Background: Psoriasis is an immune-mediated chronic proliferative skin disorder, predominantly involves skin, nails, and joints This research was conducted to study the clinical presentation, and management of psoriasis among patients in tertiary care hospital in South India The medical records of 257 psoriasis pati Methods: ents over the past one year (from January 2022 till December 2022) were examined by the investigators. Data were collected using a semi-structured form. Total 257 patients were Results: included in this study. Majority of patients were belonging to 50 and above age group. Male predominance (63%). Most common clinical variant was chronic plaque psoriasis (65.7%) followed by palmoplantar psoriasis (15.9%). Relapse of psoriasis was seen more among patients with a history of disease exacerbation in winter and in rainy season. Co-morbidities like diabetes mellitus and complications like PsA were associated with greater disease durations among the patients. In the current study, the proporti Conclusion: on of patients with chronic plaque psoriasis was high, most likely due to delayed diagnosis, followed by palmoplantar psoriasis and scalp psoriasis. Topical steroids for psoriasis in limited areas, oral methotrexate, and phototherapy for extensive psoriasis.