Hallym University Research Articles

Analysis of Risk Factors for Conversion from Off-Pump to On-Pump Coronary Artery Bypass Graft.

BackgroundOff-pump coronary artery bypass (OPCAB) is performed worldwide, but significant risks are associated with conversion to on-pump surgery. Therefore, we evaluated the composite outcomes between an OPCAB group and a conversion group.MethodsFrom January 2008 to December 2012, 100 consecutive patients underwent OPCAB at Hallym University Sacred Heart Hospital, of whom 84 underwent OPCAB without adverse events (OPCAB group), and 16 were converted to on-pump surgery (conversion group). Early morbidity, early and long-term mortality, and major adverse cardiac and cerebrovascular events (MACCEs) were the primary and long-term composite endpoints.ResultsThe mean follow-up period was 55±26 months, with 93% of the patients completing follow-up. The composite outcomes in the OPCAB and conversion groups were as follows: early morbidity, 2.3% versus 12.5%; early mortality, 4.7% versus 0%; long-term mortality, 14.3% versus 25.0%; and MACCEs, 14.3% versus 18.8%, respectively. No composite endpoints showed statistically significant differences. Preoperative acute myocardial infarction (AMI) was identified as an independent risk factor for conversion (p=0.025).ConclusionThe conversion group showed no statistically significant differences in early mortality and morbidity, MACCEs, or long-term mortality compared with the OPCAB group. The preoperative diagnosis of AMI was associated with an increased number of conversions to on-pump surgery.

Sustainable Emission Control Policies: Viability Theory Approach

Kunhong Kim, Corresponding author, Professor, Department of Economics & Institute of Economy, Hallym University, 1 Hallymdaehak-gil, Chuncheon, Gangwon-do, 24252 Korea. (E-mail): kimku@hallym.ac.kr; Jacek B. Krawczyk, Adjunct Academic, School of Computer Science, Engineering and Mathematics, Flinders University, Australia. GPO Box 2100, Adelaide 5001, South Australia. (E-mail): jacek.krawczyk@flinders.edu.au.

Plasma Cell Cheilitis: A Clinicopathological and Immunohistochemical Study of 13 Cases

BackgroundPlasma cell cheilitis is an unusual benign plasma cell proliferative disease of an unknown etiology that typically presents on the lip.ObjectiveThe aim of this study was to investigate the clinicopathological characteristics of 13 cases of plasma cell cheilitis.MethodsThe present study investigated the clinical manifestations, treatment modalities, and outcome of 13 patients diagnosed with plasma cell cheilitis from 2011 to 2016 at Kangdong Sacred Heart Hospital and Hallym University Sacred Heart Hospital. Biopsy specimens of the all cases were evaluated using conventional hematoxylin and eosin staining with kappa and lambda immunoglobulin light chain immunohistochemistry.ResultsThe age of the patients ranged from 39 to 86 years (mean, 64.7 years), with male predominance. Histopathologically, 61.5% and 38.5% of patients showed band-like and pan dermal plasmacytic infiltrates, respectively. Eosinophilic infiltration was noted in 69.2% of patients. All cases showed both kappa and lambda immunoglobulin light chain reactivities, and kappa predominance was confirmed in 9 patients (69.2%). A majority of the patients was treated with local therapy, such as intralesional steroid injection with topical tacrolimus. Among the 13 patients, plasma cell cheilitis completely resolved, partially resolved, and recurred in 3 (23.1%), 5 (38.5%), and 5 patients (38.5%), respectively.ConclusionPlasma cell cheilitis presented as erosive edematous circumscribed patches or plaques affecting mainly the lower lip of elderly male patients. The majority of histopathology cases showed characteristic plasma cell aggregation on the upper dermis that was immunopositive for immunoglobulin light chain, with kappa predominance.

Does the discrepancy in histologic differentiation between a forceps biopsy and an endoscopic specimen necessitate additional surgery in early gastric cancer?

