City Of Guadalajara Research Articles

Abstract 2761: Evaluation of the BOADICEA model for predicting BRCA1 and BRCA2 mutation carrier probabilities in high-risk US Hispanic and Mexican families: A report from the Clinical Cancer Genetics Community Research Network

Abstract Background: BRCA1 and BRCA2 (BRCA) mutation prediction models are low cost tools that enable clinicians to target individuals with a higher probability to carry mutations in the BRCA genes. Most of the data used to construct these models were derived from a predominantly non-Hispanic White population. The predictive accuracy of these models in diverse populations is unclear. The Breast and Ovarian Analysis of Disease Incidence and Carrier Estimation Algorithm (BOADICEA) was developed using population-based families with multiple affected individuals that were primarily from the UK. The purpose of this study was to investigate and compare the accuracy of BOADICEA for prediction of BRCA mutation status among US Hispanics and a cohort of Mexicans in Guadalajara and Mexico City. Methods: Hispanic patients undergoing genetic cancer risk assessment (GCRA) were enrolled in an IRB-approved prospective registry from sites within the Clinical Cancer Genetics Community Research Network (CCGCRN), comprised of the City of Hope and 47 collaborating sites representing primarily community-based oncogenetic practices across the US and Latin America, including two cancer institutes in Mexico (University of Guadalajara; Instituto Nacional de Cancerología, Mexico City). Pedigrees were created in Progeny, exported to text files, and then uploaded for probablity calculations according to BOADICEA version 3 guidelines. Accuracy was assessed using an observed versus expected and an area under the receiver operating characteristic (ROC) curve analysis. Results: Overall, BOADICEA performed better in US Hispanics (area under the curve [AUC] = 0.75) for predicting a BRCA mutation than in the Mexican cohort (AUC = 0.64; p-value = 0.0015). Although BRCA mutations were documented in 238 of 1,247 (19.1%) US Hispanics and 23 of 234 (9.8%) Mexicans, BOADICEA predicted a mean mutation probability of 10.3% and 5.6%, respectively. Summary: Though generally the best performing model, BOADICEA's ability to predict BRCA mutations has been investigated in previous studies with different populations with varying results. The lower performance of BOADICEA in the Mexican cohort could be a result of the limitations in pedigree data. It's possible that families don't share information about cancer due to cultural norms or fear of stigmitation. It is also possible that the model assumptions about population mutation frequency are inaccurate. The results of this study indicate the need to document the clinical reliability of probability models when evaluating high risk US Hispanics and patients in Mexico. Citation Format: Jessica Clague, Cynthia Villarreal-Garza, Adrian Daneri Navarro, Alexandra J. Obregon-Tito, Sharon Sand, Tanya A. Chavez, Bita Nehoray, Lacolle Robinson, Lenny Gallardo, Azucena Del Toro, Rosa Alvarez, Kathleen R. Blazer, Blu Yanez, Charité Ricker, Gary W. Unzeitig, Kai Yang, Jeffrey N. Weitzel. Evaluation of the BOADICEA model for predicting BRCA1 and BRCA2 mutation carrier probabilities in high-risk US Hispanic and Mexican families: A report from the Clinical Cancer Genetics Community Research Network. [abstract]. In: Proceedings of the 106th Annual Meeting of the American Association for Cancer Research; 2015 Apr 18-22; Philadelphia, PA. Philadelphia (PA): AACR; Cancer Res 2015;75(15 Suppl):Abstract nr 2761. doi:10.1158/1538-7445.AM2015-2761

MTT-S Mexico Trip: Addressing the RF and Microwave Community in Mexico [Around the Globe

This article focuses on a recent IEEE Microwave Theory and Techniques Society (MTT-S) initiative, conceived by the Membership and Geographical Activities Committee (MGA-C) of the Society’s Administrative Committee (AdCom). Its aim is to develop membership, a volunteer base, and engagement in MTT-S activities in a targeted area of Region 9 (Latin America), namely Mexico. The highlight of the initiative was a trip to the area by a delegation of enthusiastic volunteers who visited Guadalajara, Puebla, and Mexico City to reach out to the RF and microwave community in Mexico, including members and potential members of the MTT-S.

