Healthy Lifestyle Modifications Research Articles

Oxidative balance score as a useful predictive marker for new-onset type 2 diabetes mellitus in Korean adults aged 60 years or older: The Korean Genome and Epidemiologic Study–Health Examination (KoGES-HEXA) cohort

BackgroundThe oxidative balance score (OBS) is a comprehensive pro- and anti-oxidative marker for assessing the risk of various metabolic diseases and cancers. However, it is not well established whether OBS is related to type 2 diabetes mellitus (T2DM), particularly in elderly populations. Therefore, our objective was to investigate the longitudinal effect of OBS on T2DM in a large cohort of Korean adults aged 60 years and older. MethodsWe assessed the data for 3516 participants aged 60 years and older without diabetes mellitus from the Health Examinees cohort of the Korean Genome and Epidemiology Study. We classified the participants into three groups according to OBS tertiles. We prospectively assessed hazard ratios (HRs) with 95 % confidence intervals (CIs) for new-onset T2DM using multivariable Cox proportional-hazard regression models during the mean 3.5 years following the baseline survey. ResultsA total of 109 participants (3.1 %) developed T2DM during a mean follow-up of 3.5 years. The incidence rates per 1000 person-years were 11.73 for the lowest OBS tertile (T1), 8.19 for the second tertile (T2), and 6.23 for the highest tertile (T3). Adjusting for all confounding factors, compared with the referent T1, the HR (95 % CI) of new-onset T2DM was not significant in T2 (0.71 [0.47–1.07]) but was significant in T3 at (0.47 [0.30–0.75]) (p for trend = 0.002). ConclusionsThe study suggests that a OBS could serve as a valuable predictive marker for new-onset T2DM in older adults. Our study suggests that maintaining an appropriate body weight through healthy lifestyle modification has the potential to lower T2DM incidence in elderly. This implies that the OBS may be a useful tool for assessing the incidence of T2DM even in older individuals.

2023 Australian guideline for assessing and managing cardiovascular disease risk.

The 2023 Australian guideline for assessing and managing cardiovascular disease risk provides updated evidence-based recommendations for the clinical assessment and management of cardiovascular disease (CVD) risk for primary prevention. It includes the new Australian CVD risk calculator (Aus CVD Risk Calculator), based on an equation developed from a large New Zealand cohort study, customised and recalibrated for the Australian population. The new guideline replaces the 2012 guideline that recommended CVD risk assessment using the Framingham risk equation. The new guideline recommends CVD risk assessment in people without known CVD: all people aged 45-79 years, people with diabetes from 35 years, and First Nations people from 30 years. The new Aus CVD Risk Calculator should be used to estimate and categorise CVD risk into low (< 5% risk over five years), intermediate (5% to < 10% risk over five years) or high risk (≥ 10% over five years). The following reclassification factors may be applied to recategorise calculated risk to improve accuracy of risk prediction, particularly in individuals close to a risk threshold: Indigenous status/ethnicity, estimated glomerular filtration rate, urine albumin to creatinine ratio measurements, severe mental illness, coronary artery calcium score and family history of premature CVD. A variety of communication formats is available to communicateCVD risk to help enable shared decision making. Healthy lifestylemodification, including smoking cessation, nutrition, physical activity and limiting alcohol, is encouraged for all individuals. Blood pressure-lowering and lipid-modifying pharmacotherapies should be prescribed for high risk and considered for intermediate risk individuals, unless contraindicated or clinically inappropriate. Reassessment of CVD risk should be considered within five years for individuals at low risk and within two years for those with intermediate risk. Reassessment of CVD risk is not recommended for individuals at high risk. CHANGES IN ASSESSMENT AND MANAGEMENT AS A RESULT OF THE GUIDELINE: The updated guideline recommends assessment over a broader age range and uses the Aus CVD Risk Calculator, which replaces the previous Framingham-based equation. It incorporates new variables: social disadvantage, diabetes-specific risk markers, diagnosis of atrial fibrillation and use of blood pressure-lowering and lipid-modifying therapies. Reclassification factors are also a new addition. Updated risk categories and thresholds are based on the new AusCVD Risk Calculator. The proportion of the population in the high risk category (≥ 10% over five years) is likely to be broadly comparable to more than 15% risk from the Framingham-based equation. The full guideline and Aus CVD Risk Calculator can be accessed at www.cvdcheck.org.au.

