ABSTRACT This study was to assess the concentrations and dangers of heavy metal contamination in soil and food crops on farmlands around an alluvial gold mining site in Ghana. At the sites, 40 soil samples were obtained from ten randomly dug mini holes at depths of 0 to 40 cm as well as 12 cassavas which were analyzed for cadmium (Cd), lead (Pb), copper (Cu), and zinc (Zn). Concentrations of Cd (0.08 g/kg), Pb (0.44 mg/kg), Cu (0.27 mg/kg), and Zn (1.74 mg/kg) in the soil were found to be below the WHO/GEPA guidelines. The mean concentrations of Cd (0.65 mg/kg) and Pb (1.36 mg/kg) were beyond the WHO/GEPA stipulated limit except for Cu and Zn in food crops. Bioaccumulation factor > 1 was recorded for Cd and Zn, which implies possible health risks. Values for non-carcinogenic health risks in adults and children ranged from 0 to 0.002, with the ingestion route representing the highest contributor. Cancer risk assessments for the exposure routes were all above the US EPA tolerable range of 1.0 × 10−6 to 1 × 10−4, with Cd being the highest contributor to cancer risk. The results from this study indicate that the populace is at risk of potential health problems.