High Silver Content Research Articles

Dealloying and polydopamine/silver coating on NiTi alloy for improved antibacterial activity

Improved bone bonding ability and antibacterial activity are two critical requirements for implants. In this work, novel dual surface modifications of dealloying and polydopamine/silver coating on a NiTi alloy were conducted. Scanning electron microscopy (SEM) results show a porous layer with interconnected micro- and nano-pores on the dealloyed NiTi alloy. Fourier transform infrared (FTIR) and X-ray photoelectron spectroscopy (XPS) results confirm the formation of a polydopamine/silver coating on the surface of the dealloyed NiTi alloy. The silver nanoparticles (58.9 nm, in the polydopamine/silver coating) on the dealloyed NiTi alloy surface are smaller when compared with pristine NiTi alloy (73.1 nm). Moreover, the dealloyed NiTi alloy with polydopamine/silver coating exhibits better antibacterial activity against Escherichia coli (99.7%) and Staphylococcus aureus (99.4%) than pristine NiTi alloy with the same coating (97.3% and 96.5%, respectively), due to the larger surface area, higher silver content, and smaller silver nanoparticles that trigger more silver ion release. The combined dealloying and coating method is an effective way of increasing antibacterial activity of NiTi alloys. The findings presented in this work may provide a new guidance for the surface modification of NiTi implant materials.

Silver nanoparticle-modified melt-blown polypropylene: Antibacterial and antifungal properties and antiviral activity against SARS-CoV-2

Melt-blown polymer fiber materials are frequently used in the face mask manufacturing. In the present work, a melt-blown polypropylene tape was modified by silver nanoparticles using chemical metallization. The silver coatings on the fiber surface consisted of crystallites 4–14 nm in size. For the first time, these materials were comprehensively tested for antibacterial, antifungal and antiviral activity. The silver-modified materials showed antibacterial and antifungal activities, especially at high concentrations of silver, and were found to be efficient against the SARS-CoV-2 virus. The silver-modified fiber tape can be used in the face mask manufacturing and as an antimicrobial and antiviral component in filters of liquid and gaseous media.

Ligand Size and Carbon-Chain Length Study of Silver Carboxylates in Focused Electron-Beam-Induced Deposition.

Gas-assisted focused electron-beam-induced deposition is a versatile tool for the direct writing of complex-shaped nanostructures with unprecedented shape fidelity and resolution. While the technique is well-established for various materials, the direct electron beam writing of silver is still in its infancy. Here, we examine and compare five different silver carboxylates, three perfluorinated: [Ag2(µ-O2CCF3)2], [Ag2(µ-O2CC2F5)2], and [Ag2(µ-O2CC3F7)2], and two containing branched substituents: [Ag2(µ-O2CCMe2Et)2] and [Ag2(µ-O2CtBu)2], as potential precursors for focused electron-beam-induced deposition. All of the compounds show high sensitivity to electron dissociation and efficient dissociation of Ag-O bonds. The as-deposited materials have silver contents from 42 at.% to above 70 at.% and are composed of silver nano-crystals with impurities of carbon and fluorine between them. Precursors with the shortest carbon-fluorine chain ligands yield the highest silver contents. In addition, the deposited silver content depends on the balance of electron-induced ligand co-deposition and ligand desorption. For all of the tested compounds, low electron flux was related to high silver content. Our findings demonstrate that silver carboxylates constitute a promising group of precursors for gas-assisted focused electron beam writing of high silver content materials.

First Approach to Doping Silver into CrB2 Thin Films Deposited by DC/HiPIMS Technology in Terms of Mechanical and Tribological Properties

Doping of transition metal diborides (TMB2) films with soft metals (Ag, Au, Pt) can extend their application potential to tribological and biomedical fields. Here, a combination of direct current unbalanced magnetron sputtering (DC-UBMS) with high-power pulsed magnetron sputtering (HiPIMS) was used to synthesize silver-doped CrB2+x thin films on unheated substrates. All Ag–CrB2+x thin films were over-stoichiometric with a B/Cr ratio ranging from 2.05 to 2.30 and silver content varying from 3 at.% to 29 at.%. X-ray diffraction demonstrates the amorphous character of the structure in the case of films with silver content ranging from 0 at.% to 8 at.%. A nanocrystalline structure containing a cubic Ag phase is formed in the films with higher silver content. The highest hardness of 26.6 GPa accompanied by the highest value of elastic modulus of 362 GPa was measured in undoped CrB2.3 films. As the silver content in the Ag–CrB2+x thin films increases, the hardness and elastic modulus values gradually decrease to 7.8 GPa and 187 GPa, respectively. The friction properties of CrB2.3 films, expressed by the coefficient of friction against a steel ball of 0.72, are insufficient and limit their use in demanding industrial applications. However, silver doping significantly reduces the friction coefficient when the lowest value of 0.39 is measured in moderately hard Ag–CrB2+x films with an Ag content of 17 at.%. The scratch test shows satisfactory adhesion of films to substrates even without additional heating during deposition.