To Study Knowledge Regarding Healthy Lifestyle Modifications in Middle-Aged Diabetic Population

Background: Lifestyle plays a significant role in helping patients with diabetes control their blood sugar levels. Understanding early complications to prevent further adverse effects from uncontrolled sugar levels and a worsening healthy lifestyle is a prerequisite to knowledge regarding healthy lifestyle modifications. Exercise therapy has long been recommended for use in the management and prevention of type 2 diabetes. Dietary habits play an important role in the control of blood glucose levels in diabetic patients. An increase in calorie intake leads to poor glycemic control. Stress levels can affect the increased glucose levels. Middle-aged adults are at increased risk of developing diabetes, and this population may benefit from targeted interventions to promote healthy lifestyle modifications. Therefore, a study is needed to assess the level of knowledge and awareness of middle-aged diabetic populations regarding healthy lifestyle modifications. Materials and Methods: A validated questionnaire was prepared on Google Forms and distributed among the diabetic population. Data was calculated automatically on Google spreadsheet. Results: Patients with diabetes exhibit little awareness of recommended lifestyle changes. A poor understanding of diabetes and its complications is demonstrated by 83.87 % of the population. 77.41% of persons have a poor understanding of dietary adjustments for diabetes. 86.02% of respondents exhibit insufficient awareness of physical exercise therapies for diabetes. 52.68% of people are unaware of how stress affects insulin secretion. Conclusion: According to the study’s findings, Given the early onset of diabetes problems, middle-aged diabetics have an increasing need for knowledge regarding appropriate lifestyle adjustments due to their higher risk of diabetes.

Women's reproductive risk score and healthy lifestyle modification in cardiovascular disease: Findings from the UK Biobank

Background and aimsReproductive risk factors are associated with increased risk of cardiovascular disease (CVD) in women. However, the combined effects of the composite reproductive risk factors on CVD are unknown. This study was performed to construct a reproductive risk score (RRS) to measure reproductive status, examine the association between RRS and CVD, and explore the modification effect of healthy lifestyle on the association in women in the UK Biobank cohort. MethodsThe RRS was constructed in 74,141 female participants with data about the items derived for the RRS in the UK Biobank. The RRS was derived from 17 baseline variables, all of which indicated women's reproductive health status. We defined four categories of RRS status: low-risk group (score 0–1); low-intermediate group (score 2–3); high-intermediate group (score 4–5); and high-risk group (score 6–13). We also constructed a healthy lifestyle score (HLS) with five related factors, and categorized into unhealthy lifestyle group (score: 0–1), intermediate lifestyle group (score: 2–3) and healthy lifestyle group (score: 4–5). ResultsEach point increase in the RRS was associated with a 22 % higher risk of CVD (adjusted hazard ratio (aHR): 1.22; 95 % confidence interval (CI): 1.16 to 1.28), 23 % higher risk of IHD (1.23; 1.17 to 1.31) and 19 % higher risk of stroke (1.19; 1.07 to 1.32). The percentage population-attribution risks (PAR%) were 16 % (95 % CI: 8 to 24) for CVD, 15 % (95 % CI: 6 to 24) for IHD and 18 % (95 % CI: 1 to 33) for stroke. A healthy lifestyle significantly attenuated RRS associations with the incidence of CVD and IHD. The attributable proportions due to additive interaction (p < 0.001) between RRS and HLS were 0.14 (95 % CI: 0.07 to 0.22) for CVD and 0.15 (95 % CI: 0.09 to 0.23) for IHD, respectively. ConclusionsHigh RRS was associated with increased risks of CVD, IHD and stroke in female participants in the UK Biobank. The early-stage identification of women with reproductive risk using synthesised indicators and appropriate healthy lifestyle interventions could be useful for the prevention of early CVD and the extension of healthy active life expectancy.

