Higher Levels Of Alcohol Consumption Research Articles

Folate intake and the risk of breast cancer: an up-to-date meta-analysis of prospective studies.

Epidemiological studies focusing on the association between folate and breast cancer risk reported inconsistent findings. We conducted a systematic search of the literature using PubMed and EMBASE databases. A total of 23 prospective studies involving 41,516 cases and 1,171,048 individuals were included for meta-analysis. Folate intake may decrease the risk of oestrogen receptor (ER) negative (-) and ER-/progesterone receptor (PR)- breast cancer, with pooled risk ratios (RRs) of 0.88 [95% confidence interval (CI): 0.78-1.00] and 0.82 (95% CI: 0.68-0.97), respectively. An increment of folate intake of 100 μg per day was associated with a deceased risk of ER- (RR = 0.94, 95% CI: 0.88-0.99) and ER-/PR- (RR = 0.90, 95% CI: 0.85-0.97) breast cancer. Moreover, high folate intake may have preventive effects against breast cancer in premenopausal women (RR = 0.94, 95% CI: 0.88-1.00) and individuals with moderate or high levels of alcohol consumption (RR = 0.82, 95% CI: 0.72-0.94).

Too little, too much or just right: Injury/illness sensitivity and intentions to drink as a basis for alcohol consumer segmentation

Background: Although alcohol is the most socially accepted drug, little is known about the classification of alcohol consumers into clusters influencing drinking outcomes. Past research has demonstrated that injury/illness sensitivity predicts health protecting behaviors. Objectives: The present study explored whether alcohol consumers can be classified based on injury/illness sensitivity and intentions to reduce drinking, and whether the identified clusters exhibited meaningful differences in negative affect and drinking levels. Methods: Four-hundred and eighty-six participants (54.3% male; mean [SD] age = 26.5 [7.2] years) completed online questionnaires between July and October of 2017. Questions were asked pertaining to injury/illness sensitivity, intentions to reduce drinking, negative affect, and heavy drinking behavior. A k-means cluster analysis was performed on illness/injury sensitivity and intentions to reduce drinking scores. We then examined whether clusters varied according to negative affect or drinking variables. Results: The k-means cluster analysis identified four clusters: Insensitive non-internalizers, Insensitive internalizers, Sensitive non-internalizers, and Sensitive internalizers. Sensitive internalizers reported the highest, whereas Insensitive non-internalizers reported the lowest, negative affect. Sensitive internalizers also had the lowest percentage of heavy drinkers. Conclusion/importance: Current findings add to the alcohol literature by indicating that high sensitivity to illnesses/injuries and the internalization of sensitivities via behavior change intentions may provide the best protection against high alcohol consumption levels.

Prevalence and characteristics associated with concurrent smoking and alcohol misuse within Australian general practice patients.

Objectives This study sought to determine, among a large sample of Australian general practice patients: (1) the prevalence of smoking among different levels of alcohol misuse; and (2) whether the associations between demographic characteristics and alcohol use differ according to smoking status. Methods A cross-sectional survey was administered from 2010 to 2011 to 3559 patients from 12 Australian urban general practices. Patients reported their demographic details, smoking status and their alcohol intake. Results The overall prevalence of reported concurrent smoking and alcohol misuse was 7.8%. Smokers were 3.81-fold more likely to have a higher level of alcohol consumption than non-smokers (95% confidence interval 3.13-4.63; P<0.0001). There was evidence that smoking was an effect modifier of the relationship between alcohol misuse and chronic illness. Conclusions There was an increasing prevalence of smoking with increasing level of alcohol consumption. In addition, those with chronic conditions who smoked had greater odds of higher levels of alcohol consumption. Preventative interventions for these substances are needed to reduce the burden associated with concurrent smoking and alcohol misuse. What is known about the topic? Tobacco and alcohol are the most commonly used substances and contribute to over 10million deaths annually. The risk of disease is high when using either of these substances, however, concurrent use is associated with a greatly compounded risk. Australian data is limited regarding the prevalence of concurrent tobacco and alcohol misuse, however, international studies suggest variation in prevalence rates between different clinical settings. What does this paper add? This study examined the prevalence of concurrent smoking and alcohol misuse among different levels of alcohol misuse severity within an Australian general practice setting. Additionally it explored whether the associations between demographic characteristics and alcohol use differ according to smoking status. What are the implications for practitioners? This study has important implications for disease prevention and the delivery of preventive health services by general practitioners. Considering one in 100 clinical treatments provided in general practice relate to preventative smoking or alcohol counselling, it is critical that efforts are made to ascertain risk factors such as smoking and alcohol misuse to increase treatment rates. General practitioners should consider screening for smoking and alcohol misuse opportunistically during routine clinical encounters, as well as screening for smoking or alcohol misuse if one or the other is present.

