Background: This study sought to investigate the relationship between parents’ level of education and pupils’ academic performance in primary schools. Methodology: A mixed-method research approach was used in this study to generate data. Using questionnaire and interview guide tools, data was collected from the study respondents including pupils, teachers, head teachers, parents as well and the Area Education Officer. Results: Findings revealed that parents’ level of education influences pupils’ academic performance. Tool items such as parents checking books and home works (M=1.70, SD=1.042), parents assisting in doing homework (M=2.43, SD=1.355), parents reading and replying to letters from schools (M=2.01, SD=1.131) and pupils having enough time at home to study (M=1.97, SD=1.050), were found to be among major factors that determine pupils’ performance. Conclusion: Parental level of education was statistically significant towards pupils’ academic performance in Palisa District. The educational attainment of their children in both rural and national samples was easily influenced by their conducive home study environment. Recommendation: Parents are advised to pay full attention to their children’s education at home. They should make a timetable for their children regarding homework and studies. In this way, their academic performance will be improved.