An Analysis of Cancer causing Substances and its Impact on Prevalence of Cancer Cases among General Population residing along Thamirabharani River Basin – Evidence based research

As water quality degradation worsens in many countries, economic growth is stunted, health conditions worsen, food production is reduced, and poverty is exacerbated. The aim is to study the quantified levels of carcinogens in the environment, according to IARC Classification such as Arsenic, Cadmium, Chromium, Nickel, Lead, Nitrite/Nitrate and Phosphates and its correlation with spurts of cancer cases across certain sites that lie along Thamirabharani river basin, Tamil Nadu, India. A Systematic literature review for cross-sectional studies that provided information about the groundwater quality was carried out using six databases, "Researchgate, PubMed, Elsevier science direct, Wiley Online Library, Medline and Springerlink" from 2005 to 2021. TNCRP 2021 was taken as a reference to analyze the percentage of all types of cancer cases reported in the districts that lie along the river basin. Quality assessment was done using Newcastle Ottawa Scale. The results show the presence of high concentration of carcinogens in the groundwater and sediments collected near the industries, agricultural land and municipal sewage yard. The significant association between exceeding of the permissible limit of various heavy metal elements and compounds and percentage of cancer cases at that particular site is established in this study. Oral findings commonly associated with chronic toxicity of carcinogenic heavy metals are listed which serves as an alarming signal to adapt to healthy lifestyle and dietary modifications as required.

The acceptability of lifestyle medicine for the treatment of mental illness: perspectives of people with and without lived experience of mental illness

ObjectiveWhile lifestyle medicine can be highly effective for treating a range of mental illnesses these approaches are grossly underutilised and have not been systematically implemented into health care systems. Understanding the acceptability of lifestyle medicine is a critical first step to remediate this. This study evaluated the acceptability of lifestyle medicine relative to pharmacotherapy and psychotherapy, and explore perspectives of people with and without lived experience of mental illness.MethodsSix hundred and forty-nine adult Australian residents (62.6% female; 53.6% with a lifetime diagnosis of mental illness) completed an online survey based on the Theoretical Framework of Acceptability assessing the acceptability of lifestyle medicine, pharmacotherapy and psychotherapy for treating mental illness.ResultsMost participants felt positive about lifestyle medicine (76.9%) and felt that such approaches aligned with their personal values (74.9%). They understood how lifestyle medicine worked (86.4%) and believed it would be effective (69.6%). Lived experience of mental illness was associated with greater perceived burden and lower self-efficacy to engage in lifestyle medicine activities (both p < 0.001). While there was a clear preference for psychotherapy and lifestyle medicine over pharmacotherapy, pharmacotherapy was perceived as least effortful (p < .001) and participants were least confident in their ability to engage in lifestyle medicine (p < 0.05).ConclusionThe findings indicate strong acceptability of lifestyle medicine for mental illness, a preference for non-pharmacological treatment approaches, and an understanding of the challenges associated with making long-term healthy lifestyle modifications amongst people who have lived experience of mental illness.

Effect Of 12 Weeks Yoga Training And 12 Weeks Detraining on Blood Pressure Subjects with Hypertension

Background: Hypertension, an early predictor of cardiovascular disease can be prevented by healthy lifestyle modification. Stress-induced disorders such as hypertension can be effectively managed with the holistic science of yoga. Objective: In hypertensive individuals who are receiving routine treatment, we investigated the effects of yoga training for 12 weeks and compare as well as analyze these parameters at the end of yoga training (12th week) and after 12 weeks of follow-up with hypertensive on regular treatment (non-yoga group). Materials and methods: The study involved randomly assigned 124 hypertensive subjects to either experimental or control groups where N=65, and the yoga groups where n=61 between age of 25 to 45 years were included. In both the yoga group and the control group, heart rates (HR), Systolic Blood Pressures (SBP), Diastolic Blood Pressures (DBP), Pulse Pressures (PP), Mean Arterial Pressures (MAPs), and mean arterial pressure products were recorded before, after, and during the study period. Results: The means of RPP, HR, PP, SBP, MAP and DBP of pre-post, and follow-up values of the control group were compared by RM ANOVA and also there was no significant difference were found that exists among the groups. The mean values in the test group of post-training and follow-up show a significant decrease when compared with pre-training values. There are a significant decrease in test group follow-up values and post-training compared with follow-up values of control group and post-training respectively. In test group follow-up values the significant increase is found when compared with the test group post-training. Conclusion: Yoga reduced HR, SBP, DBP, PP, MAP, and RPP in essential hypertension under resting conditions. Reduced Sympathetic Activity, Enhanced Vagal Modulation and the increased sensitivity of baroreflex might be responsible for the harmonization of autonomic cardiovascular rhythms. Detraining from yoga, on the other hand, did not result in an increase in blood pressure. In conclusion, the present study shows that regular practice in yoga is helpful in reducing the hypertension, and that deep rest keeps the body healthy.

