Maintenance Of High Quality Research Articles

Maintenance of high quality of life as an indicator of resilience during COVID-19 social distancing among community-dwelling older adults in Finland

PurposeSocial distancing during the COVID-19 pandemic reduced possibilities for activities of choice potentially threatening quality of life (QoL). We defined QoL resilience as maintaining high quality of life and studied whether walking speed, absence of loneliness, living arrangement, and stress-coping ability predict QoL resilience among older people.MethodsCommunity-dwelling 75-, 80-, and 85-year-old persons (n = 685) were interviewed and examined in 2017–2018 and were followed up during COVID-19 social distancing in 2020. We assessed QoL using the OPQOL-brief scale and set a cut-off for ‘constant high’ based on staying in the highest baseline quartile over the follow-up and categorized all others as having ‘low/moderate’. Perceived restrictiveness of the social distancing recommendations was examined with one item and was categorized as ‘yes’ or ‘no’ restrictiveness.ResultsBetter stress-coping ability (OR 1.21, 95% CI 1.14–1.28) and not being lonely (OR 2.67, 95% CI 1.48–4.63) increased the odds for constant high QoL from before to amid social distancing, and the odds did not differ according to the perceived restrictiveness of the social distancing recommendations. Higher walking speed predicted constant high QoL only among those perceiving restrictiveness (OR 1.16, 95% CI 1.07–1.27). Living arrangement did not predict constant high QoL.ConclusionDuring social distancing, psychosocial resources helped to maintain good QoL regardless how restrictive the social distancing recommendations were perceived to be. Better physical capacity was important for constant high QoL only among those perceiving restrictiveness presumably because it enabled replacing blocked activities with open outdoor physical activities.

Enhance Nurse Managers' Legal and Ethical Aspects at Benha University Hospital

Backgrounds: Nurse managers' are facing the challenges in their daily practice such as short ofstaffing, workload and maintenance of high quality and encounter many legal and ethical issuessurrounding these area. Law defined as a legal document setting rules governing a particular kind ofactivity while ethics are moral principles that govern how the person or a group will behave. Aim ofthe study: Was to enhance nurse managers' in the legal and ethical aspects at Benha UniversityHospital. Research design: A quasi-experimental design was utilized. Sample: Composed of 79nurse managers include nursing director (1), supervisors (14), and first line manager (64). Setting:The study was conducted in all units (44) at Benha University Hospital. Tools for data collectionTwo tools were used; the first tool: legal and ethical aspects knowledge questionnaire sheet. Thesecond tool: legal and ethical aspects observational checklist. Results: Majority of the studiedsample had unsatisfactory knowledge level about legal and ethical aspects at preprogram, whileimmediate post educational program the majority of them had satisfactory knowledge level. Also, theminority of the studied sample pre educational program demonstrated complete performance aboutlegal and ethical aspects, while post program the majority of them improved their performance.Additionally there was astatistical significant positive correlation between nurse managerg’s totalknowledge scores and performance scores. Conclusion: There were an improvement in level ofknowledge and performance of the nurse mangers about legal and ethical aspect immediately postand follow-up implementation of educational program compared to pre-program.Recommendations: Establish an ethical and legal committee within the organization for all ethicaland legal aspects in nursing practice. Further research: effect of legal and ethical nurses’ knowledgeon patients outcome.