AIMTo investigate the clinicopathological variables in early gastric cancer (EGC) patients in relation to differentiation discrepancy.METHODSThe data of 265 specimens from 240 patients with EGC, who had undergone radical operation at Hallym University Sacred Heart Hospital from 2010 to 2015, were retrospectively analyzed. We evaluated clinical, endoscopic, and histopathological data according to histological discrepancy.RESULTSClinically significant discrepancy rate showed the difference in differentiated type (well and moderately differentiated) and undifferentiated type (poorly differentiated and signet ring cell) between endoscopic biopsies and postoperative specimens was 9.4% (25/265). There were no differences in tumor location, size, gross pattern, and number of biopsies. Specimens having histological discrepancy showed more submucosal invasion (72.0% vs 49.6%, P = 0.033) and lymph node involvement (24.0% vs 7.9%, P = 0.009) than specimens having non-discrepancy. The rate of a positive epidermal growth factor receptor status was higher in specimens having discrepancy than in specimens having non-discrepancy (81.0% vs 55.4%, P = 0.035).CONCLUSIONThe discordance of histologic differentiation is associated with higher submucosal invasion and lymph node metastases in EGC. Patients have histological discrepancy may require additional surgical treatments.

Frequency of Herpes Zoster Recurrence in Central District of Korea.

BackgroundHerpes zoster is characterized by unilateral grouped vesicles along the distribution of a dermatome. A global recurrence rate as low as 0.5%∼6.2% has been reported for herpes zoster. The recurrence of herpes zoster is higher in immunocompromised patients and older patients.ObjectiveThe purpose of this study is to assess the frequency of herpes zoster recurrence and factors that can influence its recurrence.MethodsFrom January 2005 to December 2015, 14,343 patients with herpes zoster were enrolled in this study. The patients were diagnosed at Hallym University Medical Centers and Kangwon National University Hospital in Seoul, Gyeonggi, and Gangwon. Herpes zoster recurrence and patient characteristics were surveyed by medical record review and a telephonic survey.ResultsThe overall frequency of herpes zoster recurrence was 1.18%. The frequency of recurrence was higher in women than in men. It was also higher in patients aged 50∼70 years than in patients who were younger or older than this. Additionally, we assessed that the frequency of recurrence was statistically higher in patients with a compromised immune system and in patients who experienced longer lasting pain during their first episode.ConclusionThe frequency of herpes zoster recurrence is more common in women, older age, patient with longer pain duration and immunocompromised patients.

Acid-base disorders after orthotopic bladder replacement: comparison of an ileal neobladder and an ileal conduit

Objectives: For many years, creation of an orthotopic neobladder after cystectomy has been popular. In the present study, we measured the extent of metabolic acidosis in patients with ileal neobladders compared with ileal conduits and defined risk factors for development of metabolic acidosis.Methods: We retrospectively studied 95 patients, who underwent radical cystectomy and urinary diversion to treat invasive bladder cancer from January 2001 to December 2014 at Hallym University Kangnam Sacred Heart Hospital, through investigation of acid-base balance, serum electrolyte levels and renal function one month and one year after operation.Results: One month after the operation, metabolic acidosis was found from 18 patients (31.0%) in an ileal neobladder group and from 4 (14.8%) in an ileal conduits group. One year after the operation, the numbers became 11 (22.9%) and 2 (10.0%), respectively. However, there was not a statistical difference. The blood biochemical profiles of the two groups did not differ significantly after urinary diversion. Logistic analysis revealed that lower estimated glomerular filtration rate (eGFR) was associated with metabolic acidosis at one month (odds ratio, OR = 0.94 [0.91–0.97]; p < 0.001) and one year (OR = 0.94 [0.92–0.97]; P = 0.001) after urinary diversion. In multivariate analysis, lower eGFR is a significant risk factor for metabolic acidosis at one month.Conclusions: Patients with ileal neobladders and conduits are at the similar risk of metabolic acidosis. A close association between renal function and development of metabolic acidosis was observed, especially stronger in an early period after operation.

