Study Intervention Group Research Articles

The effect of training on reducing environmental stressors given to nurses on intensive care patients' perception of the presence of the nurse

Aim: The environmental characteristics of intensive care units include many stressors for patients. It is very important for nurses to recognize these stressors affecting the patient in intensive care units and develop solutions. In this way, patients’ exposure to stressors decreases and they feel cared by the nurse. The purpose of this study is to examine the effect of training on reducing environmental stressors given to nurses on intensive care patients' perception of the presence of the nurse. Material and Methods: The study is a quasi-experimental, separate sample group intervention study. The study was conducted in two groups: nurses working in the cardiovascular surgery intensive care unit and patients cared for by these nurses. The sample of the study consisted of 13 nurses working in the cardiovascular surgery intensive care unit and 66 patients, 33 before and 33 after the training. The nurses were given a 12-hour training to reduce environmental stressors in the intensive care environment. The study data were collected by interviewing the patients cared for by the nurses before and after the training. The ‘Patient Information Form’, ‘The Intensive Care Unit Environmental Stressors Scale’, ‘The Intensive Care Experience Scale’ and ‘The Nurse Presence Scale’ were used for the data collected from the patients. The data belonging to the nurses were obtained with the ‘Nurse Information Form’. SPSS 23.0 package program was used in the analysis of the data obtained in the study. Results: After the environmental stress factor reduction training provided to the nurses, an increase was observed in patients' perceptions of the nurse's presence and positive experiences in the intensive care unit, while no significant change was seen in the level of perception of environmental stress factors in the intensive care unit Conclusion: It was concluded that the 12-hour training given to intensive care nurses positively affected patients' perception of the presence of the nurse, was effective in patients' positive intensive care experiences and was more effective on physiopathologic stressors affecting patients.

Clinical evaluation of AYUSH-SL in patients receiving mass drug administration for the treatment of chronic inflammatory lymphedema, a double blind, placebo controlled, multicentric study.

A 2.5-year placebo controlled double blind trial was conducted to investigate the safety and efficacy of AYUSH- SL, a poly- herbal Ayurvedic formulation on filarial lymphedema in different endemic areas of India. Lymphatic filariasis (LF) is caused by parasitic nematodes from Wuchereria bancrofti, Brugia malayi, or B. timori that are transmitted through mosquitoes. In Ayurveda, LF has been elaborately narrated under the heading Shlipada, and the literature also includes detailed therapeutic measures. The multicenter, prospective, parallel group interventional study of a total of 180 participants were recruited within the duration through competitive enrollment. Diagnosed cases of grade I and grade II filarial lymphedema of Grade I and Grade II (lower extremities) were included in the trial. The study group was treated with MDA and AYUSH-SL or its placebo tablet. The control group had received MDA and a matching placebo. The primary outcome measure was the reduction in edema calculated for analysis by percentage reduction from baseline at the 4th, 12th and 24th week. Secondary outcome measures included improved quality of life (QoL), which was assessed using the Lymphatic Filariasis Specific QoL Questionnaire, and prevention of recurrence of acute episodes, which was evaluated by investigating the presence and severity of episodes in the past 4 weeks. The water displacement method for the evaluation of the efficacy of the intervention was shown to be highly significant compared to the baseline value (right leg; 3071.60 ± 970.482, 2828.40±829.339, p<0.001and Left leg; 3158.69 ± 1136.391, 2890.73 ±1077.475, p<0.001). There was significant improvement of Quality of Life in the LF QoL Questionnaire (p <0.001) at each follow-up visit in both groups. Safety estimations on hematologic and biochemical parameters were within limits and or changes were not significant. The results revealed that AYUSH- SL is safe and effective for FL due to its comprehensive anti-inflammatory, antimicrobial, and anti-allergic activities.