Effect Of 12 Weeks Yoga Training And 12 Weeks Detraining on Heart Rate Variability on Subjects with Hypertension

Background: Healthy lifestyle modifications can prevent hypertension, an early predictor of cardiovascular disease. Yoga is an effective way to manage stress-induced disorders, such as hypertension. Objective: This study investigated the effects of yoga training on hypertensive individuals receiving routine treatment over a 12-week period, comparing and analyzing heart rate variability (HRV) parameters at and after the 12-week yoga training period (the 12th week) with hypertensives receiving routine treatment (the non-yoga group). Materials and methods: A total of 132 hypertensive subjects between the ages of 25 and 45 were randomly assigned to control or experimental groups (N=66), and 66 of these subjects were exposed to yoga therapy (N=66). Before, after, and during the study period, HRV parameters were obtained. Results: RM ANOVA was used to compare time domain and frequency domain parameters of HRV of the control group at pre, post, and detrain, and it was found that no significant difference existed between the groups. Test group mean values show a significant increase in time domain parameters compared with pre-training values after training. Test group post-training and detrain values significantly increased when compared to control group post-training and detrain values. Test group detrain values decreased significantly from post-training to test group detrain values. Conclusion: Yoga therapy increases the HRV values in essential hypertension at rest. An increase in vagal modulation, a reduction in sympathetic activity, and an increase in baroreflex sensitivity may be responsible for the harmonization of autonomic cardiovascular rhythms. The results of detraining from yoga did not result in an increase in HRV. As a result, the present study shows that regular yoga practice reduces hypertension, and deep rest keeps the body healthy.

Expression analysis of ABCA1 in type 2 diabetic Pakistani patients with and without dyslipidemia and correlation with glycemic index and lipid profile

Diabetes Mellitus type II, earlier considered as an endocrinological disorder is now more regarded as an inflammatory disorder along with lipid aberrations. It demands for regular monitoring, healthy dietary habits and lifestyle modification. This study was focused on gene expression of ATP binding cassette protein 1 (ABCA1) in diabetic dyslipidemia patients in comparison with control groups of only diabetics and healthy individuals. Blood samples and data were collected from recruited 390 patients who were further divided into three groups (130 each). Glycemic index and lipid profile was assessed. Delta Delta Ct method was used that revealed downregulation of the studied gene more in diabetic dyslipidemia patients as compared to only diabetics and healthy controls. The Ct values of ABCA1 were associated with glycemic index and lipid profile using Pearson’s correlation. A negative correlation with fasting blood sugar and a positive correlation with HbA1cwas observed in only diabetics group. While in diabetic dyslipidemia and normal healthy controls, a negative correlation was found with both. As far as the lipid profile is concerned a positive correlation was observed among only diabetics with whole lipid profile. In diabetics with dyslipidemia, a negative correlation with all parameters except the TAGs was observed. A positive correlation with all except HDL was observed in healthy controls. The Ct values and fold change were compared among diseased and healthy individuals by applying independent t test. The cycle threshold in only diabetics was p = 0.000018 and in diabetic dyslipdemia individuals was p = 0.00251 while fold change in only diabetics (p = 0.000230) and in diabetics with dyslipidemia (p = 0.001137) was observed to be as statistically significant.