Alcohol Consumption and Risk of Incident Frailty: The English Longitudinal Study of Aging

BackgroundAlcohol consumption is a common modifiable lifestyle factor. Alcohol may be a risk factor for frailty, however, there is limited evidence in the literature. ObjectiveThe objectives of this study were to examine the association of alcohol consumption with the risk of incident frailty. MethodsThis is a prospective panel study of 2544 community-dwelling people aged 60 years and older in England. Frailty status defined by frailty phenotype criteria was measured at baseline and 4 years later. Participants free of frailty at baseline were divided into 5 groups based on quantity of self-reported alcohol consumption per week with cut-points at 0, 7, 14, and 21 UK units per week. Adjusted odds ratios (OR) were calculated for incident frailty according to the alcohol consumption using logistic regression models. ResultsCompared with the low consumption group (>0 and ≤7 units per week), incident frailty risk over 4 years was significantly higher among nondrinkers [OR 1.71, 95% confidence interval (CI) 1.12‒2.60, P value = .01], after controlling for sociodemographic confounders. In a supplementary analysis this became nonsignificant after further adjustment for baseline health status. Heavy drinkers (>21 units per week) had a significantly lower incident frailty risk (unadjusted OR 0.45, 95% CI 0.27‒0.75, P < .01), which became nonsignificant on adjustment for sociodemographic factors (OR 0.64, 95% CI 0.37‒1.13, P = .12). Conclusions/ImplicationsWe found that nondrinkers were more likely than those with low alcohol consumption to develop frailty, but this appeared to be explained by poorer baseline health status. No evidence was found for an association between high levels of alcohol consumption and becoming frail. Future studies with information on life-course history of alcohol use, especially for those classified as nondrinkers in old age, are warranted.

Increased Alcohol Consumption Among Swedish 70‐Year‐Olds 1976 to 2016: Analysis of Data from The Gothenburg H70 Birth Cohort Studies, Sweden

The older adult population is increasing worldwide, as is the number of older adults who consume alcohol. Although there is a growing body of research on alcohol consumption among older people, few studies focus on changes in at-risk consumption over time across well-defined birth cohorts of older adults. This study used a serial cross-sectional design in order to compare alcohol consumption patterns among birth cohorts of Swedish 70-year-olds (total n=2,268) examined in 1976 to 1977 (n=393), 1992 to 1993 (n=248), 2000 to 2002 (n=458), and 2014 to 2016 (n=1,169). Participants took part in a multidisciplinary study on health and aging. Face-to-face interviews were conducted by healthcare professionals. Protocols regarding alcohol consumption were similar for all cohorts. The volume of weekly alcohol consumption was estimated during the past month. At-risk consumption was defined as ≥100g alcohol/wk corresponding roughly to the National Institute on Alcohol Abuse and Alcoholism definition of heavy consumption. The proportion of at-risk consumers among men increased from 16.1% in 1976 to 1977 to 29.9% in 2000 to 2002 (p=0.001) and 45.3% in 2014 to 2016 (p<0.001). In women, proportions were low in 1976 to 1977 (0.5%) and 1992 to 1993 (2.0%; p=0.134), but increased to 9.5% in 2000 to 2002 (p<0.001) and 24.3% in 2014 to 2016 (p<0.001). The male:female ratio regarding consumption of ≥100g/wk decreased from 32.2:1 in 1976 to 1977 to 3.1:1 in 2000 to 2002 to 1.9:1 in 2014 to 2016. Spirit consumption decreased dramatically among men during the study period, while women reported very low spirit consumption at all examinations. Wine consumption increased in both sexes between 2000 to 2002 and 2014 to 2016. Beer consumption increased among men between 2000 to 2002 and 2014 to 2016. Recent cohorts of 70-year-olds in Sweden report significantly higher levels of alcohol consumption than previous cohorts. There was a dramatic increase in at-risk consumption among 70-year-olds from the 1970s to the mid-2010s, and this was particularly pronounced among women.

