Health Protection Research Articles

COVID-19 in South Africa and the Containment of the Homeless, Drug, and Substance Users in Tshwane: A Gender Perspective

To curb the spread of the coronavirus disease of 2019 (COVID-19) in response to the national lockdown, the City of Tshwane, supported by law enforcement agencies, involuntarily rounded up all people experiencing homelessness. The group, comprising around 2,000 women, men, and children, was initially gathered at Caledonian stadium but subsequently ferried to emergency temporary male and female COVID-19 homeless containment shelters established across the City. While the rolling out of the COVID-19 emergency homeless shelters programme by the city was based on intentions of health protection, management challenges led to ongoing safety concerns. Adopting Bowers’s (2006) conflict and containment theory, this study investigates the relationship between conflict behaviours and containment measures within female and male COVID-19 temporary homeless shelters. Preliminary evidence from a mixed methods study suggests that male admission and drug and substance use increase the levels of conflict behaviours, and no association was found between an increase in security personnel and a reduction in conflict behaviours in COVID-19 shelters. A large proportion of conflict behaviours could be reduced by more efficient, effective, and improved service and by reducing the size of COVID-19 temporary homeless shelters, making the shelters less coercive and safer for residents and staff.

Contribution to the study of possible transport of PM10 aerosols in the eastern part of the Czech Republic

The article deals with the assessment of air pollution in the eastern regions of the Czech Republic: Moravia and Silesia, where the limits for the protection of human health for PM and benzo[a]pyrene are significantly exceeded, especially in the north-eastern area. The extent to which this heavily polluted part of Moravia and Silesia affects the central, southern and south-eastern parts of Moravia, i.e. south-eastern part of the Czech Republic, has often been discussed but not proven. The assessment demonstrated the influence and extent of pollutant transport by determining the prevailing daily wind direction. The prevailing NE wind direction results in worse dispersion conditions and higher PM10 concentrations throughout the study area. Conversely, the SW wind direction is a carrier of better dispersion conditions with lower PM10 concentrations in the area. The effect of transport of PM10 pollution in the daily type from the NE direction can be observed at those sites located in the NE of the area of interest from the border with Poland to the Prerov site. In the case of more southerly sites, the methodology used does not allow to determine whether and to what extent they are affected by pollution transport from the northeastern part of Moravia or from neighbouring Poland. This methodology is particularly useful when only 24-h pollutant concentrations are available (not at more detailed, e.g. 1-hour intervals). The internal methodology of the Czech Hydrometeorological Institutefor calculating back trajectories of wind from ground stations is particularly applicable for detecting the origin of short-term episodes with high pollutant concentrations.

1-Benzhydryl-piperazine: Isolation, structure determination, and in silico studies for a novel potential narcotic agent detected in sports supplements

Adulteration of sports supplements poses significant health risks, necessitating stringent regulatory oversight. This study investigates deceptive practices by manufacturers, including concealment of formulations and manipulation of label information, impacting a wide demographic beyond elite athletes. Cinnarizine (CIN), and its degradation product, 1-benzhydryl-piperazine (BHP), which has amphetamine-like effects, are detected for the first time in 8 out of 41 sports supplements. An HPTLC method was developed to quantify CIN, and validated with specificity, linearity, the limit of detection (LOD), the limit of quantification (LOQ), accuracy, and precision studies. The linear range was between 50–800 ng spot−1. LOD and LOQ were 15 and 50 ng spot−1, respectively. The average recovery was calculated as 88.32 %, and %RSD values were less than 4 %. CIN’s degradation products were detected using GC-MS. CIN's decomposition into BHP also was confirmed via NMR analysis. Molecular docking studies revealed BHP's superior binding affinity and stability compared to 1-benzyl-piperazine (BZP), a prohibited narcotic agent, for dopamine and serotonin receptors, indicating potent psychoactive effects. Molecular dynamics simulations further elucidated interaction patterns, highlighting BHP's robust binding and potential for abuse, necessitating regulatory scrutiny and potential reevaluation of its legal status. It is also the first in silico study to compare BHP with BZP in terms of receptor interactions, which makes it pioneering. This study emphasizes the critical need for regulatory vigilance in the sports supplement industry to ensure consumer safety. Methodologies developed here for detecting adulterants provide foundational tools for future research aimed at enhancing public health protections against adulterated supplements. Regulatory collaboration and enhanced quality controls are essential to mitigate risks associated with deceptive practices and ensure the well-being of consumers.