Study of Bond Formation in Ceramic and Composite Materials Ultrasonically Soldered with Bi-Ag-Mg-Type Solder.

This research aimed to study a Bi-Ag-Mg soldering alloy and the direct soldering of Al2O3 ceramics and Ni-SiC composites. Bi11Ag1Mg solder has a broad melting interval, which mainly depends on the silver and magnesium content. The solder starts to melt at a temperature of 264 °C. Full fusion terminates at a temperature of 380 °C. The microstructure of the solder is formed by a bismuth matrix. The matrix contains segregated silver crystals and an Ag (Mg, Bi) phase. The average tensile strength of solder is 26.7 MPa. The boundary of the Al2O3/Bi11Ag1Mg joint is formed by the reaction of magnesium, which segregates in the vicinity of a boundary with a ceramic substrate. The thickness of the high-Mg reaction layer at the interface with the ceramic material was approximately 2 μm. The bond at the boundary of the Bi11Ag1Mg/Ni-SiC joint was formed due to the high silver content. At the boundary, there were also high contents of Bi and Ni, which suggests that there is a NiBi3 phase. The average shear strength of the combined Al2O3/Ni-SiC joint with Bi11Ag1Mg solder is 27 MPa.

Provenance, depositional process, and tectonic setting of gold placer from the Bétaré-Oya Gold District (East-Cameroon, Central Africa) along the Precambrian Sanaga fault

The Bétaré-Oya Gold District is one of the three gold districts in East Cameroon with varied types of mining. The study site is an open-cast mine located in an alluvial plain. The strata succession globally consists of two positive sequences represented by three facies associations and seven lithofacies: massive clast-supported (Gcm), massive trough-cross bedded (Gtm), and massive matrix-supported (Gmm) conglomerates; massive sands (Sm); and massive (Fm), heterolothic (Fhl), and convolute and heterolithic (Fhlc) clays. The facies analysis indicates deposition after a recent tectonic event creating a depression, followed by a rapid deposition of varied facies and energies of sedimentation with fluvial and gravity inputs. The deposits come from proximal to distal sources but more proximal. The identified heavy mineral or accompanying minerals reveal a plutonic source (tourmaline sometimes folded), a volcanic source (olivine or clino-pyroxene with cracks), and a metamorphic source (sillimanite, andalusite, and staurolite). In the pan concentrates of placer with high silver (Ag) concentration (100 ppm) are also associated with relative abundance of lead (Pb) (17.8 ppm), zinc (Zn) (27 ppm), and low levels of copper (Cu) (3.1 ppm). The concentration and distribution of some element ratios, such as thorium/scandium (Th/Sc), chromium/thorium (Cr/Th), and europium anomaly (Eu/Eu∗), rare earth elements (REEs) and aluminum oxide/titanium dioxide (Al2O3/TiO2) vs. silicon dioxide (SiO2) plots for the studied sediment indicate heterogeneous sources of rocks with dominance of felsic sources. The discriminant diagram reveals a recycled or sedimentary provenance of the deposited sediments. The tectonic setting plot indicates a collision tectonic setting which is consistent with the Precambrian history of the study area which belongs to the Pan-African North-Equatorial fold Belt. The gold deposits in the Bétaré-Oya area probably derive from several sources, such as a vein source (from magmatic and metamorphic processes of the Neoproterozoic age) and a sedimentary source (from remobilization of ante-Neoproterozoic rocks of Archean and Paleoproterozoic age), deposited during the Cenozoic period linked to the reactivation of the Precambrian Sanaga fault. These are likely associated with a supergene source as indicated by the presence of dissolution microstructures. The cases of detrital gold deposits from several sources has been reported for the Serpont gold deposits in South-East Belgium, and those associated with authigenic forms are known in Poland, New Zealand, and Tanzania.