“Demolición de la trinidad” boceto de Jenaro Pérez Villaamil. Documento fundamental para conocer la antigua iglesia de Santiago de Guadalajara

<p>La ciudad de Guadalajara contó hasta el siglo XIX con diez templos parroquiales, que unidos a los catorce conventos y un gran número de otro tipo de edificios religiosos hacían de la función religiosa una de las más importantes de la ciudad.</p><p>Desamortización, supresión de parroquias, guerras y desidia hicieron que gran parte del patrimonio arquitectónico religioso se perdiera.</p><p>Uno de estos edificios desaparecidos fue el antiguo templo parroquial de Santiago.</p><p>Gracias a los documentos gráficos conservados, pero fundamentalmente gracias a un boceto a mano alzada de Jenaro Pérez Villaamil podemos aproximarnos a las características arquitectónicas y constructivas de este edificio.</p>

Decisiones públicas sin diálogo público: análisis de los argumentos sobre el caso de la Vía Exprés vertidos en la prensa de Guadalajara

Este artículo presenta cómo se discutió la posible realización de una obra pública en Guadalajara. La obra, que no fue realizada, enfrentó a actores políticos y sociales. La investigación estudió cómo se construyó el diálogo público en cuatro diarios. A través del análisis de contenido de notas y opiniones publicadas y de los argumentos vertidos en ellas, los autores dan cuenta de la baja calidad del diálogo público.

Un informe de Pedro de Ribera para Nueva España: el abastecimiento de agua a Guadalajara

The project proposed by the Franciscan architect Pedro Antonio de Buzeta to supply water to the New Spanish city of Guadalajara was sent to Madrid for review and supervision by the Council of the Indies. The Madrid architect Pedro de Ribera dealt with its technical aspects, and in 1735 he wrote an interesting critique of the plan. Among other questions, he defended the use of underground aqueducts, demonstrated his erudition and considered diverse improvements to Buzeta’s project.

Innovation Results and Customer Knowledge Management in MMxico

Innovation in different Stages (INNOVS) is considered an important driver to create and increase the competitive advantage (OECD, 2005; White & Bruton, 2011; INSEAD, 2013; Dussauge et al, 1992; Hill J Canibano, et. al., 1999). Moreover, recent research (Gibbert, et al., 2002; Gebert et al. 2013) shows that driving the knowledge in the sense to obtain more precise information: for, from and about of the customers, the firms are more likely to sense emerging market opportunities before their competitors; this is called Customer Knowledge Management (CKM); so the question is: ?how can innovation results or outcome items (IOIT as a stage of INNOVS), be improved by customer knowledge?. As a Hypothesis we proposed: given the CKM importance, this is present in at least on 50% of the variability of IOIT or innovation results.This paper is aimed to resolve this; we proposed a conceptual model applied to the total population: 200 CEOs of the software developer sector in Guadalajara City, Jalisco, Mexico (SDSGC). This model involves 4 independent variables/12 Dimensions/33 indicators from CKM with INNOVS that involves 6 independent variables/33 Dimensions/77 indicators. With this, we demonstrated the validity of the questionnaire what was designed on the Likert scale. After this, a pilot questionnaire was applied on a sample of 20 CEO as respondents and demonstrated its confidence using Cronbach's alpha for confidence test and running Multiple Regression Analysis (MRA) by Stepwise Method, to prove each variable to contrast.The results obtained, allow us to measure the correlation level between the variables in study to discover CKMADI (CKM as a Driver of Innovation) and CKMS (CKM Support) are influencing the IOIT, between 36.5% and 40.3%. Therefore, this is the importance to integrate and increase them as competitive advantages in the SDSGC.

Type of Innovation and Customer Knowledge Management, in Mexico

The Type of Innovation as an Innovation Process component, increases the competitive advantage of the firms. The Customer Knowledge Management, influences the Firm´s Process Innovation, based on the sense of information: for, from and about the customers, that increase the market opportunities. Hence, the aim of this paper is to determine the model and the most significant indicators from the Type of Innovation related with Customer Knowledge Management. We questioned 200 CEOs from the Software Developer Sector in Guadalajara City, Mexico and by Using of the Inferential Statistics, we found only 2 relevant indicators from 7, situation that might be improved to rise new competitive advantages.