Correlation of vitamin D levels with tear film stability and secretion in patients with dry eye syndrome.

To investigate tear film stability and secretion according to serum 25-hydroxyvitamin D3 [25(OH)D] levels in dry eye patients. In this retrospective observational study, the medical charts of 92 patients who visited the Department of Ophthalmology at Hallym University Kangnam Sacred Heart Hospital from April to August 2015 were reviewed. Serum 25(OH)D levels were measured. Subjects were divided into three groups according to serum 25(OH)D levels: sufficient, inadequate or deficient group. Eye discomfort was measured by ocular surface disease index (OSDI). Tear break-up time (TBUT), fluorescein staining score and Schirmer's tear secretion test were measured. The mean age was 53.38±13.69years. Mean serum 25(OH)D level was 14.41±5.98ng/ml. Tear break-up time (TBUT) and tear secretion were positively correlated with serum 25(OH)D levels (r=0.389, p=0.001; and r=0.428, p<0.001, Pearson correlation test). Tear break-up time (TBUT) and tear secretion were shorter in the vitamin D-deficient group compared to the sufficient group (p=0.022 and p=0.004). Fluorescein staining scores and OSDI scores were not different between the three groups. Tear break-up time (TBUT) and secretion were correlated with serum vitamin D levels. Vitamin D status may be an important factor for dry eye syndrome.

New insight into the analysis of amniotic fluid microflora using 16S rRNA gene sequencing

Introduction: Intra-uterine infection is a major cause of spontaneous pre-term birth before 30 weeks of gestation. In addition, intra-amniotic inflammation is present in approximately 80 % of patients with acute cervical insufficiency. The microbiome is known to cause intra-amniotic infection causing pre-term birth. Recently, surveys of the microbial communities in the vagina or in amniotic fluid using sequencing of the 16s rRNA gene have been carried out. Here, we reported the microbiome compositions in mid-trimester amniotic fluids in two pregnant women with cervical insufficiency identified using 16S rRNA sequencing. Case presentation: A 35-year-old primipara and a 37-year-old nullipara were admitted to Hallym University Medical Center, Korea. They were negative for nitrazine and Actim PROM (Medix Biochemica) tests, and their amniotic membranes had prolapsed beyond the external os. A physical examination indicated that cerclage using a uniconcave balloon should be carried out, and amnioreduction was performed. Thereafter, they delivered at very early pre-term birth of below 24 weeks and the birth outcomes were pre-natal death. Analysis of mid-trimester amniotic fluids in these two pregnant women with cervical insufficiency identified Sneathia sanguinegens and Fusobacterium nucleatum. These bacteria were not identified using vaginal or amniotic cultures. Conclusion: These results suggest that 16S rRNA gene sequencing can be used to identify the predominant microbiome causing pre-term birth in pregnant women with cervical insufficiency. Further studies are needed in large samples to improve our understanding of microbes causing pre-term birth and to prevent pre-term birth in pregnant women with cervical insufficiency.

Could laparoscopic appendectomy in pregnant women affect obstetric outcomes? A multicenter study.

The purpose of this study was to compare the perioperative and obstetric outcomes of pregnant women between laparoscopic surgery and open surgery and to evaluate the predictive factors for overall obstetric outcomes. We retrospectively reviewed the medical records of pregnant women who underwent appendectomy between January 2008 and June 2015 at six hospitals affiliated to Hallym University. Eighty patients were evaluated. Twenty-four underwent laparoscopic appendectomy (LA) and 56 underwent open appendectomy (OA). There were no significant differences in the patients' characteristics and gestational age at surgery between the two groups. Operation time, time to flatus, and time to soft food intake were similar in both groups. The length of stay was shorter in the LA group than in the OA group (5.1 vs 8.1days, P = 0.044). Gestational age at delivery, birth weight, and delivery type were similar in both groups. There was no significant difference in overall obstetric poor outcome (20.8 vs 14.3%, P = 0.516), including preterm delivery (8.3 vs 7.1%, P = 1.000) and fetal loss (12.5 vs 7.1%, P = 0.350). Multivariable analysis revealed that fever >38°C (P = 0.022) and maternal age (P = 0.044) were independent predictors for the overall poor outcomes. LA was associated with shorter length of stay compared with OA, but perioperative and obstetric outcomes were similar with both procedures. LA can be safely performed in pregnant women in any trimester.

