as well as broth dilution method to evaluate the minimum inhibitory concentration of the extracts against the tested organisms. Five respiratory tract infection causing bacteria such as Pseudomonas aeruginosa, Streptococcus pneumoniae, Klebsiella pneumoniae, Haemophilus influenza and Staphylococcus aureus were included in the study. Chloramphenicol was used as standard antibiotics. Mean inhibition zones of mixture of garlic extract and honey was significantly (P 0.05) greater than honey alone against the tested pathogens. The range of zone of inhibitions of mixture of garlic and honey against the tested bacteria was between 25 to 31 mm whereas the range of inhibition zone of chloramphenicol was from 9 to 30 mm. The inhibition capacity of mixture of garlic extract and honey was greater than the commercial antibiotics such as Co-trimoxazole, Cefoxitin and Erythromycin. Finally it may be possible to conclude that, mixture garlic extract and honey has the capacity to treat respiratory tract infection causing bacteria.

Corrigendum to "Inhibitory Effect of a French Maritime Pine Bark Extract-Based Nutritional Supplement on TNF-α-Induced Inflammation and Oxidative Stress in Human Coronary Artery Endothelial Cells".

[This corrects the article DOI: 10.1155/2015/260530.].

Determination of sildenafil mixed into herbal honey mixture by ultra-performance liquid chromatography-quadrupole time of flight mass spectrometry

Determination of sildenafil mixed into herbal honey mixture by ultra-performance liquid chromatography-quadrupole time of flight mass spectrometry

Detection of Korean Native Honey and European Honey by Using Duplex Polymerase Chain Reaction and Immunochromatographic Assay.

Korean native honey (KNH) is much more expensive than European honey (EH) in Korea, because KNH is a favored honey which is produced less than EH. Food fraud of KNH has drawn attention of the government office concerned, which is in need of a method to differentiate between KNH and EH which are produced by the Asiatic honeybee, Apis cerana and the European honeybee, Apis mellifera, respectively. A method to discriminate KNH and EH was established by using duplex polymerase chain reaction (PCR) in this study. Immunochromatographic assay (IC) was examined to analyze the duplex PCR product. The DNA sequences of primers for the duplex PCR were determined by comparing cytochrome C oxidase genes of the two honey bee species. Chelex resin method was more efficient in extracting genomic DNA from honey than the other two procedures of commercial kits. The duplex PCR amplifying DNA of 133 bp were more sensitive than that amplifying DNA of 206 bp in detecting EH in the honey mixture of KNH and EH. Agarose gel electrophoresis and IC detected the DNA of 133 bp at the ratios of down to 1% and 5% EH in the honey mixture, respectively and also revealed that several KNH products distributed by internet shopping sites were actually EH. In conclusion, the duplex PCR with subsequent IC could also discriminate between KNH and EH and save time and labor.

Using Goat's Milk, Barley Flour, Honey, and Probiotic to Manufacture of Functional Dairy Product.

Stirred yogurt manufactured using probiotic culture which usually called Rayeb milk in the Middle East region is one of the most important functional fermented milk products. To increase the health and functionality properties to this product, some ingredients like fruits, cereal, and whey protein are used in production. This study was carried out to prepare functional Rayeb milk from goat's milk, barley flour (15%) and honey (4%) mixtures using ABT culture. Also, vanilla and cocoa powder were used as flavorings. Adding barley flour and honey to goat's milk increased curd tension and water-holding capacity and decreased coagulation time and susceptibility to syneresis. The values of carbohydrate, total solids, dietary fiber, ash, total protein, water soluble nitrogen, total volatile fatty acids, unsaturated fatty acids, oleic, linoleic, α-linolenic acids, and antioxidant activity were higher in Rayeb milk supplemented with barley flour and honey than control. The viabilities of Lactobacillus acidophilus and Bifidobacterium lactis Bb12 (Chr. Hansen's Lab A/S) increased in fortified Rayeb milk. The recommended level of 107cfug-1 of bifidobacteria as a probiotic was exceeded for these samples. Addition of vanilla (0.1%) or cocoa powder (0.5%) improved the sensory properties of fortified Rayeb milk.