Persistent "Sag" in Prefrontal Cortex Function following Adolescent Binge Drinking.

Binge drinking, intermittent periods with high levels of alcohol consumption, is common among human adolescents. Alcohol exposure during adolescence can exert persistent effects on brain maturation and increase the risk of developing an alcohol use disorder (AUD) later in life. One key brain region

Distraction towards contextual alcohol cues and craving are associated with levels of alcohol use among youth

BackgroundControlling drinking behaviour requires the ability to block out distracting alcohol cues in situations in which drinking is inappropriate or harmful. However, at present few studies have investigated whether distraction and response inhibition to contextual alcohol cues are related to alcohol use in adolescents and young adults. We aimed to investigate whether tendencies towards distraction and failures of response inhibition in the presence of contextual alcohol cues, and alcohol craving were associated with higher levels of alcohol consumption, beyond what could be explained by demographic variables.MethodsTo test this, 108 participants (Mean age = 21.7, range = 16–27), whom were both drinkers and non-drinkers performed a modified Go/NoGo task tailored to measure distraction and response inhibition in the presence of alcohol cues relative to neutral stimuli. Alcohol craving was assessed using a visual analogue scale of craving for different types of alcohol cues. Levels of alcohol use and problematic alcohol use were assessed using a self-report measure of number of drinking days in the previous month and the Alcohol Use Disorders Identification Test. Data were analysed using sequential multiple regression using a zero-inflated negative binomial distribution model.ResultsDrinking days correlated with distraction but not response inhibition to contextual alcohol cues. Sequential regression analyses revealed that the inclusion of distraction bias accounted for 11% additional variance (significant) in alcohol use, in addition to that explained by demographics alone (17%). Craving for alcohol explained an additional 30% variance (significant) in alcohol use.ConclusionsThe results reported here support the idea that both biased distraction towards alcohol cues and alcohol craving are associated with preceding drinking days, but not necessarily drinking status. Further studies are warranted that address whether cognitive distraction to alcohol-related cues cause or is an effect of alcohol use among youth.

Decreased event-related theta power and phase-synchrony in young binge drinkers during target detection: An anatomically-constrained MEG approach.

The prevalence of binge drinking has risen in recent years. It is associated with a range of neurocognitive deficits among adolescents and young emerging adults who are especially vulnerable to alcohol use. Attention is an essential dimension of executive functioning and attentional disturbances may be associated with hazardous drinking. The aim of the study was to examine the oscillatory neural dynamics of attentional control during visual target detection in emerging young adults as a function of binge drinking. In total, 51 first-year university students (18 ± 0.6 years) were assigned to light drinking ( n = 26), and binge drinking ( n = 25) groups based on their alcohol consumption patterns. A high-density magnetoencephalography signal was combined with structural magnetic resonance imaging in an anatomically constrained magnetoencephalography model to estimate event-related source power in a theta (4-7 Hz) frequency band. Phase-locked co-oscillations were further estimated between the principally activated regions during task performance. Overall, the greatest event-related theta power was elicited by targets in the right inferior frontal cortex and it correlated with performance accuracy and selective attention scores. Binge drinkers exhibited lower theta power and dysregulated oscillatory synchrony to targets in the right inferior frontal cortex, which correlated with higher levels of alcohol consumption. These results confirm that a highly interactive network in the right inferior frontal cortex subserves attentional control, revealing the importance of theta oscillations and neural synchrony for attentional capture and contextual maintenance. Attenuation of theta power and synchronous interactions in binge drinkers may indicate early stages of suboptimal integrative processing in young, highly functioning binge drinkers.