Right middle lobe syndrome caused by eosinophilic mucoid impaction in adults

Ha Won Hwang, Joo-Hee Kim, Suk Yeon Kim, Sun Ho Lee, Soo Haeng Lee, Sunghoon Park, Yong Il Hwang, Seung Hun Jang, Ki-Suck Jung, In Jae Lee Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Internal Medicine, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang; Department of Radiology, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang, Korea

Fabrication and characterization of hydrocolloid dressing with silk fibroin nanoparticle for wound healing

Event Abstract Back to Event Fabrication and characterization of hydrocolloid dressing with silk fibroin nanoparticle for wound healing Ok Joo Lee1, Ju Yeon Jung1, Gilson Khang2 and Chan Hum Park1, 3 1 Hallym University, Nano-Bio Regenerative Medical Institute, Korea 2 Chonbuk National University, Department of BIN Fusion Technology, Korea 3 Chuncheon Sacred Heart Hospital, Departments of Otorhinolaryngology-Head and Neck Surgery, Korea Hydrocolloid dressings have been developed for many types of wound healing. In particular, dressing is a critical component in the successful recover of burn injuries, which causes a great number of people to not only suffer from physical but also psychological and economic anguish each year. Additionally, silk fibroin is the safest material for tissue engineering due to biocompatibility. In this study, we fabricated hydrocolloid dressings incorporating silk fibroin nanoparticles to enhance the efficacy of hydrocolloid dressing and then use this silk fibroin nanoparticle hydrocolloid dressing (SFNHD) in animal models to treat burn wounds. The structures and properties of SFNHD were characterized using tensile strength and cck-8 assay. The results indicated the structural stability and the cellular biocompatibility of the hydrocolloid dressing suggesting that SFNHD can be applied to the treatment of wounds. To demonstrate the capacity of a silk fibroin hydrocolloid dressing to treat burn wounds, we compared SFNHD to gauze and Neoderm®, a commercially available dressing. This study clearly demonstrated accelerated wound healing with greater wound structural integrity and minimal wound size after treatment with SFNHD. These observations indicate that SFNHD may be an improvement upon current standard dressings such as Gauze and Neoderm® for burn wounds. and Cooperative Research Program for Agriculture Science & Technology Development (Project No.PJ011214022015), Rural Development Administration, Republic of Korea.

Characterization of Silk/�-Tricalcium Phosphate Scaffolds for the Bone Tissue Engineering