The Application of Hydrogen Sulfide Fluorescent Probe in Food Preservation, Detection and Evaluation.

This work primarily reviewed the response mechanism of fluorescent probes for H2S detection in foodstuffs in recent years, as well as the methodologies employed for detecting foodstuffs. Firstly, the significance of studying H2S gas as an important signaling molecule is introduced. Subsequently, a review of the response mechanism of the scientific community on how to detect H2S in foodstuffs samples by fluorescent probe technology is carried out. Secondly, the methods commonly used for detecting foodstuffs samples are discussed, including the test strip method and the spiking recovery methods. Nevertheless, despite the significant advancements in this field, there remain some research gaps. Finally, the article identifies the remaining issues that require further attention in current research and proposes avenues for future investigation. More importantly, this work identifies the current limitations of research in this field and proposes future applications of fluorescent probes for H2S in assessing food freshness and determining food spoilage. Therefore, this review will provide robust technical support for the protection of consumer health and the advancement of the sustainable development of the food industry and also put forward some new ideas and suggestions for future research.

Early warning COVID-19 outbreak in long-term care facilities using wastewater surveillance: correlation, prediction, and interaction with clinical and serological statuses

The unprecedented COVID-19 pandemic has highlighted the strategic value of wastewater-based surveillance (WBS) of SARS-CoV-2. This multisite 28-month-long study focused on WBS for older residents in 12long-term care facilities (LTCFs) in Edmonton (AB, Canada) by assessing relationships between COVID-19, WBS, and serostatus during the pandemic. Wastewater samples collected two to three times per week were tested for SARS-CoV-2 using RT-quantitative PCR. Theserostatus of antibodies was examined using immunoassays. The data of clinical COVID-19 outbreaks based on extensive testing were obtained from local public health officials. Analyses included calculating correlations between 7-day rolling averages for WBS and COVID-19 cases and investigating whether WBS led or lagged confirmed outbreaks using a multinomial test. Wastewater results correlated well with clinical COVID-19 infections and outbreaks at participating LTCFs. 1058 (36·0%) of 2936collected wastewater samples were SARS-CoV-2 positive, compared with 1247people (resident n=671, staff n=572, and unknown n=4) reporting positive test results of 21 673clinical samples assessed (5·8%). WBS led clinical testing in 32 (60·4%) confirmed outbreaks, which was significantly different from WBS lagged (12outbreaks [22·6%, 95% CI 11·3-33·7]). Non-detection of WBS SARS-CoV-2 served as a negative predictor for outbreaks. WBS results attested protective immunity in vaccinated individuals before the omicron wave. Aparallel increase in the proportions of positive WBS SARS-CoV-2 and anti-nucleocapsid antibodies underlined that omicron was an immunity-evading variant despite high seropositivity of neutralising antibodies after multiple doses of vaccine. Implementation of WBS could enable targeted clinical investigations and improve cost-effectiveness of COVID-19 outbreak management in LTCFs. WBS and serostatus provided informed dynamic changes of infections and immunity. Critical evidence was that LTCF WBS is an effective early warning system to support rapid public health outbreak management and protect vulnerable older populations. Canadian Immunity Task Force for COVID-19 and Alberta Health.

Assessment of the Demographic Burden of Epidemics and Diseases within the African Sub-Region: A Review of Recent Epidemiological Data, Responses, and Resultant Psychosocial Risk Tendencies

Background: Over the past few decades, epidemic outbreaks and disease occurrences have become more frequent and widespread in Africa, posing challenges for poor countries in the region and impacting vulnerable populations. Limited resources, inadequate healthcare infrastructure, socioeconomic inequalities, malnutrition, mass gatherings, and lack of proper sanitation and hygiene contribute to Africa’s high burden of epidemics and infectious diseases such as cholera, measles, monkeypox, Ebola viral disease, and COVID-19. This paper reviewed epidemic outbreaks and diseases transmitted through intimate contact in Africa and their impacts on vulnerable populations. Methods: A narrative review approach was adopted to gather and analyze the relevant literature on epidemic outbreaks in African sub-regions. The review encompassed causes, transmission patterns, demographic impact, community susceptibility, preventive measures, and psychosocial risk-taking behaviors. Results: This study emphasizes the importance of addressing the causes of response lapses and the resulting human, material, and economic losses in the region. Effective preventive measures include disease surveillance, early mitigation strategies, contact tracing, personal protective measures, improved political and public health leadership, and socioeconomic equity. However, the review highlights challenges in implementing these measures effectively due to limited resources, delayed detection, and difficulties in scaling up response solutions. Conclusions: There is a need for a comprehensive approach involving health departments, infrastructure development, and addressing socioeconomic factors.