지역사회 고령자의 건강증진을 위한 그룹 중재 프로그램의 사회적 가치 측정 연구: 사회투자수익률 분석 활용

Objective: This study aimed to analyze the social benefits generated by community-based health promotion group interventions for older adults in comparison to their costs. Methods: Three community-based health promotion group intervention studies conducted in Wonju city were analyzed. Social Return on Investment (SROI) analysis was performed based on guidelines from previous studies. Results: The results showed that all group intervention programs for older adults generated high social value relative to their costs. Moreover, significant social value was created for participating researchers who designed and delivered the interventions. Conclusion: This study demonstrates the effectiveness of applying SROI methodology for developing and evaluating health promotion group intervention programs for older adults. Future research should focus on developing objective measures and indicators to evaluate the social value of interventions across occupational therapy, healthcare, and social welfare sectors.

Efficacy of modified electroconvulsive therapy as augmentation agent in treatment-resistant schizophrenia

AIM: The aim of the study was to study the efficacy of modified electroconvulsive therapy (MECT) as an augmentation agent in schizophrenia, with particular emphasis in treatment-resistant schizophrenia. MATERIAL AND METHODS: A prospective open-label, raters blinded within a group interventional study done over 1 year with 40 consenting adults with a diagnosis of treatment-resistant schizophrenia as per Conley and Kelly’s criteria. With preanesthetic clearance, they were put on a supervised regular MECT regimen after baseline clinical global impression (CGI), PANSS, and Brief Psychiatric Rating Scale (BPRS) application with improvement recorded by repeat application of psychopathology measurement scales. RESULTS: after a mean of 11.10 ± 1.6 MECT sessions ranging from 8 to 14, we observed an improvement of 30.6% ± 3.5% in total PANSS score with significant improvement in CGI and BPRS. CONCLUSION: The study endorses the efficacy of MECT augmentation in treatment-resistant schizophrenia.

Correspondence to "A preliminary study of collaborative group intervention with recovered peer supporters for eating disorders: Analyses including comparisons between in-person and online sessions".

Correspondence to "A preliminary study of collaborative group intervention with recovered peer supporters for eating disorders: Analyses including comparisons between in-person and online sessions".

Mixed methods on adverse childhood experiences predicting transitional and recurrent homelessness.

Research has associated lack of parental care, physical abuse, and parental substance abuse to homelessness, with the presence of two or more such factors dramatically increasing one's chances of becoming homeless as an adult. Less clear is which (cumulation of) factors may mediate the difference between transitional and recurrent homelessness. Quantitative analysis of four risk factors-addiction, weak social network, criminal activity, psychopathology-among 69 transitionally and recurrently homeless (RH) adults, followed by in-depth qualitative analysis of adverse childhood experiences (ACEs) among 30 selected participants. RH participants had higher cumulative risk and a higher prevalence and broader range of ACEs than transitionally homeless participants, with the prevalence of childhood physical abuse marking the greatest difference between the two groups. Recurrent homelessness was also correlated with addiction to hard drugs, criminal activity, and weak social networks. Longitudinal and intervention studies in larger groups are needed to assess causality.

The effect of the Watson model-based psycho-educational intervention on preventing postpartum depression.

Psycho-education application is effective in reducing the risk of postpartum depression (PPD) and increasing the level of social support. The quality of care increases with the implementation of Watson's Theory of Human Caring Model (WTHCM)-based care programs to reduce the risk of PPD. This study aimed to evaluate the impact of a psycho-educational intervention based on the Watson model on pregnant women in preventing PPD. Additionally, the effect of the psycho-educational intervention on women's perceptions of social support in relation to PPD was evaluated. A randomized-controlled pretest-posttest control group intervention study design was used. The sample consisted of 91 women (intervention:45, control:46) in their 20th to 32nd gestational week. While all women received routine care at the family health centre the intervention group was additionally applied a psycho-educational intervention based on the WTHCM. Chi-square and t-test analysis methods were performed to determine the homogeneity of the intervention and control groups. The t-test method was used to compare group scores. Multiple regression analysis was employed to compare multiple variables. Following the psycho-educational intervention, the total Edinburgh Postpartum Depression Scale of the intervention group was found significantly lower than that of the control group, but the total and friend subscale scores on the Multidimensional Scale of Perceived Social Support (MSPSS) were higher (p < 0.05). The regression analysis results indicate that friend and family support, which are sub-dimensions of the MSPSS, exhibited a significant decrease in both groups. Furthermore, this decline had a greater impact on reducing the PPD level in the intervention group compared to the control group. It was found that while the support of the significant other sub-dimension reduced the PPD level in the intervention group, it did not make a significant difference in the control group. The Watson's Theory of Human Caring Model-based psycho-educational intervention program decreased women's risk of PPD and increased their social support levels. It is recommended to use approaches that include psycho-educational intervention in postpartum midwifery care.

