Homeopathic Research Articles

Individualized homeopathic medicines in preventing the progression from pre-diabetes to diabetes: A double-blind, randomized, placebo-controlled, parallel-arm trial

ContextPre-diabetes is a significant public health problem worldwide. India has a very high rate of progression from pre-diabetes to diabetes, 75–78 per thousand persons per year. ObjectiveTo study the efficacy of individualized homeopathic medicinal products (HMPs) against placebos in preventing the progression from pre-diabetes to diabetes. DesignSix-month, double-blind, randomized (1:1), two parallel arms, placebo-controlled trial. SettingOutpatient departments of D. N. De Homoeopathic Medical College and Hospital, Kolkata, West Bengal, India. PatientsSixty participants with pre-diabetes. InterventionsVerum: HMPs plus yoga therapy (YT; n = 30); control: identical-looking placebos plus YT (n = 30). Main outcome measuresThe primary efficacy endpoint was the proportion of participants progressing from pre-diabetes to diabetes, measured after three and six months. Secondary outcomes comprised of fasting blood glucose (FBS), oral glucose tolerance test (OGTT), glycated hemoglobin percentage (HbA1c%), lipid profile, liver enzymes (alanine transaminase, aspartate transaminase), urea and creatinine, and Measure Yourself Medical Outcome Profile version 2 (MYMOP-2); all measured after 3 and 6 months. ResultsThe proportion of participants converted from pre-diabetics to diabetics (n/N; n = diabetics, N = prediabetics) was significantly less in the verum group than control: HbA1C% (month 3: verum – 2/30 versus control – 11/30, p = 0.003; month 6: 3/30 vs. 2/30, p = 0.008), OGTT (month 3: 0/30 vs. 8/30, p = 0.015; month 6: 0/30 vs. 1/30, p = 0.008), but not according to FBS (month 3: 1/30 vs. 1/30, p = 0.779; month 6: 1/30 vs. 3/30, p = 0.469). Several secondary outcomes also revealed significant improvements in the verum group than in placebo: HbA1C% (p < 0.001), OGTT (p = 0.001), serum ALT (p = 0.031), creatinine (p = 0.012), and MYMOP-2 profile scores (p < 0.001). Sulphur, Bryonia alba, and Thuja occidentalis were the most frequently indicated medicines. Thus, HMPs outperformed placebos by successfully preventing the progression of pre-diabetes to diabetes. Trial registrationClinical Trials Registry – India CTRI/2022/04/042,026; UTN: U1111–1277–0021

Homeopathic Medicinal Products and Importance in Diabetes

Background: Diabetes is a condition that happens when your blood sugar (glucose) is too high. It develops when your pancreas doesn’t make enough insulin or any at all, or when your body isn’t responding to the effects of insulin properly. Diabetes affects people of all ages. Most forms of diabetes are chronic (lifelong), and all forms are manageable with medications and/or lifestyle changes. So many health problems can develop in diabetic people, like heart diseases, kidney diseases, eye problems, etc. Diabetes mellitus is a chronic disease. A qualified homeopathic doctor needs to be consulted for the selection of the right medicine and its potency. Objective: There are many allopathic medicines available for the treatment of diabetes, but they have lots of side effects. The main objective of this study is to find out the appropriate homeopathic medicines for the treatment of diabetes. Methods: A literature search was conducted on the databases, namely Science Direct and PubMed, with the help of different keywords such as &amp;quot;homeopathic medicine treatment of diabetes.&amp;quot; The search was customized by applying the appropriate filters so as to get the most relevant articles to meet the objective of this review article. Result: There are different research and review papers based on the homeopathic medicine treatment of diabetes and the activity of new drug molecules. Conclusion: On the basis of our study, we found that some treatments approach homeopathic medicines for the treatment of diabetes and suggested that if we used homeopathic medicine to reduce the side effects of allopathic medicines.

