Histological Reconstruction Research Articles

THE STRUCTURE OF FORDYCE'S DISEASE AS DEMONSTRATED BY WAX RECONSTRUCTION

In 1896, Fordyce described both clinically and histologically a disease of the lips and the mucous membrane of the oral cavity which has now become a familiar clinical picture to every dermatologist and is known as Fordyce's disease. One phase of the subject, the pathology, has remained controversial, and, although convincing demonstrations have been made by Margolies and Weidman, 1 subsequent reports 2 indicate that opinions are not yet unanimous, as will be brought out later. This fact, based on histologic reconstruction and description of the lesion, prompted further study and seems to warrant this report. At the same time, some of the work of Margolies and Weidman has been repeated. The following report deals with histologic structure alone. It is not necessary to repeat here all of the finer details involved in the controversy on the pathology of Fordyce's disease. These appear in the paper of Margolies and Weidman.