Herbal Drugs For Treatment Research Articles

Review On Synthetic Vs Herbal Drugs, Its Various Extraction Methods And Animal Models Related To Depression

Depression is a neuropsychiatric disorder The focus of the current review article is on the most recent antidepressants drugs , their mechanisms of action, their pathophysiology, their side effects, and the methods for preventing drug-induced toxicity. There is also a description of phytochemicals that have been found to have antidepressant effects. Widely used synthetic drugs are, i. tricyclic antidepression ii. Selective serotonin reuptake inhibitors iii. monoamine oxidase inhibitors, iv. Serotonin-Norepinephrine Reuptake Inhibitors (SNRI) It has been reported that most antidepressants have negative health effects. An account of phytochemicals found to be acting as antidepressant is also included. Their beneficial effects to the human body have been attributed to the presence of active phytochemical ingredients with some efficiency for disease treatment as well as for beauty and health enhancement. Public awareness on the adverse effects of synthetic chemical products also increased the demand for herbal products. Highly efficient herbal processing and extraction technologies have been developed to obtain the optimal amounts of active ingredients from herbs Soxhlet extraction, supercritical fluid extraction cold Maceration Extraction, steam distillation, Hot Water Extraction, microwave assisted extraction. This review focuses on recent findings regarding some of the most widely employed animal models used currently to predict antidepressant potential. Here we, studies the assessment behavioral test by using various animal models force swimming test, tail suspension Test, rotarod test. In that for study of synthetic and herbal drugs in treatment of depression. Their advantageous effects on the human body have been related to the existence of active phytochemical components that are effective in treating certain diseases as well as enhancing attractiveness and health. The demand for herbal items increased as a result of growing public knowledge of the negative consequences of synthetic chemical products.

Role of Herbal Drugs in Treatment of Dermatologic Disorders: A Review

Herbal cosmetics contain phytochemicals derived from various botanical sources to address nutrient deficiencies and improve human appearance. Natural beauty is God's gift; cosmetics help sustain and enhance human beauty and personality. Recently, herbal cosmetics have gained popularity due to their inherent suitability and usefulness and fewer adverse effects than synthetic products. In this article, we highlighted the advantages, types of herbal cosmetics, toxic effects, chemicals and adverse effects of synthetic cosmetics and herbs used for dermal care. Then, we surveyed to investigate the pattern of cosmetic usage in the daily lives of people, their awareness and practices regarding caution with cosmetic use, and common side effects associated with people during cosmetic usage.

Approach of Herbal Drugs in Treatment of Cardio Vascular Disease

Approach of Herbal Drugs in Treatment of Cardio Vascular Disease

Leishmanicidal activity of Artemisinin against cutaneous Leishmaniasis, in Vitro

Background: Cutaneous leishmaniasis (CL) is a neglected disease in tropical countries, including Iraq. Several studies have sought to examine chemotherapies for leishmaniasis treatment but most of them are of toxic and/or undesirable side effect, therefore, the need for investigating new fewer toxic therapies is essential.
 Aim of study: In this study, the cytotoxic effect of Artemisinin (ART), a novel herbal compound, was screened against the two forms, promastigotes and amastigotes, of the Iraqi isolate of Leishmania tropica, the causative agent of Baghdad boil.
 Material and methods: Different concentrations (1000, 500, 250, 125, 62.5, 31.25, 15.6 and 7.8) µM of Artemisinin were screened to investigate the leishmanicidal activity of the herbal compound against the two forms of the parasite along three times of follow up (24, 48, 72) hour using MTT cytotoxicity assay.
 Results: The results showed that growth rate and cell viability were significantly decreased at all studied concentrations. The IC50 was measured after 72 hours of follow up and was 2.625 µM and 2.636 µM for promastigotes and amastigotes, respectively.
 Conclusion: These findings approved the leishmanicidal efficacy of Artemisinin against the of L. tropica and can be further studied to screen its effectiveness in vivo for exploring a safer herbal drug for treatment of cutaneous leishmaniasis.