Awareness Status of Stroke among the Students of Saraswati Multiple Campus: An Exploratory Study

Stroke is a cerebrovascular disease characterized as a medical emergency that occurs when a blockage ensues in the brain and the blood supply is interrupted or discontinued by any means. It is popularly categorized as Ischemic stroke, Intracranial Hemorrhage, and Subarachnoid Hemorrhage and is one of the leading cause of deaths worldwide. This research includes prevention techniques, treatment strategies, opinions, and the awareness status of respondents, sequentially including the citations of various researchers on the issue of stroke. The research explores stroke-associated factors and the awareness status among the students, who are currently pursuing the degree, Master of Arts in Sociology and English at Saraswati Multiple Campus, Tribhuvan University. Similarly, the number of respondents was 22, and the data was collected through a convenience sampling technique that demonstrates the opinions of the respondents. The researcher has used both qualitative and quantitative methods to analyze the data. The principal findings present that the respondents (40.91%) believes hypertension is the major factor in stroke, whereas respondents (54.5%) agrees that exercise and healthy lifestyle modification can reduce the risk factors. Correspondingly, the data concludes respondents (86.4%) takes the stroke patient to the hospital and shows the overall awareness status is satisfactory. Furthermore, the knowledge in the event of stroke contribution to the patient is strong and the respondents (77.3%) have stated that the stroke affects the brain, although they are not familiar with Cardiopulmonary Resuscitation (CPR) techniques if the patient is in unconscious condition having breathing problem. Finally, the research concludes that stroke awareness status is satisfactory among the respondents and prioritizes that stroke-related course books must be included at the University level of Social Sciences disciplines, whereby the proper information and knowledge spreads within the students. It improves on identifying the actual symptoms and also encourages the patient's early admission to the hospital, which helps to decrease disability and other impairments via conducting proper methods.

Ontology-Based Recommender System for Personalized Physical Exercise in Obesity Management

In Indonesia, obesity is a serious health issue, and rates have risen recently because of sedentary lifestyles and poor eating practices. We suggest a proactive self-care suggestion system specifically created for Indonesians who are dealing with obesity to address this problem. Our recommender system attempts to give customers individualized suggestions for healthy lifestyle modifications that will make it easier for them to manage their weight. Because social media is so widely used in Indonesia, we created our system as a Telegram Chatbot. Our system may provide personalized suggestions based on a particular gender, activity level, fat mass, and difficulty of exercise that are relevant to Indonesians by fusing the user's ontological profile with generic clinical guidelines and standards for the management of obesity. Ontologies with Semantic Web Rule Language (SWRL) were used in the development of our system since SWRL ontologies are thought to perform better. Evaluations carried out using case studies and expert verification illustrate the usefulness of our suggested method, and the validated result of 88.8 percent demonstrates that our system can deliver good suggestion results for the user.&#x0D;

Improved prognosis with integrated care management including early rhythm control and healthy lifestyle modification in patients with concurrent atrial fibrillation and diabetes mellitus

Abstract Funding Acknowledgements Type of funding sources: None. Background Patients with concurrent atrial fibrillation (AF) and diabetes mellitus (DM) [AF-DM] have a high risk of cardiovascular and diabetes-related complications, but are less engaged in a comprehensive treatment approach. Purpose We evaluated the association of early rhythm control (ERC), lifestyle modification (LSM), and a combination of ERC and LSM with cardiovascular or diabetes-related complication risk in patients with AF-DM. Methods From the National Health Information Database, 47,940 patients diagnosed with AF-DM in 2009–2016 were included. We defined ERC as rhythm control therapy within two years of AF diagnosis and LSM as adherence to ≥2 of the healthy behaviors among non-current smoking, non-drinking, and regular exercise. We compared the primary (ischemic stroke) and secondary (macro- and microvascular complications, glycemic emergency, and all-cause death) outcomes in four groups: non-ERC and non-LSM (group 1), LSM only (group 2), ERC only (group 3), and both ERC and LSM (group 4). Results Of total, 10,617 (22%), 26,730 (55.8%), 2,903 (6.1%), and 7,690 (16.0%) were classified into groups 1 to 4, in sequence. The mean duration from AF diagnosis to ERC was 25.6±75.5 days. During 4.0 (interquartile range: 2.5–6.2) years’ follow-up, groups 2 and 3 were associated with 23% and 33% lower risks of stroke than group 1, respectively. Group 4 was associated with the lowest risk of stroke: hazard ratio (HR) 0.58, 95% confidence interval (CI) 0.51–0.67, p&amp;lt;0.001. Regarding secondary outcomes, the lowest risks were also observed in group 4; macro- and microvascular complications, glycemic emergency, and all-cause death had HRs (95% CIs) of 0.63 (0.56–0.70), 0.88 (0.82–0.94), 0.72 (0.62–0.84), and 0.80 (0.73–0.87), respectively, all p&amp;lt;0.001. Conclusions For AF-DM patients, ERC and LSM exert a synergistic effect in preventing cardiovascular and diabetes-related complications with the greatest lowered risk of stroke. A comprehensive treatment approach should be pursued in AF-DM patients.

