High Photothermal Conversion Efficiency Research Articles

The optical properties of nanorods with curved slots for solar photothermal conversion

Nanofluids are one of the keys to improving solar energy utilization efficiency. Metal nanoparticles (MNPs) have narrow-band absorption limitations in photothermal conversion. Recent studies have shown that it can overcome narrow-band absorption by adding slots on the nanoparticles (NPs) to improve photothermal conversion efficiency. In this work, we investigated the effect of curved slots on the optical properties of Ag nanorods by the finite element method. The results show that the presence of the curved slot enables the Ag nanorods to excite multiple resonance absorption peaks in the wavelength range of 300–1100 nm. The curved slotting reduces the overall scattering of the Ag nanorods and enhances its spectral absorption in the visible and near-infrared regions. In addition, we also calculated and compared the photothermal conversion efficiency of nanorods and nanorods with curved slots. At fv = 1 × 10−5 and h = 20 mm, the photothermal conversion efficiency of the curved slot Ag nanorods is increased by 6.8% over that of the Ag nanorods. In the measured volume fraction and fluid depth range, when the photothermal conversion efficiency reaches about 90%, the h and fv required for nanorods with curved slots are about 0.64 times that of nanorods. Nanorods with curved slots only need a meagre volume fraction and fluid depth to achieve high photothermal conversion efficiency. We believe that the proposed curved slot metal nanorods can provide a feasible solution for solving the narrow-band absorption of nanorods and improving the efficiency of solar energy utilization.

Cobalt Ferrite-Gossypol Coordination Nanoagents with High Photothermal Conversion Efficiency Sensitizing Chemotherapy against Bcl-2 to Induce Tumor Apoptosis.

Gossypol is a chemotherapeutic drug that can inhibit the anti-apoptotic protein Bcl-2, but the existing gossypol-related nanocarriers cannot well solve the problem of chemotherapy resistance. Based on the observation that gossypol becomes black upon Fe3+ coordination, it is hypothesized that encasing gossypol in glyceryl monooleate (GMO) and making it coordinate cobalt ferrite will not only improve its photothermal conversion efficiency (PCE) but also help it enter tumor cells. As the drug loading content and drug encapsulation efficiency of gossypol are 10.67% (w/w) and 96.20%, the PCE of cobalt ferrite rises from 14.71% to 36.00%. The synergistic therapeutic effect finally induces tumor apoptosis with a tumor inhibition rate of 96.56%, which is 2.99 and 1.47 times higher than chemotherapy or photothermal therapy (PTT) alone. PTT generated by the GMO nanocarriers under the irradiation of 808nm laser can weaken tumor hypoxia, thereby assisting gossypol to inhibit Bcl-2. In addition, the efficacy of nanocarriers is also evaluated through T2 -weighted magnetic resonance imaging. Observations of gossypol-induced apoptosis in tissue slices provide definitive proof of chemotherapy sensitization, indicating that such coordination nanocarriers can be used as an effective preclinical agent to enhance chemotherapy.

Copper-Zinc Bimetallic Single-Atom Catalysts with Localized Surface Plasmon Resonance-Enhanced Photothermal Effect and Catalytic Activity for Melanoma Treatment and Wound-Healing.

Nanomaterials with photothermal combined chemodynamic therapy (PTT-CDT) have attracted the attention of researchers owing to their excellent synergistic therapeutic effects on tumors. Thus, the preparation of multifunctional materials with higher photothermal conversion efficiency and catalytic activity can achieve better synergistic therapeutic effects for melanoma. In this study, a Cu-Zn bimetallic single-atom (Cu/PMCS) is constructed with augmented photothermal effect and catalytic activity due to the localized surface plasmon resonance (LSPR) effect. Density functional theory calculations confirmed that the enhanced photothermal effect of Cu/PMCS is due to the appearance of a new d-orbital transition with strong spin-orbit coupling and the induced LSPR. Additionally, Cu/PMCS exhibited increased catalytic activity in the Fenton-like reaction and glutathione depletion capacity, further enhanced by increased temperature and LSPR. Consequently, Cu/PMCS induced better synergistic anti-melanoma effects via PTT-CDT than PMCS in vitro and in vivo. Furthermore, compared with PMCS, Cu/PMCS killed bacteria more quickly and effectively, thus facilitating wound healing owing to the enhanced photothermal effect and slow release of Cu2+ . Cu/PMCS promoted cell migration and angiogenesis and upregulated the expression of related genes to accelerate wound healing. Cu/PMCS has potential applications in treating melanoma and repairing wounds with its antitumor, antibacterial, and wound-healing properties.