A preliminary study of collaborative group intervention with recovered peer supporters for eating disorders: Analyses including comparisons between in‐person and online sessions

AbstractAimsThis study aimed to evaluate the impacts of a single‐session group intervention for individuals with an eating disorder that involved collaborations between peer supporters, who had recovered from an eating disorder, and psychological professionals. We also compared intervention effects between in‐person and online settings.MethodsParticipants with an eating disorder were recruited through online platforms and public promotional materials. The inclusion criteria involved individuals who had current eating disorders and were willing to openly share their experiences during the session in which the Reflecting Team method was applied.ResultsThe analysis included 103 participants (75 in‐person and 28 online). We found significant time‐based effects (F(1, 101) = 70.390, p &lt; 0.001, ηG2 = 0.083), which indicated that participants experienced reductions in feelings of isolation, hopelessness associated with their eating disorder, and belief in the incurability of their disorder following the group interventions. No significant differences were observed between in‐person or remote sessions (F(1, 101) = 0.087, p = 0.768, ηG2 = 0.001).ConclusionsOur findings suggest that peer supporters serve as a source of hope for individuals with eating disorders, even within group settings. Furthermore, the similar outcomes across in‐person and online sessions show the promise of remote group sessions as a novel means of support for individuals with eating disorders, regardless of their geographical location. However, future randomized controlled trials of continuous group therapy sessions are essential to confirm their effectiveness.

Increasing perceived health and mental health literacy among separated refugee Ukrainian families with urgent needs occasioned by invasion-a group intervention study with participatory methodology in Sweden.

With the increasing numbers of refugees from Ukraine affected by the ongoing war, there is a high risk of trauma-related stress due to low local health and mental health literacy care. Perceived good health is a human right. Earlier studies show that intervention for refugees can reduce and prevent post-migration stress and anxiety. The present explorative study aimed to investigate the feasibility and effectiveness of a short, trauma-focused group intervention (in Swedish "hälsoskola") for Ukrainian-speaking refugees (EU's mass refugee directive). This intervention was part of an ESF project aiming to get the subjects closer to the labor market in Västernorrland County, Sweden. A mixed-methods design, a participatory methodology, and an evaluation were used. Data were obtained with a short questionnaire in Ukrainian. It included a visual analogue health-rating scale, an observation, and an oral evaluation in groups. For practical and ethical reasons, there was no control group. Each group met five times for 2 h, a total of 10 h excluding pre- and post-assessment. There were eight sets of five group sessions per set, a total of 40 sessions. Brief initial and concluding breathing exercises sought to reduce stress among the participants. Baseline data were obtained from 99 participants, mostly females. Data gathered directly after the group intervention from 57 participants who had filled in both the pre- and post-questionnaires showed that (1) perceived anxiety/stress was significantly reduced (chi-2 25,53, df = 4, p < 001). (2) The participants showed significantly better perceived health as assessed on a visual analogue scale (average change from 63.16 to 71.18, p < 0.001). This result was supported by the participants' questions, which were qualitatively evaluated using thematic content analysis. Five general themes stemmed from questions raised in dialogue with the participants plus observation with the respective local expert. The participants received answers to their questions, and their perceived negative attitudes to authorities changed to more positive ones. By dialogue between the participants' needs of knowledge and direct answers by the local expert, respectively, was feasible and effective as they perceived trust and health and mental health literacy increased. Implications for primary prevention are discussed.