EXPERT ASSESSMENT OF DEFECTS IN MEDICAL CARE IN SPINAL ANESTHESIA

The article presents the data of analysis, synthesis and generalization of the results obtained in the provision of medical care by anesthesiologists. It has been demonstrated that the issues of choosing the type of pain relief and the occurrence of possible complications, including those injured as a result of road traffic accidents, are given a lot of attention. It has been shown that there are cases of complications, including fatal ones, during or after anesthesia - spinal anesthesia. It was emphasized that in order to clarify the circumstances that are important for criminal proceedings to establish a causal relationship between the proper / improper performance by medical workers / anesthesiologist, their professional duties during the examination and treatment of patients, as well as the onset of severe consequences (including lethal), special knowledge, therefore, there is always a need for forensic medical examinations. When solving these issues, an analysis of medical documentation, synthesis and generalization of the data obtained is necessarily carried out, therefore, high-quality maintenance of medical documentation by anesthesiologists, which objectively reflects the methods of anesthesia and the patient's condition, is of great importance. It is emphasized that in the absence of both absolute and relative contraindications in patients for this type of anesthesia such as spinal anesthesia, anesthesiologists correctly choose both the drug itself and its dose, infusion with body fluid (to increase the volume of circulating blood), and the like. However, there have been cases when deaths occur as a result of correctly performed (both from the point of view of the technique and from the point of view of preliminary preventive measures) medical manipulation - spinal anesthesia, which leads to the development of a collapse with implementation in heart failure. Somatic diseases in patients (ischemic heart disease, hypertension, etc.) can contribute to the development and intensify the course of heart failure. However, there are no defects in the provision of medical care with which the onset of death of patients was in a causal relationship. In these cases, you can focus on the kind of death of patients - an accident.

The technology of striped catfish broodstock (Pangasius hypophthalmus) in high-quality maintenance

Striped catfish (P. hypophthalmus) is a high economic value and is a determining factor at the hatchery stage. Quality catfish brooders that can produce superior seeds can be obtained through good handling. The purpose of this study is to gain knowledge in the maintenance techniques of catfish broodstock. The working methods used in the study is a descriptive method with primary and secondary data collection. Striped catfish broodstock uses a recirculation system which includes preparation of pond maintenance, broodstock maintenance, feed management, water quality management, broodstock selection, and spawning. The results of the average water quality parameters for 25 days are turbidity 17.85 cm, temperature 29.51°C, DO 4.23 mg/L, ammonium 0.005 mg/L, and pH 7.54. The average weight measurements in the first and second sampling are 3.11 kg and 3.13 kg, while the average length measurements in the first and second sampling are 55 cm and 56.05 cm. The growth rate in the maintenance of catfish broodstock for 21 days is 9.52 grams/day, and the specific growth rate is 0.028%. Catfish spawning uses a ratio of ten males and three females.

QUALITY ENGINEERING TRANSFORMATION OVER THE YEARS AND ISSUES - A REVIEW

Traditional quality management and monitoring has been shown to be unsuccessful. Today, emerging companies are vying for more value to the consumer in order to ensure their maximum success and sustainability. Many businesses want to ensure that their goods and services are of high quality in order to attract customers. The current situation is implementing quality engineering solutions in industries. Quality engineering is the method of evaluating, handling, designing, and maintaining various systems in compliance with high standards. This method ensures that each stage of the product development cycle is subjected to a thorough inspection by quality engineers, reducing possible losses by eliminating defects from the start. Furthermore, highquality maintenance is important and should be made available for a long time after the product has been shipped. Customers' preferences are shifting significantly, necessitating improvements in design and production technology, which is becoming increasingly critical in satisfying individual customers. This necessitates paying particular attention to quality engineering. The paper starts with a review on quality emphasis over the last 37 years, quality concepts, and quality model evolution followed by i) a contrast of quality management and quality engineering, ii) developments in quality engineering tools and techniques, such as statistical process control (SPC), design of experiment (DoE), Taguchi processes, and quality function (QFD). This paper also looks at quality engineering-related problems. There are brief reviews of recent developments in well-known quality tools, such as statistical process control, quality function deployment, and design of experiment. The aim of this paper is to place quality engineering in context and emphasise its significance, as well as to present some issues at the frontiers of quality engineering.

Feasibility and efficiency of agricultural machinery maintenance

The greatest impact on machine uptime and performance is the timely and high-quality maintenance. The main contradiction is inherent in the system of maintenance and use of machines, in the coincidence of the timing of their performance: the more time is spent, the more maintenance operations need to be performed. As a result, during busy periods of fieldwork, to ensure high operating time, to the detriment of prevention, the mechanic has to virtually eliminate only the consequences of failures, which leads to their increase, machine productivity is reduced and operating costs increase. With the current trend of having more than one machine per operator, the operator is physically unable to perform all types of maintenance and repair work alone. Therefore, it would be advisable to transfer some of these works to specialized enterprises. The problem of increasing the reliability of tractors can also be solved by deeper specialization and intensification of maintenance operations during their transfer to nonstressed periods of fieldwork. In the work the structure of formation of technical service at the enterprises of agroindustrial complex is proposed and theoretically grounded. The main advantages of the proposed system of technical service are considered.

