High Levels Of Pb Research Articles

Exploring the combined effect of heavy metals on accumulation efficiency of Salix alba raised on lead and cadmium contaminated soils

The present study illustrated that Salix alba can accumulate high level of Pb and Cd in different plant parts, with maximum accumulation in roots followed by stem and leaves in the order Cd > Pb > Cd + Pb. The phytoremediation evaluation factors such as bioconcentration factor (BCF) and translocation factor (TF) was higher for Cd over Pb in all plant parts, further the BCF for both Pb and Cd was maximum in root (BCF > 1) followed by stem and leaves. Higher accumulation of Cd over the Pb was observed inside the plant tissues due to Cd mimics with other elements and gets transported through respective transporters. The combined treatment of Pb and Cd affected the bioaccumulation at every treatment level suggesting the negative effect among both elements. Higher survival rate (>85%) was recorded up to 200mgPb/kg and 15mgCd/kg, while further increase in metal concentration reduced the plant efficiency to remediate contaminated soils, hence results in declined survival rate. The FTIR analysis revealed that Pb and Cd accumulation in plants induced changes in carboxy, amino, hydroxyl and phosphate groups that ultimately caused alteration in physiological and biochemical processes of plant and thus provided an insight to the interaction, binding and accumulation of heavy metals.

Controlling factors and sources-specific ecological risks associated with toxic metals in core sediments from cascade reservoirs in Southwest China

Toxic metals (TMs) in reservoir sediments pose significant risks to ecosystem security and human safety, yet their presence in the cascade reservoirs of the Lancang River remains understudied. This research examined TMs in core sediments from the Manwan (MW) and Dachaoshan (DCS) cascade reservoirs, aiming to elucidate contamination characteristics, controlling factors, and source-specific ecological risks. The study revealed that the concentrations of As, Cd, Cr, Cu, Hg, Ni, and Zn in the MW Reservoir (37.3, 0.54, 95.1, 44.0, 0.09, 44.8, and 135.7 mg/kg) were notably higher compared to the DCS Reservoir (14.6, 0.30, 82.6, 31.0, 0.08, 36.6, and 108.7 mg/kg). While both reservoirs demonstrated elevated contamination levels of Cd and Hg, the MW Reservoir also exhibited high levels of As, whereas the DCS Reservoir showed relatively high levels of Pb. Mining activities in upstream metal deposits significantly correlated Cd, Hg, and Zn in the MW Reservoir with sulfur. In both reservoir sediments, Cr and Ni displayed a greater affinity for iron oxides, while As, Cd, Cu, Hg, and Zn showed more affinity with manganese oxides. Ecological risk index (RI) values in half of the sediments from the MW Reservoir ranged from 300 to 600, denoting a significant ecological risk. Conversely, in the DCS Reservoir, 93.3 % of the sediments exhibited RI values between 150 and 300, signifying a moderate ecological risk. Source-oriented ecological risks highlighted the need for particular attention to Cd from anthropogenic sources in the MW Reservoir. These findings underscore the importance of implementing measures for TM contamination prevention and control, contributing to strategic planning for sustainable water resource management in the Lancang-Mekong River.

Unveiling a Technosol-based remediation approach for enhancing plant growth in an iron-rich acidic mine soil from the Rio Tinto Mars analog site