Cost-effectiveness and cost-utility study of a psychoeducational group intervention for people with depression and physical comorbidity in primary care

ObjectiveTo evaluate the cost-effectiveness and cost-utility of a psychoeducational group intervention led by primary care (PC) nurses in relation to customary care to prevent the depression and improve quality of life in patients with physical comorbidity. DesignEconomic evaluation based on data from randomized, multicenter clinical trial with blind response variables and a one-year follow-up, carried in the context of the PSICODEP study. Location7 PC teams from Catalonia. Participants>50 year-old patients with depression and some physical comorbidity: diabetes mellitus type 2, ischemic heart disease, chronic obstructive pulmonary disease, and/or asthma. Intervention12 psychoeducational group sessions, 1 per week, led by 2 PC nurses with prior training. MeasurementsEffectiveness: depression-free days (DFD) calculated from the BDI-II and quality-adjusted life years (QALYs) from the Euroqol-5D. Direct costs: PC visits, mental health, emergencies and hospitalizations, drugs. Indirect costs: days of temporary disability (TD). The incremental cost-effectiveness ratios (ICER), cost-effectiveness (ΔCost/ΔDLD) and cost-utility (ΔCost/ΔQALY) were estimated. ResultsThe study includes 380 patients (intervention group [IG] = 204; control group [CG] = 176). 81.6% women; mean age 68.4 (SD = 8.8). The IG had a higher mean cost of visits, less of hospitalizations and less TD than the CG. The difference in costs between the IG and the CG was −357.95€ (95% CI: −2026.96 to 1311.06) at one year of follow-up. There was a mean of 11.95 (95% CI: −15.98 to 39.88) more DFD in the IG than in the CG. QALYs were similar (difference −0.01, 95% CI −0.04 to 0.05). The ICERs were 29.95€/DLD and 35,795€/QALY. ConclusionsPsychoeducational intervention is associated with an improvement in DFD, as well as a reduction in costs at 12 months, although not significantly. QALYs were very similar between groups.

Focusing with colorectal cancer patients: a pilot study of a brief online group intervention.

Focusing-Oriented Psychotherapy has had a long history and influence on the field of psychotherapy. By "clearing a space" and "focusing," individuals can enhance their emotional awareness and improve their ability to self-regulate. These tasks are particularly relevant in the context of Psycho-Oncology, although the research on their potential benefits for cancer patients is limited. Furthermore, the application of these tasks in a group or online setting has not been thoroughly explored. This study aimed to examine the effectiveness of a two-session online intervention based on Focusing for cancer-diagnosed participants and its impact on their mental health and wellbeing. The study involved three participants with a diagnosis of colorectal cancer who were undergoing palliative treatment. We used both qualitative and quantitative methods. PFC-2 was used to assess participants' accomplishment of the task; FMS was used to assess the change in the focusing attitude, while CORE-OM, and PWBS-RV were used as mental health distress and psychological wellbeing measures; participant feedback was collected through questionnaires and a semi-structured interview. The results suggest that the tasks led to greater self-awareness, heightened self-reflection, and a sense of relief for the participants. These findings suggest that the group intervention protocol based on online Focusing sessions is potentially useful for broader applications.

'I became more aware of my actions'-A qualitative longitudinal study of a health psychological group intervention for patients with myalgic encephalomyelitis/chronic fatigue syndrome.