Results of implementation of a program of individual support of chemoradiation therapy in patients with head and neck tumors

The study objective is to improve quality of life in patients with oropharyngeal squamous-cell carcinoma during chemo/bioradiation therapy and at early stages after its completion which allows to perform the full extent of radiation within optimal treatment period.Materials and methods. A retrospective analysis of data on 196 patients who underwent chemoradiation therapy between 2005 and 2016 was performed. The results were used to develop and implement a program of support for chemo/bioradiotherapy. The program was characterized by: 1. use of Russian hydrogel materials for local delivery of antibiotics and wound-healing, anesthetizing, anti-inflammatory medications; 2. new regimens of pain relief with differentiated pathogenetic approach and use of modern transdermal long-acting forms; 3. nutritional support at every treatment stage; 4. assurance of compliancy. To evaluate the program, prospective randomized controlled study was performed between January of 2017 and March of 2019 including 60 patients.Results. Mucositis and dermatitis severity and changes in physical state associated with them, progression and duration of radiation did not significantly differ in the two groups. Use of the support program allowed to control adverse effects and to perform chemoradiotherapy to the full extent, at optimal time and with satisfactory quality of life.Conclusion. The program of support of chemo/bioradiotherapy in combination with psychological support is effective both form the point of view of optimization of treatment and rehabilitation times and from the point of view of maintenance of high quality of life in patients.

Acceptability of a community health worker intervention to improve the oral health of older Chinese Americans: A pilot study.

To evaluate the acceptability of a community health worker (CHW) intervention designed to improve the oral health of low-income, urban Chinese immigrant adults. Given that both dental caries and periodontitis are behaviourally mediated, biofilm-based diseases that are largely preventable with attention to regular oral hygiene practices and preventive dental visits, strategies to arrest or even heal carious lesions and high-quality maintenance care and plaque control without the need to resort to aerosol-generating surgical approaches are evidence-based best practices. Older immigrants have poorer oral health than older US-born natives, motivating the need for delivery of more effective and affordable services to this vulnerable population. CHWs were trained by the NYU College of Dentistry dental hygienist faculty members using dental models and flip charts to instruct patients on proper brushing and flossing techniques. In addition, they discussed the presented oral health promotion information one-on-one with patients, addressed any expressed concerns and encouraged prevention of oral conditions through regular dental visits and brushing with fluoride toothpaste. More than 98% of the 74 older Chinese adult participants strongly agreed/agreed that the CHWs helped them to improve how they take care of their health, the CHWs answered their questions and concerns, the information and topics were informative, and the in-person demonstrations were helpful in improving oral health. The health of all communities depends on access to comprehensive care, including oral health care, in the wake of COVID-19. CHW interventions are acceptable to and may reach marginalised and immigrant communities.

A Moroccan Leading Use Case for Predictive Maintenance, IoT and Industry 4.0

As part of our research, predictive maintenance is acquiring more attention through time, making it one of the most interesting topics and undeniable use cases when discussing advanced Industrial Internet of Things, Industrial Big Data and advanced data analytics combined with machine learning applications. Throughout the years, this new fresh market is expected to follow an alarming exponential growth trend with a 39% annual rate. The latter could only be achieved under the existence of well-structured organizations that aim to offer high quality maintenance monitoring and control through a combination of state-of-the-art tools and technologies. Whilst big players already exist in the market and managed to gain considerable attention in Industry 4.0, we cannot deny the exclusive establishment of startups and novel units operating in the same field of expertise. The aforementioned enterprises might be considered as freshmen and novices whilst being independent entities in the pool of enterprises, but we cannot ignore the fact that these micro-organizations were established by maintenance and reliability experts that have acquired a priceless know-how and expertise throughout the years. These startups offer robust and highly innovative hardware, software solutions in addition to a plethora of services for predictive maintenance, including platforms and analytics making them real players introducing a new competition in the market. OCP Maintenance Solutions is a newly-established situation created as a business unit to meet the internal maintenance needs of the OCP Group. The key objective and motivation behind establishing such service is to create a remote center of excellence in maintenance, based on wireless data collected combined with OCP’s expertise as a global player specialized in the mining, refining, processing, manufacturing, commercialization, marketing and development of phosphate rock, phosphoric acid and fertilizers. Today, the business unit established itself as an operational and independent unit providing sophisticated predictive maintenance services through a proprietary predictive analytics and IIoT-based platform in addition to multiple products and services including but not limited to: - Tailored digitalized desktop applications for maintenance and reliability - Training and e-learning solutions (i.e. development of bespoke serious games) - Out-of-the box and highly tailored mobile applications to serve diversified end-users and client’s needs

