Reiner-Rivlin nanofluid flow between two disks exhibiting homogenous-heterogeneous reactions in a porous media with slip effects is appraised in this study. The envisioned unique model is supported by the surface catalyzed reaction that triggers the chemical reaction in the minimum possible time. Considering the entropy generation allows gauging the energy loss and thermal performance during the process. The similarity transformations are affianced to get the ordinary differential equations system with high nonlinearity and are handled by numerical technique bvp4c by MATLAB software. The outcomes in graphical form portraying the relationship of the protuberant factors along with associated profiles are presented. The fallouts disclosed that the disk’s torque is on the decline for high values of wall roughness. Another interesting outcome unveiled that both axial and radial velocities are weakened for the high estimates of wall roughness. To sum up the justification of the proposed model, a comparison table in a limiting case is also added.