The article proposes a methodology for experimental monitoring of a set of parameters of the chemical state of a biopolymer system of technical cannabis. Using sequential extraction techniques, the content of alpha-cellulose, pectin substances, hemicelluloses, acid insoluble lignin and other related compounds, including heavy metal ions, extraction substances, silicon oxide, in bast, bonfire and undirected hemp obtained from technical hemp trusts grown in Ivanovo Region, was determined. The influence of the soil factor on the biosynthesis of polymers and related substances of the bast and woody parts of the stem and on the destruction of plant tissues of hemp in the conditions of meadow vegetation has been traced. It has been established that the composition of hemp raw materials is influenced not only by the genetic nature of the plant, but also by the natural conditions of its cultivation and the peculiarities of the action of soil microflora in the processes of primary processing of the stem.