Agua para las ciudades en el porfiriato. El caso de Guadalajara, México

La argumentación principal del trabajo es que durante el porfiriato se construyó la imagen moderna del agua en las ciudades, que incluyó cambios tecnológicos y en el patrón de consumo, nuevas formas de gestión y regulación institucional, así como una nueva significación y valoración del recurso. En realidad, la relación sociedad-agua se transformó en sus dimensiones socioculturales, tecnológicas, legales y administrativas, entre otras. El análisis histórico permite examinar las permanencias y rupturas de una sociedad en un tiempo y espacio determinado. De allí el interés de estudiar la ciudad de Guadalajara en un periodo de importantes transformaciones en la relación con el agua que sentaron las bases para su modernización: la urbanización e industrialización del siglo xx. Sin embargo, el modelo sanitario de abastecimiento y disposición de desechos finales fue el origen de la crisis contemporánea del agua en la ciudad, que se basó en una demanda creciente del recurso frente a una disposición limitada de las fuentes locales. La solución fue el aprovechamiento del agua de fuentes no locales cada vez más lejanas (otras cuencas), con todos los impactos sociales y ambientales asociados.

Ante las seguridades evanescentes: Riesgo y subjetividades en la ciudad de Guadalajara

This article presents the results of an ethnographic research into the ways in which the risks inherent to modernity shape subjectivities in the city of Guadalajara in different social positions. The analysis focuses on the subjects’ relationship with State institutions, work and family; on the meanings and practices that appear in the context of urban daily life marked by the expansion of the ominous; and on the conceptions of community in the context of risk. The risk is revealed as a control apparatus with a strong individualizing power, able to weaken the social agency and to exacerbate the precariousness of the common.

Ante las seguridades evanescentes. Riesgo y subjetividades en la ciudad de Guadalajara

This article presents the results of an ethnographic research into the ways in which the risks inherent to modernity shape subjectivities in the city of Guadalajara in different social positions. The analysis focuses on the subjects’ relationship with State institutions, work and family; on the meanings and practices that appear in the context of urban daily life marked by the expansion of the ominous; and on the conceptions of community in the context of risk. The risk is revealed as a control apparatus with a strong individualizing power, able to weaken the social agency and to exacerbate the precariousness of the common.

Leadership and Value Creation on Innovation: The Case of Software Developer Sector in Guadalajara, MMxico

This document is a descriptive study that aims to discover and analyze the elements that characterize the leadership oriented to value creation and development of innovation in organizations. The methodology is based on the application of Short Multifactor Leadership Questionnaire (MLQ 5X) of Avolio & Bass, (2004), for discovering the predominant type of leadership as; Transformational(LTRF), Transactional (LTRS), Passive/Avoidant (LPAV), and their results (RLDS) characterized with 45 indicators, and their incidence to the Value Creation (VC,8), Innovation Generation (IG,50), add up 103 indicators, describing 36 dimensions and 9 variables. The questionnaire was applied to 200 managers belonging to firms of the Software Developer Sector (SDS), as subject of study in Guadalajara City, Mexico (GCM). The study concluded with the discovery of LTRF as a predominant leadership in SDS, with positive correlation with VC and IG. LPAV, has an opposite correlation, mainly with VC (11%).

Innovation Generation and Leadership on Value Creation: The Case of Software Developer Sector in Guadalajara, MMxico

This document is a descriptive and correlational study that aims to discover and analyze the elements that characterize the Innovation Generation (IG) and leadership (LD) on Value Creation (VC) in the organizations. The methodology is based on the application of Oslo Manual Statements (2005) and other authors around IG, and the Manual Short Multifactor Leadership Questionnaire (MLQ 5XLD) of Avolio & Bass, (2004), for discovering the predominant components about IG, and the LD type: Transformational (TRFL), Transactional (TRSL), Passive / Avoidant (PAVL) throughout the VC accomplishment. The final model, is described with 45 indicators for MLQ5xLD, 50 indicators for IG, and VC with 8 indicators, add up 103 indicators, with 36 dimensions and 9 variables. The final questionnaire was applied to 200 managers belonging to firms of the Software Developer Sector (SDS), as a study subject in Guadalajara City, Mexico (GCM). The study concluded with the discovery of TRSL (.213) as a predominant MLQ5XLD and Output Items.

Las tribus futboleras en la ciudad de Guadalajara: las barras de los equiposAtlas y Guadalajara en la actualidad

Los grupos de aficionados al futbol denominados barras pueden caracterizarse como nuevas tribus urbanas amalgamadas por una fuerte vinculación emocional: la pasión compartida por un equipo de futbol. Este artículo, basado en entrevistas a líderes, muestra diferentes aspectos de algunos de estos colectivos que en la actualidad apoyan a los equipos Atlas y Guadalajara en la ciudad de Guadalajara: su origen, desarrollo, composición social, generacional y de género; su estructuración y relaciones internas, sus relaciones externas. Al mismo tiempo, se trata de comprender el papel que juega la afición de los miembros de estos grupos, en especial de sus líderes, en diferentes ámbitos de su vida cotidiana.