Repurposing the anti-angiogenic activity of homoeopathic medicines by employing Chick embryo model- An In-Ovo Study

Background: Homoeopathic medicines have the potential in treatment of patients suffering from cancers, Diabetic Retinopathy, and hemorrhagic disorders wherein anti- angiogenesis plays a vital role. Homoeopathic medicines have been used to treat haemorrhagic disorders. For example, Hamamelis is used in haemorrhages, varicose veins and in venous congestion. Thalaspi bursa is used in flabby condition of uterus, haemorrhagic conditions of uterine fibroid. This been said, their mechanism of action remains unknown. Therefore, this study was intended to establish angiogenic/anti-angiogenic effect of the selected homoeopathic medicines employing chick embryo model.&#x0D; Objective:&#x0D; &#x0D; To study the anti-angiogenic properties of selected homoeopathic medicines employing YSM assay in the chick embryo model.&#x0D; To test the toxicity of selected homoeopathic medicines through Chick embryo model.&#x0D; &#x0D; Materials and Method: Yolk Sac Membrane is widely utilized as an in vivo system to study angiogenesis and anti-angiogenesis. The images for all YSMs were captured and were analyzed for angiogenic/anti-angiogenic effect.&#x0D; Results: Significant anti-angiogenic effects were observed in 10% concentrations of Hamamelis200cH, Thalaspi bursa 200cH and Thalaspi bursa 1M. Reduction of vessel density and total vessel network length, total branching points, total nets and total segment symbolizes that these medicines have anti-angiogenic potential and so they help in treating menstrual disorders, which is followed with cramps and discharge of clots.&#x0D; Conclusion: The mechanism of action of selected homoeopathic medicines as anti- angiogenic agent is proved which can be used to combat various diseases like haemorrhages, varicose veins, in venous congestion and problems related to haemorrhagic disorders. This will further help to study the action of these Homoeopathic medicines as potential line of treatment in patients suffering from cancers, Diabetic Retinopathy, hemorrhagic disorders wherein anti- angiogenesis plays a vital role.

A Study to Evaluate the Anti Bacterial Activity of Squilla Maritima Against Streptococcus Pneumonia in - Vitro

This study aims to evaluate the antibacterial properties of Squilla maritima, a homoeopathic medicine, against Streptococcus pneumonia, a common pathogen in the human upper respiratory tract. The Agar Well-Diffusion test will be used to screen the bacteria at 30C and 200C potencies. Result: Squilla maritime 30C (0.8±0.1), 200C (0.6±0.1) cm. showed inhibitory activity against Streptococcus pneumonia by Agar well-diffusion assay. Squilla maritima 30 showed maximum Growth inhibitory zone (GIZ) against Streptococcus pneumonia. But Vehicle control (Dispensing alcohol or ethanol 90%) showed 10mm of Growth inhibitory zone which is more than squilla 30C. Conclusion: This experiment showed that the homoeopathic medicine Squilla maritima has antibacterial property against Streptococcus pneumonia which is less effective than dispensing alcohol.

Increasing Blood Oxygen Saturation following 6 minutes’ Walk Test in Healthy Human Volunteers with Coca erythroxylon 6CH and Vanadium metallicum 6CH: A Double-blind, Randomized, Placebo-controlled Pilot Trial

Abstract Background: Oxygen saturation (SpO2) is an essential component during patient care and management because a variety of acute negative consequences on specific organs and systems can result from hypoxemia. Aim and Objective: The effects of two homeopathic medicines, Coca erythroxylon 6CH and Vanadium metallicum 6CH, were explored against placebos on blood SpO2 following a 6-min walk test (6MWT) in apparently healthy human volunteers after 3 days of intervention. Subjects and Methods: A 3-day, randomized (1:1:1), double-blind, placebo-controlled pilot trial was conducted on 60 healthy human volunteers. Participants were randomized to Coca erythroxylon (n = 20), Vanadium metallicum (n = 20), and identical-looking placebos (n = 20). Blood SpO2% (primary), peak expiratory flow (PEF; mL), and breath holding timing (s) were measured at baseline once preintervention and postintervention and again before and after a 6MWT. Interventions were administered 4 times a day for 3 consecutive days. Group differences were estimated using a one-way analysis of variance. Significance levels were set at P &lt; 0.05 two-tailed. Results: Statistically significant differences in pre- and postintervention mean changes were observed in blood SpO2% in the Coca erythroxylon group in comparison with the others (F 2,57 = 3.815, P = 0.028); however, no such significant differences could be observed in PEF and breath holding time. No adverse events were reported. Conclusion: Coca erythroxylon significantly increased blood SpO2% following a 6MWT in healthy human volunteers. It is necessary to conduct definitive trials to validate the findings. Trial Registration: CTRI/2022/08/044810; UTN: U1111-1281-3263.

