The barley crop (Hordeum sativum L.) for the Central Black Earth region of Russia is a promising area for producers of all types of ownership. Barley is a valuable universal crop rich in complete protein and starch. In Russia, up to 70 % of barley is used for feed purposes. The feed value of barley is higher than that of wheat and corn, since it has a more balanced amino acid composition of protein, especially lysine. The protein complex of barley contains more than 20 amino acids, 5 of which are essential. The purpose of the research was to investigate the yield and quality of spring barley grain depending on the eff ect of predecessors and mineral fertilizers under the conditions of the Central Black Earth region. The object of the study was the spring barley variety Knyazhich. The following predecessors were studied such as grain corn, sunfl ower, sugar beet and soybeans. The fertilizer application rates were such as N10P10K10, N30P30K30, N50P50K50 and N70P70K70. It was found that the highest yield of spring barley was obtained with sugar beet as a predecessor. Thus, with a low background of mineral nutrition N10P10K10 it was 3.84 t/ha, with an average N30P30K30 it was 4.87 t/ha, with a high N50P50K50 it was 5.48 t/ha and with an intensive N70P70K70 it was 5.33 t/ha. Thus, the analysis of the eff ectiveness of the studied predecessors and the application of mineral fertilizers under spring barley indicate that for the predecessors sugar beet and soybeans, mineral fertilizers in the dose of N50P50K50, the highest profi t of 30343.5 and 25747.1 rubles/ha and a high bioenergy coeffi cients of 4.84 and 4.51 were obtained.