Role of Chitraka Kshara in Abhyantara Arshas - A Literary Review

The present sedentary lifestyle, irregular food intake, prolonged sitting or standing and psychological problems has affected quality of life. Hemorrhoids are one such disease which is co-related to Arshas. The change in lifestyle has caused increase in the prevalence of this disease. It may occur at any age but mostly seen in the age between 30-65 years. Incidence is equal in both the sexes. Prevention of this is done by healthy diet and lifestyle modifications. Arshas is an abnormal fleshy overgrowth in Guda which is caused due to Virudhaahara Sevana, Adhyashana, Uttkatukasana, Vegadharana, Sahajaani etc. leading to derangement of Tridosha. Treatment of Arshas is of 4 types and Kshara Karma is one among them. Kshara Karma is indicated where Arshas Ankura is Mridu, Prasruta, Avagada and Uchritha. Kshara is considered superior among Shastra and Anushastra due to its property of Chedana, Bhedana, Lekhana and Tridoshagna. Chitraka being mentioned in preparation of Kshara and has Arshohara, Lekhana, Krimighna property. Considering all these factors an effort is made to substantiate the role of Chitraka Kshara and its probable mode of action in Arshas.

Implementation of automated behavior metrics to evaluate voluntary wheel running effects on inflammatory-erosive arthritis and interstitial lung disease in TNF-Tg mice

BackgroundAlthough treatment options and algorithms for rheumatoid arthritis (RA) have improved remarkably in recent decades, there continues to be no definitive cure or pharmacologic intervention with reliable long-term efficacy. For this reason, the combination of medications and healthy lifestyle modifications are essential for controlling joint disease, and extra-articular manifestations of RA, such as interstitial lung disease (ILD) and other lung pathologies, which greatly impact morbidity and mortality. Generally, exercise has been deemed beneficial in RA patients, and both patients and clinicians are motivated to incorporate effective non-pharmacologic interventions. However, there are limited evidence-based and specific exercise regimens available to support engagement in such activities for RA patients. Here, we provided the continuous opportunity for exercise to mice and implemented automated recording and quantification of wheel running behavior. This allowed us to describe the associated effects on the progression of inflammatory-erosive arthritis and ILD in the tumor necrosis factor transgenic (TNF-Tg) mouse model of RA.MethodsWild-type (WT; males, n=9; females, n=9) and TNF-Tg (males, n=12; females, n=14) mice were singly housed with free access to a running wheel starting at 2 months until 5 to 5.5 months of age. Measures of running included distance, rate, length, and number of run bouts, which were derived from continuously recorded data streams collected automatically and in real-time. In vivo lung, ankle, and knee micro-computed tomography (micro-CT), along with terminal micro-CT and histology were performed to examine the association of running behaviors and disease progression relative to sedentary controls.ResultsTNF-Tg males and females exhibited significantly reduced running distance, rate, length, and number of run bouts compared to WT counterparts by 5 months of age (p<0.0001). Compared to sedentary controls, running males and females showed increased aerated lung volumes (p<0.05) that were positively correlated with running distance and rate in female mice (WT: Distance, ρ=0.705/rate, ρ=0.693 (p<0.01); TNF-Tg: ρ=0.380 (p=0.06)/ρ=0.403 (p<0.05)). Talus bone volumes were significantly reduced in running versus sedentary males and negatively correlated with running distance and rate in TNF-Tg mice (male: ρ=−903/ρ=−0.865; female: ρ=−0.614/ρ=−0.594 (p<0.001)). Histopathology validated the lung and ankle micro-CT findings.ConclusionsImplementation of automated wheel running behavior metrics allows for evaluation of longitudinal activity modifications hands-off and in real-time to relate with biomarkers of disease severity. Through such analysis, we determined that wheel running activity increases aerated lung volumes, but exacerbates inflammatory-erosive arthritis in TNF-Tg mice. To the end of a clinically relevant model, additional functional assessment of these outcomes and studies of pain behavior are warranted.