A Study to Evaluate the Antibacterial Activity of Homoeopathic Medicine Myristica Sebifera Mercurius Iodatus Rubrum Hamamelis Virginica Against Staphylococcus Aureus - in Vitro

Staphylococcus aureus is a Gram-positive, non-moving cocci found in grape-like clusters in the upper respiratory tract and skin. It is a member of the Bacillota and can grow without oxygen. Although it acts commensally, it can also become an opportunistic pathogen, causing skin infections, respiratory infections, and food poisoning. In 1880, Scottish surgeon Alexander Ogston discovered that Staphylococcus can cause wound infections after observing bacteria in pus from surgical abscesses. S. aureus is a common bacteria that can be found on the skin of the host, but most of its carriage occurs through the nasal passages and ears. The purpose of this study is to assess the antibacterial efficacy of the homoeopathic remedies Hamamelis virginica, Myristica sebifera, and Mercurius iodatus ruber against Staphylococcus aureus.As a result, the Agar Well-Diffusion assay is employed to screen the bacteria at 30C, 200C, and 1M potencies. Findings: Myristica sebifera 30C(11) mm, 200C (9 ) mm, 1M (10) mm; Mercurius iodatus ruber 30C (6 ) mm, 200C ( 8 ) mm, 1M ( 7) mm; Hamamelis virginica 30C(3 ) mm, 200C( 4) mm, 1M ( 5) mm; Mercurius sebifera in 1M showed maximum Growth inhibitory zone (GIZ) against Staphylococcus aureus following comparison with Vehicle control (dispensing alcohol or ethanol 90%) and Positive control (Amoxyclavatum).

Case report: use of conium maculatum as an aid to lower limb pain and paresia in type 1 neurofibromatosis in treatment of optic pathway glioma

Neurofibromatosis type 1 is one of the most common autosomal dominant disorders, presenting a higher risk of developing plexiform tumors and neurofibromas, whose conventional treatment, based on surgical, chemotherapy or radiotherapy procedures, still has limitations. Comorbidities such as neuralgic, muscular or paretic and paralytic pain may occur depending on the tumor situation or the plexiform neurofibroma. Given the difficult approach to these patients, and with the aim of expanding research and homeopathic knowledge about these cases, we present a case of pain associated with lumbosacral plexiform neurofibroma during oncological treatment for Glioma of the Optic Pathways, without surgical indication, but with difficult pain. control, even when using analgesics and antidepressants. Chemotherapy oncological treatment, due to crises and maintenance of pain, had been postponed. As an aid in controlling the symptoms, considering the ascending paretic pain syndrome of the left lower limb, the homeopathic medicine Conium maculatum was used as a complementary aid to the therapy. The patient's symptoms improved and she was able to continue with the chemotherapy treatment indicated, with a progressive reduction in the use of analgesics until they were discontinued.

Role of Homoeopathic Medicines in Dermatophytosis Infections of Children Between the Age Group of 5-18 Years

Role of Homoeopathic Medicines in Dermatophytosis Infections of Children Between the Age Group of 5-18 Years

A Study to Evaluate the Antibacterial Activity of Homoeopathic Medicine Hydrocotyle Asiatica Mother Tincture 30th Potency and 200th Potency Against Staphylococcus Aureus – In Vitro

A Study to Evaluate the Antibacterial Activity of Homoeopathic Medicine Hydrocotyle Asiatica Mother Tincture 30th Potency and 200th Potency Against Staphylococcus Aureus – In Vitro

ANALYSIS OF CONSUMER PREFERENCES AND THEIR INFLUENCE ON THE USE OF HOMEOPATHIC MEDICINES IN THE COMPLEX TREATMENT OF ACUTE RESPIRATORY VIRAL INFECTIONS