Impact of Organochlorine Pesticides Exposure on Histone Modification H3K9ac: Implications for Unexplained Recurrent Miscarriage.

Epigenetic alterations, changes in gene expression without DNA sequence modifications, are associated with various health disorders, including reproductive health issues. These alterations can be influenced by environmental factors such as pesticides. This study aimed to explore the relationship between exposure to Organochlorine Pesticides (OClPs) and the histone modification mark H3K9ac in the placenta and fetal tissue, in the context of unexplained recurrent miscarriage (URM). In the case-control study, serum samples from 73 women with URM and 30 healthy women were examined for the presence of OClPs, which include 2,4-DDT, 2,4-DDE, 4,4-DDT, 4,4-DDE, α-HCH, β-HCH, and γ-HCH, using gas chromatography. Western blot analysis was used to assess H3K9ac expression in placental and fetal tissues. In the URM group, significant increases were observed in the values of α-HCH, β-HCH, 2,4-DDE, and 4,4-DDE, as well as in the concentration of total OClPs (Ʃ3HCH, Ʃ2DDE, Ʃ2DDT, and Ʃ7OClP), compared to controls. While H3K9ac levels in fetal tissue showed no significant difference, a notable decrease was found in the placental tissue of the URM. In the placenta tissue of URM, logistic regression analysis also revealed a significant inverse correlation between the toxins α-HCH, 2,4-DDE, 4,4-DDE, 4,4-DDT, total OClPs, and reduced H3K9ac expression. Our findings suggest that OClPs exposure may contribute to URM by reducing H3K9ac expression in the placenta, potentially affecting placental growth and immune tolerance. This underscores the need for further investigation into the involved mechanisms and potential therapeutic interventions, and the importance of OClPs regulation for reproductive health protection.

Are You the Outlier? Identifying Targets for Privacy Attacks on Health Datasets.

The identification of vulnerable records (targets) is an important step for many privacy attacks on protected health data. We implemented and evaluated three outlier metrics for detecting potential targets. Next, we assessed differences and similarities between the top-k targets suggested by the different methods and studied how susceptible those targets are to membership inference attacks on synthetic data. Our results suggest that there is no one-size-fits-all approach and that target selection methods should be chosen based on the type of attack that is to be performed.

The “Cycle” of HIV: Limits of Personal Responsibility in HIV Vulnerability Among Transgender Adolescents and Young Women in Lima, Peru

Globally, transgender women (TW) face a high burden of the HIV epidemic. In Peru, HIV prevalence among TW rises at age 25, indicating a need to understand HIV vulnerability as adolescents reach adulthood. The life course of TW is often marked by abuse, discrimination and poverty fueled by transphobic stigma. Approaches to the HIV epidemic among TW and adolescents emphasize problem behaviors such as unprotected sex and substance. However, there has been a call for HIV research and interventions to understand and leverage community strengths. This qualitative study utilized a transgender-oriented, strength-based, intersectional and feminist approach to understand the strengths and protective health behaviors among 17 transgender adolescents and young women (TAYW) age 16–24 in Lima, Peru. Most participants re-located to Lima from the Amazon due to familial rejection, and engaged in obligatory sex work. TAYW demonstrated self-knowledge, motivation for education, efforts to secure employment, strong community networks, legal advocacy, avoiding problem substance use, HIV knowledge and condom use. However, strengths were impeded by multi-level barriers such as familial physical abuse, educational discrimination, and sexual assault which led to increased HIV vulnerability. We created a conceptual model of the “cycle” of HIV to describe the limits of personal responsibility within a vulnerable community denied access to family, education, employment and human rights. We recommend researchers, clinicians and public health workers follow the lead of TAYW at the frontlines of the HIV epidemic, and support beloved communities and enabling environments which may permit protective behaviors to mitigate HIV vulnerability.