Long-term hospital management in the presence of COVID-19: A practical perspective

In December 2019, a novel pneumonia caused by a previously unknown pathogen emerged in Wuhan, China. Whereas, thus far, the large majority of people infected by SARS-CoV-2 develop mild inconsequential respiratory symptoms, a minority of mostly fragile, immunecompromised, often aged individuals with chronic medical conditions, develop a severe form of acute respiratory distress syndrome (ARDS) and shock leading to death. Thanks to the early implementation of a social distancing strategy, some regions have seen only a moderate but significant increase in the number of SARS-CoV-2 infection. Although, a significant increase in severe and critical COVID-19 patients was noted, requiring significant investment in dedicated personnel and allocation of specific hospitalization and intensive care unit (ICU) infrastructure and resources, but the medical systems’ functioning was not completely disrupted. As the development of a readily available vaccine against the new coronavirus is expected to take about 1.5 - 2 years, most hospitals will have to address the problems and challenges of caring for regular patients, some of them high-risk patients for SARS-CoV-2 infection, while caring in parallel for a low to moderate number of COVID-19 infected patients. This report presents an outline for a plan of action of a hospital system to deal with such an eventuality. We review the key changes that must be implemented in hospital management and activity to prevent disruption of key services due to the COVID-19 outbreak and the maintenance of high quality of care to all patients while ensuring the highest standards of staff and patient safety.

QUALITY OF MILK PRODUCTION OF THE HOLSTEIN COWS DEPENDING ON DIFFERENT FACTORS

Studies have revealed that despite the selection, the Holstein cows have a high genetic potential of milk production and in all lactations it is good in the specific conditions of the hot climate of Uzbekistan. The milk production level of German cows for the first lactation was 6511.2 kg of milk with a fat content of 3.84%, the Dutch — 6653.0 kg with fat content of 3.95%, and local breed — 6495.2 kg with a fat content of 3.95%. All mature cows retained high milk production, for III lactation and older it was 7112.5 kg and 3.90%, 7266.0 kg and 3.90%, 6847.5 kg and 3.94%, respectively. The yield of Dutch breeding cows was higher for 1 lactation by 141.80–157.8 kg, for III lactation and older by 153.5–418.5 kg, the yield of milk fat by 12.8–6.3 kg, respectively, of indicators peers of German and local selection. The cows of the studied selections combined well with high milk yield and fat content. The level of 4% milk for the studied lactation in all cows was quite high and testified to its good nutritional value. Holstein cows of different breeds are distinguished by a strong dairy type. For I lactation, for every 100 kg of live weight, 1,159.0–1265.5 kg of milk was produced, for III lactation and older - 1200.0–1308.6 kg. It is revealed that milk productivity depends on the level of live weight of cows. The increase in body weight of cows in all groups provides an increase in milk yield, milk fat yield, milk yield of 4% milk. Milk productivity is interrelated with the duration of the service period. In group I, cows with a service period of 91–100 days were more productive, in group II, 81–90 and in group III, up to 80 days. The use of Holstein cows for the production of milk is effective and ensures an increase in its production, the creation of highly productive dairy herds and the production of high-quality maintenance stock. KEYWORDS: Holstein breed, herd, milk yield, milk, fat, selection.

Long-term single-cell passaging of human iPSC fully supports pluripotency and high-efficient trilineage differentiation capacity.