Recovery of pure silver from spent silver electroplating solutions via electrochemical process and zinc cementation

Recycling of spent silver electroplating solutions has been investigated via electrowinning and electrorefining in comparison to zinc cementation technique in this research. Two different compositions of transparent and dark waste solutions were used having the remaining silver contents of 17.71 g⸳L-1 and 33.36 g⸳L-1 respectively. The waste solutions were used as an electrolyte in the first step of electrowinning at low current density of 0.015 A⸳cm-2. It was found that increasing electrowinning time from 4 h to 24 h increased the recovery of silver cathode for both types of waste solutions. The optimum electrowinning time was higher than 8 h, giving the recovery of higher than 97.5% and 98.5% purity for 24 h electrowinning. Through the subsequent electrorefining, the electrowon silver cathode was set as the anode, while HNO3 + AgNO3 electrolyte containing high silver content of 120 g Ag/L was used. By controlling the potential at 0.8 V, silver crystal of high purity > 99.9% was obtained. The highest recovery was 99.11% when using silver cathode obtained from electrowinning of the transparent waste solution. Zinc cementation however led to loss of silver in the precipitate form on the zinc metal surface, giving only 86.16% recovery.

Silver Nanoparticles Capped with Poly[(maleic anhydride)-co-(vinyl acetate)

Anhydride containing functional co-polymer, Poly[(maleic anhydride)-co-(vinyl acetate)] (pMAVAc) was synthesized by free radical polymerization reaction presence of methyl ethyl ketone (MEK) media with benzoyl peroxide radical initiation at 80 ◦C. Surface modification of pMAVAc was carried out with silver to obtain size specific silver nanocomposites by well-known chemical-reduction approach. Structural characterizations of the samples were performed spectroscopic measurement and surface morphology identification using Attenuated Total Reflectance-Fourier Transform Infrared (ATR-FTIR) spectroscopy and Scanning Electron Microscopy (SEM), respectively. Results obtained from the ATR-FTIR analysis, detection of the characteristic spectrum data of the co-polymer composition in pMAVAc-AgNPs nanocomposite is proof that the co-polymer structure remains unchanged after treatment. The size and morphological properties of the silver nanoparticles were compatible with the characteristic nanomaterial structure and their average size was found to be 35 nm. In addition, as expected, MAVA-AgNPs nanocomposite, the detection of 79.73% Ag by mass is evidence of the high silver content in the material, and it was concluded that the co-polymer was successfully coated with silver. In recent years, considering the increasing importance of biocompatible nanomaterials in drug delivery systems and in pharmaceutical industry, the synthesized nanocomposites are thought to be a useful drug carrier system with potential antibacterial activity.

Nile Tilapia Skin Impregnated with Antibacterial Silver/Titanium Dioxide Compounds

The development of alternative (and free-of-antibiotics) antibacterial and antibiofilm agents is an important strategy to circumvent the resistance of bacteria to antibiotics. Herein, we explore the production of mixed oxides by incorporating silver nanoparticles in titanium dioxide as a silver concentration-dependent antibacterial agent that is further incorporated in Tilapia fish skin (a promising prototype of xenograft), integrating the antibacterial activity of mixed oxide into the intrinsic properties of Tilapia skin. The antibiofilm activity of samples prepared with high concentrations of silver (10 wt% of precursor AgNO3) has been considered a good antibiofilm response. The influence of silver content is also observed with respect to the minimum bactericidal concentration, which is reduced to 3.13 mg/mL with a characteristic kill time in the order of 30 min that is associated with antibiofilm activity in biofilm-forming strains of Staphylococcus aureus. These results indicate that modified Tilapia fish skin acquires antibacterial behavior and can be explored for xenografts with prospective applications in the light-dependent actuation of TiO2-based compounds.

