Child Health Research Articles

Transmission Channel of Agriculture Food Import Tariff to Stunting Prevalence

Increases in food prices affect poverty in a way that poor consumer is harmed due to the high proportion of their budget they spent on food. Stunting prevalence might be instigated by several factors such as access to food and nutrition intake, genetic and environment. This research aims to analyse the effect of food import tariffs towards the stunting prevalence of children aged under 5 (five) across districts in Indonesia, and we explore the indirect relationship between stunting prevalence and trade policy. This research uses quantitative descriptive research methods, utilizing both primary and secondary data. Primary data were obtained through the distribution of questionnaires, followed by Focus Group. Secondary data were obtained from relevant institutions such as the Central Statistics Agency, research journals, and related books. The method of data analysis in the study uses quantitative analysis with a mathematical model. The results showed that tariffs can reduce the consumption of foods that serve in the intake of dietary nutrients such as calories, protein and fat. As a result, food intake affects the prevalence of stunting. Trade liberalisation can have a beneficial impact on child health. The effects of trade liberalisation on stunting through the food channel include: a) trade has a significant effect on calorie, protein, and fat intake, b) intake of these nutrients has a significant effect on child stunting.

Implications of the Cass Review for health policy governing gender medicine for Australian minors.

To summarize the key recommendations of England's independent inquiry into gender identity services for children and young people (the Cass Review) and to evaluate their relevance to Australian health policy. The Cass Review's findings and recommendations have clear applicability to Australian health policy. As a matter of priority, Australian health authorities need to seriously engage with the Cass Review's findings and recommendations. To not do so will put the health and well-being of vulnerable children and young people at risk.

Associations among screen time, sleep, mental health and cognitive functioning in school-aged children during the COVID-19 pandemic, November 2020 through to August 2022

ObjectiveTo examine children’s screen time use and sleep patterns over 2 years of the pandemic and the downstream associations with children’s executive functions and behavioural problems, as well as the moderating effects of parental factors. MethodThis longitudinal cohort study examined school-aged children’s lifestyle and behavioural changes over 2 years of the pandemic across 6 timepoints (November 2020 to August 2022). Latent growth modeling (LGM) was used to identify changes in screen time and sleep duration and multivariate LGM was used to determine how parental stress, positive parenting, changes in children’s screen time and sleep over time were associated with children’s executive functions and mental health outcomes at the final time point. ResultsA total of 198 parents (children’s mean age = 9.14 years) were recruited and followed up. Non-school screen time was high at the initial timepoint (3.6±2.3 hours). Positive parenting at the initial timepoint was associated with lower screen time use in children (β=-.19, p<0.001; β=-.19, p<.001, in internalizing and externalizing models). Children whose screen time use was constant during the pandemic had shorter sleep durations (β=-.45, p<0.05 in internalizing model). Executive function was predicted by sleep duration at the first timepoint (β=-.55, p<.001; β=.73, p<.001, in internalizing and externalizing models) and changes in screen time during the pandemic was associated with both internalizing and externalizing symptoms (β=.58, p<.05; β=.54, p<.05, in internalizing and externalizing models). ConclusionChildren’s screen time decreased slightly but remained significantly higher than Canadian and International guidelines during 2 years of the pandemic. Positive parenting styles can have a significant impact on children's screen time use. Reducing excessive screen time can help improve sleep patterns and, consequently, cognitive, and emotional well-being in children.

