Greater Increase Research Articles

Das Jüdisch-Mittelalterliche Erbe in Erfurt auf der Welterbeliste

Abstract On September 17, 2023, the Jewish Medieval Heritage in Erfurt was inscribed on the UNESCO World Heritage List at the 45th session of the World Heritage Committee chaired by Saudi Arabia in Riyadh. This brought a decades-long process to its provisional conclusion, in which research into the history of the Jewish community in Erfurt in the Middle Ages and its material evidence had been intensified in preparation for the World Heritage application and also during the evaluation, thus leading to a great increase in knowledge. This process should and must continue, but an (interim) conclusion can be drawn in this paper.

The Southern African Heat Low: Structure, Seasonal and Diurnal Variability, and Climatological Trends

Abstract Heat lows are key features of subtropical climates and monsoon systems. In southern Africa, they are pivotal to understanding divergent climate change projections, in particular the veracity of future rainfall decline. Compared to other heat lows, including in West Africa and Australia, the southern African heat low remains poorly documented. Here, we analyze the diurnal cycle, seasonal variability, and trends of the heat low in reanalysis data. In ERA5, 462 strong heat low days are detected between September and March from 1990 to 2019, equating to 7.3% of days sampled. These events feature ascent (exceeding −0.2 Pa s−1) at low levels (strongest between 800 and 600 hPa) and subsidence aloft, generating low-level cyclonic flow with anticyclonic flow above. This flow exhibits strong diurnal variability, with peak windspeeds between 0600 and 0900 UTC and maximum ascent at ∼2300 UTC. Heat lows form preferentially over Angola in September (∼14°S) and October (15°–20°S), and in Namibia from November to March (∼20°–26°S). Strongest ascent occurs over areas of high elevation. Finally, we show a rapidly increasing frequency of strong heat low days, with a 175% increase between 1960–89 and 1990–2019. The greatest increase (459%) has occurred in the early summer months of September and October, consistent with projections of delayed rainfall onset. Strikingly, more strong heat lows are detected in the most recent 5 years of analysis (2014–19) than in the 30-yr period from 1960 to 1989. These results suggest the heat low is an important feature in determining drying trends over southern Africa and is a vital indicator of climate model accuracy. Significance Statement This work documents the heat low that forms in southern Africa in the lowest levels of the atmosphere. The feature is present during austral summer (from September to March) and is associated with below average rainfall across much of the subcontinent. The frequency of strong heat lows has rapidly increased in line with regional amplified warming trends. The heat low is identified as an important control on circulation and precipitation patterns and changes in the frequency or intensity of the feature in the future are likely to influence the strength of declining rainfall trends across southern Africa.

Spectrum-efficient user grouping and resource allocation based on deep reinforcement learning for mmWave massive MIMO-NOMA systems

Millimeter-wave (mmWave) massive multiple-input multiple-output non-orthogonal multiple access (MIMO-NOMA) is proven to be a primary technique for sixth-generation (6G) wireless communication networks. However, the great increase in users and antennas brings challenges for interference suppression and resource allocation for mmWave massive MIMO-NOMA systems. This study proposes a spectrum-efficient and fast convergence deep reinforcement learning (DRL)-based resource allocation framework to optimize user grouping and allocation of subchannel and power. First, an enhanced K-means grouping algorithm is proposed to reduce the multi-user interference and accelerate the convergence. Then, a dueling deep Q-network (DQN) structure is proposed to perform subchannel allocation, which further improves the convergence speed. Moreover, a deep deterministic policy gradient (DDPG)-based power resource allocation algorithm is designed to avoid the performance loss caused by power quantization and improve the system’s achievable sum-rate. The simulation results demonstrate that our proposed scheme outperforms other neural network-based algorithms in terms of convergence performance, and can achieve higher system capacity compared with the greedy algorithm, the random algorithm, the RNN algorithm, and the DoubleDQN algorithm.

Atmospheric and Oceanic Factors Related to the Increasing Summer High Temperature Extremes on the Tibetan Plateau under the Background of Global Warming