Objectives:To establish a straightforward single-cell passaging cultivation method that enables high-quality maintenance of human induced pluripotent stem cells without the appearance of karyotypic abnormalities or loss of pluripotency.Methods:Cells were kept in culture for over 50 passages, following a structured chronogram of passage and monitoring cell growth by population doubling time calculation and cell confluence. Standard procedures for human induced pluripotent stem cells monitoring as embryonic body formation, karyotyping and pluripotency markers expression were evaluated in order to assess the cellular state in long-term culture. Cells that underwent these tests were then subjected to differentiation into keratinocytes, cardiomyocytes and definitive endoderm to evaluate its differentiation capacity.Results:Human induced pluripotent stem cells clones maintained its pluripotent capability as well as chromosomal integrity and were able to generate derivatives from the three germ layers at high passages by embryoid body formation and high-efficient direct differentiation into keratinocytes, cardiomyocytes and definitive endoderm.Conclusions:Our findings support the routine of human induced pluripotent stem cells single-cell passaging as a reliable procedure even after long-term cultivation, providing healthy human induced pluripotent stem cells to be used in drug discovery, toxicity, and disease modeling as well as for therapeutic approaches.

Optimization of overhaul of EMU Based on Planning Model

With the speed increase of the railway and the construction of the passenger dedicated line, the application efficiency and maintenance quality of the EMU, as the main means of transport of the passenger dedicated line, are directly related to the safe operation of the passenger dedicated line. Therefore, it is very necessary to carry out high-efficiency and high-quality maintenance work for EMU. In this paper, the maintenance problem of EMU is studied. According to the different maintenance process of EMU under different conditions, a mixed nonlinear programming model is established, and the software is used to solve the shortest total time of maintenance of all EMU is 541 min. The model provides a reference for the optimization of maintenance of EMU in actual production and life, and is helpful to improve the maintenance efficiency of EMU.

Structural and mechanical maintenance of quality of the rolled stock for cold upsetting of metal articles

A widely spread and most productive way to obtain finished metal articles with high structural and mechanical properties are methods of cold heading out of rolled metal, which must have a certain quality - the required plasticity, uniform structure and process parameters along the full length, as well as soundness. In conditions of fierce competition in order to improve the quality of the upset metal articles, the enterprises are forced to find reserves at all the points of the process chain for transformation of the original rolled metal. The greatest effect is achieved by the excluding of energy-consuming and labor-intensive annealing in protective gas furnaces and control of surface defects by etching or mechanical operations. This paper is presenting an economical and environment-friendly technology for structural and mechanical maintenance of high quality of rolled stock for upsetting of metal articles. The rolled steel prepared by this technology has a highly dispersed equally spaced structure without a decarburized layer with increased plasticity, which enables to reduce the number of transitions in the process of upsetting of metal articles and to increase the tools service life.

Improving maintenance quality in airport baggage handling operations

Purpose: The findings of a recent study at Heathrow are presented. The objective of the study was an operational quality issue with the baggage reclaim process and addressed the problem of unexpected downtime of baggage carousels during operational hours. For airlines and airports, the reclaim carousel is a key element in the process whereby passengers decide about the quality of their journey. Failure that leads to longer waiting times or even the relocation of baggage to another carousel results in passenger dissatisfaction and therefore needs to be avoided. The current regime of ‘time-based’ or ‘preventative’ maintenance can be classified as ‘run-to-break’ or ‘reactive’, causing frequent and costly downtime. A novel condition-based monitoring method to improve the reliability of the time-critical baggage reclaim process is described. Reclaim carousel maintenance quality was improved by the development of innovative condition-based maintenance systems designed to meet the requirements of twenty-first century airport systems and Industry 4.0 in cooperation with Siemens DF (digital factory) and their internet of things (IoT) platform Mindsphere. Methodology: A technical action research approach was undertaken at one of the biggest capital airport baggage handling systems in Europe. From June 2016 a condition monitoring pilot system on one operational carousel was established using engineering cycle theory. A solution was designed, installed, continually monitored and the results discussed with practitioners from the operation and maintenance (O&M) department. Root cause analysis was used to identify reasons for abrasive wear, followed by failure simulations during operation. Technical vibration data was collected so that an adequate condition monitoring system could be developed and optimised that improved the maintenance quality of reclaim carousels and reduced the costs associated with unexpected failure of the baggage handling system. Findings: Run-to-break maintenance is never conducive to quality maintenance and control and results in great uncertainty and unreliability. Meeting the objective of improving quality was difficult because the assets are hidden and baggage carousels are in constant use; however using wireless beacon technology it was possible to identify what problems might occur and when. Using the cloud-based IoT and Airport 4.0 also necessitated many sophisticated checks and measures, which are now in development. This study highlights the value of changing from the antiquated ‘run to break’ maintenance of hidden assets in airport baggage handling carousels to high-quality maintenance through the use of condition monitoring using wireless vibration sensors linked to a cloud-based IoT ecosystem. Originality/Value: With this solution in operation, maintenance quality has been approved and heavy damage can be avoided. The solution addresses problems caused by a variety of hidden equipment needing the highest possible maintenance quality. It can instantly secure the best quality of service for critical assets in an operation that cannot afford any unplanned downtime.

