Abstract Objective To estimate the projections of supply and demand for dialysis-nurses (DNs) over 5 years in 4 European countries (France, Italy, Spain, and United Kingdom). Methods This study modelled the nursing labour workforce across each jurisdiction, by estimating the current nursing labour force, number of nursing graduates and the attrition rate. Results France has currently the greater demand of DNs (51,325 patients on dialysis), followed by Italy, UK, and Spain with 40,661; 30,301; and 28,007 patients on dialysis, respectively. The number of in-centre haemodialysis patients (ICHD) is expected to increase in the four countries, while the number of patients on home-haemodialysis (HHD) or on peritoneal dialysis (PD) only is expected to increase in the UK. Currently Italy has the greater proportion of DNs (2.6%), followed by France (2.1%), Spain (1.7%), and United Kingdom (1.5%). The estimation of dialysis nursing staff growth rate over 5 years showed that the United Kingdom has the greater estimated growth rate (6%); followed by Italy (2%); France (2%), and Spain (1%). Conclusions Dialysis demand will increase in the coming years, which may exacerbate dialysis-nurse shortage. Additionally, competencies and training requirements of dialysis-nurses should be precisely defined. Finally, implementing and facilitating PD and HHD strategies would be helpful for patients, Health-care professionals, and Health care systems, and can even help ease the dialysis-nursing shortage.