Many ethnic minority autonomous regions in China, mainly in mountainous areas, have caused great harm to people’s life and property safety due to frequent geological disasters. Therefore, it has become an urgent task for the government to create a system for predicting, preventing and effectively responding to disasters, and to strengthen the ability of relevant regions to jointly resist disasters. This paper takes Mabian Yi Autonomous County as the research object, and studies the disaster management of Mabian Yi Autonomous County. The research focuses on geological disaster vulnerability evaluation, geological disaster hazard evaluation, geological disaster risk evaluation, and geological disaster carrying capacity evaluation. The two elements of geological disaster risk evaluation are vulnerability evaluation and hazard evaluation. The main element of geological disaster carrying capacity evaluation is risk evaluation. Through evaluation, it is found that the central and eastern regions of Mabian Yi Autonomous County can be used as population concentration areas and develop modern agriculture and tourism. The western and northeastern regions can be used as nature reserves. Based on the above evaluation results, the disaster management opinions of Mabian Yi Autonomous County are given. This makes the government have a certain reference basis in the preparation of regional construction policy planning. From the perspective of unique disaster management, this paper provides the government with a political governance model for ethnic minority areas through the harmonious development of man and nature, to achieve a goal of sustainable development.