This article is devoted to the analysis of consumer preferences in the context of treatment of acute respiratory viral infections (ARVI) using homeopathic medicines. The study covers various aspects such as patients' main motivations for choosing homeopathy, their level of satisfaction with the results of treatment, and factors influencing the use of homeopathic remedies in complex therapy. The authors of the article review data from social surveys conducted on Google Forms portal, medical research, and literature reviews to provide a comprehensive overview of current trends in the use of homeopathic remedies in the treatment of acute respiratory infections. Special attention is paid to the influence of sociocultural and educational factors on patients' decision-making regarding treatment choices. The results of the study may be useful for health professionals, pharmacists and public health organizations, helping to better understand consumer preferences for homeopathy and to develop individualized approaches to the treatment of acute respiratory infections. The aim of the study is to analyse consumer preferences in the use of homeopathic medicines in the complex treatment of acute respiratory viral infections. Materials: Questionnaires and Surveys: Development of structured questionnaires to collect information from patients about their preferences, motivations and experiences of using homeopathic medicines for ARVI. The survey was conducted anonymously on Google Forms platform, which allowed systematisation of the data obtained. Internet resources: Analysis of discussions and reviews on medical forums and social networks related to homeopathy and treatment of acute respiratory infections. Methods: Statistical analysis: Processing data from questionnaires using statistical techniques such as frequency and correlation analyses. Qualified interviews: Conducting interviews with patients, doctors to gain a deeper understanding of motivations and experiences of using homeopathic medicines. Systematic literature review: Examining existing scientific articles and publications related to homeopathy and ARVI to obtain additional data and context. Comparative analysis: Comparison of questionnaire results with literature review and interviews to identify trends and influence of consumer preferences on the use of homeopathic medicines. Results. The study found that homeopathic medicines have the potential to be in demand in the comprehensive treatment of acute respiratory infections. Scope of the findings: the results of the study may be useful for health professionals, pharmacists and public health organisations, helping to better understand consumer preferences for homeopathy and to develop individualised approaches to the treatment of ARVI.

Homeopathic Pyrogenium Ointment as Adjuvant in Treatment of Traumatic and Infected Myiasis by Cochliomyia Hominivorax (Diptera: Calliphoridae) in Sheep: A Case Series.

The blowfly Cochliomyia hominivorax (Diptera: Calliphoridae) causes traumatic myiasis in farm animals, with deeply embedded larvae that lead to serious tissue damage and sometimes death. Treating this form of myiasis is difficult, often resulting in poor outcomes. As a homeopathic preparation that can mimic traumatic myiasis symptoms, Pyrogenium could potentially supplement treatment. This study aimed to describe the adjuvant effect that a Pyrogenium ointment might have in the treatment of sheep with traumatic myiasis. The study reports a homeopathic adjuvant treatment with Pyrogenium 12cH ointment in six sheep with traumatic and infected myiasis. Daily clinical examinations were performed to monitor the evolution of the health of animals. Pyrogenium 12cH ointment was applied topically on the wounds, after cleaning and mechanical removal of the larvae from the lesion. Blood samples were collected for blood counts, and wound exudate samples were obtained for bacteriological examination before and after wound treatment. The ointment of Pyrogenium 12cH limited the development of parasitic larvae and was associated with the repair of tissue losses resulting from the myiases and with subsequent wound healing, together with control of fever and local inflammation. Homeopathic Pyrogenium 12cH, formulated as an ointment, may be a useful new and adjuvant therapeutic option for treating traumatic and infected myiasis in animals.

Tinea cruris managed with a single dose of individualised homoeopathic medicine: A case report

Tinea cruris managed with a single dose of individualised homoeopathic medicine: A case report

Obstinate chronic venous ulcer treated with the homoeopathic medicine Silicea: A case report

Obstinate chronic venous ulcer treated with the homoeopathic medicine Silicea: A case report

Homoeopathic treatment of a child with internet gaming disorder and atopic dermatitis: A case report

Homoeopathic treatment of a child with internet gaming disorder and atopic dermatitis: A case report

Homeopathy for Chronic Non-specific Low Back Pain: Study Protocol for a Randomized, Double-Blind, Crossover, Placebo-Controlled Clinical Trial Investigating the Efficacy of the Biotherapic Lumbar Vertebra (The BIOVERT Trial).