To explore myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) patients' experiences of a health psychological group intervention and its usefulness, non-usefulness or harmfulness for illness management and adjustment. A qualitative longitudinal study using inductive content analysis. Semistructured interviews were conducted with 10 adults. Interviews were conducted before the 16-week intervention, immediately after its completion, and at 3 months after completion. Participants reported that the intervention was useful and not harmful. The model improved their ability to cope with ME/CFS by providing them with useful information about the illness along with peer support and professional guidance. Participants reported improved illness management and adjustment, which they perceived as an outcome of achieving new ways of thinking, feeling and acting. Participants viewed the health psychological approach to group intervention as meeting their needs. To achieve better illness management and adjustment, more consideration should be given to supportive interactional processes with peers and healthcare professionals. The intervention was developed to meet patients' needs of finding ways to manage their illness. The research team consulted eight patients with ME/CFS and three clinical centres working with ME/CFS treatment and rehabilitation at the intervention planning stage. Their comments influenced the planning and content of the intervention as well as ethical issues that should be considered, such as potential harm to participants. All participants were informed about the theoretical foundations of the study and the principles guiding the intervention. Participants were not involved in the data analysis. NCT04151693.

Smoking Cessation Interventions for Chinese American Smokers: A Systematic Review and Meta-Analysis.

Smoking cessation interventions are important for decreasing lung cancer mortality rate among Chinese Americans. This study aims to investigate and summarize the intervention methods focusing on smoking cessation among Chinese Americans and to compare the effects of intervention methods on the smoking cessation rates. A systematic review and meta-analysis design was used in this study. Keyword searching was conducted in August 2021 on PubMed, Google Scholar, PsycINFO, and CINAHL. The methodological quality of each study was assessed using the PEDro scale or The Methodological item for non-randomized studies (MINORS). The Review Manager Version 5.4 software was used to conduct the meta-analysis. Random effect model and subgroup analysis were applied in the analysis. Twenty and 11 studies were included in the systematic review and meta-analysis, respectively. Of the 20 studies, 8 were randomized control studies, 9 were pre-post single group intervention studies, 1 was retrospective analysis for an intervention study, 1 was a baseline data analysis from a cluster randomized trial, 1 was a feasibility intervention study. Results showed that compared to the control group, the group that received interventions on smoking cessation had a significantly increased smoking cessation rate (OR, 3.76; 95% CI, 1.72-8.21; P=0.0009). Subgroup analysis showed individual-based (OR, 5.88) NRT outreach interventions (OR, 3.80) conducted in person (OR, 2.53) with smokers (OR, 6.64) seemed to be more effective to increase smoking cessation rates among Chinese Americans compared with group-based, telephone counseling, indirect remote interventions conducted among Chinese American smokers and their non-smoke family members. Individual-based NRT outreach interventions conducted in person with smokers is an effective way to increase smoking cessation rates among Chinese Americans. More culturally sensitive and effective interventions are needed to help Chinese American smokers to quit smoking.

The Impacts of Supervised Exercise Intervention on Tobacco Withdrawal Symptoms.

This study examined a supervised moderate-intensity aerobic exercise programme's effectiveness in regulating the Tobacco Withdrawal Symptoms (TWS) during temporary abstinence. This was a single group, pre and post-quasi intervention study. Thirty daily smokers participated in an 8-week supervised moderate-intensity aerobic exercise programme. We assessed the TWS, smoking urge, mood and stress-pleasure related hormonal variables after the aerobic exercise intervention. The measurements were conducted after overnight abstinence at baseline, post-intervention (at week-8) and post-detraining (at week-10). TWS components, smoking urge and mood were found to improve. For hormonal variables, cortisol and beta-endorphin except adrenaline showed insignificant changes at post-intervention and de-training. The findings suggest moderate-intensity exercise might help in reducing withdrawal symptoms and its adverse effects. Thus, exercise is an effective adjunct treatment in a smoking cessation programme.