Correlation of Parenting Styles and Oral Health Behavior of Children with Down Syndrome in Banjarmasin

Background: Parental, Down syndrome is a trisomy chromosomal genetic disorder that leads newborn child having more than one chromosome so that could interfere the normal growth of the body due to an excess of protein level. Children with Down syndrome have different oral health problems compared to the general population. They need assistance to maintain their oral health because of mental and physical deficiencies as well as limitations in optimally cleaning their teeth. Objective: To analyze the relationship between parenting styles and oral health behavior of children with Down syndrome in Banjarmasin Special Needs School, Indonesia. Materials and Method: This is an observational analytic study with cross-sectional approach. Sample was taken using simple random sampling technique and a cross-sectional sample formula obtained for 32 respondents. The instrument used a parenting style questionnaire and a behavioral modification questionnaire for children's oral health. Results: Democratic (87.5%) compared switch order parenting styles. It was found that there were more children with Down syndrome in the category of moderate behavior (59%) than children with good behavior (38%) and poor behavior (3%). The results of the Somers'd test data analysis obtained a significance value of 0.034 (p&lt;0.05) and the correlation value obtained was 0.571, which means that the correlation strength is moderate with a positive correlation direction (unidirectional). Conclusion: The more democratic the parents use as parenting style the better the oral health behavior of children with Down syndrome will be.

Investigating associations between climate change anxiety and mental health impact on vulnerable populations: A qualitative analysis.

Climate anxiety has a negative impact on the mental health and psychological wellbeing of the vulnerable population. The goal is to assess many factors that affect mental health and psychological wellbeing, as well as how climate change affects mental health in Pakistan's vulnerable population. This study provides evidence-based insights on the long- and medium-term impacts of extreme weather events on mental health. We conducted semi-structured interviews with a sample of 72 students aged 10-16 years, employing an exploratory qualitative design. The resulting process identified themes and questions for future research on climate change and its psychological effects on children's mental health. As a result, positive emotions embedded in children's climate strategic actions in parent and community contexts helped to mitigate children's perceptions of negative emotions (such as climate anxiety, phobias, fear, sleep disorders, depression, sadness, and substance abuse). Climate change's effects can have a significant impact on mental health. We will be discussing effective strategies to address the expected mental health issues among children caused by climate change. The discussion paper offers a set of recommendations for addressing the mental health impacts of climate change, including improving mental health support systems, integrating climate change education into services, and developing targeted interventions for vulnerable populations.

Outcome of Vaginal Hysterectomy versus Abdominal Hysterectomy for Benign Non-Prolapsed Uterus

Introduction: Hysterectomy is a very frequent pregnancy-unrelated surgical procedure performed in women, which may be accomplished either by abdominal or vaginal route. This study aims to assess the advantages of vaginal hysterectomy compared to abdominal hysterectomy in women with benign gynecological disorders other than prolapse. Aim of the study: The aim of this study was to compare the outcomes of vaginal hysterectomy and abdominal hysterectomy in treating benign non-prolapsed uterus. Methods: This cross-sectional comparative study was conducted among 60 patients at the Department of Obstetrics and Gynaecology, Institute of Child and Mother Health (ICMH), Dhaka, from May 2015 to October 2015. The study included 30 patients who underwent vaginal hysterectomy and 30 patients who underwent abdominal hysterectomy. Data collection involved recording patient history, conducting clinical examinations, and documenting information in a pre-designed data collection sheet. Data were analyzed using SPSS version 22.0. Result: This study included a total of 60 patients, with 30 undergoing abdominal hysterectomy (AH) and 30 undergoing vaginal hysterectomy (VH). Baseline characteristics were similar between the two groups. There were no intraoperative complications in either group. The operation time, intraoperative blood loss, time to out-of-bed activity, mean maximum postoperative body temperature, and duration of fever were all significantly shorter and less severe in the VH group compared with the AH group. Additionally, vaginal length in the VH group was significantly shorter than in the AH group. Conclusion: Vaginal hysterectomy offers advantages over abdominal hysterectomy in treating benign gynecological diseases, providing greater efficacy and safety with less invasiveness.