Upregulation of JHDM1D-AS1 protects PDLSCs from H2O2-induced apoptosis by decreasing DNAJC10 via phosphorylation of eIF2α

Periodontal ligament stem cells (PDLSCs) are a promising tool for regenerative medicine in clinical periodontal ligament repair. However, clinical maintenance of high quality and large quantity of PDLSCs faces multiple obstacles. One of them is how PDLSCs respond to environmental stimuli such as reactive oxygen species. We aim to elucidate how PDLSCs react to oxidative stress and the underlying mechanisms. We utilized hydrogen peroxide-induced oxidative stress to mimic ROS increase in rat PDLSCs. Our data indicated a rapid downregulation of a long non-coding RNA, lncRNA JHDM1D antisense 1 (JHDM1D-AS1), when PDLSCs were treated with hydrogen peroxide, which was negatively associated with PDLSC apoptosis. Moreover, our data showed that JHDM1D-AS1 regulated PDLSC apoptosis via inhibition of DNAJC10, a heat shock protein 40 family member. Moreover, overexpressed DNAJC10 inhibited Bcl-2 protein level and eIF2α phosphorylation level, which, in turn, contributed to PDLSC apoptosis. Our results revealed a protective role of JHDM1D-AS1 in ROS-induced apoptosis, and validated that JHDM1D-AS1/DNAJC10/phosphorylated-eIF2α/Bcl-2 pathway works as an anti-apoptotic signaling axis in PDLSCs.These findings will facilitate the in vitro culturing of PDLSCs for clinical usage and promote stem cell-based therapy for periodontal tissue regeneration.

Method of Gravity-Flowing Sewage Network Drainage as a Way to Increase its Durability and Maintainability

High-quality maintenance extends the service life of costly pass-through collectors. Maintenance of a collector requires its inspection and diagnostics, it is repaired if necessary. Thorough collector maintenance is possible only after its drainage. The most frequently used method of a collector drainage consists in its overlapping with plugs with further pumping of sewage via temporary branches, bypassing drainage rehabilitating sections. This method involves considerable technical and material difficulties and can be used mainly for drainage networks with diameter up to 400 mm. It also requires electrical energy to connect pumping units. This paper describes alternative methods of gravity sewage network drainage for the purposes of its inspection and repair, which provide high-quality maintenance of gravity sewer networks. These methods extend the network service life, as well as minimize the costs of diagnosis and repair works.