Effectiveness of Lifestyle Modification on Health-Related Quality of Life among Women with Polycystic Ovary Syndrome.

Polycystic Ovary Syndrome (PCOS) is the most common reproductive endocrine disorder, which affects approximately one in every five women at the age of reproduction. The first line of PCOS management is recommended to be lifestyle modification. This study aimed to evaluate the effectiveness of lifestyle modification on Health-Related Quality of Life (HRQoL) among women with PCOS. This quasi-experimental study was conducted on 124 women with PCOS recruited from the outpatient clinic at El-Takhassosy Obstetrics Hospital, Port-Said, Egypt, in 2021 and allocated to two groups; an educational group (n = 62) and a control group (n = 62). For data gathering, two tools were used; an interviewing questionnaire for assessing the demographic characteristics and a standardized HRQoL questionnaire. Healthy lifestyle modification educational sessions included nutritional guidelines for PCOS, physical exercise (walking for 30 min five times weekly), and instructions to relieve stress. The mean (SD) of HRQoL score was 97.52 (8.75) in the educational group higher than the control group 87.32 (18.68) at 3 months postintervention and at 6 months postintervention; it reached 106.74 (11.53) in the educational group and 89.47 (22.14) in the control group. They were statistically significant after intervention (3 and 6 months) between studied groups (after 3 months was t86,563 = 3.891, p < 0.001 and after 6 months was t91,826. Women with PCOS should receive structured education about lifestyle modification next to treatment to ensure improvement, particularly in patient-centered care.

Improved prognosis with integrated care management including early rhythm control and healthy lifestyle modification in patients with concurrent atrial fibrillation and diabetes mellitus: a nationwide cohort study

BackgroundPatients with concurrent atrial fibrillation (AF) and diabetes mellitus (DM) [AF-DM] have a high risk of cardiovascular and diabetes-related complications, but are less engaged in a comprehensive treatment approach. We evaluated the association of early rhythm control (ERC), lifestyle modification (LSM), and a combination of ERC and LSM with cardiovascular or diabetes-related complication risk in patients with AF-DM (type 2).MethodsFrom the National Health Information Database, 47,940 patients diagnosed with AF-DM in 2009–2016 were included. We defined ERC as rhythm control therapy within two years of AF diagnosis and LSM as adherence to ≥ 2 of the healthy behaviors among non-current smoking, non-drinking, and regular exercise. We compared the primary (ischemic stroke) and secondary (macro- and microvascular complications, glycemic emergency, and all-cause death) outcomes in four groups: non-ERC and non-LSM (group 1), LSM only (group 2), ERC only (group 3), and both ERC and LSM (group 4).ResultsOf total, 10,617 (22%), 26,730 (55.8%), 2,903 (6.1%), and 7,690 (16.0%) were classified into groups 1 to 4, in sequence. The mean duration from AF diagnosis to ERC was 25.6 ± 75.5 days. During 4.0 (interquartile range: 2.5–6.2) years’ follow-up, groups 2 and 3 were associated with 23% and 33% lower risks of stroke than group 1, respectively. Group 4 was associated with the lowest risk of stroke: hazard ratio (HR) 0.58, 95% confidence interval (CI) 0.51–0.67, p < 0.001. Regarding secondary outcomes, the lowest risks were also observed in group 4; macro- and microvascular complications, glycemic emergency, and all-cause death had HRs (95% CIs) of 0.63 (0.56–0.70), 0.88 (0.82–0.94), 0.72 (0.62–0.84), and 0.80 (0.73–0.87), respectively, all p < 0.001.ConclusionsFor AF-DM patients, ERC and LSM exert a synergistic effect in preventing cardiovascular and diabetes-related complications with the greatest lowered risk of stroke. A comprehensive treatment approach should be pursued in AF-DM patients.