Customer Knowledge to Improve the Innovation: The Relationship in MMxico.

The Knowledge Management (KM) improves the innovation in the firms based on information (OECD, 2003). Gebert, Geib, Kolbe, & Riempp, (2013) showed the sense of information: for, from and about the customers, that increase the market opportunities; this is called Customer Knowledge Management (CKM). The different Innovation Stages (INNOVS) increase the competitive advantage (OECD, 2005). Hence: ?Which is the conceptual model that relates the variables, dimensions and indicators from CKM with INNOVS? A questionnaire was designed using Likert scale and the Cronbach's alpha for confidence measurement, Pearson's Correlation and Multiple Regression Analysis (MRA) with stepwise method, was applied in 200 SME's belonging to the software developer sector located in Guadalajara City (SDSGC), Mexico. Independent variables are based on CKM to explain the dependent variable INNOVS. CKM as a Driver Innovation (CKMADI) and CKM other sources of Knowledge (CKMOSK) on INNOVS showed correlation.

Infraestructura hidráulica en Guadalajara para el abastecimiento de agua potable: el caso de sustentabilidad en las galerías filtrantes de Guadalajara

En el presente artículo se analiza la construcción de la infraestructura hidráulica para el abastecimiento de agua a la ciudad de Guadalajara y su continuidad, específicamente, la primera obra que permitió el abastecimiento de agua de manera colectiva; las galerías filtrantes, que basan su funcionamiento en aguas phreáticas y subterráneas. A su vez se describe la región hidrológica de Guadalajara y la importancia de los actores sociales que participaron en su construcción, así como la tecnología utilizada, que hicieron posible llevar agua a la ciudad. Por otra parte, se da seguimiento, en el tiempo, de las galerías filtrantes y su impacto en las zonas de extracción, sustentabilidad y permanencia de éstas como fuente de abastecimiento para la ciudad, considerando la riqueza de sus acuíferos, los cuales han sido olvidados o no tomados en cuenta por cuestiones políticas y económicas.

Seismicity at the northeast edge of the Mexican Volcanic Belt (MVB) and activation of an undocumented fault: the Peñamiller earthquake sequence of 2010–2011, Querétaro, Mexico

Abstract. The town of Peñamiller in the state of Querétaro, Mexico, is located at the northeast border of the seismogenic zone known as the Mexican Volcanic Belt (MVB), which transects the central part of Mexico with an east–west orientation. In the vicinity of this town, a sequence of small earthquakes occurred during the end of 2010 and beginning of 2011. Seismicity in the continental regimen of central Mexico is not too frequent; however, it is known that there are precedents of large earthquakes (Mw magnitude greater than 6.0) occurring in this zone. Three large earthquakes have occurred in the past 100 yr: the 19 November 1912 (MS = 7.0), the 3 January 1920 (MS = 6.4), and the 29 June 1935 (MS = 6.9) earthquakes. Prior to the instrumental period, the earthquake of 11 February 1875, which took place near the city of Guadalajara, caused widespread damage. The purpose of this article is to contribute to the available seismic information of this region. This will help advance our understanding of the tectonic situation of the central Mexico MVB region. Twenty-four shallow earthquakes of the Peñamiller seismic sequence of 2011 were recorded by a temporary accelerograph network installed by the Universidad Autónoma de Querétaro (UAQ). The data were analyzed in order to determine the source locations and to estimate the source parameters. The study was carried out through an inversion process and by spectral analysis. The results show that the largest earthquake occurred on 8 February 2011 at 19:53:48.6 UTC, had a moment magnitude Mw = 3.5, and was located at latitude 21.039° and longitude −99.752°, at a depth of 5.6 km. This location is less than 7 km away in a south-east direction from downtown Peñamiller. The focal mechanisms are mostly normal faults with small lateral components. These focal mechanisms are consistent with the extensional regimen of the southern extension of the Basin and Range (BR) province. The source area of the largest event was estimated to have a radius of 0.5 km, which corresponds to a normal fault with azimuth of 174° and an almost pure dip slip. Peak ground acceleration (PGA) was close to 100 cm s−2 in the horizontal direction. Shallow earthquakes induced by crustal faulting present a potential seismic risk and hazard within the MVB, considering the population growth. Thus, the necessity to enrich seismic information in this zone is very important since the risk at most urban sites in the region might even be greater than that posed by subduction earthquakes.