Fullerene Covalent Passivation of Black Phosphorus Nanosheets toward Enhanced Near-Infrared-II Photothermal Therapy

Photothermal therapy (PTT) triggered by near-infrared-II (NIR-II, 1000-1700 nm) light is developed as a potential tumor therapy technique with deeper tissue penetration capacity and higher allowable laser power density of the skin than NIR-I (750-1000 nm) biowindow. Black phosphorus (BP) with excellent biocompatibility and favorable biodegradability demonstrates promising applications in PTT but suffers from low ambient stability and limited photothermal conversion efficiency (PCE), and utilization of BP in NIR-II PTT is scarcely reported. Herein, we develop novel fullerene covalently modified few-layer BP nanosheets (BPNSs) with ∼9-layer thickness through an easy one-step esterification process (abbreviated BP-ester-C60), bringing about the dramatically enhanced ambient stability of BPNSs due to bonding of the hydrophobic C60 with high stability and the lone electron pair on the phosphorus atom. BP-ester-C60 is then applied as a photosensitizer in NIR-II PTT, delivering a much higher PCE than the pristine BPNSs. Under 1064 nm NIR-II laser irradiation, in vitro and in vivo antitumor studies reveal that BP-ester-C60 exhibits dramatically enhanced PTT efficacy with considerable biosafety relative to the pristine BPNSs. This is interpreted by the boost of NIR light absorption on account of the modulation of the band energy level resulting from intramolecular electron transfer from BPNSs to C60.

Construction of PEGylated chlorin e6@CuS-Pt theranostic nanoplatforms for nanozymes-enhanced photodynamic-photothermal therapy

Multifunctional nanoagents with photodynamic therapy (PDT) and photothermal therapy (PTT) functions have shown great promise for cancer treatment, while the design and synthesis of efficient nanoagents remain a challenge. To realize nanozyme-enhanced PDT-PTT combined therapy, herein we have synthesized the Ce6@CuS-Pt/PEG nanoplatforms as a model of efficient nanoagents. Hollow CuS nanospheres with an average diameter of ∼ 200 nm are first synthesized through vulcanization using Cu2O as the precursor. Subsequently, CuS nanospheres are surface-decorated with Pt nanoparticles (NPs) as nanozyme via an in-situ reduction route, followed by modifying the DSPE-PEG5000 and loading the photosensitizer Chlorin e6 (Ce6). The obtained Ce6@CuS-Pt/PEG NPs exhibit high photothermal conversion efficiency (43.08%), good singlet oxygen (1O2) generation ability, and good physiological stability. In addition, Ce6@CuS-Pt/PEG NPs show good catalytic performance due to the presence of Pt nanozyme, which can effectively convert H2O2 to O2 and significantly enhance the production of cytotoxic 1O2. When Ce6@CuS-Pt/PEG NPs dispersion is injected into mice, the tumors can be wholly suppressed owing to nanozyme-enhanced PDT-PTT combined therapy, providing better therapeutic effects compared to single-mode phototherapy. Thus, the present Ce6@CuS-Pt/PEG NPs can act as an efficient multifunctional nanoplatform for tumor therapy.

Mesoporous Silica-Encapsulated Gold Nanorods for Drug Delivery/Release and Two-Photon Excitation Fluorescence Imaging to Guide Synergistic Phototherapy and Chemotherapy.

Photothermal therapy is a promising light-based medical treatment that relies on light absorption agents converting light irradiation into localized heat to destroy cancer cells or other diseased tissues. It is critical to enhance the therapeutic effects of cancer cell ablation for their practical applications. This study reports a high-performance combinational therapy for ablating cancer cells, including both photothermal therapy and chemotherapy to improve therapeutic efficiency. The prepared AuNR@mSiO2 loading molecular Doxorubicin (Dox) assemblies were highlighted by merits of facile acquisition, great stability, easy endocytosis, and rapid drug release in addition to improved anticancer capability upon irradiation with a femtosecond pulsed near-infrared (NIR) laser, where AuNR@mSiO2 nanoparticles afforded a high photothermal conversion efficiency of 31.7%. Two-photon excitation fluorescence imaging was introduced into confocal laser scanning microscope multichannel imaging to track the drug location and cell position in real time for monitoring the process of drug delivery in killing human cervical cancer HeLa cells and then to realize imaging-guiding cancer treatment. These nanoparticles exhibit widespread potential in photoresponsive utilizations including photothermal therapy, chemotherapy, one- and two-photon excited fluorescence imaging, and 3D fluorescence imaging and cancer treatment.

