Abstract The article examines the key factors influencing women’s electoral success in European Parliament (EP) elections. We present a new conceptual approach and a novel model that simultaneously incorporates trends in party characteristics, institutional and socio-economic factors and cross-country trends in women’s representation. The model provides a comprehensive analysis of the relationships between party-level and Member State-level factors and the election of women to the EP. The study is based on an original dataset of 450 observations on national political parties from all Member States, spanning four European elections from 2004 to 2019. Our results show that party characteristics such as incumbency rates, party size and ideological orientations (i.e. the party’s position on the GAL-TAN scale or its attitude towards European integration) play a key role in shaping women’s representation. This article provides novel insights into the unique features of Central and Eastern Europe, elucidating divergent patterns of women’s electoral prospects in conservative and progressive parties in Western democracies and Central and Eastern European post-communist EU Member States.