This paper explores the potential of Technosols made from non-hazardous industrial wastes as a sustainable solution for highly acidic iron-rich soils at the Rio Tinto mining site (Spain), a terrestrial Mars analog. These mine soils exhibit extreme acidity (pHH2O = 2.1–3.0), low nutrient availability (non-acid cation saturation < 20 %), and high levels of Pb (3420 mg kg−1), Cu (504 mg kg−1), Zn (415 mg kg−1), and As (319 mg kg−1), hindering plant growth and ecosystem restoration. To address these challenges, the study systematically analyzed selected waste materials, formulated them into Technosols, and conducted a four-month pot trial to evaluate the growth of Brassica juncea under greenhouse conditions. Technosols were tailored by adding varying weight percentages of waste amendments into the mine Technosol, specifically 10 %, 25 %, and 50 %. The waste amendments comprised a blend of organic waste (water clarification sludge, WCS) and inorganic wastes (white steel slag, WSS; and furnace iron slag, FIS). The formulations included: (T0) exclusively mine Technosol (control); (T1) 60 % WCS + 40 % WSS; (T2) 60 % WCS + 40 % FIS; and (T3) 50 % WCS + 16.66 % WSS + 33.33 % FIS. The analyses covered leachate quality, soil pore water chemistry, and plant response (germination and survival rates, plant height, and leaf number). Results revealed a significant reduction in leachable contaminant concentrations, with Pb (26.16 mg kg−1), Zn (4.94 mg kg−1), and Cu (2.29 mg kg−1) dropping to negligible levels and shifting towards less toxic species. These changes improved soil conditions, promoting seed germination and seedling growth. Among the formulations tested, Technosol T1 showed promise in overcoming mine soil limitations, enhancing plant adaptation, buffering against acidification, and stabilizing contaminants through precipitation and adsorption mechanisms. The paper stresses the importance of tailoring waste amendments to specific soil conditions, and highlights the broader implications of the Technosol approach, such as waste valorization, soil stabilization, and insights for Brassica juncea growth in extreme environments, including Martian soil simulants.

Ecological Status of Algeciras Bay, in a Highly Anthropised Area in South-West Europe, through Metal Assessment-Part I: Abiotic Samples.

The ecological status of Algeciras Bay (South-west Europe), highly influenced by anthropogenic activities, was assessed by monitoring Zn, Cd, Pb, and Cu in water and sediment samples. Total contents and metal fractions with different availabilities and their spatial-seasonal distribution were determined. The trend in water and sediment contents were Zn > Pb ≈ Cu > Cd, without significant seasonal variations. Sites 3 and 4, closest to industrial activities, had the highest metal concentrations, mainly in sediments. Cd showed low partition coefficient in water, indicating higher bioavailability. Total metal content in sediments exceeded the threshold effect level for Cu and were close to Pb. The BCR procedure revealed the highest availabilities for Cd and Pb, due to its higher content in exchangeable and reducible fractions. Higher Pb levels (21.4 ± 5.1 mg/kg) were found in sediments of this bay compared with other ecosystems. Pollution indexes for sediment quality revealed that site 3 was the most polluted (CF = 7.12 and Igeo = 2.25). For an integrative study of the ecological status of this significant bay, these results have been complemented with the metal evaluation in benthic and benthopelagic fish tissues in Ecological status of Algeciras Bay, in a highly anthropised area in south-west Europe, through metal assessment-Part II: Biotic samples.

Can blood morphology, oxidative stress, and cholinesterase activity determine health status of pigeon Columba livia f. urbana?

Environmental studies in Northern Poland are example of the functioning of ecophysiological relationships under anthropogenic impact. The aim of our studies was to investigate sex-dependent effects on the alterations in the concentration of chemical elements in soil samples collected from habitats of feral pigeon Columba livia f. urbana from Northern Poland, as well as feathers, biomarkers of oxidative stress, antioxidant defense, and total cholinesterase activity in tissues (liver, kidney, brain). Concentration of Si, Zn, and Pb in feathers of pigeons was significant. The levels of Si and Zn were higher in feathers of females from non-polluted, while higher Pb levels were found only in females from polluted areas (p = 0.000). This was confirmed by MANOVA of biomarkers of antioxidant defense, elements concentration, and revealing the order of effects: tissue type > environment > sex. Erythrocytes of males living in polluted areas were more fragile to hemolytic agents resulting in a higher percentage of hemolyzed erythrocytes. The effects of polluted environment on the level of carbonyl derivatives of oxidatively modified proteins compared to the effects of sex were more pronounced in the case of kidney (p = 0.000) and hepatic tissues (p = 0.000). Polluted areas were associated with significant increase in SOD activity in the brain and hepatic tissues of pigeons (p = 0.000). Health status of feral pigeons is significantly different in conditions of environmental destabilization.

Health Risks for Consumers of Forest Ground Cover Produce Contaminated with Heavy Metals.