Silver Nanoparticles Stabilized with a Chitosan Shell: Physical-Chemical Properties and Features of the Toxic Effect in Vivo

The results of investigating the in-vivo toxicity and safety of colloidal solutions of chitosan–silver nanocomposites with different concentrations of Ag (0.19, 1.9 mg/mL) obtained by the “green chemistry” technique via the chemical reduction of silver nitrate with chitosan under hydrothermal conditions are presented. The synthesized samples possess high aggregative stability (the values of their ζ potential are 37.3 ± 0.2 and 43.2 ± 2.5 mV) and pronounced antimicrobial properties against Staphylococcus aureus, Salmonella dublin, and Escherichia coli (inhibition zones of 11–16 mm). It is found that the nanocomposites are not very dangerous in the case of acute intragastric administration, are relatively safe in the case of intraperitoneal administration, and do not possess dermal irritation. A hydrosol of the nanocomposite with a high concentration of silver (1.9 mg/mL) induces reversible eye irritation in laboratory animals as well as has a pronounced sensitizing action, inducing the development of an allergy by the delayed hypersensitivity mechanism.

ВЛИЯНИЕ РЕЖИМОВ СИНТЕЗА НА ЭЛЕКТРОХИМИЧЕСКИЕ ХАРАКТЕРИСТИКИ КОМПОЗИТОВ НА ОСНОВЕ МНОГОСТЕННЫХ УГЛЕРОДНЫХ НАНОТРУБОК И ОКСИДА МАРГАНЦА, ЛЕГИРОВАННОГО ОКСИДОМ СЕРЕБРА

In this work, promising electrode materials for asymmetric supercapacitors based on multiwalled carbon nanotubes and manganese oxide doped with silver oxide were obtained and studied. To form the composites, the method of exposure of carbon material in an aqueous solution of potassium permanganate with the addition of silver nitrate in various quantities was used. It has been established that an increase in the amount of silver nitrate during the formation of the composite leads to an increase in the mass loading of the composite with both silver oxide and manganese oxide, which provides higher electrochemical characteristics of the material. The maximum specific capacity of the composite with a high content of manganese and silver was about 146 and 65 F/g at discharge current densities of 0.1 and 1.0 A/g, respectively. The high capacitive characteristics of the composite are ensured by a combination of the electrochemical activity of manganese oxide and the low electrical resistance of silver oxide.

Mordenite-Supported Ag+-Cu2+-Zn2+ Trimetallic System: A Variety of Nanospecies Obtained via Thermal Reduction in Hydrogen Followed by Cooling in an Air or Hydrogen Atmosphere.

Multimetallic systems, instead of monometallic systems, have been used to develop materials with diverse supported species to improve their catalytic, antimicrobial activity, etc., properties. The changes in the types of nanospecies obtained through the thermal reduction of ternary Ag+-Cu2+-Zn2+/mordenite systems in hydrogen, followed by their cooling in an air or hydrogen atmosphere, were studied. Such combinations of trimetallic systems with different metal content, variable ratios (between them), and alternating atmosphere types (during the cooling after reducing the samples in hydrogen at 350 °C) lead to diversity in the obtained copper and silver nanospecies. No reduction of Zn2+ was evidenced. A low silver content leads to the formation of reduced silver clusters, while the formation of nanoparticles of a bigger size takes place in the trimetallic samples with high silver content. The cooling of the reduced trimetallic samples in the air causes the oxidation of the obtained metallic clusters and silver and copper nanoparticles. In the case of copper, such conditions lead to the formation of mainly copper (II) oxide, while the silver nanospecies are converted mainly into clusters and nanoparticles. The zinc cations provoked changes in the mordenite matrix, which was associated with the formation of point oxygen defects in the mordenite structure and the formation of surface zinc oxide sub-nanoparticles in the samples cooled in the air.

Electron Beam Brazing of Titanium and Stainless Steel Dissimilar Joints with Ag-Based Filler

In this work, electron beam was used for butt brazing of austenitic stainless steel with grade 2 titanium. Due to its low solidus temperature and high silver content, AWS BAg-21 filler containing Ag, Cu, Sn and Ni was selected. The joints were brazed with a defocused oscillating beam using offset. The resulting brazed joints were subjected to static tensile testing, light microscopy, scanning electron microscopy (SEM), energy dispersive X-ray spectroscopy (EDS) analysis and hardness tests. By using appropriate parameters it was possible to reduce the phenomenon of diffusion of titanium atoms into the joint, which improved the properties of the obtained joints. The maximum tensile strength obtained was 244.2 MPa.