Event Abstract Back to Event Characterization of Silk/β-Tricalcium Phosphate Scaffolds for the Bone Tissue Engineering Gilson Khang1, Dae Hoon Lee1, Jae Hun Shin1, Jeong Eun Song1 and Chan Hum Park2 1 Chonbuk National University, BIN convergence technology, Korea 2 College of Medicine, Hallym University, Otorhinolaryngology-Head and Neck Surgery, Chuncheon Sacred Heart Hospital, Korea Silk is a potential material for biomedical applications because it has several attractive properties such as biocompatibility and biodegradability. However, it has a lack of mechanical properties for bone replacement graft material. To increase osteoconductivity and osteoinductivity, we modified the mechanical property and osteoconductivity of silk with β-Tricalcium Phosphate (β-TCP). β-TCP has degradable, osteoconductive and minimal cytotoxicity. We checked the physical and chemical characterizations of silk/β-TCP scaffolds using SEM, compressive strength, and FT-IR, etc. Also, osteogenic differentiation of rabbit bone marrow mesenchymal stem cells (rBMSCs) cultured in scaffold was evaluated by using alkaline phosphatase (ALP), MTT, RT-PCR, and SEM. These results showed that silk/β-TCP (25:75) scaffold increased cell proliferation and differentiation of rBMSCs in vitro for 1 to 4 weeks. Also, histology result from implantation showed the same of them. From these results, it could be suggested that silk/β-TCP (25:75) scaffold is applied to one of useful biomaterials in terms of bone regeneration. Bio-industry Technology Development Program (112007-05-1-SB010), Technology Commercialization Support Program (814005-03-1-HD020), Ministry for Food, Agriculture, Forestry and Fisheries, Republic of Korea. Keywords: Cell Differentiation, Regenerative Medicine, in vitro, biomaterial Conference: 10th World Biomaterials Congress, Montréal, Canada, 17 May - 22 May, 2016. Presentation Type: Poster Topic: Biomaterials in constructing tissue substitutes Citation: Khang G, Lee D, Shin J, Song J and Park C (2016). Characterization of Silk/β-Tricalcium Phosphate Scaffolds for the Bone Tissue Engineering. Front. Bioeng. Biotechnol. Conference Abstract: 10th World Biomaterials Congress. doi: 10.3389/conf.FBIOE.2016.01.00362 Copyright: The abstracts in this collection have not been subject to any Frontiers peer review or checks, and are not endorsed by Frontiers. They are made available through the Frontiers publishing platform as a service to conference organizers and presenters. The copyright in the individual abstracts is owned by the author of each abstract or his/her employer unless otherwise stated. Each abstract, as well as the collection of abstracts, are published under a Creative Commons CC-BY 4.0 (attribution) licence (https://creativecommons.org/licenses/by/4.0/) and may thus be reproduced, translated, adapted and be the subject of derivative works provided the authors and Frontiers are attributed. For Frontiers’ terms and conditions please see https://www.frontiersin.org/legal/terms-and-conditions. Received: 27 Mar 2016; Published Online: 30 Mar 2016. Login Required This action requires you to be registered with Frontiers and logged in. To register or login click here. Abstract Info Abstract The Authors in Frontiers Gilson Khang Dae Hoon Lee Jae Hun Shin Jeong Eun Song Chan Hum Park Google Gilson Khang Dae Hoon Lee Jae Hun Shin Jeong Eun Song Chan Hum Park Google Scholar Gilson Khang Dae Hoon Lee Jae Hun Shin Jeong Eun Song Chan Hum Park PubMed Gilson Khang Dae Hoon Lee Jae Hun Shin Jeong Eun Song Chan Hum Park Related Article in Frontiers Google Scholar PubMed Abstract Close Back to top Javascript is disabled. Please enable Javascript in your browser settings in order to see all the content on this page.

Development of a More Effective Hearing Screening Questionnaire for Infants and Children during Medical Check-Ups

Jiyoung Lee, Jihye Rhee, Su-Kyoung Park, Jiwon Chang, Jin-Sook Kim, Kyoung Ho Park, Hyong Ho Cho, Jun Ho Lee, Son Moon Shin, and Moo Kyun Park Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University Hospital, Seoul National University College of Medicine, Seoul; and Department of Otorhinolaryngology-Head and Neck Surgery, Hallym University College of Medicine, Seoul; and Department of Audiology, Hallym University, Chuncheon; and Department of Otolaryngology-Head and Neck Surgery, College of Medicine, The Catholic University of Korea, Seoul; and Department of Otolaryngology-Head and Neck Surgery, Chonnam National University Medical School, Gwangju; and Department of Pediatrics, Cheil Hospital, Seoul, Korea

Health Group and Disease Group's Perceptions of Health and Health-related Quality of Life: a Focus Group Study and In-depth Interviews

Hyeon-Jeong Lee, Minsu Ock, Soo Young Kim, Seon-Ha Kim, Sun Hee Kim, Min-Woo Jo Department of Preventive Medicine, University of Ulsan College of Medicine, Seoul, Korea Department of Family Medicine, Hallym University College of Medicine, Anyang, Korea Department of Nursing, Dankook University College of Health Sciences, Cheonan, Korea Department of Family Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea

Analysis of Risk Factor for the Development of Chronic Subdural Hematoma in Patients with Traumatic Subdural Hygroma.