The activity of heavy metal (HM) mining and processing industries causes soils contamination with HM. The metals could be transferred from contaminated soils to edible plants and fungi. This study aimed to assess the content of Cd, Pb, Hg, As, and Ni in berries and edible mushrooms collected in the forests located near Miasteczko Slaskie zinc smelter and in the Lubliniec region, in the context of consumers' health risk. The ET-AAS method was used to determine the content of Cd, Pb, Ni, and As. Mercury concentration was determined using the CV-AFS method. The studies showed high levels of Cd and Pb in the examined products. A statistically significant impact of the distance from the smelter on the Cd concentration in the berries was observed. Total non-cancer health risk from the combined exposure of adults to all HM in mushrooms and berries was significant when consuming the most heavily contaminated produce. The risk to children was significant, even when consuming products with moderate levels of the metals. Ingestion of Cd by children with mushrooms was related to a high cancer risk. The uncertainty of the results was determined. It is recommended to take action to increase awareness among residents of the areas adjacent to the forests regarding the existing health risk and to take possible measures to reduce exposure to HM.

Serum and Seminal Plasma Levels of Lead and Arsenic in Cigarette Smokers and Their Relation to the Semen Parameters

Male infertility along with altered semen parameters have been related to smoking. Smoking-related elevations in serum and seminal lead (Pb) and arsenic (As) may play a role in mediating the toxic effects of smoking on seminogram. This research aims to determine whether smoking has any significant impact on Pb and As levels in the seminal plasma and serum, as well as on the various semen parameters, when compared to nonsmokers. In total, 80 adult males were included: 60 smokers and 20 age-matched nonsmokers. Based on the number of cigarettes smoked/day (CPD), the smokers were categorized into mild (1–10), moderate (11–20), and severe (> 20). The analysis of semen was conducted in accordance with the 2010 WHO laboratory manual. Using an atomic absorption spectrophotometer, Pb and As concentrations in the serum and seminal plasma of all groups were determined. Compared to nonsmokers, smokers had a significantly reduced sperm count, motility, and viability, as well as a larger percentage of aberrant forms (P = 0.001, 0.025, 0.034, 0.002 respectively). Smokers had higher Pb concentrations in their serum and seminal fluid than nonsmokers (P = 0.002, 0.001 respectively). Seminal Pb had a significant negative correlation with sperm count (P = 0.004, r = -0.320). Serum Pb levels were found to positively correlate with seminal Pb levels (P 0.001, r = 0.648), and cigarette smokers had substantially greater seminal As levels than nonsmokers (P = 0.024). Sperm viability was strongly inversely related to seminal As (P = 0.042, r = -0.264). Seminal As levels and aberrant sperm shapes were found to be significantly correlated (P = 0.001, r = 0.414). In smokers, a significant positive relationship between seminal As and seminal Pb was observed. Therefore, semen parameters could be adversely affected by smoking through high levels of Pb and As (P = 0.012, r = 0.298).

Spatio-temporal variability of public water supply characteristics and associated health hazards for children and adults in selected locations of Ambala, India.

The contamination of public water supply and groundwater resources is a major concern in many parts of developing nations. Polluted water poses serious health risks to humans and the environment. This research was conducted to investigate the seasonal variations of the water quality parameters in the public water supply. To assess the supply water quality in different blocks of Ambala District, hydro-chemical analysis was conducted after a series of systematic sampling in various locations. The statistical tools for water quality indexing including water quality indexing (WQI), heavy metal pollution indexing (HMPI), pollution indexing (PI), overall pollution indexing (OPI), metal indexing (MI), and hazard indexing (HI) were used for data as well as the health hazard analysis through water pathway. Overall, 40 water samples were taken from the public water supply systems covering winter and summer seasons, and the levels of pH, total dissolved solids (TDS), EC, F- , Cl- , NO3 - , SO4 2- , HCO3 - , As, B, Cd, Co, Pb, Zn, Cr, Fe, and Mn were investigated. The weight arithmetic index method was used for WQI, and water pollution indices such as HMPI, PI, OPI, and MI were calculated using different models to check the severity of contamination. The mean hazard quotient and hazard index values calculated using the concentration levels of As, B, Cd, Co, Pb, Cr, Fe, Mn, Zn, F- , and NO3 - reveal that supply water may pose a significant health risk to both adults and children that further varies with temporal and spatial changes. During both seasons, a high carcinogenic risk for both adults and children was observed in the studied area because of high levels of As, Pb, Cd, and NO3 - . PRACTITIONER POINTS: The quality of public supply water was assessed at the selected sites of Ambala, India. High levels of NO3 - , As, Cd, and Pb were observed posing a health risk to adults and children via water pathway. 95% of the samples qualified for the excellent water quality category with respect to the levels of F- , Cl- , NO3 - , SO4 2- , HCO3 - , pH, EC, and TDS. Statistical analysis (HMPI, PI, MI, OPI, HI) using different models revealed water contamination with reference to the levels of NO3 - , As, Pb, Cr, Ni, and Cd. Immediate measures are needed to uphold the safety and health of the natives.