Facilitators and barriers to implementing successful exclusion among children with shiga toxin-producing Escherichia coli: a qualitative analysis of public health case management records

BackgroundShiga toxin-producing Escherichia coli (STEC) infections are a significant public health concern as they can cause serious illness and outbreaks. In England, STEC incidence is highest among children and guidance recommends that children under six diagnosed with STEC are excluded from childcare until two consecutive stool cultures are negative. We aimed to describe the barriers and facilitators to implementing exclusion and the impact of exclusion policies on young children and their families.MethodsIndividual level data was obtained from a wider study focusing on shedding duration among STEC cases aged < 6 years between March 2018 – March 2022. Data was extracted from England’s public health case management system. The case management system includes notes on telephone conversations, email correspondence and meeting minutes relating to the case. Collected data consisted of free text in three forms: (1) quotes from parents, either direct or indirect, (2) direct quotes from the case record by health protection practitioners or environmental health officers, and (3) summaries by the data collector after reviewing the entire case record. We analysed free text comments linked to 136 cases using thematic analysis with a framework approach.ResultsThe median age of included cases was 3 years (IQR 1.5-5), with males accounting for 49%. Nine key themes were identified. Five themes focused on barriers to managing exclusion, including (i) financial losses, (ii) challenges with communication, engagement and collaboration, (iii) issues with sampling, processing, and results, (iv) adverse impact on children and their families and (v) conflicting exclusion advice. Four themes related to facilitators to exclusion, including (i) good communication with parents and childcare settings, (ii) support with childcare, (iii) improvements to sampling, testing, and reporting of results, and (iv) provision of supervised control measures.ConclusionsQualitative analysis of public health case records can provide evidence-based insights around complex health protection issues to inform public health guidelines. Our analysis highlights the importance of considering wider social and economic consequences of exclusion when developing policies and practices for the management of STEC in children.

Practical Aspects of the Simulation Course "Dispensary Observation at a Feldsher-Obstetric Station" as an Improvement in the Quality of Education

Currently, the protection of rural population health is of particular importance. This article presents the experience of organizing a simulation course "Dispensary observation at a Feldsher-Obstetric Station ", it also considers practical issues of its implementation and results.

Evaluating the Impact and Awareness of the Ayushman Bharat Scheme in Bihar

The Ayushman Bharat Scheme, India's largest health insurance initiative, was launched in 2018 with the goal of achieving Universal Health Coverage as outlined in the National Health Policy 2017. This scheme comprises two components: the National Health Mission, which focuses on strengthening health services and promoting awareness in rural and urban areas, and the National Health Protection Mission, which provides free treatment up to Rs. 5 lakhs for 50 crore individuals from economically disadvantaged families. A survey conducted in four districts of Bihar—Bhagalpur, Banka, Munger, and Khagaria—revealed that rural areas have a higher registration rate (58%) compared to urban areas (37%). Social media (31%) and newspapers (21%) are the primary sources of information about the scheme, while gender participation is relatively balanced, with 44% women and 56% men registered. Despite these positive indicators, issues such as paperwork, Aadhaar card problems, and lack of information hindered some from registering. The scheme received an average rating of 3.83 out of 5, reflecting general satisfaction and strong trust (97%) among respondents, though no respondents had yet used the card. To improve the scheme’s reach and effectiveness, it is recommended to increase awareness through targeted social media and newspaper campaigns, simplify the registration process, expand information dissemination, address technical issues, and encourage active usage of the Ayushman Bharat card.

Protocol for a randomized controlled trial of an internet-based prevention intervention for young children at-risk for functional abdominal pain