Effect of Indoor Air Quality on Respiratory Health of Children: An MPPD Model Approach

Effect of Indoor Air Quality on Respiratory Health of Children: An MPPD Model Approach

An Overview of Common Infectious Diseases in Children Under Five

Infectious diseases remain a significant concern for children under five, often leading to substantial morbidity and, in some cases, mortality. This review provides an overview of prevalent infectious diseases affecting this vulnerable age group, including Measles, Chickenpox, Common cold, Pertussis, Conjunctivitis, Eczema, Gastroenteritis, Influenza, Sore throat, Fever in children, Malaria, Meningococcal disease, and Urinary tract infection. Each condition is discussed in terms of its etiology, clinical presentation, diagnosis, treatment, and preventive strategies. Understanding the unique aspects of these diseases in young children is critical for effective management and prevention. Vaccination, improved hygiene practices, and early medical intervention play pivotal roles in reducing the incidence and impact of these infections. This comprehensive review aims to equip healthcare providers, caregivers, and policymakers with the knowledge needed to protect and promote the health of children under five. Key words Chickenpox, Common cold, Conjunctivitis, Eczema, Gastroenteritis, Infectious diseases, Influenza, Malaria, Measles, Meningococcal disease, Pertussis, Sore throat, Urinary tract infection.

The implementation of the guideline for the management of pediatric off-label use of drugs in China: a cross-sectional study.

Previously, we developed the Guidelines for the Management of Pediatric Off-Label Use of Drugs in China in addressing the need for standardization of pediatric off-label drug use. As the implementation of recommendations in Guidelines among healthcare professionals is weak, it is important to identify barriers to guideline implementation for developing appropriate strategies for specific settings and target groups. This study aimed to assess the difficulty and urgency in implementing the recommendations in the Guideline, identifying the factors affecting the implementation of these recommendations to realize the clinical translation of the Guideline. A cross-sectional study was conducted from March 1 to June 17, 2022. Pediatricians, pharmacists, and health managers from all 31 mainland Chinese provinces were involved. The electronic questionnaires were distributed nationwide by The Clinical Pharmacology Group of the Pediatric Society of the Chinese Medical Association and the National Clinical Research Center for Child Health. Data analysis, including frequency, percentages, averages, and standard deviations was performed using Microsoft Excel 16.54. Chi-squared tests, multi-factor logistic regression, and linear regression were analyzed in SPSS 23.0. A Sankey diagram was constructed using R software. A total of 869 valid questionnaires were collected from 491 participating organizations. More than half of the recommendations were implemented, and 12 recommendations were implemented more in tertiary hospitals than in secondary hospitals. The mean urgency scores of all 21 recommendations were over 5. The mean difficulty scores of all 21 recommendations were over 4. The percentage of the most urgent was 44.33%, and the least urgent was 1.45%. The most difficult portion was 12.03%, and the least difficult was 5.74%. Factors impacting the urgency and difficulty of guideline implementation were different, with common influences including the position, education level of clinicians and hospital level. The recommendations in the Guideline for the Management of Pediatric Off-Label Use of Drugs are considered highly urgent for implementation in China. Nevertheless, the study revealed challenges in applying all 21 recommendations within clinical practice. The key factors affecting implementation include the position, education, experience, and hospital level of healthcare professionals. It is recommended to facilitate implementing the recommendations by sharing experience across various hospital levels, starting from high-level hospitals and extending to primary healthcare settings. Moreover, adjustments to the professional structure within hospitals are needed to enhance the management of off-label drug use in pediatric patients.

Midwifery assessment and interventions protocol for adolescent pregnancy: a Delphi method approach

