Urbanization is a complex process reflecting the growth, formation and development of cities and their systems. Measuring regional urbanization levels within a long time series may ensure healthy and harmonious urban development. Based on DMSP/OLS nighttime light data, a human—computer interactive boundary correction method was used to obtain information about built-up urban areas in the Bohai Rim region from 1992 to 2012. Consequently, a method was proposed and applied to measure urbanization levels using four measurement scale units: administrative division, land-sea location, terrain feature, and geomorphological types. Our conclusions are: 1) The extraction results based on DMSP/OLS nighttime light data showed substantial agreement with those obtained using Landsat TM/ETM+ data on spatial patterns. The overall accuracy was 97.70% on average, with an average Kappa of 0.79, indicating that the results extracted from DMSP/OLS nighttime light data were reliable and could well reflect the actual status of built-up urban areas. 2) Bohai Rim’s urbanization level has increased significantly, demonstrating a high annual growth rate from 1998 to 2006. Areas with high urbanization levels have relocated evidently from capital to coastal cities. 3) The distribution of built-up urban areas showed a certain degree of zonal variation. The urbanization level was negatively correlated with relief amplitude and altitude. A high level of urbanization was found in low altitude platforms and low altitude plains, with a gradual narrowing of the gap between these two geomorphological types. 4) The measurement method presented in this study is fast, convenient, and incorporates multiple perspectives. It would offer various directions for urban construction and provide reference values for measuring national-level urbanization.