NIR-II-absorbing diimmonium polymer agent achieves excellent photothermal therapy with induction of tumor immunogenic cell death

Photothermal therapy has shown great promise for cancer treatment and second near-infrared (NIR-II) -absorbing particles could further improve its precision and applicability due to its superior penetration depth and new imaging ability. Herein, high NIR-II-absorbing polymer particles were prepared by using soluble isobutyl-substituted diammonium borates (P-IDI). The P-IDI showed stronger absorption at 1000–1100 nm, which exhibited excellent photostability, strong photoacoustic imaging ability and high photothermal conversion efficiency (34.7%). The investigations in vitro and in vivo demonstrated that the excellent photothermal effect facilitated complete tumor ablation and also triggered immunogenic cell death in activation of the immune response. The high solubility and excellent photothermal conversion ability demonstrated that polymer IDI particles were promising theranostic agents for treatment of tumors with minor side effects.

Diradicaloid Strategy for High‐Efficiency Photothermal Conversion and High‐Sensitivity Detection of Near Infrared Light

AbstractOrganic molecules are promising near infrared (NIR) photothermal materials because of their structural flexibility and fine‐tuned properties. However, weak NIR absorption and strong fluorescence character lead to low photothermal conversion efficiency (PCE). Herein, NIR quinoidal diradicaloids are designed and synthesized by a heteroaromatic‐bridged Blatter radical strategy. Benefiting from the relatively planar framework and diradical character, these singlet diradicaloids exhibit strong and broad absorption in the NIR region (750–1100 nm) in both solution and aggregate states, which do not show any fluorescence. High PCE up to 71.4% is evaluated under 808 nm laser. On this basis, a NIR detector employing a blend of the diradicaloids and conductive ionic liquid is fabricated, yielding a remarkably high thermal response of 1100% at 0.5 W cm−2. This work reveals that π‐conjugated diradicaloids are promising candidates for NIR detection.

Experimental investigation of an asymmetric compound parabolic concentrator–based direct absorption solar collector using plasmonic nanofluids

Plasmonic nanofluid-based direct absorption solar collector (DASC) systems have shown a better perspective over surface-based solar thermalcollectors. These nanofluids demonstrated high thermal performance in photo-thermal conversion efficiency even at minute concentration compared to other testednanofluids. However, very few studies have been reported so farwith real-time outdoor experiments to show the opportunities and challenges in the practical applications of concentrating DASC systems. For the work presented here, an asymmetric compound parabolic concentrator (ACPC)-based DASC system has been designed, fabricated, and tested using mono-spherical gold and silver nanoparticle-based plasmonicnanofluids over several clear sky days at Jalandhar city (31.32° N, 75.57° E), India. The optical and morphological properties of synthesized nanoparticles were studied using UV-Vis spectrophotometry and High-resolution transmission electron microscopy (HR-TEM). Photo-thermal conversion tests were conducted using different working fluids and compared with a flat DASC system under similar operating conditions. The experimental results revealed that ACPC-based DASC system reached a maximum thermal efficiency of around 70% using plasmonic nanofluids which was approximately 28% higher than a flat DASC system with water as the working fluid. The stability analysis showed that plasmonic nanofluids are capable of retaining their optical properties even after several hours of sun exposure. The present study highlights the use of plasmonic nanostructures for achieving high photo-thermal conversion efficiency in concentrating DASC systems.

Investigation of utilizing carbonized lotus root as photothermal material in the solar steam generation system

ABSTRACT It is well-known that the shortage of water resources is one of the most serious global challenges. Steam generation via the solar system is one of the effective alternative ways that received significant interest in the last years to obtain clean water. Photothermal materials have received particular interest in this field; however, they suffer drawbacks, mainly high cost and poor energy efficiency, durability, and salt resistance. In this study, we selected carbonized lotus root as an alternative cheap photothermal material-hydrophilic functional groups with complete and abundant channels via freeze-drying technology. The carbonized lotus root has been prepared at different temperatures, and its ability in steam production has been investigated. The steam generation from seawater and with various NaCl added ratios has been examined via a solar simulator. The results showed that carbonized lotus root prepared at 900°C has a three-dimensional porous structure, high photothermal conversion efficiency, and evaporation performance in seawater and salt solution. The water evaporation rates for pure water, 1.4% NaCl, and 4.1% NaCl solutions are 0.90, 0.85, and 0.83 kg m−2 h−1, respectively. The ratio of the photothermal conversion is 61.3%, 58%, and 56% under 1 kW m−2 illumination. It has a certain guiding significance for the subsequent practical application.