Relation of Alcohol Consumption to Risk of Heart Failure in Patients Aged 65 to 84 Years With Hypertension

Although a high level of alcohol consumption is associated with cardiomyopathy, the benefit or risk of moderate alcohol consumption on incident heart failure (HF) is unknown. This study examined the association between alcohol consumption and risk for HF in older adults with hypertension. The study analyzed data from a cohort of 6,083 participants aged 65 to 84 years at baseline (1995 to 2001) followed for a median of 10.8 years during and after the Second Australian National Blood Pressure Study. Frequency and amount of alcohol consumption were self-reported at baseline and during the clinical trial. The percentages of current drinkers, former drinkers, and never-drinkers at baseline were 4,400 (72%), 394 (6%), and 1,289 (21%), respectively. Incident HF was diagnosed in 183 men and 136 women. After adjustment for multiple confounders, alcohol consumption was not significantly associated with HF. Compared with never-drinkers, the adjusted hazard ratios (95% confidence interval) for those who consume 1 to 7, 8 to 14, and >14 drinks/week at baseline were 0.87 (0.59 to 1.30), 0.96 (0.57 to 1.60), and 0.71 (0.25 to 2.02), respectively in women, and 0.81 (0.47 to 1.38), 0.77 (0.43 to 1.38), and 1.04 (0.59 to 1.84), respectively in men. The findings of lack of an association between alcohol consumption and risk of HF persisted in the analyses comparing the risk of HF across each level of drinking at baseline or at follow-up with never-drinkers. In the present study, there was no evidence for benefit or risk of alcohol consumption, reported at baseline or at follow-up, in relation to incident HF in both men and women.

Alcohol, generosity and empathy

Existing studies suggest that chronic alcohol dependency (or recovery from alcohol dependency) is associated with lower levels of empathy and generosity. We present results from a charitable donation experiment that was designed to test for associations with moderate variation in the level of alcohol consumption rather than with the incidence of chronic dependency. We find that higher levels of alcohol consumption (and also higher levels of alcohol expenditure) are associated with significantly less generosity. However, there is no significant association between alcohol consumption / expenditure and empathy (as measured by the Interpersonal Reactivity Index) or between alcohol consumption / expenditure and materialism (as measured by the Material Values Scale). This suggests that the relationship between alcohol expenditure and generosity may be mediated through some other channel.

The Temporal Rhythm of Alcohol Consumption: On the Development of Young People’s Weekly Drinking Patterns

This article investigates young people’s weekly drinking patterns during late adolescence and young adulthood. The article builds a disaggregated and temporal framework to explain how young people drink on certain days. Using sequence analysis techniques on longitudinal data from a representative Danish survey, the article identifies four drinking patterns (the majority, the weekend drinkers, the weekend bingers and the heavy drinkers). Analyses of the transitions between the drinking patterns reveal non-linear developments where heavy drinking at an early age does not necessarily lead to heavy drinking later in life. Although parental income and education are important factors to explain whether young people begin to drink at an early age, high levels of alcohol consumption during youth is more associated with influenced from peers and partners.

