Preliminary results of optimization of the method of haploproducer Zea mays L. for hybrid genotypes of spring common wheat Triticum aestivum L. in order to create diploidized haploid lines and their integration into practical breeding are presented. Regularities of the regeneration of normal chlorophyll-bearing haploid plants and the dependence of the morphogenesis of haplo-embryoids in vitro on optimization factors of various genesis and their effectiveness on hybrids created on the basis of varieties of different ecological and geographical origin were revealed. It was found that the manifestation of the effect of heterosis contributes to an increase in the yield of haploid chlorophyll-bearing regenerants when receiving hybrids from parental forms with different responsiveness to androgenesis and haploproducing. The advantage of the ecological-geographical principle of selection of parental pairs in increasing the degree of responsiveness of hybrid genotypes of spring wheat to in vitro androgenesis and haploproducing is shown. The practical advantage of the haploproducer method in the F1 system of T. aestivum - Z. mays in comparison with the androgenesis method in the anther culture in vitro is a higher optimization potential in summa. In order to intensify the biotechnological breeding process, it is recommended to use the optimized method of the haploproducer - Z. mays, which provides for the cumulative twel-method of pollination with a mixture of pollen from maize lines with different haplo-producing properties (increasing the quantitative yield of haplo-embryos) and a hormone stimulation scheme with pretreatment of the spike material of the hybrids with epibrassinolide (increasing the degree of their differentiation), which in total makes it possible to significantly accelerate the creation of diploidized haploid lines, regardless of the influence of the genotype of the original hybrids.