ObjectiveAlthough a high incidence of chronic subdural hematoma (CSDH) following traumatic subdural hygroma (SDG) has been reported, no study has evaluated risk factors for the development of CSDH. Therefore, we analyzed the risk factors contributing to formation of CSDH in patients with traumatic SDG.MethodsWe retrospectively reviewed patients admitted to Hallym University Hospital with traumatic head injury from January 2004 through December 2013. A total of 45 patients with these injuries in which traumatic SDG developed during the follow-up period were analyzed. All patients were divided into two groups based on the development of CSDH, and the associations between the development of CSDH and independent variables were investigated.ResultsThirty-one patients suffered from bilateral SDG, whereas 14 had unilateral SDG. Follow-up computed tomography scans revealed regression of SDG in 25 of 45 patients (55.6%), but the remaining 20 patients (44.4%) suffered from transition to CSDH. Eight patients developed bilateral CSDH, and 12 patients developed unilateral CSDH. Hemorrhage-free survival rates were significantly lower in the male and bilateral SDG group (log-rank test; p=0.043 and p=0.013, respectively). Binary logistic regression analysis revealed male (OR, 7.68; 95% CI 1.18–49.78; p=0.033) and bilateral SDG (OR, 8.04; 95% CI 1.41–45.7; p=0.019) were significant risk factors for development of CSDH.ConclusionThe potential to evolve into CSDH should be considered in patients with traumatic SDG, particularly male patients with bilateral SDG.

Lymphovascular invasion in more than one-quarter of small rectal neuroendocrine tumors.

AIMTo identify the frequency, clinicopathological risk factors, and prognostic significance of lymphovascular invasion (LVI) in endoscopically resected small rectal neuroendocrine tumors (NETs).METHODSBetween June 2005 and December 2015, 104 cases of endoscopically resected small (≤ 1 cm) rectal NET specimens at Hallym University Sacred Heart Hospital in Korea were retrospectively evaluated. We compared the detected rate of LVI in small rectal NET specimens by two methods: hematoxylin and eosin (H&E) and ancillary immunohistochemical staining (D2-40 and Elastica van Gieson); in addition, LVI detection rate difference between endoscopic procedures were also evaluated. Patient characteristics, prognosis and endoscopic resection results were reviewed by medical charts.RESULTSWe observed LVI rates of 25.0% and 27.9% through H&E and ancillary immunohistochemical staining. The concordance rate between H&E and ancillary studies was 81.7% for detection of LVI, which showed statistically strong agreement between two methods (κ = 0.531, P < 0.001). Two endoscopic methods were studied, including endoscopic submucosal resection with a ligation device and endoscopic submucosal dissection, and no statistically significant difference in the LVI detection rate was detected between the two (26.3% and 26.8%, P = 0.955). LVI was associated with large tumor size (> 5 mm, P = 0.007), tumor grade 2 (P = 0.006). Among those factors, tumor grade 2 was the only independent predictive factor for the presence of LVI (HR = 4.195, 95%CI: 1.321-12.692, P = 0.015). No recurrence was observed over 28.8 mo regardless of the presence of LVI.CONCLUSIONLVI may be present in a high percentage of small rectal NETs, which may not be associated with short-term prognosis.