REDUCTION RATE OF SOME HEAVY METAL IN DIFFERENT CONCENTRATIONS USING Pseudomonas aeruginosa ISOLATED FROM TENNARY WASTEWATER EFFLEUNT

Industrial developments led to environmental pollution with toxic heavy metals which spreading all over the world. Heavy metal pollution, characterized by its heightened toxicity, resistance to biodegradation, and biological accumulation, has significantly jeopardized both human health and ecological stability. Microbial activities offer a potential avenue for immobilizing, removing, and detoxifying active heavy metal ions in the natural environment. This research aimed to study the ability of Pseudomonas aeruginosa in reducing the amount of Cd, Ni, Cr, Zn and Pb that found in tannery wastewater and to investigate its survivability in high concentrations of these metals. In this study Pseudomonas aeruginosa, was isolated from tannery effluents wastewater. Pseudomonas aeruginosa has been incubated in medium contained 50, 100, 300, 500 and 1000 ppm of Cd, Ni, Cr, Zn and Pb for 6, 12 and 24hrs at 37 °C. Results showed that Pseudomonas aeruginosa was able to cause a significant reduction of Cd, Ni, Cr, Zn and Pb at incubation time of 24 hours at concentration of 50, 100 and 300 ppm ,the reduction level for Ni were (96.5%, 96.2% and 96.4 %) respectively, Cd (76.4%, 82.1% and 83.8 % )respectively, Cr showed reduction rates of ( 97.7% , 99.4% and 99.1%) respectively, Pb ( 87.3% ,91.9% and 89.6%) respectively, and (82%, 87.6% and 80.1 %) respectively for Zn, Pseudomonas aeruginosa was not able to grow at concentration level of 500 and 1000 ppm for Cd, Ni, Cr, Zn and Pb. These results indicated that Pseudomonas aeruginosa is able to survive in tannery effluents wastewater containing high levels of Cd, Ni, Zn, Cr and Pb. Therefore, more research is recommended to study the ability of this species to remove Cd, Ni, Cr, Zn and Pb in different conditions.

Origin, spatial distribution, sediment contamination, ecological and health risk evaluation of trace metals in sediments of ship breaking area of Bangladesh

Eleven trace metals (Cd, Cr, Fe, Mn, Cu, Ni, Co, Zn, As, Pb, and Ag) in sediments of Bangladesh’s ship breaking area were measured by an atomic absorption spectrometer to determine origin, contamination extent, spatial distributions, and associated ecological and human health hazards. This study found considerable quantities of Pb, Cd, Mn, Zn, and Cu when compared with standards and high levels of Pb, Cd, Zn, Cu, As, and Ag contamination according to pollution evaluation indices. Different indices indicate most of the sampling sites were highly polluted. However, spatial distribution maps indicate that trace metals were predominantly deposited in the northern and southern region. The ecological risk index revealed that Cd has the highest while Pb and As had moderate risk. Based on the health index values, Zn for both adults and children were higher than the safe limit while Mn, Pb, Cr, As, Fe, Cu, Ni, and Co for children were close to the threshold. The mean total carcinogenic risk values of Cr, As, and Ni for children and Ni for adults exceeded the permissible threshold. The cancer risk possibilities were further assessed using Monte Carlo simulation. Most trace metals have anthropogenic origins, which were attributed to ship breaking activities.

Assessing lead and cadmium tolerance of Chenopodium ambrosioides during micropropagation: an in-depth qualitative and quantitative analysis.

