Event Abstract Back to Event A MEG investigation of cortical and subcortical networks involved in human voluntary saccades and smooth pursuit eye movements Andreas A. Ioannides1*, Peter B. Fenwick1 and Lichan Liu1 1 AAI Scientific Cultural Services Ltd., Lab. for Human Brain Dynamics, Cyprus There is no consensus yet about either the precise location of the human eye fields or the way the underlying neural network is recruited for saccades and smooth pursuit eye movements. We designed a protocol to separate activity related to decision, planning and the command to execute the eye movements. We used this protocol to record the MEG signal while subjects performed saccadic and smooth pursue eye movements. Magnetic Field Tomography (MFT) allowed us to identify the positions of frontal and parietal eye fields and eye movement related activity in the cerebellum and brainstem during planning and just before the execution of voluntary saccades and smooth tracking. Activity in these areas (both in the time and frequency domains) was compared between saccades, smooth tracking and during blinking. The time domain analysis showed a very complex pattern of activity, with distinct features when the solutions were aligned to the cues and the eye movement onset. The analysis in the frequency domain showed significant changes in activity over a very wide spectrum of frequencies extending to the highest frequencies (~600 Hz) allowed by the hardware filters. The blink analysis, confirmed the prediction of strong eye field activation just anterior to the central sulcus, and showed also activity in the more anterior FEFs bilaterally, and in parietal areas. A striking feature of our results was the rather asymmetric activity associated with saccades to the left and right. We identified the expected preponderance of contralateral cortical and ipsilateral brainstem and cerebellum activities. In addition we observed more left frontal cortex activity (including left FEF) associated with the (presumably conscious) control of saccade execution and a more right frontal cortex activity (including right FEF) for the early (possibly unconscious) planning of saccades. Some of these results were best over a very wide frequency range and hence in the data obtained with fast sampling. Conference: Biomag 2010 - 17th International Conference on Biomagnetism , Dubrovnik, Croatia, 28 Mar - 1 Apr, 2010. Presentation Type: Poster Presentation Topic: Sensory Processing and Functional Connectivity Citation: Ioannides AA, Fenwick PB and Liu L (2010). A MEG investigation of cortical and subcortical networks involved in human voluntary saccades and smooth pursuit eye movements. Front. Neurosci. Conference Abstract: Biomag 2010 - 17th International Conference on Biomagnetism . doi: 10.3389/conf.fnins.2010.06.00160 Copyright: The abstracts in this collection have not been subject to any Frontiers peer review or checks, and are not endorsed by Frontiers. They are made available through the Frontiers publishing platform as a service to conference organizers and presenters. The copyright in the individual abstracts is owned by the author of each abstract or his/her employer unless otherwise stated. Each abstract, as well as the collection of abstracts, are published under a Creative Commons CC-BY 4.0 (attribution) licence (https://creativecommons.org/licenses/by/4.0/) and may thus be reproduced, translated, adapted and be the subject of derivative works provided the authors and Frontiers are attributed. For Frontiers’ terms and conditions please see https://www.frontiersin.org/legal/terms-and-conditions. Received: 26 Mar 2010; Published Online: 26 Mar 2010. * Correspondence: Andreas A Ioannides, AAI Scientific Cultural Services Ltd., Lab. for Human Brain Dynamics, Nicosia, Cyprus, a.ioannides@humanbraindynamics.com Login Required This action requires you to be registered with Frontiers and logged in. To register or login click here. Abstract Info Abstract The Authors in Frontiers Andreas A Ioannides Peter B Fenwick Lichan Liu Google Andreas A Ioannides Peter B Fenwick Lichan Liu Google Scholar Andreas A Ioannides Peter B Fenwick Lichan Liu PubMed Andreas A Ioannides Peter B Fenwick Lichan Liu Related Article in Frontiers Google Scholar PubMed Abstract Close Back to top Javascript is disabled. Please enable Javascript in your browser settings in order to see all the content on this page.
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