Impact of silver nanoparticle concentration in alginate microcapsules on their effects on morphological changes in periodontitis

Objective: to evaluate the effects of alginate microcapsules on morphological changes in periodontitis depending on silver nanoparticle concentration in them. Materials and Methods. The study was conducted on 30 rats distributed among three groups of 10 animals: the comparison group comprising animals with an experimental model of periodontitis and two experimental groups including animals with 5-week periodontitis, which were subjected to applications of the gel containing microcapsules with high (0.25 M, Group 1) and low (0.1 M, Group 2) concentrations of silver on the surface of their gums. To assess morphological changes, the mandible was sampled for subsequent examination. Results. In animals with periodontitis, changes in the supporting structure of the tooth took place, including defibration and perivascular edema in periodontal ligament of the tooth, and bone resorption via its replacement with connective tissue. The application of a gel containing microcapsules with silver nanoparticles led to a partial reduction of such disorders: particularly, it reduced bone resorption and its replacement with connective tissue. Destructive changes in periodontal tissues caused by gel with a high content of silver nanoparticles (0.25 M) were less pronounced than those caused by capsules with a low content of silver (0.1 M). Conclusion. Gels containing microcapsules with silver nanoparticles contributed to the reduction of destructive changes in the supporting structure of the tooth in periodontitis. The severity of the effects of the gel increased with an increase in the content of silver nanoparticles in alginate microcapsules.

Золото из аллювиальных отложений Пуйвинского района (Приполярный Урал)

In the Puyva region, located in the southeastern part of the Subpolar Urals, several gold-bearing placers and placer occurrences are known; however, information on gold itself is not complete enough, which makes the research relevant. The study of stream gold from the alluvium of the Khartes, Sertynya, Oika, Dorozhny, and Borovoy areas, has revealed that the gold is predominantly small; the particle shape is lamellar, thickened-lumpy, and complex. Gold roundness is medium; the portion of unrounded and well-rounded particles is insignificant. Silver is almost always present in gold, copper is less often noted. In some samples, electrum of a high silver content is found along with gold. Single gold particles have narrow, discontinuous high-fineness rims due to the removal of silver under exogenous conditions. Placer gold is gold of close wash-down; its original sources are probably represented by hydrothermal gold-sulfide-quartz veins localized in rocks of different composition and age.

Prenatal exposure to silver is associated with an elevated risk for neural tube defects: a case-control study.

Exposure to copper, silver, and titanium has been reported to be associated with a variety of adverse effects on humans, but it is little focused on the fetus. We investigated the associations between prenatal exposure to the three metals (copper, silver, and titanium) and risk for fetal neural tube defects (NTDs). Placental samples from 408 women with pregnancies affected by NTDs and 593 women with normal pregnancies were collected from 2003 to 2016 in Pingding, Xiyang, Shouyang, Taigu, and Zezhou counties of China. Multilevel mixed-effects logistic regression and Bayesian kernel machine regression (BKMR) were used to evaluate the single and joint effects of the metals on NTDs. Silver was associated with an increased risk for NTDs in a dose-response fashion in single-metal logistic regression, with adjusted odds ratios (95% confidence intervals) of 1.78 (1.04-3.06) and 1.92 (1.11-3.32) in the second and third tertiles, respectively, compared to the lowest tertile. BKMR revealed toxic effects of silver on NTDs and the association appeared to be linear. No interaction of silver with any of the other two metals was observed. Besides, silver concentration was positively correlated with maternal certain dietary intakes. Placental high silver concentrations are associated with an elevated risk for NTDs. Maternal diet may be a source of silver exposure.

Silver Depreciation in 3-Polker Coins Issued during 1619-1627 by Sigismund III Vasa King of Poland.