Abastecimiento de agua potable en las ciudades de México: el caso de la zona metropolitana de Guadalajara

El abastecimiento de agua potable en México ha seguido un mismo patrón en la gestión de los recursos hídricos privilegiando a las zonas urbanas y a la industria, impactando en su zona de influencia a través del modelo de abastecimiento lejano, el cual no contempla medidas compensatorias para la región de donde se extrae dicho recurso.El objetivo de este documento es analizar el modelo de gestión que tuvo el abastecimiento y distribución del agua en la ciudad de Guadalajara así como la relación con sus principales fuentes de abastecimiento entre 1950 y 2005. Todo ello fue determinante para la transformación de la ciudad en gran metrópoli a partir de las políticas de desarrollo regional que se implementaron para el crecimiento de la ciudad a partir de los recursos hídricos con que contaba la región.El proceso histórico del abastecimiento de agua a la ciudad de Guadalajara, ahora Zona Metropolitana de Guadalajara (ZMG), se realizó a partir de la revisión de documentos históricos, bibliográficos y hemerográficos, y con investigación de campo, documentando cómo se forma la región hidrológica de Guadalajara y el modelo de gestión y distribución del agua en la ZMG, que ha impactado el medio ambiente, no sólo el de su área de influencia sino también el de toda la región, comprometiendo su futuro desarrollo.

Spectral Comparison of Real Spectra with Site Effects Included vs MOC-2008 Teorical Spectra for Guadalajara City, Mexico

Guadalajara city is the capital of the Mexican federal state of Jalisco. It is located close to the Pacific coast and is subjected to a large seismic risk. We present a seismic response study for some sites along the city. We calculated response spectra of shear-waves by using seismic records of actual earthquakes registered on rock and near the source as Green functions and propagated them trough a flat and horizontal layered media using a linear equivalent method to compare them with the response spectra calculated according to the Federal Commission of Electricity (CFE) seismic design buildings Manual (MOC-2008, 2008) which is widely used as reference on construction projects in Mexico. Our results show that MOC-2008 manual underestimates the spectral amplitudes and frequency band for the response spectra.

Digitalized Roads based on GPS Data in a Virtual World

In this paper an algorithm for implementing a digital map based on the path traveled by a vehicle manipulated in a Virtual World is presented. The algorithm sets the position of a virtual vehicle in a 3D coordinate system and determines the angle of direction to decide which parts of the road can be modeled as lines or curves. The least square method is employed to estimate the roads position based on the pattern of the route followed by the vehicle, with this purpose the equation of circle in curves and a polynomial equation in lines are employed. Two main steps are considered: the first one considers the VW creation using real GPS data and the second one simulates GPS data through a vehicle in the VW, such that, the analysis of GPS data simulated and the real data validates the proposed algorithm for building digitalized roads. The network of roads in the Virtual World simulate a suburb where is desired to implement a digital map, these roads are based on real GPS data of Guadalajara city. The proposed algorithm uses the data obtained with the virtual vehicle to estimate the position of the roads in the VW thatwas originally constructed with GPS data. It is verified that sampling the vehicle trajectory based only in the sampling time induce errors in the road estimation, then the position of the vehicle is sampled considering a minimum distance between samples.

ANÁLISIS IDEOLÓGICO DE LAS POLÍTICAS PÚBLICAS EN EL DEPORTE DESDE UN ENFOQUE PSICOSOCIOLÓGICO EN LA CULTURA FÍSICA. EL CASO DE GUADALAJARA, JALISCO, EN LA REPÚBLICA MEXICANA

Study based on literature review around the analysis of ideological discourse of public policy in the sport's field and the psychological aspects related to physical culture of two basic documents that describes the dominant ideology: State Law Sport oriented to competitive sport, elite sport and the youth population; and the "Via Recreactiva" in metropolitan area of Guadalajara city, which its supporters pretend to make a sense of idealism, hiding the socioeconomic interest that made possible its creation. Keywords: Psychology. Sport. Physical Culture. Public Policies.