Background: Adolescence pregnancy poses risks for both mothers and infants, often due to insufficient prenatal care resulting from societal stigmatization and lack of awareness. Around 16 million adolescents aged 15-19 years in the world give birth each year; in Indonesia, the first pregnant women aged &lt;20 years are 45.10%, while in West Sumatra, it is 33.7%. To address this issue, integrated programs and midwifery care have been implemented. However, providing such care to adolescent mothers comes with its own set of challenges.Purpose: This study aims to conduct a midwifery assessment and intervention protocol for adolescent pregnancy.Method: Qualitative approach The Delphi method involved two rounds of evaluation, with twenty-one participants who were independent practice midwives, six midwives involved in the mother and child health program, and nine midwifery lecturers from accredited educational institutions A (excellent). Participants had at least five years of clinical experience and were selected using purposive non-probability sampling. Participants evaluated statements related to midwifery care during the Delphi process. The validity of these statements was determined by participants providing a minimum score of 3, and the Content Validity Ratio (CVR) was calculated. Statements with a CVR greater than 0.8 were considered valid.Results: Based on expert consensus, important assessments for adolescent pregnant women include addressing issues of gender equality and domestic violence, reproductive and sexual health, risks associated with smoking and substance abuse, maintaining a healthy pregnancy, and adequately preparing for labor and parenthood.Conclusion: Midwifery management and midwifery information were deemed valid dimensions of midwifery care; relational care had one invalid item.

Peculiarities of arterial hypertension in pregnancy from the point of view of evidence-based medicine

Background: Arterial hypertension during pregnancy is a significant public health issue, affecting 10-15% of pregnancies globally. It encompasses gestational hypertension, preeclampsia, and chronic hypertension, which are leading causes of maternal and fetal morbidity and mortality. Understanding and managing these hypertensive disorders is crucial due to their impact on maternal and child health outcomes. Recent advancements in screening, diagnostic criteria, and treatment options have significantly improved clinical practices, emphasizing the importance of evidence-based management. Methods and Materials: This study adopts an evidence-based methodology, combining qualitative and quantitative research to investigate arterial hypertension in pregnancy. A systematic literature review was conducted using databases such as PubMed, Cochrane Library, and ScienceDirect. Comparative and statistical analyses were performed to evaluate diagnostic and treatment efficiencies across various studies. The study aims to synthesize current data on epidemiology, risk factors, and management outcomes to enhance clinical guidelines and improve maternal-fetal health. Results: The findings highlight the significant global burden of hypertensive disorders in pregnancy, with varying prevalence across different regions influenced by genetic, healthcare access, and socioeconomic factors. Effective management strategies include both pharmacological interventions, such as the use of labetalol, methyldopa, and nifedipine, and non-pharmacological approaches, including dietary modifications and lifestyle changes. The study also underscores the importance of early detection and personalized treatment plans to mitigate adverse outcomes. Conclusion: The study concludes that hypertensive disorders in pregnancy pose substantial risks to maternal and fetal health, necessitating precise diagnostic protocols and evidence-based therapeutic interventions. Public health strategies, including educational programs and community-based interventions, are essential in raising awareness and preventing these conditions. Continued research and clinical practice improvements are vital to better understanding and managing hypertension in pregnancy, ultimately improving health outcomes for mothers and future generations.

Health-related quality of life in 153 children with neuromuscular disorders in Latin America: is it age, functional dependence or diagnosis?

Neuromuscular diseases impact on children's health related quality of life but there is a lack of studies in Latin America that measured this construct. To respond to this need, this study aimed to explore quality of life and its relationship with age, functional dependence and specific diagnosis in children and adolescents in Latin America. A cross-sectional correlation study was carried out with 133 caregivers on children (2–18 years old) with various neuromuscular disorders. Parents reported on their children's health related quality of life through the PedsQL GCS and the PedsQL NMM. Differences in quality of life were found when comparing children with high functional dependence with those with mild dependence (p = 0.05). No significant differences were found regarding the child diagnosis. Finally, quality of life was highly correlated with the child's age, even when controlling for functional dependence differences between ages. Children and adolescents with neuromuscular show a diminished health related quality of life, not only in physical functioning but in their psychosocial functioning. Health related quality of life may vary according to the child's age and functional dependence.