The present research is focused on the 3-Polker coins issued during 1619-1627 by Sigismund III Vasa, King of Poland. A major financial crisis took place at that time due to the 30-year War, which started in 1619. There are two theories among historians concerning the silver depreciation of these coins. The most common theory (generally accepted without proof) is that the later years of issue are depreciated below 60% Ag. The second theory is based on the medieval sources that indicate inflation during the years from 1621-1625, but the medieval source only refers to the inflation of the type of coins and does not mention the issuer. Therefore, in this study, we use modern investigation techniques and materials science methods to help historians elucidate the aforementioned aspects regarding the medieval period. The XRD investigation results are in good agreement with the SEM-EDX elemental analysis. The coins from 1619 and 1620 have high silver content, namely, 86.97% and 92.49%, which corresponds to good silver. The amount of Ag found in the coins from 1621-1625 issituated in the range of 63.2-74.6%. The silver titleis suddenly restored in 1626 at about 84.3% and is kept in a good range until the end of this decree under Sigismund III in 1627. In conclusion, the second theory was partly validated by our experimental results, certifying the currency depreciation during 1621-1625, but the silver title was not lower than 54.2%. Notably, even this depreciated silver title assures a good quality of the 3-Polker coins compared to similar coins issued in other countries that were copper-silver-plated. Therefore, the 3-Polker coins were preferably hoarded at that time.Small alterations in the mint mark's design were observed in all the depreciated coins compared to the good ones. This might be a sign for an expert to identify the depreciated coins, a fact which requires supplementary investigations. The silver title's restoration in 1626 also came with a complete change of the mintmark.

Silver Ions Incorporation into Nanofibers for Enhanced hMSC Viability

Antimicrobial properties of silver have been known for a long time, but there is also cytotoxicity of high concentrations of silver. Therefore, it is important to select the concentration and shape of silver depending on the goals. The ideal wound dressing should ensure that the wound remains optimally moist, protected from infections, has no toxic compounds, and stimulates regeneration. In the present work, we obtained a series of polycaprolactone-based nanomaterials fabricated by electrospinning and incorporated with silver ions (up to 0.6 at.%). By adjusting the magnetron current (0.3 A) and implanter voltage (5 kV), the deposition of TiO2 and Ag+ implantation into PCL/PEO nanofibers was optimized to achieve implantation of Ag+ without damaging the nanofibrous structure of the biodegradable nanofibers. The obtained results allow us to predict significant protection properties of the developed material not only from mechanical influence but also thanks to the antimicrobial effect due to silver ions, which is important for chronic wounds and injuries with a large area of damage and can activate host cells proliferation.

Physical and chemical properties of Ag–Cu composite electrical contacts prepared by cold-press and sintering of silver-coated copper powder

Effects of silver content (5–35 wt %), sintering temperature (150–850 °C), sintering time (30–180 min), and compaction pressure (200, 300, and 400 MPa) were studied on characteristics of prepared contacts. XRD (X-Ray Diffraction), OM (Optical Microscope), SEM (Scanning Electron Microscope), and electrical resistance analyses were used to study the properties of the contacts. The Results showed that increasing the percentage of silver in the contacts as well as increasing the time and temperature of the sintering process increase the oxidation of copper. It was found that galvanic corrosion and the Kirkendall effect between Cu and Ag (especially in high silver content) resulted in the formation of microvoids around the copper particles facilitating the copper oxidation. Apparent bulk density remained almost constant as the sintering temperature increased from 150 to 700 °C, while it dropped sharply in a sintering temperature of 750 and 800 °C. It was determined that increasing the sintering time from 30 to 60 min increases the apparent bulk density, while increasing the sintering time to more than 60 min reduces it. Moreover, increasing the amount of compaction pressure in 200–400 MPa did not affect the apparent bulk density. The electrical resistance is almost independent of sintering temperature in 25 °C–700 °C. Further change in sintering temperature from 700 to 750 °C raised the electrical resistance from 0.2 Ω to 15 kΩ. A Study of the electrical resistance of the samples indicated that increasing the Ag content up to 25 wt% reduces the electrical resistance. The electrical resistance of the sample containing 35 wt% Ag was 14 kΩ that which was higher than that of the sample containing 25 wt% Ag (0.11 Ω).

Laser induced nano-hole for high throughput fabrication of silver doped chalcogenide metasurfaces

We report the potential method for high throughput chalcogenide metasurface fabrication by using focused 632.8 nm laser induced nano-hole effect in the silver doped Ge28Sb12Se60 film. Generally, laser induced dewetting effect is hard to realize in thin Ge28Sb12Se60 films, however with the assistance of silver doping, the randomly distributed nano holes can be acquired in the dewetted region. The higher the silver concentration, the easier the laser induced nano-hole effect is, but much higher silver concentration like 47.8% will suppress the laser induced nano-hole effect due to the photocrystallisation. The nano holes can be enlarged and further connect with adjacent ones by increasing the output laser power, thus the morphology of the laser induced nano holes can be flexibly manipulated. Our findings are beneficial in high-throughput fabrication of chalcogenide metamaterial.