Blood Sugar Controlled of Type 2 DM Patient by Acupuncture Treatment and Suo-Xi Healthy Life Style Modification: A Case Study of Suo-Xi Acupuncture Specialized Hospital in Bangladesh

Blood Sugar Controlled of Type 2 DM Patient by Acupuncture Treatment and Suo-Xi Healthy Life Style Modification: A Case Study of Suo-Xi Acupuncture Specialized Hospital in Bangladesh

Association between Sociodemographic Characteristics, Clinical Variables and Adherence Level on Lifestyle Modification among Patients with Coronary Artery Disease

Background: Coronary artery disease (CAD) is one of the leading causes of death worldwide and contributes to large numbers of hospitalizations. Non-communicable diseases are Malaysia’s leading cause of death, mainly due to cardiovascular disease, and the most significant contributor in terms of disability among Malaysians. Adherence to recommended healthy lifestyles is a secondary prevention strategy to reduce the risk of reinfarction and readmission among patients with CAD. Studies have shown that sociodemographic characteristics and clinical variables are associated with adherence to lifestyle modification. The study's objective is to assess the adherence level and association between sociodemographic data and adherence level to lifestyle modification among patients with coronary artery disease. Methods: A cross-sectional study was conducted among 113 patients diagnosed with coronary artery disease using a self-administered questionnaire in one of the government cardiac centres. Results: The study found that the adherence level to lifestyle modification was low 2.09(±0.19). The adherence to recommended healthy lifestyle modifications was found to be significantly associated with race, F(3,109)=17.14, p&lt;0.05. This study also indicated an association between adherence level to recommended lifestyle modification and the level of education F(2,110)=8.71, F(2,110)=8.71, p&lt;0.05 and monthly income F(2,110)=13.15, p&lt;0.05. There was a small but significant negative correlation between BMI and healthy diet intake, r(113)=-0.207, p&lt;0.05. Conclusion: It was recommended that sociodemographic characteristics and clinical variables be crucial for nurses to understand and appreciate their patients' adherence to lifestyle modification behaviors. This will help nurses be more aware and sensitive to sociodemographic characteristics when planning their patients pre-discharge education and successful treatment.

Promoting adherence to stroke secondary prevention behaviours by imparting behaviour change skills: protocol for a single-arm pilot trial of Living Well After Stroke

IntroductionSurvivors of stroke have an elevated risk of recurrent stroke. Prompt intervention to support healthy lifestyle modification following an initial stroke is crucial for effective secondary prevention of stroke. However,...

Effects of Diet and Lifestyle on Audio-Vestibular Dysfunction in the Elderly: A Literature Review.

The world's age-related health concerns continue to rise. Audio-vestibular disorders, such as hearing loss, tinnitus, and vertigo, are common complaints in the elderly and are associated with social and public health burdens. Various preventative measures can ease their impact, including healthy food consumption, nutritional supplementation, and lifestyle modification. We aim to provide a comprehensive summary of current possible strategies for preventing the age-related audio-vestibular dysfunction. A PubMed, Embase, and Cochrane review databases search was conducted to identify the relationship between diet, lifestyle, and audio-vestibular dysfunction. "Diet", "nutritional supplement", "lifestyle", "exercise", "physical activity", "tinnitus", "vertigo" and "age-related hearing loss" were used as keywords. Audio-vestibular dysfunction develops and progresses as a result of age-related inflammation and oxidative stress. Diets with anti-inflammatory and antioxidant effects have been proposed to alleviate this illness. A high-fat diet may induce oxidative stress and low protein intake is associated with hearing discomfort in the elderly. Increased carbohydrate and sugar intake positively correlate with the incidence of audio-vestibular dysfunction, whereas a Mediterranean-style diet can protect against the disease. Antioxidants in the form of vitamins A, C, and E; physical activity; good sleep quality; smoking cessation; moderate alcohol consumption; and avoiding noise exposure are also beneficial. Adequate diet or nutritional interventions with lifestyle modification may protect against developing audio-vestibular dysfunction in elderly individuals.