BackgroundChronic pain often clusters in families, where parents and their offspring both experience chronic pain conditions. Young children of parents with irritable bowel syndrome (IBS) represent an at-risk group for the development of abdominal pain, disability, and excess health care visits in later childhood. Parental solicitous responses to children’s expressions of discomfort and maternal modeling of their own illness behavior contribute to a greater focus on somatic sensations, leading to illness behaviors in children. This randomized controlled trial will test the effectiveness of an early preventive web-based psychosocial intervention (REACH)[TM] vs. an educational web-based safety comparison condition delivered to parents with IBS to alter parental responses and lead to improved child health and decreased health care costs.MethodsParents with IBS who have children ages 4–7 years are recruited via community-based approaches (e.g., social media advertisements, school electronic distribution, research networks) and health care providers. The target sample is 460 parents randomized to REACH, a web-based social learning and cognitive behavior therapy (SLCBT) intervention or an educational web-based safety comparison condition (EC). Participants will be assessed at baseline, 6-week (immediate post-intervention), 6-month, 12-month, and 18-month follow-up periods (months post-completion of intervention). The primary outcome is change in parental solicitous/protective behaviors. Secondary outcomes include parent risk and protective factors, child health and symptom outcomes, and health care utilization and cost savings.DiscussionThis study adapts a validated, parent-delivered intervention to treat chronic pain in children to a web-based application designed to prevent the development of chronic pain in very young, high-risk children. If successful, this strategy can both prevent adverse sequelae of this condition from developing as well as be widely accessible. Furthermore, the availability of a prevention model for parent training could result in significant short- and long-term health benefits across a broad spectrum of conditions.Trial registrationClinicalTrials.gov NCT05730491. Registered on February 15, 2023.

High-performance NO2 gas sensor based on reduced graphene oxide/ZrO2 hybrids

The increasing concern over environmental pollution, particularly from nitrogen dioxide (NO2) emissions, necessitates the development of efficient NO2 detection sensors. This study introduces reduced graphene oxide (rGO)/ZrO2 hybrids for enhanced NO2 gas sensing. Utilizing a modified Hummer’s method, graphene oxide (GO) flakes were synthesized and subsequently sputtered with 10 nm ZrO2 film, followed by thermal annealing to produce rGO/ZrO2 hybrids. The hybrids were characterized using various techniques including SEM, TEM, AFM, Raman spectroscopy, and XRD, confirming successful synthesis and reduction of GO, as well as the formation of ZrO2 nanoparticles. Gas sensing tests revealed superior sensitivity to NO2 in the hybrids due to efficient electron transfer between rGO and ZrO2, resulting in increased hole concentration in rGO and enhanced conductivity. The cyclic performance of the hybrids showed stable response and recovery to NO2, while selectivity tests demonstrated high sensitivity to NO2 over other gases including NH3, ethanol, and oxygen. This study highlights the potential of rGO/ZrO2 hybrids as high-performance NO2 gas sensors, offering promising prospects for environmental monitoring and public health protection.

Reliability and Safety Testing of a Ventilator Remote Control System Against Communication Failures and Network Disruptions.

The need for remote ventilator control has been highlighted by the COVID-19 Public Health Emergency. Remote ventilator control from outside a patient's room can improve response time to patient needs, protect health care workers, and reduce personal protective equipment (PPE) consumption. Extending remote control to distant locations can expand the capabilities of frontline health care workers by delivering specialized clinical expertise to the point of care, which is much needed in diverse health care settings, such as tele-critical care and military medicine. However, the safety and effectiveness of remote ventilator control can be affected by many risk factors, including communication failures and network disruptions. Consensus safety requirements and test methods are needed to assess the resilience and safety of remote ventilator control under communication failures and network disruptions. We designed two test methods to assess the robustness, usability, and safety of a remote ventilator control prototype system jointly developed by Nihon Kohden OrangeMed, Inc. and DocBox, Inc. ("the NK-DocBox system") to control the operation of an NKV-550 critical care ventilator under communication failures and network disruptions. First, the robustness of the NKV-550 ventilator was tested using a remote-control application developed on OpenICE - an open-source medical device interoperability platform - to transmit customized high-frequency and erroneous remote-control commands that could be caused by communication failures in a real-world environment. The second method utilized a network emulator to create different types and severity of network quality of service (QoS) degradation, including bandwidth throttling, network delay and jitter, packet drop and reordering, and bit errors, in the NKV-DocBox system to quantitatively assess the impact on system usability and safety. The NKV-550 ventilator operated as expected when remote-control commands arrived as fast as once per second. It ignored erroneous commands attempting to adjust invalid ventilation parameters. When facing commands that set the ventilation mode and parameters to invalid values, it reset the ventilation mode or parameters to default values, the safety implication of which may merit further evaluation. When any network QoS attribute (except for packet reordering) started to degrade, the NK-DocBox System experienced interference to its remote-control function, such as delays in the transmission of ventilator data and remote-control commands within the system. When the network QoS was worse than 500 ms network delay, 100 ms network jitter, 1% data drop rate, 12Mbps minimal bandwidth, or 1e-6 bit error rate, the system became unsafe to use. For example, ventilator waveforms visualized on the remote-control application demonstrated freezes, out-of-synchronization, and moving backwards; and the connection between the ventilator and the remote-control application became unstable. The presented test methods confirmed the robustness of the NKV-550 ventilator against high-frequency and erroneous remote control, quantified the impact of network disruptions on the usability, reliability, and safety of the NK-DocBox system and identified the minimum network QoS requirements for it to function safely. These generalizable test methods can be customized to evaluate other remote ventilator control technologies and remote control of other types of medical devices against communication failures and network disruptions.