The tolerance of Chenopodium ambrosioides to some heavy metals under in vitro environment was thoroughly investigated. A micropropagation protocol was developed to facilitate the mass production of plants and to identify metals-tolerant species for potential use in the restoration of polluted areas. Nodal explants exhibited callus formation when treated with N6-benzyladenin (BA) (1.5 mg/l) and a combination of BA/α-naphthalene acetic acid (NAA) at concentrations of 1.5/1.0 mg/l on the Murashige and Skoog (MS) medium. The optimal shoot formation was achieved with the callus grown on a medium enriched with 1.5/1.0 mg/l BA/NAA, resulting in an impressive number (21.89) and length (11.79 cm) of shoots. The in vitro shoots were rooted using NAA (1.0 and 1.5 mg/l) and were acclimatized in pots with 71% survival rate. After standardizing micropropagation protocol, the in vitro shoots were subjected to various doses of lead nitrate (Pb(NO3)2 and cadmium chloride (CdCl2). Pb(NO3)2 and CdCl2 in the media let to a reduction in shoot multiplication, decreasing from 18.73 in the control group to 11.31 for Pb(NO3)2 and 13.89 for CdCl2 containing medium. However, Pb(NO3)2 and CdCl2 promoted shoot length from 5.61 in the control to 9.86 on Pb(NO3)2 and 12.51 on CdCl2 containing medium. In the case of Pb(NO3)2 treated shoots, the growth tolerance index (GTI) ranged from117.64% to 194.11%, whereas for CdCl2 treated shoots, the GTI ranged from 188.23% to 264.70%. Shoots treated with high level of Pb(NO3)2induced reddish-purple shoots, while a low level of Pb(NO3)2 induced shoots displayed both green and reddish-purple colors in the same explants. In CdCl2 treated culture, the toxic effects were narrow leaf lamina, elongated petiole and a dark reddish purple coloration. These findings highlight the remarkable potential of C. ambrosioides to maintain growth and organogenesis even in the presence Pb(NO3)2 and CdCl2 on the MS medium, indicating a high degree of metal tolerance.

Elemental levels in frequently consumed local leafy vegetables from three villages with chronic kidney disease prevalence

Studies on elemental levels in frequently consumed local edibles in any region with a localized disease are meaningful. The present study has identified the levels of 24 elements in nine (6 cultivated and 3 wild) frequently consumed local leafy vegetables from three chronic kidney disease prevalent villages (a total 27samples) using ICP-MS. The comparison of obtained levels of these elements with WHO/FAO permissible values reveals the levels of Ba in all the tested samples, Pb in 15 samples is in excess, whereas Fe and Zn levels are below the required levels, and the other elements are in the permissible levels. Among the 27 tested samples, a high level of Ba was found in Allium cepa of L3, and Pb was in Amaranthus viridis of L2. Among the leafy vegetables Allium cepa from L3 and Amaranthus viridis from L2 showed high levels of Ba and Pb, respectively. In the three locations studied, average Ba and Pb levels are found more in Borivanka (L3) followed by Kusumapuram (L1) and Varaka (L2). Ba levels are excess in both cultivated and wild leafy vegetables, while Pb levels are slightly higher in cultivated than the wild leafy vegetables, which may be due to the usage of chemical pesticides and fertilizers. The present study signifies that frequent consumption of such leafy vegetables may influence the renal functioning in this area, along with other factors like drinking water, other edibles.

Heavy metal toxicity arising from the industrial effluents repercussions on oxidative stress, liver enzymes and antioxidant activity in brain homogenates of Oreochromis niloticus

