To date, 14 high-redshift ($z>1.0$) galaxy clusters with mass measurements have been observed, spectroscopically confirmed, and are reported in the literature. These objects should be exceedingly rare in the standard $\ensuremath{\Lambda}$ cold dark matter ($\ensuremath{\Lambda}\mathrm{CDM}$) model. We conservatively approximate the selection functions of these clusters' parent surveys and quantify the tension between the abundances of massive clusters as predicted by the standard $\ensuremath{\Lambda}\mathrm{CDM}$ model and the observed ones. We alleviate the tension, considering non-Gaussian primordial perturbations of the local type, characterized by the parameter ${f}_{\mathrm{NL}}$, and derive constraints on ${f}_{\mathrm{NL}}$ arising from the mere existence of these clusters. At the $95%$ confidence level, ${f}_{\mathrm{NL}}>467$, with cosmological parameters fixed to their most likely WMAP5 values, or ${f}_{\mathrm{NL}}\ensuremath{\gtrsim}123$ (at $95%$ confidence) if we marginalize over prior WMAP5 parameters. In combination with ${f}_{\mathrm{NL}}$ constraints from cosmic microwave background and halo bias, this determination implies a scale dependence of ${f}_{\mathrm{NL}}$ at $\ensuremath{\simeq}3\ensuremath{\sigma}$. Given the assumptions made in the analysis, we expect any future improvements to the modeling of the non-Gaussian mass function, survey volumes, or selection functions to increase the significance of ${f}_{\mathrm{NL}}>0$ found here. In order to reconcile these massive, high-$z$ clusters with ${f}_{\mathrm{NL}}=0$, their masses would need to be systematically lowered by $1.5\ensuremath{\sigma}$, or the ${\ensuremath{\sigma}}_{8}$ parameter should be $\ensuremath{\sim}3\ensuremath{\sigma}$ higher than cosmic microwave background (and large-scale structure) constraints. The existence of these objects is a puzzle: it either represents a challenge to the $\ensuremath{\Lambda}\mathrm{CDM}$ paradigm or it is an indication that the mass estimates of clusters are dramatically more uncertain than we think.