Hemşirelik Öğrencilerine Verilen Duygu Yönetimi Eğitiminin Aleksitimi ve Öz Bilinç Düzeyine Etkisi: Randomize Kontrollü Bir Çalışma

Aim: This study was conducted to evaluate the effect of emotion management training given to nursing students on alexithymia and self-consciousness levels. Methods: This research, is control group intervention study. The sample of the study was determined by power analysis and 32 students were assigned to the intervention group and 32 students to the control group by simple random sampling method. The data were collected between February-June 2021. In the collecting data were used Socio-demographic Data Form, Toronto Alexithymia Scale and Self- Consciousness Scale. In the analysing of data were used t test for dependent groups, t test for independent groups, chi-square and ANOVA tests. Findings: In the intervention group of students’ Toronto Alexithymia Scale mean score pre-test are 67.03±10.86, post-test 49.75±8.25; in the control group of students pre-test are 69.03±8.23, post-test 69.87±10.15, and it was determined that the difference between the post-test mean scores of the groups was statistically significant (p&lt;0.05). In the intervention group of students’ Self-Consciousness Scale mean score pre-test are 31.59±6.75, post-test 38.84±3.41; in the control group of students pre-test are 32.46±6.97, post-test 32.21±7.36, and it was determined that the difference between the post-test mean scores of the groups was statistically significant (p&lt;0.05). Result: It was determined that given to students emotional management training were affected positive way alexithymia and self-consciousness levels.

The effect of web based type 2 diabetes education on diabetes self management.

This study is a control group intervention study to determine the effect of web-based education on diabetes self-management in individuals with type 2 diabetes. The study was conducted in the Training and Research Hospital Diabetes Education Unit of Hitit University. The study was completed with 75 people (intervention 38, control 37). The data were obtained in the web site through patient identification form, self-management perception scale in diabetes, diabetes attitude, self-care scale and HbA1c, HDL, LDL values were followed by providing training and counseling. The values followed were viewed at the third and sixth months. Written permission was obtained from ethics committee and participants. The data of the study were evaluated with number, percentage, mean, pearson chi-square, independent t-test, repetitive analysis and variance analysis. Statistically significant decrease in HbA1c and LDL values, diabetes self-management scale, diabetes attitude scale and self-care scale scores were found to be significantly different between the intervention and control groups. Web-based education and follow-up studies are effective in decreasing HbA1c values in increasing diabetes self-management skills of individuals with type 2 diabetes. It is recommended to use as a complementary tool in health care services for type 2 diabetes management.

Systematic development and feasibility testing of a multibehavioural digital prehabilitation intervention for patients approaching major surgery (iPREPWELL): A study protocol.

Improving outcomes for people undergoing major surgery, specifically reducing perioperative morbidity and mortality remains a global health challenge. Prehabilitation involves the active preparation of patients prior to surgery, including support to tackle risk behaviours that mediate and undermine physical and mental health and wellbeing. The majority of prehabilitation interventions are delivered in person, however many patients express a preference for remotely-delivered interventions that provide them with tailored support and the flexibility. Digital prehabilitation interventions offer scalability and have the potential to benefit perioperative healthcare systems, however there is a lack of robustly developed and evaluated digital programmes for use in routine clinical care. We aim to systematically develop and test the feasibility of an evidence and theory-informed multibehavioural digital prehabilitation intervention 'iPREPWELL' designed to prepare patients for major surgery. The intervention will be developed with reference to the Behaviour Change Wheel, COM-B model, and the Theoretical Domains Framework. Codesign methodology will be used to develop a patient intervention and accompanying training intervention for healthcare professionals. Training will be designed to enable healthcare professionals to promote, support and facilitate delivery of the intervention as part of routine clinical care. Patients preparing for major surgery and healthcare professionals involved with their clinical care from two UK National Health Service centres will be recruited to stage 1 (systematic development) and stage 2 (feasibility testing of the intervention). Participants recruited at stage 1 will be asked to complete a COM-B questionnaire and to take part in a qualitative interview study and co-design workshops. Participants recruited at stage 2 (up to twenty healthcare professionals and forty participants) will be asked to take part in a single group intervention study where the primary outcomes will include feasibility, acceptability, and fidelity of intervention delivery, receipt, and enactment. Healthcare professionals will be trained to promote and support use of the intervention by patients, and the training intervention will be evaluated qualitatively and quantitatively. The multifaceted and systematically developed intervention will be the first of its kind and will provide a foundation for further refinement prior to formal efficacy testing.