Industrial effluents reaching to the aquatic ecosystem is one of the major causes of environmental pollution and exposure to industrial effluents containing harmful substances may be a serious threat to human health. Therefore, the present study aimed to determine the sub-lethal (1/5th of predetermined LC50) impact of industrial effluents from Sundar Industrial Estate on Oreochromis niloticus with proper negative control. The physicochemical analysis of industrial effluents showed enormous loads of inorganic pollutants and exhibited high mean levels of heavy metals, Mn, Fe, Pb, Ni, Cr, Hg, As, Zn and Fe with statistically significant differences at p < 0.05. Highest level of Mn and Fe was detected in effluent’s samples as 147.36 ± 80.91 mg/L and 90.52 ± 32.08 mg/L, respectively. Exposure led to increase in serum biochemical parameters alanine aminotransferase + 25%, aspartate aminotransferase + 20% and alkaline phosphatase + 7% over control although superoxide dismutase, catalase, glutathione peroxidase and reduced glutathione significantly increased as 3.42, 2.44, 4.8 and 8 folds, respectively in metabolically active tissue brain which indicated stress caused by industrial effluents. The results concluded that industrial effluent has potent oxidative stress inducers on one hand whereas histoarchitectural and physiological toxicity causing contaminants on the other. This condition may adversely affect the health of aquatic organisms, the fish and ultimately the human beings.

Nematofauna of the Natural Park “Devil’s Town”

“Devil’s Town” is a natural park dominated by broadleaf deciduous trees, and made up of two rare natural phenomena in the world: earthen statues, as specific forms of relief, and two springs of highly acidic water with high mineralization. Devil’s Town is a “biodiversity star” with a unique ambient, flora, fauna, and microbiome. The research aimed to: investigate the concentration of chemical parameters in the soil of the natural park, identify nematodes that can survive in extreme conditions, explore feeding habits of nematodes, and infer phylogenetic relationships of nematodes based on 28S rRNA sequences. Soil samples were collected from two sites, designated Soil under vegetation and Saxon mine soil, from which nematodes were discovered. Phylogenetic analyses were performed with 28S rRNA gene primers, using Maximum likelihood and Bayesian inference. The presence of minerals and heavy metals, combined with high acidity created extreme environmental conditions in which specific nematode species can survive. These circumstances favored fast-moving species with teeth and spears, such as mononchids and dorylaimids, enabling them to adopt predatory feeding behavior. In contrast, Acrobeloides, Prismatolaimus, Rhabditis spp. etc., are saprobionts adapted to specific chemical pollutants, and they tolerate high levels of Pb, Zn, Fe, Cu, Cd and As.

Zooplankton as an indicator of the status of contamination of the Mediterranean Sea and temporal trends

Zooplankton has been intensively used as bioindicators of water pollution at global level, however, only few comprehensive studies have been conducted from the Mediterranean Sea and manly dated back to the 1970s. To redress the urgent need for updated data, this study provides information on the presence and levels of contaminants in zooplankton from the Tyrrhenian Sea. Although banned, both PCBs (46.9 ± 37.2 ng g−1) and DDT (8.9 ± 10.7 ng g−1) are still present and widespread, but their contamination appears to be a local problem and to be declining over the past 50 years. Zooplankton accumulates high levels of certain TEs, including Zn (400 ± 388 ppm) and Pb (35.3 ± 45.5 ppm), but shows intermediate concentrations of other TEs, including Cd (1.6 ± 0.9 ppm) and Hg (0.1 ± 0.1 ppm), comparing with both strongly polluted and more pristine marine habitats, which may reflect a general improvement.

Calculating Health and Ecological Risks of Pm2.5, and Lead Pollutants Exposure Among Communities Due to Cement Plant Emission, Maros Indonesia 2023

