Background and aim: Psychologists believe that paying attention to nurses' psychological health canincrease their motivation for conducting their duties while are at work . The aim of this study was todetermine the relationship between mental health of nurses and their motivation in doing their tasks inGanjavian Dezfool HospitalMethod and material his was a correlational study being done on Ganjavian Hospital's nurses in city ofDezfool (N=240). The data were collected via a questionnaire. Nurses' mental health was measured usingGHQ28 and their job motivation, by Herzberg motivation questionnaire. GHQ28 had four non-psychoticdimensions (1-Somatization, 2- Anxiety And Sleep Disorder, 3- Social Dysfunction, and Depression).with 7 questions within each dimension. Spearman correlation was used to test the research hypothesis of thisresearch.Findings: The findings revealed that the relationship between1. Mental health and Nurses Job motivation (p = 0/0001, r = - 0/279)2. Physical symptoms and Herzberg hygiene factor ( p < 0/01 , r = - 0/ 276 ) -3. Anxiety and sleep disorders , and Herzberg hygiene factor ( p < 0/01 , r = - 0/ 272 ) ,4. Social function disorder , and Herzberg hygiene factor ( p < 0/01 , r = - 0/ 377 ) ,5. Depression, and Herzberg hygiene factor ( p < 0/01 , r = - 0/ 227 ) ,6. Physical symptoms, and Herzberg motivational factor ( P < 0/01 , r < - 0/ 244 )7. Anxiety and sleep disorders, and Herzberg motivational factor ( p < 0/01 , r = - 0/ 233 )8. Social function disorder, and Herzberg motivational factor ( p < 0/01 , r = - 0/ 286 )9. Depression, and Herzberg motivational factor (p < 0/01, r = - 0/ 227) are significant.Conclusion: The scores of nurses' mental health and Job motivation are correlated in a positive way, thusinvesting on nurses' mental health potentially enhance nurses' job motivation at hospital.Keywords: Mental health, Nurse, Motivation, Hospital.