Abstract Purpose To assess the most accurate and practical technique for intraocular pressure (IOP) measurement in children and adolescents Type of the Study Cross-sectional observational Methods 90 eyes of 45 patients were included in this study. Central corneal thickness (CCT) was measured using specular microscopy. IOP was assessed by Goldman applanation tonometer (GAT), Non-contact tonometry (Air-puff), and Tono- Pen in both right and left eyes. Results The mean age of participants was 14.8 years. Mean CCT was 548.7 µm in the right eye and 549.2 µm in the left eye (P = 0.687). Mean IOP measured by GAT, Air-puff, and Tono-Pen was 11.7, 14.1, and 11.3 mmHg in the right eye, respectively, and 11.7, 14.2, and 11.5 mmHg in the left eye, respectively. Air-puff readings were significantly higher than GAT and Tono-Pen (P > 0.0001) in both the right and the left eyes. On the other hand, Tono-Pen showed no statistically significant difference from GAT measurements either in the right (P = 0.447) or the left eye (P = 1). The highest correlation with GAT was seen with the Air-puff. CCT was positively correlated with all used devices. Conclusion Tono-Pen provides the most accurate alternative for GAT. Although Air-puff offers a more accessible option for IOP measurement in adolescents, attention should be taken as it gives significantly higher measurements.
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