The Emotional Resources Group: A Mixed Methods Practice-Based Study of a Transdiagnostic Emotion Regulation Group Intervention

Objectives: This study aimed to understand if the emotional resource group (ERG), a transdiagnostic group intervention, significantly improved emotion regulation (ER) in the short and long term. Methods: Participants completed pre- and post-measures of emotional regulation, psychological distress, wellbeing, self-efficacy and confidence in managing mental health problems. Measures were repeated at three and six months post intervention. 14 participants completed a qualitative interview. Results: ER ability and secondary measures improved following the intervention, but the improvement was not maintained over the three and six month follow-up period. From the themes identified through thematic analysis, the ERG was part of a wider process of learning and change for most participants. Participants described changes in awareness, and implementation of new skills to manage their emotional difficulties. Conclusion: Overall the ERG was a positive experience for most participants, providing improvements in ER and other aspects of mental health. However, it is unclear if these improvements are sustained in the longer term. There may be many reasons for this, including fidelity to the ERG model and the short-term nature of the group. The ERG should be considered an option for participants with ER difficulties and further intervention should be offered when the ERG ends.

An evaluation of intervention research for transition-age autistic youth.

In this study, we assess the quality of intervention research that focuses on autistic youth who are 14-22 years old. We found 193 different studies on this topic, and carefully reviewed them. Most of these studies tested strategies that were behavioral. This means that they used procedures like prompting and rewards to change participants' behavior. We found that the majority of studies had problems that make it hard to determine whether or not the intervention worked. The problems related to how researchers designed their studies, and how they measured the study outcomes. We also found that researchers rarely tried to find out if the strategies they studied had unintended negative effects for participants. Because of these issues, we make suggestions for how researchers might design better studies that will let people know how well the strategies worked.

Effect of Ayurvedic Intervention as an adjunct therapy in Post COVID-19 Mucormycosis (PCM): A non-randomized parallel group study

BackgroundThe Ayurveda therapy is often used as an adjunct to conventional allopathic treatments for management of chronic disorders including life threatening infections such as post COVID-19 Mucormycosis (PCM). Aims/objectivesThe aim of the current study is to evaluate the role of adjunct Ayurveda therapy (AAT + CAT) over conventional Allopathic therapy (CAT) in the prevention of progression of oral/orbital/neural extension of PCM. Material and methodsA non-randomised parallel group interventional study was on a sample of 92 cases of PCM, sorted into two groups i.e. group A (n = 46; AAT + CAT) and group B (n = 46; CAT/controls). The group A received AAT (lab-tested standardised regimen) while simultaneously receiving conventional antifungal measures (or CAT). The outcomes assessed were clinical symptomatic grading score, Nasal endoscopic examination for patency of sinuses, Progression or extension of disease from sinuses to maxilla, orbit and brain, need of additional surgical interventions and antifungal medication after study period, adverse drug reactions and mortality. ResultsThe group A (AAT + CAT)) had shown extension free PCM in 86.96% (n = 40) as opposed to 41.3% (n = 19) in group B (CAT), No surgical interventions were needed in 89.13% (n = 41) in group A vs. 60.87% (n = 28) in group B. Around 69.5% (n = 32) in group A vs. 4.37% (n = 2) in group B did not need antifungal medication. The safety of both arms of the therapy has been determined by liver function and renal profile which are with in normal range in both groups. ConclusionAdjunct Ayurveda therapy (given along with routine medical therapy) for PCM showed a better cure and reduced disease progression after a trial period of 45 days and in the extended observational period of three months. AAT + CAT regimen is not only therapeutically effective, but also safe and economical option to consider for PCM.