Purpose: This study assessed the possible impacts of PM 2.5, and Lead exposures on populations and ecology as a result of breathing contaminated air and contaminated soil exposure near the Bosowa cement mill in Maros, Indonesia in 2023. Theoretical Framework: Anthropogenic and lithogenic activities can lead to an increase in the amount of heavy metals in ambient air and in soil as well as a decline in the quality of the environment. Methods: The magnitude of PM 2.5, and Lead were measured during the period of April-June 2023. The level of PM 2.5 on ambient air sampling was conducted using direct reading HAZ-Dust EPAM 5000, uses a laser analyzer in order to measure particulate level matter. The result or time-weighted average (TWA) value directly can be read after the measurement at the site. Then meteorological data was collected from Indonesia Agency for Meteorology, Climatology, and Geophysics online database. Then, lead concentrations on surface Soil were taken and analyzed using AAS. Potential ecological and human health risks. Results and Conclusion: Station 9 had the highest level of PM 2.5 concentration (98.23 g/m3), followed by station 11 (97.14 g/m3). In comparison, station 3 had the lowest amount at (31.24 g/m3) and station 5 had the highest level at 32.91 g/m3, respectively. Additionally, station 10 had the greatest amount of Pb air particulate concentration, followed by station 11 with 88.33 g/m3, while station 6 had the highest level of Pb in surface soil, at 196.90 and 166.91 mg/g, respectively. In comparison, station 15 had the lowest amount at (54.76 mg/g), and station 14 had the highest level at (88.87 mg/g), respectively. The findings implied that both PM2.5 and Pb have medium risks to exposed communities. It could be valuable for managing the air quality due to the industry activities and soil remediation in residential areas. Research Implications: Exposure to PM2.5 and Pb air particulates is more hazardous to the environment than it is to human health. PM2.5 and Pb levels in the soil and air had accumulated. More thought should be given, and remedial action should be set to lowering PM2.5 and Lead concentrations and their consequences on the environment in the research region. Originality/value: This study encompasses relevant study that have conducted between 1990 and 2022 and lucidly summarizes the magnitude of PM2.5 and Pb in the air and soil, in addition this research emphasize the risks of environmental and human due to the PM2.5 and Pb Contamination acutely and chronically.

Associations of 10 trace element levels in the whole blood with risk of three types of obesity in the elderly.

Currently, over 2 billion people worldwide suffer from obesity, which poses a serious health risk. More and more attention is being given to the effects of trace elements on obesity in recent years. Synergistic or antagonistic interactions among these elements can adversely or positively impact human health. However, epidemiological evidence on the relationship between trace element exposure levels and obesity has been inconclusive. Baseline data of 994 participants from the Cohort of Elderly Health and Environment Controllable Factors were used in the present study. ICP-MS was used to measure the concentrations of 10 trace elements in the whole blood of the older population. Binary logistic regression, restricted cubic splines (RCS) models, and Bayesian kernel machine regression (BKMR) models were employed to assess single, nonlinear, and mixed relationships between 10 trace element levels and three types of obesity based on body mass index (BMI), waist circumference (WC), and body fat percentage (BFP) in the elderly. Based on BMI, WC and BFP, 51.8% of the included old population were defined as general overweight/obesity, 67.1% as abdominal obesity, and 36.2% as having slightly high/high BFP. After multivariable adjustment, compared with the lowest tertile, the highest tertile of blood selenium (Se) concentration was associated with an increased risk of all three types of obesity. Additionally, compared with the lowest tertile, higher tertiles of strontium (Sr) concentrations were associated with a lower risk of general overweight/obesity and having slightly high/high BFP, and the highest tertile of barium (Ba) was associated with a lower risk of having slightly high BFP, while higher tertiles of arsenic (As) concentrations were associated with an increased risk of having slightly high/high BFP, and the highest tertile of manganese (Mn) was associated with a higher risk of abdominal obesity. BKMR analyses showed a strong linear positive association between Se and three types of obesity. Higher blood levels of trace element mixture were associated with increased obesity risks in a dose-response pattern, with Se having the highest value of the posterior inclusion probability (PIP) within the mixture. In this study, we found higher Se levels were associated with an elevated risk of obesity and high levels of Ba, Pb and Cr were associated with a decreased risk of obesity. Studies with larger samples are needed to confirm these findings.

Toxic Metals Contamination of Cattle Hide Singed With Scrap Tyres

Processed cattle hide popularly known as “Ganda” in Nigeria is widely eaten as a substitute for meat but the commercial method of processing this food delicacy through singeing with scrap tyres has become a source of concern due to possible heavy metals contamination. This study evaluates the presence and levels of Cd, Cu, Fe, Pb, and Zn in the cattle hide samples obtained by using Atomic Absorption Spectrophotometry (AAS). The hide samples analyzed were obtained from seven states across the three geopolitical zones in northern Nigeria. Cd was not detected in most of the samples, notably from Niger, Zamfara, Adamawa and Plateau states, while concentrations of 0.0001±5.77E-5, 0.0005±4.71E-5, and 0.009±0.001 mg/kg detected from Kano, Kaduna, and Taraba, respectively, were lower than the maximum permissible level of 0.05 mg/kg set by the reference limits. Pb concentrations in all the samples analyzed were 1.080±0.072 to 1.760±0.160 mg/kg which surpassed the maximum permissible level of 0.1 mg/kg set by the reference limits, while other heavy metals were below the safe limits. The high levels of Pb introduced to the singed hide beyond the reference limits could be linked to the use of scrap tyres in the burning hairs of the hide, and it could be of great concern after consumption. In view of the above possible health implications that might arise, a detailed and proper health risk assessment technique needs to be employed in future research.

