The article analyses the effectiveness of the experience of organizing social control over women of commercial sex in Mykolaiv region in the 19th century. An analysis of the historical basis of the phenomenon of commercial sex was carried out, the concept, essence and content of social control over women of commercial sex were determined, the activity of state authorities in the direction of social control over women of commercial sex in the Mykolaiv region in the 19th century was analysed, and the cause-and-effect relationships of social control over the phenomenon of commercial sex in modern Ukraine. The basis of the research methodology is the principle of historicism, which made it possible to consider the phenomenon of prostitution in accordance with historical stages and events, in their interconnection and interdependence. As part of the toolkit of the proposed article, a set of methods is used, namely: theoretical - content analysis, historical-systemic and historical-typological method, as well as systematization, generalization, detection of contradictions, comparison, descriptive method; empirical - interviewing method. The authors came to the conclusion that social control can be defined as a state mechanism, the purpose of which is to maintain social order, norms of individual behaviour in society. The peculiarities of formal and informal social control over women of commercial sex in the 19th century are determined. The analysis of the activities of state authorities over women of commercial sex in the Mykolaiv region in the 19th century made it possible to investigate formal social control, for its implementation, the authorities and local managers of the Mykolaiv region established rules and laws regarding brothels, their owners, and women of commercial sex directly. Cause-and-effect relationships with social control of commercial sex in modern Ukraine were established. The analysis of the state of commercial sex in Ukraine indicated the need for social prevention, as a method of social control, over persons from the risk group.