Associação da atividade física de lazer com o consumo de bebidas alcoólicas em adultos

&#x0D; &#x0D; &#x0D; Evidências mostram que atividade física (AF) pode se associar a níveis mais elevados de consumo de bebida alcóolica. Assim, esse estudo teve como objetivo verificar se existe ou não associação do nível de AF de lazer com o consumo de bebida alcóolica entre adultos de ambos os sexos. Dados secundários foram coletados do Ministério da Saúde (Vigitel) referente ao inquérito transversal realizado no ano de 2014, na cidade de Curitiba, PR, Brasil. A AF foi a variável de exposição e o consumo de bebida alcoólica a variável de desfecho. Participaram do estudo 1.504 adultos, sendo 557 homens com idade média de 51,7 ±18,6 anos e 947 mulheres com idade média de 55,7 ± 16,9 anos. O nível de AF foi categorizado em inativo e ativo e o consumo de bebida alcóolica em regular e abusivo. Os resultados foram controlados por sexo, idade e escolaridade. Os adultos ativos tiveram risco pelo menos 1,5 vezes maior (Razão de Prevalência (RP)= 1,5; IC95%: 1,2–1,9) para o consumo regular de bebida alcoólica e pelo menos 1,3 vezes maior (RP= 1,3; IC95%: 0,8–2,1) para o consumo abusivo, quando comparado aos inativos. Os homens ativos tiveram risco pelo menos 1,7 vezes maior (RP= 1,7; IC95%: 1,2–2,5) para o consumo regular e 2,3 vezes maior (RP= 2,3; IC95%: 0,9–5,7) para o consumo abusivo, enquanto mulheres ativas tiveram risco pelo menos 1,4 vezes maior (RP= 1,4; IC95%: 1,1–1,8) para o consumo regular e 0,9 vezes maior (RP= 0,9; IC95%: 0,6–1,7) para o consumo abusivo. Os resultados apoiam a existência de uma associação positiva incongruente entre o consumo de bebida alcoólica e a prática de AF.&#x0D; &#x0D; &#x0D;

Risk of pancreatic cancer and non-Hodgkin lymphoma associated with healthy lifestyle behaviors in the EPIC study

Introduction Pancreatic cancer (PC) and non-Hodgkin lymphoma (NHL) are both rare cancers which are particularly prevalent in Western countries and for which increasing incidence rates have been observed for the past decades. Moreover, both of them have unclear etiology and only few risk factors identified so far. While PC has been firmly associated with cigarette smoking, type II diabetes, obesity, as well as chronic pancreatitis, NHL has been mainly related to immune disorders and occupational exposure like benzenes. Roles of lifestyle factors in PC and NHL etiologies are still largely undefined, but recent evidences suggested that lifestyle, as well as high levels of alcohol consumption may be related to PC and NHL risks. Therefore, associations between modifiable lifestyle factors and either PC risk or NHL risk were investigated using an index expressing healthy lifestyle behaviors in the European Prospective Investigation into Cancer and Nutrition (EPIC) study. Methods Within 14 years of follow-up, 1113 incident PC cases and 2244 incident NHL cases (1845 B-NHL, 372 DLCBL, 415 CLL/SLL, 278 FL, and 535 PCN/MM) were diagnosed in the EPIC study. A score named the Healthy Lifestyle Index (HLI) ranging from 0 to 20 was built combining lifestyle factors assessed at baseline, i.e. a score for diet, physical activity, smoking habits, alcohol intake, and BMI. A score of 20 corresponding to the highest level of adherence to primary prevention recommendations was meant to reflect a healthy lifestyle. HLI was modelled in categories ( 15) and in continuous for a 1-category increase. Cox proportional hazard models with age as primary time variable were used to estimate PC and NHL hazard ratios (HR) and their 95% confidence intervals (95% CI) in relation to the HLI, adjusting for potential confounding factors. Results The combination of healthy lifestyle behaviors into an increasing HLI was inversely associated with PC with a 29% (95% CI: 0.64, 0.78) decreasing risk for a 1-category increase of HLI among EPIC participants. Modifiable lifestyle factors driving PC risk's reduction were smoking abstinence (pWald Conclusions Findings from the EPIC study suggested that the risk of PC was inversely associated with healthy lifestyle profiles, whereas no association was found in relation to NHL risk among EPIC participants. The results support adhering to primary prevention guidelines in order to decrease PC incidence and should encourage policy makers to promote healthy lifestyle in general population, in particular for cancers with no available screening strategy. In addition, they provide more evidence in favor of investigating non-modifiable risk factors to further understanding NHL's etiology.

