ObjectiveThe aim was to outline the relationship between female pattern hair loss (FPHL) and metabolic syndrome (MetS).BackgroundSeveral studies have examined the association of MetS with hair loss in men, whereas there were scanty studies focusing on female sex association, especially in Egypt.Participants and methodsThis prospective study was carried out on 30 women with different stages of FPHL and 30 age-matched and sex-matched healthy women as controls.ResultsAmong the cases group, the majority of them (70%) had not been diagnosed with MetS. There was a significant difference in fasting blood glucose, total cholesterol, low-density lipoprotein cholesterol, systolic blood pressure (BP), diastolic BP, and waist circumference between both groups (P = 0.002, <0.001, <0.001, <0.001, <0.001, and 0.002, respectively). There was a significant relation between MetS and Ludwig's classification, fasting blood glucose, triglycerides, total cholesterol, low-density lipoprotein cholesterol, systolic BP, diastolic BP, and waist circumference (P < 0.001, 0.029, 0.021, <0.001, <0.001, <0.001, <0.001, and 0.029, respectively).ConclusionThere was a significant correlation between MetS components, especially waist circumference and hypertension, and FPHL.