Association between Health Literacy, Diabetes Knowledge, and Glycemic Control in Diabetic Patients

Purpose: Patients with limited health literacy usually have less disease-related knowledge, and consequently have poor health status. On the other hand, diabetes care requires complex course of strict medication and lifestyle changes to maintain appropriate glycemic levels and to prevent diabetic complications. We evaluated the association between health literacy, diabetes knowledge and glycemic control among diabetic patients. Methods: A cross-sectional study of 84 enrollees who were older than 30 years and had type 2 diabetes was conducted in a university hospital. Health literacy was measured using the short form of Newest Vital Sign (NVS), and diabetes knowledge measured using one of the two parallel diabetes knowledge tests. Participants were interviewed to determine participants’ characteristics, and HbA1c levels were identified from the clinical database of Hallym University Kang Nam Sacred Heart Hospital to assess glycemic control. Results: The mean score of health literacy was 1.8 (±1.9) and mean score of diabetes knowledge was 12.0 (±4.1). Only 23.8% of participants had adequate literacy. After adjusting sociodemographic characteristics, duration of diabetes, and treatment regimen, diabetes knowledge and health literacy were not independently associated with HbA1c levels. Only significant factor of glycemic control was duration of diabetes (r=0.489, p<0.001). Conclusion: Among patients with type 2 diabetes, health literacy and diabetes knowldege were not independently associated with glycemic control. Better strategies are needed to improve glycemic control.

Orbital and Periorbital Complications of Proton Beam Radiation Therapy for Intraocular Tumor

Orbital and Periorbital Complications of Proton Beam Radiation Therapy for Intraocular Tumor Y.J. Choi, S. Kim, H.K. Choung, and Y.S. Yu; Department of Ophthalmology, Kangdong Sacred Heart Hospital, Hallym University Medical Center, Seoul, South Korea, Department of Radiation Oncology, Seoul Metropolitan Government Seoul National University Boramae Medical Center, Seoul, South Korea, Department of Ophthalmology, Seoul Metropolitan Government Seoul National University Boramae Medical Center, Seoul, South Korea, Department of Ophthalmology, College of Medicine, Seoul National University, Seoul, Korea, Seoul, South Korea, Department of Ophthalmology, Seoul National University Hospital, Seoul, Korea, Seoul, South Korea

IDH-1 Mutation Status Predicts for Better Overall Survival in Patients With Primary Glioblastoma Receiving Radiation and Temozolomide

Orbital and Periorbital Complications of Proton Beam Radiation Therapy for Intraocular Tumor Y.J. Choi, S. Kim, H.K. Choung, and Y.S. Yu; Department of Ophthalmology, Kangdong Sacred Heart Hospital, Hallym University Medical Center, Seoul, South Korea, Department of Radiation Oncology, Seoul Metropolitan Government Seoul National University Boramae Medical Center, Seoul, South Korea, Department of Ophthalmology, Seoul Metropolitan Government Seoul National University Boramae Medical Center, Seoul, South Korea, Department of Ophthalmology, College of Medicine, Seoul National University, Seoul, Korea, Seoul, South Korea, Department of Ophthalmology, Seoul National University Hospital, Seoul, Korea, Seoul, South Korea

Hospital mode of death in therapeutic hypothermia-treated out-of-hospital cardiac arrest patients who withdrawal of life-sustaining treatment were not applied

Seung Joon Lee1,∗, Young-Min Kim2, Ji-Hoon Kim1, In Soo Cho3, Giwoon Kim4, Ji Hyeon Hwang2, Gyu Chong Cho5 1 Department of Emergency Medicine, Myongji Hospital, Goyang, Gyeonggi-do, Republic of Korea 2 Department of Emergency Medicine, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea 3 Department of Emergency Medicine, KEPCO Medical Center, Seoul, Republic of Korea 4 Department of Emergency Medicine, College of Medicine, Ajou University, Suwon, Gyeonggi-do, Republic of Korea 5 Department of Emergency Medicine, Kangdong Sacred Heart Hospital, Hallym University, Seoul, Republic of Korea