It has long been known that stress has detrimental effects on cognition (e.g., Alderson & Novack, 2002; Lupien & Lepage, 2001), most notably documented for memory functions (e.g., Schwabe & Wolf, 2013). Interestingly, less is known about the effects of stress on other cognitive functions including language processing. Here, we have examined the effects of self-reported prolonged stress on recognition of emotional language content with a particular emphasis on gender differences. We tested how well 399 participants with different perceived stress levels recognized emotional voice cues. Findings confirm previous results from the emotional prosody literature by demonstrating that women generally outperform men in the vocal emotion recognition task. Crucially, results also revealed that medium levels of perceived stress impair the ability to detect sadness from voice cues in men but not women. These findings were not modulated by task demands (e.g., speeded response) or better acoustic discrimination abilities in women. Results are in line with the idea that perceived stress has a different impact on men versus women and that women have a higher level of experience in voice sadness recognition, potentially due to their predominant role as primary caretakers. (PsycInfo Database Record (c) 2024 APA, all rights reserved).