Synthesized acrylate monomers to improve photothermal conversion efficiency and fire safety of PEG/black phosphorus (BP) phase change composites

The combination of photothermal components and phase change materials (PCMs) has received extensive attention. However, the incorporation of photothermal functionality into PCMs confronts the fatal problems of low utilization efficiency and performance compromise during processing. In this work, an acrylate monomer-passivation strategy was proposed to wrap photosensitive black phosphorus nanosheets (CG-BPs) to retain their intrinsic properties for high photothermal conversion efficiency. In addition, a flame-retardant acrylate (MCBDB) was further synthesized to crosslink with CG-BPs and build a framework for PEG1000 encapsulation. The resulting composite (cPCMs-1.2) was able to achieve a photothermal conversion efficiency of 85.3% even with a low content of CG-BPs (1.2 wt%) and unconcentrated irradiation. And benefiting from the synergistic flame-retardancy of CG-BPs and poly(MCBDB), the PCM composites displayed a reduced peak heat release rate of 38.7% compared with that of pristine PEG1000, indicating improved fire resistance. Considering its appropriate phase-change temperature, the application demonstration of the fabricated cPCMs-1.2 for human body hot compress was conducted, in which the promoting effect on blood circulation was observed. This work provides us with a new idea for the simple fabrication and new application of photothermal PCM with high photothermal conversion efficiency and application safety.

An oxygen-carrying and lysosome-targeting BODIPY derivative for NIR bioimaging and enhanced multimodal therapy against hypoxic tumors.

Cancer treatment modalities have gradually shifted from monotherapies to multimodal therapies. It is still a challenge to develop a synergistic chemo-phototherapy system with relieving tumor hypoxia, specific targeting, and real-time fluorescence tracking. In this study, we designed a multifunctional BODIPY derivative, FBD-M, for synergistic chemo-phototherapy against hypoxic tumors. FBD-M was composed of four parts: 1) The BODIPY fluorophore selected as a theranostic core, 2) A pentafluorobenzene group modified on meso-BODIPY to carry oxygen, 3) A morpholine group hooked to one side of BODIPY served as a lysosome-targeting unit for enhancing antitumor effect, and 4) An aromatic nitrogen mustard group introduced on other side of BODIPY to achieve chemotherapy. After introducing the morpholine and aromatic nitrogen mustard in BODIPY, the conjugate system of BODIPY was also expanded to realize near-infrared (NIR) phototherapy. Finally, FBD-M was obtained by a rational design, which possessed with NIR absorbance and emission, photosensitive activity, oxygen-carrying capability for relieving tumor hypoxia, high photothermal conversion efficiency, good photostability, lysosome targeting, low toxicity, and synergistic chemo-phototherapy against hypoxic tumors. FBD-M had been successfully applied for anticancer in vitro and in vivo. Our study demonstrates that FBD-M can serve as an ideal multifunctional theranostic agents.

An inorganic-organic-polymeric nanovehicle for targeting delivery of doxorubicin: Rational assembly, pH-stimulus release, and dual hyperthermia/chemotherapy of hepatocellular carcinoma.