Chronic non-specific low back pain (CNSLBP) lacks identifiable anatomical pathology and effective pharmacological treatment. Alternative approaches in homeopathy, specifically clinical homeopathy, utilize ultra-diluted (potentized) biological products. In Brazil, standardized biotherapics from sheep tissues, particularly fifty-millesimal (LM) potencies of sheep Lumbar Vertebra, have shown promise in alleviating CNSLBP. Our objective is to present the study protocol of a clinical trial that will assess the efficacy and safety of the biotherapic Lumbar Vertebra LM2 in the short-term management of CNSLBP and to estimate its therapeutic duration. A randomized, double-blind, crossover, placebo-controlled clinical trial spanning 8 weeks per participant was designed. Participants will include 120 individuals (aged 20 to 60 years) with clinically diagnosed CNSLBP by the study's physiotherapist. Exclusion criteria are radicular pain, signs of radiculopathy, specific lumbar spine disorders, pregnancy, or puerperium (up to 60 days after delivery). The medical intervention includes participants being randomly assigned to one of two treatment sequences: homeopathy-placebo or placebo-homeopathy. The treatments will consist of Lumbar Vertebra LM2 oral solution, topical cream, and indistinguishable placebos. Each treatment period will span 2 weeks, with a 4-week washout interval between them. Primary outcome is the assessment of changes in self-reported pain levels using the numeric rating scale (NRS) score, analyzed with a random effects model across both treatment periods. Secondary outcomes are assessment of changes in self-reported disability levels using the Oswestry Disability Index (ODI), analyzed with a random effects model across both treatment periods, and pain and disability variations, evaluated by the NRS score and ODI respectively, after the first and second treatment periods. Adverse events will be assessed at weeks 2 and 8. Pain medications will be used concomitantly. Adherence will be evaluated by the weight of medication returned/standard weight. The BIOVERT (Bioactive Vertebra) trial protocol is designed to investigate a homeopathic strategy for short-term CNSLBP treatment. Favorable outcomes for homeopathy could prompt subsequent studies evaluating the long-term effectiveness of LM potencies of Lumbar Vertebra for CNSLBP. UMIN Clinical Trials Registry - ID: UMIN000051957.

Exploring the Role of Homoeopathic Medicines in Eating Disorders

For those suffering from eating disorders , Homeopathy is incredibly helpful. Utilizing a carefully chosen constitutional homeopathic remedy can aid in the healing process of this illness. These medications significantly improve symptoms by acting at a profound psychological level. They restore mental equilibrium and aid in the elimination of obsessive-compulsive thoughts and anxieties that cause someone to avoid eating. These medications work well in mild to moderate situations.

LITERARY REVIEW OF KALAMEGHA (ANDROGRAPHIS PANNICULATA)WSR INDIAN AND SRI LANKAN LITERATURE

Acharyas of Ayurveda scientifically categorised various drugs under the topic of Ganas and Vargas based on guna karma and therapeutic uses. The classical text is an authentic source for drug identification, therapeutic activities and substitutes. Kalamegha is one such drug botanically identified as Andrographis panniculata, dis-tributed in the plain regions of the Indian subcontinent. This plant is widely used in Ayurveda, Siddha, homoeo-pathic, and Sri Lanka's traditional medicine systems. It is indicated in Kushta, kandu, Shopa, yakrith roga , kri-mi and jwara. Andrographoloids and Neo andrographoloids are the active principles that prevent oxidative damage and inhibit the binding of toxic metabolites to DNA. Hence used for treating anti-inflammatory, hepato-protective, anti-bacterial, anti-viral, antioxidant, anti-parasitic, anti-diarrheal and several infectious diseases rang-ing from malaria to dysentery. The study aims to explore the review literature of Kalamegha from all the medical classical texts and journals of Indian and Sri Lankan origin. And present a summary of the available records. According to references, in different geographical regions, Kalamegha is termed as Bhunimba, bunimo, kiratha thikta, desh kiratha, bin Kohomba, etc., having tikta rasa, laghu ruksha guna, ushna veerya, katu vipaka and kapha pitta hara, deepana and pachana properties. Literary review plays a vital role as it aids in the identifica-tion of the drugs and therapeutic utilities of outspread drugs in different geographic regions. Since the Kalamegh plant is widely distributed in India and Sri Lanka, an attempt was made to record the uniformity and diversities of the morphological and therapeutic utilities of the Kalmegha.