Assessing brain iron and its relationship to cognition and comorbidity in children with ADHD with quantitative susceptibility mapping (QSM)

BackgroundQuantitative susceptibility mapping (QSM) is a neuroimaging technique that detects local changes in magnetic susceptibility induced by brain iron. Brain iron and the dopaminergic system are linked since iron is an important cofactor for dopamine synthesis. ADHD is associated with dysregulation of dopaminergic transmission. Therefore, we applied QSM on subcortical structures, to study potential alterations in brain iron and its impact on cognition and mental health in children with ADHD. Methods3 Tesla QSM-data of 111 participants (nADHD= 58, mean age: 13.2 (0.63); nControls=53, mean age: 13.2 (0.51)) were analyzed. Subcortical regional brain iron values were extracted. ANOVAs examined group differences for each region of interest. For dimensional approaches, Pearson correlation analysis was performed across the cohort examining the association with symptoms, mental health, and cognition. ResultsNo significant differences were found in iron susceptibility between ADHD and control, between persistent and remitted ADHD, or between medication use. An unexpected finding was that children with internalising disorder had significantly higher iron susceptibility, but the result did not survive multiple comparison corrections. Higher brain iron was associated with sustained attention, but not on inhibition, IQ, and working memory. ConclusionThis is the first study addressing brain iron susceptibility and its association with comorbidities and cognition in ADHD. Alterations in brain iron may not account for the full diagnosis of ADHD but may be an indicator of internalising problems in children. Alterations in brain iron content in children were linked to detrimental sustained attention and may represent developmental variation in cognition.

‘Release them into the wild, but how far can they go?’ Improving social and emotional mental health through teaching bushcraft skills to children with special educational needs and disability: a preliminary case series evaluation study

ABSTRACT Previous research indicates that outdoor activity and learning programmes are a beneficial educational approach, but studies have neglected to consider how well this approach may address the social, emotional and mental health needs of children with Special Educational Needs and Disability (SEND). In this study, seven Key-Stage 3 children with SEND (aged 11 to 14) from a special educational needs provision within a mainstream school attended a five-week ‘bushcraft’ programme. Standardised psychometric measures of self-concept were completed by children before and after the intervention, and teachers rated pupils’ stress levels before and after. Results indicate that the programme was associated with a range of mental health, social and emotional benefits, suggesting that teaching bushcraft skills to this group is an acceptable, feasible and effective intervention leading to improvements in social and emotional function and mental health in children with SEND. Directions for future programme development and evaluation are considered.

Network pharmacology, molecular docking, and molecular dynamics simulations shed light on the mechanism behind Gynostemma pentaphyllum's efficacy against osteosarcoma.

Osteosarcoma (OS) is the most common type of malignant bone tumor, that poses a serious threat to the lives and health of children and adolescents. Traditional Chinese medicines (TCM) have gained attention for treating OS because of their potent anti-cancer effects and fewer side effects. It is commonly understood that Gynostemma pentaphyllum (Thunb.) Makino (GP) exhibits inhibitory effects on most tumors. However, the knowledge of the systematic mechanisms involved is limited. In this study, the Traditional Chinese Medicine Systems Pharmacology Database and Analysis Platform (TCMSP) was searched to screen the effective ingredients and corresponding target genes of GP, and disease target databases were searched to identify relevant targets for OS. Venn analysis was used to visualize overlapping genes, which were further extracted using the protein-protein interaction network. R software was used to conduct gene ontology and Kyoto encyclopedia of genes and genomes pathway enrichment analysis, molecular docking and molecular dynamics simulation further validate the binding efficacy of potential therapeutic targets to compound molecules. In total, 161 and 1981 proteins were identified as target genes of GP and OS, respectively, and 104 overlapping genes were identified. Through analysis of the core subnetwork, 12 hub genes were identified, and Kyoto Encyclopedia of Genes and Genomes pathway enrichment analyses revealed that the PI3K/Akt signaling pathway was the most significant. Molecular docking and molecular dynamics simulations show that a high affinity between quercetin and these targets, especially with the combination of TNF free energy (Δ Gbind) minimum, MM/PBSA and MM/GBSA is 42.85 kcal/mol, respectively, and 45.29 kcal/mol. The active ingredients Rhamnazin and Quercetin in Gypenoylum play a therapeutic role in OS through several key targets and pathways. This study provides ideas and references for further research on drug development.