Efficiently synergistic therapy of hepatocellular carcinoma (HCC) by chemotherapeutic drug and photothermal agent remains a considerable challenge. Here, we report a nanodrug that integrates specific hepatoma-targeted delivery, pH-triggered drug release, and cooperative photothermal-chemotherapy function. By grafting the easily self-assembled CuS@polydopamine (CuS@PDA) nanocapsulation with polyacrylic acid (PAA), an inorganic-organic-polymeric hybrid nanovehicle was developed as a dual photothermal agent and carrier for loading antitumor drug-doxorubicin (DOX) through electrostatic adsorption and chemical linking antibody against GPC3 commonly overexpressed in HCC, resulting in the nanodrug, CuS@PDA/PAA/DOX/GPC3. The multifunctional nanovehicle had excellent biocompatibility, stability, and high photothermal conversion efficiency, due to the rationally designed binary CuS@PDA photothermal agent. The 72-h accumulative drug release in pH5.5 tumor microenvironment can reach up to 84%, far higher than 15% measured in pH7.4 condition. Notably, in contrast to the merely 20% survival rate of H9c2 and HL-7702 cells exposed to free DOX, their viabilities in the nanodrug circumstance can maintain 54% and 66%, respectively, suggesting the abated toxicity to the normal cell lines. When exposed to the hepatoma-targeting nanodrug, the viability of HepG2 cells was found to be 36%, which further drastically declined to 10% plus 808-nm NIR irradiation. Moreover, the nanodrug is potent to cause tumor ablation in HCC-modeled mice, and the therapeutic efficacy can be greatly enhanced under NIR stimulus. Histology analyses reveal that the nanodrug can effectively alleviate the chemical damage to heart and liver, as compared to free DOX. This work thus offers a facile strategy for design of targeting anti-HCC nanodrug toward combined photothermal-chemotherapy.

Renal Clearable Catalytic 2D Au–Porphyrin Coordination Polymer Augmented Photothermal‐Gas Synergistic Cancer Therapy (Small 14/2023)

Photothermal-Gas Synergistic Cancer Therapy In article number 2206749, Benhui Hu, Yun Liu, and co-workers propose a cascade reaction-promoted CO release strategy to realize augmented photothermal-gas synergistic cancer therapy. Gold-based porphyrinic coordination polymer nanosheets synthesized by a simple aqueous phase reaction, with ultrasmall zero-valent gold as the coordination node, have the advantages of high drug loading capacity, high photothermal conversion efficiency and high catalytic activity. Furthermore, it has good biological safety and can be easily degraded and excreted through the kidney after treatment.

BODIPY-Based Multifunctional Nanoparticles for Dual Mode Imaging-Guided Tumor Photothermal and Photodynamic Therapy.

Multifunctional nanoparticles integrating accurate multi-diagnosis and efficient therapy hold great prospects in tumor theranostics. However, it is still a challenging task to develop multifunctional nanoparticles for imaging-guided effective eradication of tumors. Herein, we developed a near-infrared (NIR) organic agent Aza/I-BDP by coupling 2,6-diiodo-dipyrromethene (2,6-diiodo-BODIPY) with aza-boron-dipyrromethene (Aza-BODIPY). Through encapsulating with an amphiphilic biocompatible copolymer DSPE-mPEG5000, well-distributed Aza/I-BDP nanoparticles (NPs) were developed, which exhibited high 1O2 generation, high photothermal conversion efficiency, and excellent photo-stability. Notably, coassembly of Aza/I-BDP and DSPE-mPEG5000 effectively inhibits H-aggregation of Aza/I-BDP in aqueous solution and enhances the brightness simultaneously up to 31-fold. More importantly, in vivo experiments demonstrated that Aza/I-BDP NPs might be used for NIR fluorescent and photoacoustic imaging-guided photodynamic and photothermal therapy.

Optical properties of hollow plasmonic nanopillars for efficient solar photothermal conversion

Plasmonic nanofluids, which have superior optical properties, provide a novel way to achieve efficient solar thermal utilization. Here, the optical properties and photothermal conversion performance of hollow nanopillar structures based on four plasmonic materials (Ag, Au, Cu, TiN) were investigated and compared with the corresponding solid nanopillar structures. Numerical results show that the most significant increase in photothermal conversion efficiency is the plasmonic nanofluid based on hollow Au nanopillars, with an increase of 34.14%. The underlying physical mechanism is that the local and propagating surface plasmon resonances are further promoted in the hollow structure. In contrast, the increase of the photothermal conversion efficiency is only 1.41% for the hollow TiN nanopillars. This is due to the fact that the solid TiN nanopillars already have a high photothermal conversion efficiency of 97.19%. Thus, we can consider the enhancement of the photothermal properties of the plasmonic nanofluid by the hollow structure, especially for precious metal materials with narrow-band absorption, such as Au and Ag. For plasmonic materials with intrinsic broad-spectrum absorption (TiN, Cu), the enhancement effect is not significant. It is believed that this work will provide theoretical guidance for high-performance direct absorption solar collectors.

