Aim: To identify factors affecting the digital burnout levels of nursing students during the pandemic period. Method: The descriptive and cross-sectional study was conducted with 1000 nursing students. Data of the research was collected between March-April, 2021 as online survey by using “Introductory Information Form” and “Digital Burnout Scale”. In addition to descriptive statistical analyses, Kruskal-Wallis test and Dunn-Bonferroni test were used for the comparison of non-normally distributed quantitative variables between more than two groups. Spearman correlational analysis was used for evaluating the relationships between quantitative variables. Statistical significance level was accepted as p < 0.05. Results: Regarding the Digital Burnout Scale scores of the students, average total scores were 2.70±0.92 (Min.=1-Max.=5, Median=2.67) for “Digital Aging” dimension, 3.17±1.06 (Min.=1-Max.=5, Median=3.33) for “Digital Deprivation” dimension and 2.76±0.93 (Min.=1.17-Max.=5, Median=2.67) for “Digital Exhaustion” dimension. Average total score of the overall scale was 2.83±0.86 (Min.=1.04-Max.=5, Median=2.79). Conclusions and Suggestions: Nursing students experienced high level of digital burnout during the pandemic. The year of study of students and the time they spend on digital environments affects the level of digital burnout. Measures should be taken to reduce digital burnout during the distance nursing education.