Relationship between nursing students’ global climate change awareness, climate change anxiety and sustainability attitudes in nursing: a descriptive and cross-sectional study

BackgroundAs a major global health threat, climate change is an important issue for nurses who play a pivotal role in health protection and improvement, and in the development of climate-smart healthcare systems. Sustainability attitudes in nursing should be developed together with awareness and concern for climate change.AimThe aim of this study was to determine the relationship between nursing students’ global climate change awareness, climate change anxiety, and sustainability attitudes in nursing.MethodsThis descriptive, correlational study was conducted with 289 nursing students at a state university. Data were collected using the Descriptive Characteristics Form, the Global Climate Change Awareness Scale, the Climate Change Anxiety Scale, and the Sustainability Attitudes in Nursing Survey. Mean and percentage distributions, the Independent Samples t-test, ANOVA test, Pearson correlation and multiple regression analysis were used to analyze the data. The STROBE checklist was used to report this study.ResultsGlobal climate change awareness of the nursing students was at a moderate level, and the levels of climate change anxiety and sustainability attitudes in nursing were above average. There was determined to be a moderate positive correlation between climate change awareness and sustainability attitude in nursing, between anxiety and sustainability attitude in nursing, and between climate change awareness and anxiety. Climate change awareness and anxiety explained 25.1% of the sustainability attitude in nursing.ConclusionsThe study provides evidence of the relationship between nursing students’ global climate change awareness and anxiety, and sustainability attitudes in nursing. It can be recommended that climate change and sustainability awareness-raising content are integrated into the nursing curriculum. The development of a sustainability attitude in nursing will contribute to the development of sustainable and low-carbon healthcare practices.

Associations of mental health with vaccination readiness in informal caregivers and the vaccination status of their care recipients during the Covid-19 pandemic – A cross sectional analysis

IntroductionVaccinations are important for informal caregivers and their care recipients. Mental health problems are common among care givers. The aim of this study was to investigate vaccination readiness in informal caregivers and associations with mental health issues. Associations between vaccination readiness in informal caregivers and the vaccination status of their aged care recipients were examined. MethodsWithin the multicenter prospective registry study ‘Bavarian ambulatory Covid-19 Monitor (BaCoM) ‘, informal caregivers were asked for symptoms of depression (PHQ-9), burden of caretaking (BSFC-s), psychological antecedents of vaccination readiness (5C model) and previous Covid-19 infections of their care recipients. The vaccination status against Covid-19, seasonal influenza and pneumococcal disease was determined via vaccination certificates. Data analysis was performed using ordinal regressions and Mann-Whitney-U tests. ResultsData of n = 91 informal caregivers, associated with n = 84 care recipients were collected. Symptoms of depression were associated with reduced vaccination readiness (Calculation: p = 0.026, OR = 1.18), as well as the perceived burden of caretaking (Confidence: p = 0.006, OR = 0.88). A previous Covid-19 infection of the care recipients was associated with decreased vaccination readiness of informal caregivers (Median (Q1–Q3) Confidence: 5.0 (4.5–6.0) vs. 4.0 (3.0–5.0); Calculation: 5.0 (3.0–6.0) vs. 4.0 (1.0–5.0)). The vaccination status of the care recipients interrelated significantly with vaccination readiness of their informal caregivers (Confidence: p < 0.001; Complacency: p < 0.01; Constraints p < 0.05). No significant interrelations between vaccination readiness and the vaccination status against seasonal influenza or pneumococcal disease occurred. ConclusionMental health issues of informal caregivers seem to be associated with the actual vaccination status against Covid-19 in their care recipients. Target group specific counselling as well as an active involvement of informal caregivers in shared decision-making processes can be of relevance, but even more attention should be paid to the protection of mental health for informal caregivers.Trial registration number: German Register of Clinical Studies DRKS 26039.