Alcohol consumption, drinker identity, and quality of life among students: why there cannot be one prevention strategy for all

The objective for this study was to combine drinking characteristics and two subjective measures, drinker identity and alcohol-related quality of life, i.e., negative impact of alcohol on quality of life, to determine relevant profiles for indicated prevention programs. In particular, we hypothesized that different profiles of students with high level of alcohol consumption exist when exploring subjectivity. We performed an online survey among 16,930 students. We collected sociodemographics and environmental data, including alcohol-related quality of life, drinker identity, and drinking characteristics. We performed a hierarchical clustering on principal components. We described all variables in each cluster and explored between clusters differences by Kruskal-Wallis tests. We identified five clusters as regarding drinker identity, drinking characteristics, and alcohol-related quality of life. Among these five clusters, three clusters presented high drinking characteristics. A very vulnerable cluster showed high level of alcohol consumption, impact on quality of life and on academic results, and strong drinker identity. An egodystonic cluster showed high level of consumption, mild impact on quality of life and on academic results, but low drinker identity. A cluster seemed short-term super-adapted in heavy drinking environment, showing high level of alcohol consumption and drinker identity, but low impact on quality of life and on academic results (all between clusters p values < 0.001 with Kruskal-Wallis tests). The subjective experience of students from these clusters was significantly different (p value < 0.001), and could explain some inadequacy of certain prevention strategies, considering binge drinker student as a homogeneous group. Prospective studies are needed to explore changes over time of these clusters.

Individual differences in conditioned fear are associated with levels of adolescent/early adult alcohol consumption and instrumental extinction

Previous research has shown a relationship between alcohol exposure and conditioned fear, but the nature of this relationship remains unclear. We determined whether chronic intermittent access to alcohol during adolescence and early adulthood would alter or be associated with the level of conditioned fear to an auditory cue in male Long Evans rats. Rats received 6 weeks of chronic intermittent access to 20% alcohol or water from PND 26–66 and began behavioral testing 10 days later. We found no evidence that voluntary alcohol consumption altered fear. However, we found that rats that consumed more alcohol had lower fear, as measured with conditioned suppression of lever-pressing and conditioned freezing to an auditory cue. We have previously shown that higher levels of alcohol consumption are correlated with faster instrumental extinction learning. Therefore, we determined whether instrumental extinction would be directly associated with conditioned fear in rats never given alcohol access. As predicted, we found that rats that exhibited faster instrumental extinction also exhibited lower conditioned fear, as measured with conditioned suppression of lever-pressing and conditioned freezing. Our results suggest that at least part of the relationship between alcohol consumption levels and fear learning differences may be due to pre-existing individual differences. In addition, our finding that conditioned fear and instrumental extinction abilities (both separately associated with alcohol consumption levels) are associated with each other suggests that alcohol consumption levels may be a marker that can distinguish two separate phenotypes that encompass a wide variety of learning traits.

Diet and lifestyle habits: Association with cardiovascular disease indices in a Nigerian sub-population

BackgroundThere is inadequate evidence regarding the pattern of unhealthy lifestyle behaviours in Nigeria hence the aim of this study was to assess the pattern of lifestyle-related habits that predispose to risk of cardiovascular disease (CVD) indices in a Nigerian population. MethodsA population-based cross-sectional study was carried out on 422 apparently healthy males and females ≥18 years old. The World Health Organisation (WHO) STEPwise questionnaire was used to collect information on tobacco use or smoking habits, alcohol consumption and dietary habits. Logistic regression analysis was employed. Results22.8% and 30.2% of participants indicated that someone smoked in their home and/or in closed areas at workplace, respectively, in the past 30 days. 225/422 admitted to taking alcohol including 72% within the past 12 months. 52.8% of the participants consumed <5 servings of fruits and/or vegetables each day. Results further showed that participants with <5 servings of fruits and/or vegetables (OR: 1.06, CI: 1.01–1.13, p = 0.028) and high level of alcohol consumption (OR: 1.85, CI: 1.18–2.88, p = 0.007) were more likely to have hypertension. ConclusionsThe relatively high prevalence of alcohol consumption and apparent unhealthy diet are of huge concern given the increasing prevalence of CVD indices in the population.