Abstract The related atmospheric and oceanic factors are investigated in this analysis to understand the natural attributes responsible for the significant increase of the high temperature extremes (HTEs) on the Tibetan Plateau (TP) in summer. It is found that a stronger-than-normal South Asian high (SAH) and corresponding weaker-than-normal East Asian jet, an anomalous anticyclone and intensified midlevel westerly wind over the TP, and a more extensive, stronger, farther westward- and northward-stretching western Pacific subtropical high motivate more occurrences of HTEs over the TP on the interannual time scale. From 1961 to 2021, these crucial circulation patterns show a significant changing trend favorable for the occurrence of HTEs and thus contribute to its great increase. Further, the significant warmings of sea surface temperature (SST) in the tropical western Indian, northern North Pacific, and western North Atlantic Oceans make great contributions through different air–sea interactive processes as the Matsuno–Gill response, zonal vertical circulation cell, and mid- to high-latitude teleconnection wave train, respectively. Meanwhile, the interdecadal variability plays an important role. A breakpoint at the early twenty-first century is detected in the occurrence of summer HTEs on the TP. Both the crucial circulation patterns and the SST anomalies in the key oceanic regions experienced significant interdecadal transition to favor the occurrence of HTEs. In particular, the Atlantic multidecadal oscillation (AMO) is significantly and positively correlated with the interdecadal variation of summer HTEs on the TP. The zonal teleconnection wave train triggered by AMO forms a stronger-than-normal SAH and strengthened midlevel westerly airflow over the TP, conducive to the increase of summer HTEs on the TP.

1239 Trends in Geospatial Availability of Neuro-oncology Clinical Trials in the United States Over Two Decades

INTRODUCTION: Advances in brain tumors treatments rely on successful neuro-oncology (NO) clinical trials. To date, data on NO trials completion in the US is scarce. Understanding these factors could help improve access to and the design of future clinical trials. METHODS: NO clinical trials registered in the US were analyzed (2000-2019). Univariate and multivariate analysis were used to compare success rates among trials. Geospatial analysis was performed to determine the trial density and failure rates across different states. Trial density was estimated by the number of trials/state population. RESULTS: A total of 2,610 neuro-oncology clinical trials were registered in the US during the study period, of which 1,257 met a primary endpoint – completion or trial failure. North Dakota had the highest trial density (6.03 trials/100,000 residents), followed by South Dakota (5.83) and several Northeastern states (3.90-5.60). The change in trial failure rates did not correlate with trial density by state (p = 0.777). The states with the greatest increase in trial failure rates were Nevada (23.1%), West Virginia, Alaska, and Idaho (all three at 20.0%). Florida showed a trend towards a statistically significant increase in failure rates to 10.9% (p = 0.09). CONCLUSIONS: The results of this study highlight the variations in success rates and geographic distribution of neuro-oncology clinical trials in the United States. Factors beyond trial density may be critical to trial success. The significant geographic variations in trial density and failure rates across states emphasize the need for targeted efforts to improve access participation to trials in certain regions. Further studies aimed at identifying the factors contributing to the increase in trial failure rates are needed to develop strategies to improve trial enrollment.

An insight into the interfacial structure and mechanical properties of Al/Cu laminate fabricated through cold spraying and post-treatment

The Al/Cu laminate was fabricated using cold spraying, and post-treatments of annealing and hot compression were conducted to enhance the mechanical properties of the laminate. The interfacial structure, microstructure, and mechanical properties were investigated. It was observed that cold spraying resulted in a mechanical bonding at the Al/Cu interface, and some pores, cracks, and other defects were present. During annealing treatment, intermetallic compounds (IMCs) such as CuAl2, Cu9Al4, and CuAl formed, and the thickness of IMCs increased with increasing temperature. The hot compression enhanced the density of the cold sprayed Cu layer and induced a large number of dislocations at Al and Cu layer, causing a great increase in tensile strength of the laminate. A good combination of tensile strength and elongation was achieved by performing both hot compression and annealing. Additionally, the microcracks generated by internal stress tended to form and propagate in the IMCs layer. IMCs can fill the pores at the interface, thereby increasing the interlayer bonding strength. However, when the thickness of IMCs reached a certain value, the bonding strength declined due to their brittle feature.

High‐frequency resistance training improves maximal lower‐limb strength more than low frequency

AbstractThis study compared the effects of a weekly lower body resistance‐training program divided into low frequency (LOW, one long session) versus high frequency (HIGH, four shorter sessions) in resistance‐trained individuals. Twenty‐two adults with more than 6 months resistance training experience were randomized to either the LOW or HIGH intervention group. Both groups completed an 8‐week training program consisting of four multi‐joint exercises targeting the hip and knee extensors. The program progressed from 12‐repetition maximum (RM) to 6‐RM, with 4–5 sets per exercise performed throughout the intervention. The four exercises were conducted either in one session or four sessions (one exercise per session) per week. 1‐RM in the squat, muscle thickness of the vastus lateralis, muscle mass of the lower body (measured using bioelectrical impedance), and jump height were assessed pre‐ and post‐intervention. The HIGH group demonstrated a statistically significant increase in 1‐RM compared to the LOW group (7 kg, p = 0.01), while no statistically significant differences were found between the groups for the other outcomes (p = 0.26–0.63). Both interventions resulted in statistically significant increases in 1‐RM squat (8 and 15 kg), muscle thickness (2.3 and 2.8 mm), and jump height (1.5 and 1.9 cm) from pre‐to post‐test. There were no statistical changes in lower‐body muscle mass for either group (p = 0.16–0.86). In conclusion, a weekly training protocol of four multi‐joint lower‐limb exercises distributed over four sessions resulted in greater increases in maximal strength compared to one session in resistance‐trained adults. Both frequencies were similarly effective in improving muscle hypertrophy and jump height.