Changes in School-Age Children's Well-being and School-Related Needs Post COVID-19 Pandemic.

COVID-19 highlighted the importance of schools for child health, as emerging data suggest that pandemic-related school closures may have led to worsening child health and exacerbated health disparities. This study examines school-aged children's well-being, and characterizes changes in school-related needs, from 2021 to 2022. This is a secondary analysis of a longitudinal cohort study, where a nationally representative sample of parents of school-aged children were surveyed in June 2021 and 2022. The percentage of children with deficits in total difficulties, hyperactivity, and prosocial behavior decreased at follow-up, while a high percentage of children continued to experience peer problems. At least one school-related need remained for most parents. Highest priority needs were academic enrichment, socialization, physical activity, tutoring, and coping with stress. Academic support and social-emotional well-being remained major parental concerns, with social development showing significant deficit. Improvements in child well-being were experienced unequally across demographic groups.

Determinants of Risk Factors Associated with Low Birth Weight in Nigeria

Low birth weight (LBW) remains a significant public health challenge with profound implications for neonatal and child health, particularly in low-income countries. Defined by the World Health Organization as a birth weight of less than 2.5 kilograms, LBW contributes to increased neonatal mortality and long-term developmental issues. This study examines the prevalence and determinants of LBW in Nigeria, leveraging data from the 2018 Nigeria Demographic and Health Survey (NDHS). The study employs a cross-sectional design and a stratified two-stage sampling technique, analyzing 7,728 recorded birth weights. Key findings indicate that maternal age, education, and socio-economic status significantly influence birth weight. Optimal reproductive ages (25-34 years) and higher educational attainment are associated with healthier birth weights, whereas younger (below 20 years) and older mothers (above 40 years), and those with lower education levels, face higher LBW risks. Employment and wealth are positively correlated with better birth outcomes, underscoring the importance of financial stability. Environmental factors such as urban residence, access to improved water sources, and sanitation facilities also play crucial roles in determining birth weight. The study compares frequentist logistic regression and Bayesian structured additive logistic regression models to identify and predict LBW risk factors, highlighting regional disparities within Nigeria. The findings emphasize the need for targeted interventions addressing socio-demographic, socio-economic, and environmental determinants to reduce the prevalence of LBW and improve maternal and child health outcomes. Enhanced understanding of these factors through advanced statistical modeling can inform policy and health interventions, ultimately contributing to achieving global health targets and improving neonatal health in Nigeria.

Impact of integrated WASH and maternal and child health interventions on diarrhea disease prevalence in a resource-constrained setting in Kenya

BackgroundWater, sanitation and hygiene (WASH) and child health interventions are proven simple and cost-effective strategies for preventing diarrhea and minimizing excess mortality. Individually, they are able to prevent diarrhea though sub-optimally, and their effectiveness when combined may be higher. This study examined the effect of integrated WASH and maternal and child health (MCH) interventions on prevalence of diarrhea, in a resource-limited setting in Kenya.MethodsA controlled intervention was implemented in Narok County. The interventions included WASH interventions integrated with promotion of MCH. A structured questionnaire was used to collect data on targeted indicators before and after the interventions. Data were analyzed using descriptive statistics and Chi-square to establish the impact of the interventions.ResultsA total of 431and 424 households and 491 and 487 households in intervention and control sites, respectively, participated in the baseline and endline surveys. Following implementation of the interventions, prevalence of diarrhea decreased by 69.1% (95% CI: 49.6–87.1%) and 58.6% (95% CI: 26.6–82.4%) in the intervention and control site, respectively. Treatment of drinking water and animal husbandry practices were significantly associated with diarrhea post-interventions.ConclusionsIntegrating WASH interventions with other diarrhea control strategies and contextualizing them to meet site-specific needs may effectively prevent diarrhea.