Alcohol consumption externalities: An impact of alcohol policies on crime rates

Alcohol is traditionally considered by economists as an addictive good. Its consumption is often connected to irrational behaviours as well as negative external effects: growth of crime rates, traffic, occupational, and home accidents, fires. That is why most countries with high levels of alcohol consumption introduce special policy measures to reduce it and, as a result, its negative impact on society. In recent decade these policies were also adopted in Russia. This paper analyzes an impact of alcohol policy measures on crime rates. Empirical study is based on econometric analysis of panel data on Russian regions in 2003-2015. The results confirm effectiveness of temporal restrictions on alcohol sales in regard to juvenile and adult crime. Increasing price of vodka due to higher rates of excise tax reduces a number of crimes by teenagers. Meanwhile, price measures do not influence crime rates among adults.

Mental illness in Sweden (1896-1905) reflected through case records from a local general hospital.

Mental illness in a hospital in a medium-sized town in Sweden was studied. Consecutive case records from 1896 to 1905, and also from 2011, were selected. In the historical sample, neurasthenia was the most common diagnosis, followed by affective disorders and alcohol abuse. ICD-10 diagnoses corresponded well with the historical diagnoses. Melancholia resembled modern criteria for depression. Mania, insania simplex and paranoia indicated more severe illness. Abuse was more common among men and hysteria among women. Those with a medical certificate for mental hospital care were very ill and showed no gender difference. There were no diagnoses for abuse, but 17% had a high level of alcohol consumption. The pattern of signs and symptoms displayed by patients does not appear to change with time.

DENTAL AND SALIVARY STATUSES OF MEN WITH ALCOHOL USE DISORDER DEPENDING ON AGE

Introduction. High level of alcohol consumption in Russia and significant need of dental care especially among patients with alcohol use disorder (AUD) dictate necessity of investigation of dental pathology features among this group of patients. The aim of the study is to research dental and salivary statuses of men with ADS depending on the age. Methods. Examination of indices of dental and salivary statuses was carried out among two age groups of patients with second stage of AUD aged 25-44 years - «younger» and 45-64 years - «older». Methods of statistical analysis were Pearson's chi-squared test, Mann-Whitney U test and logistic regression. Results. In studied group median of DMFT with Q1 and Q3 is 14,0 (11,0-20,0) in younger group and 23,0 (18,0-29,0) in older group with significant prevalence of missing teeth in older group (p

Type D personality is associated with increased desire for alcohol in response to acute stress.

Type D personality (the combination of negative affectivity and social inhibition) is associated with high levels of alcohol consumption. We examined if Type D was associated with higher levels of alcohol use, and if Type D was associated with desire for alcohol in response to a social stressor. In an experimental study, participants (n=138) completed measures of Type D, stress, and alcohol use. They also took part in a stress-inducing public speaking task and provided measures of desire for alcohol at baseline, stressor, and recovery. Type D was associated with higher levels of alcohol use, stress, and desire for alcohol at stressor and recovery. Mixed measures analysis of variance demonstrated that there was a significant group effect of Type D (F(1, 136)=6.86, p<.05) and a significant time×Type D interaction (F(1.50, 204.49)=3.44, p<.05) on desire for alcohol. Type D individuals exhibited significantly higher levels of desire for alcohol during the stressor and recovery phases, compared to non-Type D individuals suggesting that Type D individuals may be motivated to consume alcohol in order to cope with stressful situations.