A Prospective Observational Study to Evaluate the Effectiveness of Homeopathic Intervention as an Alternative to Analgesics in Managing Cases of Arthralgia

This prospective observational study explores the effectiveness of individualized homeopathic intervention as an alternative to analgesics in managing arthralgia. Conducted over 18 months at Pandit Jawaharlal Nehru State Homoeopathic Medical College &amp; Hospital, Kanpur, U.P., the study involved 200 patients with generalized joint pain, knee joint pain, shoulder joint pain, and heel joint pain. Utilizing the law of similars, homeopathic medicines were prescribed, with Rhus toxicodendron being the most frequently recommended. The Visual Analog Scale (VAS) for pain severity demonstrated a statistically significant improvement after 6 months of treatment (mean decrease of -3.39 on VAS, p &lt; .00001). Findings suggest that individualized homeopathic treatment offers a promising alternative for arthralgia management, emphasizing the need for further research and contributing valuable insights to holistic patient care.

Homeopathic preparations to increase resistance and development of yield in bean (Phaseolus vulgaris) crops

The common bean (Phaseolus vulgaris) is an essential part people’s staple diet in Brazil as well as in some Latin American countries. The excessive use of agrochemical for pest and disease control negatively impacts human health, contaminates soil and water, harms biodiversity, and contributes to pest resistance. It is referred to a specific homeopathic preparation. In the context of homeopathy, the term "preparations" refers to homeopathic remedies that are created through a specific process of dilution and agitation. The use of highly diluted homeopathic preparations, which enhance the plants ability to resist diseases, represents a more sustainable and environmentally friendly alternative. In homeopathy, "Silicea" is used as a homeopathic remedy derived from silica which is not a silica in its natural form. The objective of this study was to evaluate the effect of Silicea terra and Phosphorus application in high dynamized dilutions, on morphometric and productive variables of common bean plants. Two experiments were carried out in a greenhouse and one experiment in the field, in a randomized block design for both situations. In greenhouse, the preparations were used in dynamizations 7, 12, 24, 36, 48 and 60CH (CH= Hahnemannian centesimal dilution order) and distilled water was used as control. In the field, the treatments were Phosphorus 48 and 60CH, Silicea terra 36 and 60CH, and distilled water as a control. In greenhouse, application of Silicea terra 36CH increased (p&lt; 0.05) shoot dry biomass weight (9.78 g) and leaf dry biomass weight (5.36 g), compared to control. In the field, Silicea terra 36CH and Phosphorus 60CH increased bean productivity in relation to the control. The results indicate that homeopathic preparations had a high potential for improving development and consequently increasing yield when applied to common bean plants.

Rapid Recovery of One-Sided Verruca Vulgaris (Common Wart) with Homoeopathic Treatment: A Case Report

Abstract Background Verruca vulgaris or common wart is a very common dermatological condition resulting from human papillomavirus infection affecting epithelial tissues of the skin and mucous membrane. Only destructive therapies are available in modern medicine for the treatment of such conditions. Case The case was reported at a health camp with warts on the right hand. The patient did not manifest many symptoms in the initial case recording, but on further skilful enquiry elicited symptoms which helped in the selection of remedy. Adequate patience and timely repetition of remedies helped to recover the lesion within 58 days of initiation of treatment. Conclusion Warts are a very common condition reporting at the clinic of homoeopathic physicians expecting a recovery in a mild manner. This case reports that such a condition can be efficiently treated rapidly by homoeopathy.