ОСОБЛИВОСТІ ВПРОВАДЖЕННЯ МІЖНАРОДНОГО СТАНДАРТУ ISO 50001 ДЛЯ ЗАБЕЗПЕЧЕННЯ ЕКОНОМІЧНОЇ СТАБІЛЬНОСТІ ЗАКЛАДІВ ВИЩОЇ ОСВІТИ В УКРАЇНІ

The paper offers the research findings on the implementation feasibility and specifics of internal energy management in the institutions of higher education (IHE) in Ukraine, based on ISO 50001 international standard requirements as a part of total management system within the government vector of energy saving economy framework. The emphasis is maid on exploring the overall effects on the economic position of institutions of higher education from the growing utility costs burden that influences the education high quality maintenance as well as university competitiveness on the higher education market. Rationale is provided on the validity and commonality of methods, approaches and techniques for the implementation of the internal energy management system in institutions of higher education according to the ISO 50001 standard together with demonstrating the simplicity of the given standard integration into the current management systems. It is argued that on the one hand, the implementation of energy management systems in institutions of higher education assumes certain financial investment and administrative and organizational changes, on the other, it lays the basis for attracting funding for capital projects on infrastructure modernization. The benefits of the new version of the ISO 50001: 2018 standard have been investigated, their tendency to switching to the area of service sector have been specified and the application of its basic approaches to enhance energy management systems of institutions of higher education has been proposed. The study employed the following empirical and theoretical methods: expert analysis (study on the benefits of the international standards ISO 50001 series implementation); systems and analytical (to justify the feasibility of using international standard approaches while making management decisions within IHE). The motivation behind the implementation of IHE integrated management systems based on the requirements of the international standards of the ISO 50001 series has been explored. From the semantic analysis perspective, in the context of the research subject area, a hypothesis about the need to expand the application of ISO 500001 energy management systems has been put forward. During the verification of this hypothesis a relationship between energy saving policy and the IHE economic security has been substantiated. It is argued that energy management system is an organic element in strategic management architecture which affects the competitiveness of IHE.

Modelling inspection and replacement quality for a protection system

An inspection and replacement policy for a protection system is described by a mathematical model that incorporates multiple aspects of maintenance quality. A three-state component failure model is assumed, with a defective state preceding failure. The quality of maintenance intervention is modelled by supposing that inspections may misclassify defects (false positives and false negatives) and further that an inspection may induce a defect. The quality of replacement is modelled by supposing that a component arises from a heterogeneous population, composed of weak and strong items and with the mixing parameter determining quality. Isolation valves used in water distribution systems motivate the model development, and a case study is considered in this context. We evaluate the impact of these aspects of the quality of maintenance upon cost and production losses. Defect induction is found to be a key determinant of the cost-optimal policy. The proposed model allows us to verify conditions that justify investment in higher quality maintenance, and thus to provide guidance for prioritization of this investment.

Ozone Therapy in Integrated Cancer Management

Cancer has become one of the most dreadful life style disease causing morbidity & mortality globally and India is topping the world. But the real fact is “Cancer is one of the most curable diseases in this world today”. In 2007 over 12 million new cases were diagnosed across the planet and approximately 7.6 million cancer deaths occurred. By 2050, these numbers will rise to an expected 27 million new cases and 17.5 million cancer deaths if our ability to prevent, diagnose and treat cancer does not improve. Cancer is already the leading cause of death in Canada, Australia, and it's number 2 in Great Britain. In 5 years cancer is expected to be the leading cause of death in USA. For more than 10 years we at Wellness Solutions have embraced rational cancer therapies proven both effective and minimally damaging to normal tissues and thus we have encouraged synergism between restorative therapies like Nutritional therapy, Ozone therapy and restrained Conventional Cancer therapy. We have found the best results in the combination of Personalized health assessment, Ozone therapy, parenteral nutrients, Oral nutrients & other Conventional management. We use simultaneous high dose of Vitamin C, Major Auto Haemo Therapy (MAHT) for more than hundreds of cases with much better results than any modes of conventional & alternate therapy. High doses of Vitamin C with Ozone therapy have given better results than any chemotherapy protocols. Dr. Otto Warburg (1931 - 1944) proposed the link between Oxygen & Cancer. Various researches have spent millions of dollars searching for causes of cancer and has reached nowhere. According to Dr. Warburg search for carcinogen is useless without correcting the oxygen deprivation. 60% deprivation of oxygen in a cell will cause stress leading to disturbance in oxidation/reduction and uncontrolled cell division. We have experiences in more than 100 cancer cases in the last two years. So, in integrated approach for cancer management Ozone therapy has a very prominent and decisive role for the maintenance of high quality of health & life.