Early neonatal mortality and determinants in Ethiopia: multilevel analysis of Ethiopian demographic and health survey, 2019

IntroductionDespite remarkable achievements in improving maternal and child health, early neonatal deaths still persist, with a sluggish decline in Ethiopia. As a pressing public health issue, it requires frequent and current studies to make appropriate interventions. Therefore, by using the most recent Ethiopian Mini Demographic Health Survey Data of 2019, we aimed to assess the magnitude and factors associated with early neonatal mortality in Ethiopia.MethodsSecondary data analysis was conducted based on the demographic and health survey data conducted in Ethiopia in 2019. A total weighted sample of 5,753 live births was included for this study. A multilevel logistic regression model was used to identify the determinants of early neonatal mortality. The adjusted odds ratio at 95% Cl was computed to assess the strength and significance of the association between explanatory and outcome variables. Factors with a p-value of < 0.05 are declared statistically significant.ResultsThe prevalence of early neonatal mortality in Ethiopia was 26.5 (95% Cl; 22.5–31.08) per 1000 live births. Maternal age 20–35 (AOR, 0.38; 95% Cl, 0.38–0.69), richer wealth index (AOR, 0.47; 95% Cl, 0.23–0.96), having no antenatal care visit (AOR, 1.86; 95% Cl, 1.05–3.30), first birth order (AOR, 3.41; 95% Cl, 1.54–7.56), multiple pregnancy (AOR, 18.5; 95% Cl 8.8–38.9), presence of less than two number of under-five children (AOR, 5.83; 95% Cl, 1.71–19.79) and Somali region (AOR, 3.49; 95% Cl, 1.70-12.52) were significantly associated with early neonatal mortality.ConclusionThis study showed that, in comparison to other developing nations, the nation had a higher rate of early newborn mortality. Thus, programmers and policymakers should adjust their designs and policies in accordance with the needs of newborns and children’s health. The Somali region, extreme maternal age, and ANC utilization among expectant moms should all be given special consideration.

Social determinants of health and somatic growth in preterm infants and children with chronic lung disease.

Bronchopulmonary dysplasia (BPD), a common complication of prematurity, is associated with impaired lung function and increased morbidity in childhood. These children display heterogeneous somatic growth patterns which may ultimately impact their risk for later respiratory disease. We aim to understand the relationship between socioenvironmental exposures and growth in this population. A retrospective longitudinal cohort study was conducted using participants (n = 616) enrolled in the Johns Hopkins Outpatient BPD Registry. Growth measurements between 0 and 36 months of age were obtained. Somatic growth measurements, both corrected and uncorrected for gestational age, were converted to z-scores using Center for Disease Control and Prevention normative data. Using a participant's residential zip code, we utilized the 2019 Area Deprivation Index (ADI), the Childhood Opportunity Index (COI) 2.0, and neighborhood food insecurity data from the Maryland Food Bank. Linear regression analysis was performed employing individual socioenvironmental measures as independent variables and growth z-scores as dependent variables in univariate analysis. Univariate analysis was repeated adjusting for gestational age, BPD severity, and the presence of a gastrostomy tube (GT). Of the three measures analyzed, national COI (nCOI) showed a significant association with mean weight z-scores, mean ADI showed some association with mean weight z-scores, and the percentage of a community experiencing food insecurity showed no association with mean weight z-scores. After adjusting for gestational age, BPD severity, and presence of a GT, children living in areas of greater opportunity (higher nCOI values), had significantly lower weight z-scores at 12 months corrected and at 24 and 36 months uncorrected CONCLUSIONS: Our findings suggest that the COI 2.0, a multidimensional measure, captures more facets of an individual's social environment, as compared to the singular nature of a measure of food insecurity. There are several potential explanations for the phenomenon seen, and further understanding of this dynamic is crucial for designing effective interventions and policies to better address inequities in outcomes.