Implicit attitudes toward obesity-related cues and their relation to body mass index, psychosocial functioning, and health behavior.

Differences in automatic cognitive processes exist among individuals with overweight and obesity, thus there is a need to expand our conceptualization of overweight and obesity to emphasize the predictive utility of these automatic processes, rather than focusing solely on behavioral outputs. Implicit association tests (IATs) may afford a noninvasive method of examining automatic preferences that might contribute to overweight and obesity; namely, preferences for unhealthy foods and sedentary behavior versus healthy foods and physical activity. The purpose of the current study was to examine whether implicit attitudes toward foods and physical activity differed based on body mass index (BMI) status. The relationships between implicit attitudes and key psychosocial factors and health behaviors were also examined. Participants (N = 127) included undergraduate students with an average age of 19.05 years old (SD = 1.52). Average BMI of the sample was 24.20 (SD = 4.93); 33.8% met criteria for overweight or obesity. Participants completed an IAT and questionnaires. There were no differences in implicit preferences based on BMI or BMI status. Overall, the sample demonstrated implicit preferences for healthy foods and active words, and preferences were not linked to the corresponding behavioral outputs, though preferences were linked to various indices of emotion and emotion regulation. Future research should explore an extended model to examine how implicit preferences might impact intentions to engage in protective versus risky obesity-related health behaviors, and the various psychosocial factors that might impact the translation of those preferences and intentions in actual behavioral outputs. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

Effects of Long-Term Application of Nitrogen Fertilizer on Soil Acidification and Biological Properties in China: A Meta-Analysis.

Soil acidification is a global environmental problem with significant impacts on agricultural production, environmental protection, and ecosystem health. Soil acidification is widespread in China, affecting crop yields, agricultural product quality, and biodiversity. Since the 1980s, much work has been done on acidic soils in China, but it is controversial whether excessive nitrogen fertilizer application can lead to soil acidification mechanisms. To address the above issues, we conducted a meta-analysis of 115 published papers to integrate and analyze the effects of N fertilizer application on soil acidification and biological properties from 1980 to 2024. We also quantified the effect of nitrogen fertilization on soil acidification and biological changes under different climatic conditions. The results showed that under long-term application of nitrogen fertilizers in China from 1980 to 2024, soil pH decreased by an average of 15.27%, and the activities of soil urease, nitrate reductase, nitrite reductase, catalase, glutamate dehydrogenase, and glutamate synthetase decreased by an average of 9.82-22.37%. The soil microbial community richness (Chao1 index) increased by 6.53%, but the community diversity (Shannon index) decreased by 15.42%. Among the dominant soil microorganisms, the relative abundance of bacteria decreased by an average of 9.67-29.38% and the abundance of gene expression of nifH, amoA-AOA, amoA-AOB, and qnorB decreased by 9.92-19.83%. In addition, we found that the mean annual temperature and rainfall impacted soil acidification via their effect on soil microbial diversity and community composition. This study provides a scientific basis for an in-depth understanding of the spatial and temporal variation of soil acidification and biological properties in China.

Monitoring and Ensuring Worker Health in Controlled Environments Using Economical Particle Sensors.

Nowadays, indoor air quality monitoring has become an issue of great importance, especially in industrial spaces and laboratories where materials are handled that may release particles into the air that are harmful to health. This study focuses on the monitoring of air quality and particle concentration using low-cost sensors (LCSs). To carry out this work, particulate matter (PM) monitoring sensors were used, in controlled conditions, specifically focusing on particle classifications with PM2.5 and PM10 diameters: the Nova SDS011, the Sensirion SEN54, the DFRobot SEN0460, and the Sensirion SPS30, for which an adapted environmental chamber was built, and gaged using the Temtop M2000 2nd as a reference sensor (SRef). The main objective was to preliminarily assess the performance of the sensors, to select the most suitable ones for future research and their possible use in different work environments. The monitoring of PM2.5 and PM10 particles is essential to ensure the health of workers and avoid possible illnesses. This study is based on the comparison of the selected LCS with the SRef and the results of the comparison based on statistics. The results showed variations in the precision and accuracy of the LCS as opposed to the SRef. Additionally, it was found that the Sensirion SEN54 was the most suitable and valuable tool to be used to maintain a safe working environment and would contribute significantly to the protection of the workers' health.