Nanotechnological approaches for the development of herbal drugs in treatment of diabetes mellitus – a critical review

Diabetes mellitus (DM) is a chronic illness that requires continuing medical care and patient self-management education to prevent acute complications and to reduce the risk of long-term complications. The number of people with diabetes is increasing due to population growth, ageing, urbanisation and increasing prevalence of obesity and physical inactivity. Apart from currently available therapeutic options, many herbal medicines have been recommended for the treatment of diabetes. Herbal drugs are prescribed widely because of their effectiveness, less side effects and relatively low cost. Several pharmacopoeias have provided parameters to maintain quality and standardise procedures in identification/authentication of herbal inputs and their products. Available literature related to folklore medicine used in the treatment of diabetes extended to nanoformulation of herbal drugs up to date was cited. The use of bioactive compounds leads to new hope to improve the life expectancy and health status of the population for the formulation of novel drugs. Recently, many studies have shown that nanotechnology has the potential to be used in different biological and medical applications, mainly as targeted drug delivery systems to minimise and delay the chronic effects of diabetes. Herein, the authors presented a thorough review of the available herbal medicines and the possibilities of developing their nanoformulations in the treatment of DM.

HERBAL DRUGS IN PEDIATRIC RHINOSINUSITS TREATMENT

The article referred to the use of herbal drugs in treatment of acute rhinosinusitis in children. Topical aspects of the etiology, pathogenesis, clinical manifestations and diagnosis of acute rhinosinusitis in children are disscussed. The advantages of application of herbal drugs in such pathology are discussed indications for these drugs and possible side effects. The results of research of the efficacy and safety of herbal drugs for the treatment and prevention of acute sinusitis in children are adduced .

Prevalence of using herbal drugs as anti-diabetic agents in Taif Area, Kingdom of Saudi Arabia

Objectives: To evaluate the frequency and prevalence of using herbal drugs in treatment of diabetes in Taif area, Kingdom of Saudi Arabia. Materials and Methods: Structured questionnaire was the main instrument used to collect information to evaluate the attitude of respondents towards use of herbal medicine. In all, 228 diabetic patients were subjected to this study from clinics in 3 major hospitals in Taif - KSA (King Faisal Hospital (KFH), King Abdul-Aziz Hospital (KASH), Alhada Armed Forces Hospital over a 4-month and 20-day period. Results: Out of the 228 diabetics, (24.6%) of those patients were using herbs, more than half of them 31 (55.4%) were males and half of them 28 (50%) and were aged 50 years and above. Interestingly, when exploring the commonly used herbs, a total of 20 different herbal names were reported to be used by the surveyed diabetics. The top four used herbs were fenugreek, nigella, myrrh and garlic with a frequency of 57.1, 44.6, 42.9 and 32.1%, respectively. Conclusion and recommendation: About one-fourth of diabetic patients in this study were using herbs and the most frequently used herbs were fenugreek, nigella, myrrh and garlic. Pharmacists should be referred for consultation regarding the use of herbal remedies. In addition, knowledge about herbal drugs should be updated to the pharmacists and physicians through continued scientific programs. Public awareness about herbal remedies should be considered to guide the public for the trusted and safe source of information when it is needed.

Anti-Inflammatory Effect and Chemical Composition of Bupleurum chinense and Bupleurum kaoi

Bupleurum species represent one of the most successful and widely used herbal drugs for treatment of many diseases over the past 2000 years. Bupleurum chinense (B. chinense) is officially listed in China and Bupleurum kaoi (B. kaoi) is the only indigenous Bupleurum plant in Taiwan. Therefore, the aim of our study is to investigate the chemical components, anti-inflammatory, and antioxidants of B. kaoi and B. chinense. We report highly sensitive and specific assay for anti-inflammatory with a TNF-α luciferase plasmid vector. In preliminary experiments, we found that B. kaoi have stronger anti-inflammatory effects than B. chinense. However, it was no significant difference in the free radical scavenging activities of B. kaoi and B. chinense. We also demonstrated that saikosaponins (SS) a, SSc and SSd are the major compounds of B. kaoi and B. chinense in thin layer chromatography (TLC) analysis. The SSa, SSc and SSd content in B. kaoi has been reported to be higher than that in B. chinense. We combined TLC chromatograms with hierarchical clustering analysis(HCA)to classify into B. chinense and B. kaoi. The major impact feature were Rf 0.58(SSd) and Rf 0.44(SSc) .Theses studies showed that TLC chromatograms with HCA could be as tool in to differentiation and identify different species of herbal medicine in the future.

CHILDHOOD COUGH — RATIONAL APPROACH TO TREATMENT

Questions of rational approach to treatment of childhood diseases accompanied by cough are discussed in this article. The author emphasized the necessity of taking into account special features of the disease, mechanisms of action of used drugs and their undesirable effects, as well as individual characteristics of a patient. High efficacy and safety of herbal drugs in treatment of respiratory disorders in children is shown. An algorithm of choice of drugs influencing on cough is offered.

Herbal medicine in Egypt

Herbal medicine in Egypt

Research Highlights

Research Highlights