Tumor microenvironment-responsive nanosystem achieves reactive oxygen species self-cycling after photothermal induction to enhance efficacy of antitumor therapy

Tumor microenvironment response and spatio-temporal targeting are promising strategies to combination therapy. By regulating the tumor microenvironment and realizing the precise targeted therapy, the antitumor efficacy can be significantly improved while maintaining low side effects. Therefore, in this study, a reactive oxygen species (ROS)-responsive nanosystem (MND-IR@RESV) was constructed. The MND-IR@RESV nanosystem could be accurately tracked and located due to its own fluorescence. Mitochondria-targeted nanosystem promoted the release of ROS and contributed to the apoptosis of cancer cells. The MND-IR@RESV responded significantly to ROS, which promoted the deep release of drugs. Furthermore, the system also possessed high photothermal conversion efficiency and photothermal stability, which could achieve spatio-temporal targeting of drugs and ensure the efficient tumor eradication ability of Chemo/Photothermal/Photodynamic (CT-PTT-PDT) combination therapy. Both in vitro and in vivo tests demonstrated the significant antitumor effect of the MND-IR@RESV. Importantly, the nanosystem had the advantages of low toxicity and few side effects that conventional CT lacks, indicating that the MND-IR@RESV holds great promise in future cancer treatment.

Machine learning assisted photothermal conversion efficiency prediction of anticancer photothermal agents

Photothermal therapy (PTT) is a minimally invasive and promisingly effective strategy for thermal ablation of tumors. There is an urgent need for the development of ideal organic photothermal agents (PTAs) with high photothermal conversion efficiency (PCE). Machine learning (ML)-assisted predictions of PCE could offer an efficient way for early screening of PTAs. Herein, 44 organic PTAs were collected from the literature as a dataset to establish a best-performed regression model by comparing different ML methods, in which R2, Pears, and RMSE were 0.761, 0.913, and 0.058, respectively. Then, the reliability of the model was further verified by predicting two newly designed PTAs. The double bond of tetraphenylethylene (TPE) was found to be an important substructure to enhance PCE by the Shapley additive explanations method. The results show that ML can provide a valuable tool for predicting PCE of PTAs, thus promoting the development of photothermal therapy for cancer.

End Group Nonplanarization Enhances Phototherapy Efficacy of A-D-A Fused-Ring Photosensitizer for Tumor Phototherapy.

Enhancing the phototherapy efficacy of organic photosensitizers through molecular design is a fascinating but challenging task. Herein, we propose a simple design strategy to first realize the generation of superoxide anion radical (O2•-) by A-D-A fused-ring photosensitizers. Through replacing one cyano group of traditional end group with an ester group, we designed a novel nonplanar end group (A unit) to synthesize a novel A-D-A photosensitizer F8CA. In a comparison with its counterpart F8CN with the traditional end group, F8CA displays more loose packing and larger spin-orbit coupling constants. The F8CA nanoparticles showed higher photodynamic activities with the generation capability of singlet oxygen (1O2), hydroxyl radical (•OH), and O2•-, while F8CN nanoparticles could only generate 1O2 and •OH. In addition, F8CA nanoparticles still remain high photothermal conversion efficiency (61%). As a result, F8CA nanoparticles perform well in hypoxia-tolerant tumor phototherapy. This study brings an effective design thought for A-D-A photosensitizers.

Janus biomass aerogel for Highly-Efficient steam Generation, Desalination, degradation of organics and water disinfection

Solar-driven water purification has been deemed as a cheap, green and renewable technology to mitigate water shortage and pollution. Herein, a biomass aerogel with hydrophilic-hydrophobic Janus structure has been prepared as solar water evaporator, which is achieved by partially modifying hydrothermal-treated loofah sponge (HLS) with reduced graphene oxide (rGO). It's a rare design philosophy that HLS serves as a substrate with large pores and hydrophilic properties to ensure continuous and effective water transport, and the hydrophobic layer with rGO modification guarantees good salt resistance in seawater desalination with high photothermal conversion efficiency. As a result, the obtained Janus aerogel, p-HLS@rGO-12, exhibits impressive solar-driven evaporation rates of 1.75 kg m-2h−1 and 1.54 kg m-2h−1 for pure water and seawater respectively, with good cycling stability in the evaporation process. Furthermore, p-HLS@rGO-12 also demonstrates outstanding photothermal degradation of rhodamine B (greater than98.8 % in 2 h) and sterilization of E. coli (nearly 100 % in 2 h). This work offers an unusual approach to achieve highly efficient solar-driven steam generation, seawater desalination, organic pollutant degradation, and water disinfection simultaneously. The prepared Janus biomass aerogel holds great potential application in the field of seawater desalination and wastewater purification.