Exploring the association of metal mixture in blood to the kidney function and tumor necrosis factor alpha using machine learning methods

This research aimed to approach relationships between metal mixture in blood and kidney function, tumor necrosis factor alpha (TNF-α) by machine learning. Metals levels were measured by Inductively Couple Plasma Mass Spectrometry in blood from 421 participants. We applied K Nearest Neighbor (KNN), Naive Bayes classifier (NB), Support Vector Machines (SVM), random forest (RF), Gradient Boosting Decision Tree (GBDT), Categorical boosting (CatBoost), eXtreme Gradient Boosting (XGBoost), Whale Optimization-based XGBoost (WXGBoost) to identify the effect of plasma metals, TNF-α, and estimated glomerular filtration rate (eGFR by CKD-EPI equation). We conducted not only toxic metals, lead (Pb), arsenic (As), cadmium (Cd) but also included trace essential metals, selenium (Se), copper (Cu), zinc (Zn), cobalt (Co), to predict the interaction of TNF-α, TNF-α/white blood count, and eGFR. The high average TNF-α level group was observed among subjects with higher Pb, As, Cd, Cu, and Zn levels in blood. No associations were shown between the low and high TNF-α level group in blood Se and Co levels. Those with lower eGFR group had high Pb, As, Cd, Co, Cu, and Zn levels. The crucial predictor of TNF-α level in metals was blood Pb, and then Cd, As, Cu, Se, Zn and Co. The machine learning revealed that As was the major role among predictors of eGFR after feature selection. The levels of kidney function and TNF-α were modified by co-exposure metals. We were able to acquire highest accuracy of over 85% in the multi-metals exposure model. The higher Pb and Zn levels had strongest interaction with declined eGFR. In addition, As and Cd had synergistic with prediction model of TNF-α. We explored the potential of machine learning approaches for predicting health outcomes with multi-metal exposure. XGBoost model added SHAP could give an explicit explanation of individualized and precision risk prediction and insight of the interaction of key features in the multi-metal exposure.

Characteristic features of toxic metal content in hair samples of foreign students at RUDN University from different geographic regions

BackgroundThis study explores the regional variations in toxic metal accumulation among RUDN University students from various global regions. MethodsThis comparative analysis examined hair samples from students hailing from different regions, including Russia, Asia, the Middle East, Africa, and Latin America. The concentrations of Aluminium (Al), Arsenic (As), Cadmium (Cd), Mercury (Hg), Lead (Pb), and Tin (Sn) were measured in the hair samples. The data was then evaluated using regression models to assess the link between the region of residence and toxic metal content in the hair. ResultsThe analysis indicated significant regional variations in the levels of toxic metals in the students' hair. The highest content of Al, Cd, and Pb was observed in students from Africa (13.542, 0.028, 0.794 µg/g) and Latin America (9.947, 0.025, 0.435 µg/g). Arsenic levels in students from all regions exceeded that of Russian students by over two-fold. No substantial group differences were found in the Sn content. The regression models suggested that residing in Asia, Africa, and Latin America was a predictor of high Hg levels in hair (0.130, 0.096, 0.227 µg/g). Living in Africa was significantly associated with higher Pb levels (0.794 µg/g), and living in Latin America was close to significantly associated with the Cd level in the hair (0.025 µg/g). ConclusionThis study confirmed an increased accumulation of toxic metals, especially Hg, Cd, and Pb, in students primarily from Latin America and Africa. The findings highlighted the importance of understanding the regional variations in toxic metal accumulation to address associated health risks and the potential impact on students' well-being and academic performance. These insights may guide the development of targeted interventions to reduce exposure to toxic metals in students from various regions around the world.