Topical Application to Mixture of Honey with Cod Liver Oil as a Novel Therapy to Treat Contaminated Skin Wounds in Rabbits Model

Contaminated wounds are common in all animals and human being; their treatments may complicated and need for prolong duration, therefore the current study aimed to investigate an alternative way to treat the contaminated wounds by using natural compounds that accelerate wounds healing; these study achieved on 30 local rabbits that exposed to surgical excision and contaminated by Staphylococcus aureus then divided into 5 groups in which 6 animals of each and treated for 14 days as the following: the first group treated with honey, second group treated with cod liver oil, third group treated with mixture of honey and cod liver oil, fourth group treated with fucidin while the fifth group contaminated with bacteria only. The results showed moderate (1.55 ± 0.11) wound contraction and healing in first group, while the second group showed (1.77 ± 0.10) was delayed in wound contraction and healing, the third group showed (1.0±0.13) which regarded the excellent and optimal wound contraction and healing, the fourth group showed (1.77 ± 0.12) which delayed wound healing and contraction, finally the fifth group showed(3.07 ± 0.11) in which no signs of wound contraction and healing. In conclusion, the using of mixture of natural compounds like honey and cod liver oil may accelerate wound contraction and healing and keep the wounds sterile.

Water activity of fresh bee pollen and mixtures of bee pollen-honey of different botanical origin

A mixture of bee pollen and honey could represent a complete food supplement for human diet. In this study, for three bee pollen-honey mixtures ratios at two storage times (0 and 90 days) at room temperature, water activity (aw) were investigated. For the mixtures were employed Castanea and Eucalyptus pollen species, and acacia, chestnut and “beach” honeys. In the mixtures, Castanea and Eucalyptus pollen showed a different aw trend in relation to pollen concentration and to storage time. In Castanea-honeys mixtures and in Eucalyptus-honey mixtures (only at time 0) aw values were higher than each component of the corresponding mixtures. In Eucalyptus-honeys mixtures (only at time 90) aw values were lower than each component. This investigation highlights that honey, bee-pollen and their mixtures, stored at room temperature, could have a little change in their aw content, in time. Results shows that aw values of bee pollen mixed with honey were all lower than 0.7, although bee pollen-honey mixtures were stored at room temperature instead at freezing temperature (−15 °C) for 90 days.

The Effect of a Mixture of Royal Jelly and Honey on Hematological Parameters in Maximum Weight Training Athletes

The Effect of a Mixture of Royal Jelly and Honey on Hematological Parameters in Maximum Weight Training Athletes

Tingkat kesukaan lebah madu Apis Mellifera L. terhadap pakan tambahan campuran madu mengkudu

Feeding supplementary food containing nony fruit juice was tested on honeybee colonies in honey producing . The aims of this research were (1) to determine the preference level of honeybees to the supplementary food containing honey and nony mixture, (2) to identify the organoleptic properties of the produced honeyessence of nony, (3) to determine fiber content of produced honey-essence of nony, and (4) to identify the colours of honey produced. The design used in the experiment was Latin Square Design. There were four treatments namely each concentration : A (0%) as control, B (12,5%), C (25%) dan D (37,5%) in dilution of supplementary food an amount of 600 grams wich consist of nony fruit juice and water. Each composition of dilution were A (300, 0, 300), B (225, 75, 300), C (150, 150, 300) dan D (75, 225, 300) . Every one replication was done for six days with six day interval. The result were as follows: The higher concentration of nony juice in the food suplement the smaller food were taken. The differences in the olour, the flavour and the taste of the artificial honey didn’ depend on the amount of the food suplement taken honey bees, but depend on nony fruits juice concentration in the honey produced. The higher concentration of nony fruit juice in the artificial honey produced the darken in colour, sour in taste and the weaken in flavour. Feeding with food suplement containing nony juice increases the fiber content in the honey.