Leukocytes and lactate responses to cycling and running at the same target heart rate

AbstractHeart Rate (HR) is widely used for erobic exercise intensity prescriptions and/or studies of exercise training. It is often assumed that exercising at a given HR results in similar physiological response, regardless of exercise modality. This study aimed to gauge cellular immune mobilization to submaximal exercise at a given target HR on a cycle ergometer (CE) and treadmill (TM). Thirteen healthy male adults (23.2 ± 3.5 y.o) completed 4 laboratory visits. Participants performed two graded exercise tests to exhaustion on CE and TM and two 30‐min constant exercise challenges at 70% HR reserve on CE or TM in random order. Rating of Perceived Exertion (RPE) was recorded every 5 min, and blood was drawn before and after exercise to measure leukocytes subpopulation levels, lactate, and IL‐6. HR was successfully “clamped” during the exercise in CE and TM (CE 156.7 ± 1.1; TM 159.3 ± 1.6 bpm). Cycling was perceived as more strenuous than running and was accompanied by a greater increase in lactate post‐exercise (p < 0.0001; 6.2 ± 0.3 vs. 2.9 ± 0.3 mmol/L). IL‐6 and leukocytes subpopulations were significantly elevated post‐exercise (p < 0.003) with no difference between exercise modalities (monocytes; CE 57.6% TM 61.2%, granulocytes; CE 41.37%, TM 50.1%, lymphocytes; CE 91.03%, TM 78.8%). The findings revealed that HR is not sufficient in and of itself to fully assess the metabolic stress associated with a given exercise modality. However, despite different metabolic and subjective stress, the IL‐6 and leukocyte counts relative changes were similar in the two modalities.

Market Manipulation of Cryptocurrencies: Evidence from Social Media and Transaction Data

The cryptocurrency market cap has experienced a great increase in recent years. However, large price fluctuations demonstrate the need for governance structures and identify whether there are market manipulations. In this article, we conduct three analyses—social media data analysis, blockchain data analysis, and price bubble analysis—to investigate whether market manipulation exists on Bitcoin, Ethereum, and Dogecoin platforms. Social media data analysis aims to find the reasons for price fluctuations. Blockchain data analysis is used to find detailed behavior of the manipulators. Price bubble analysis is used to investigate the relation between price fluctuation and manipulators’ behavior. By using the three analyses, we show that market manipulation exists on Bitcoin, Ethereum, and Dogecoin. However, market manipulation of Bitcoin is limited, and for most of Bitcoin’s price fluctuations, we found other explanations. The price for Ethereum is the most sensitive to technical updates. Technical companies/teams usually hype some new concepts (e.g., ICO, DeFi), which causes a price spike. The price of Dogecoin has a high correlation with Elon Musk’s X (formerly known as Twitter) activity, showing that influential individuals have the ability to manipulate its prices. In addition, the poor monetary liquidity of Dogecoin allows some users to manipulate its price.

Effects of different fertilization practices on maize yield, soil nutrients, soil moisture, and water use efficiency in northern China based on a meta-analysis

The application of fertilizer to ensure the steady improvement of crop yield has become the main means of agricultural production. However, it remains to be determined whether fertilization practices with different combinations of nitrogen (N), phosphorus (P), potassium (K), and organic (O) fertilizers play a positive role in the sustainability of maize yield and the soil in which it is grown. Therefore,this meta-analysis extracted 2663 data points from 76 studies to systematically analyze and explore the effects of different fertilization measures on maize yield, soil nutrients, water content and water use efficiency (WUE) in northern China. Articles addressing this topic showed that fertilization effectively increased the soil nutrient content and maize yield. The soil organic matter (SOM) increased by 2.36 (N)–55.38% (NPO), total nitrogen content increased by 6.10 (N)–56.39% (NPO), available phosphorus content increased by 17.12 (N)–474.74% (NPO), and available potassium content changed by − 2.90 (NP)–64.40% (NPO). Soil moisture increased by 3.59% under a single organic fertilizer application and decreased by 4.27–13.40% under the other treatments. Compared with no fertilization, the yield increase of fertilized maize reached 11.65–220.42%. NP, NPK and NPKO contributed the most to increased yield in lithological, black and fluvo-aquic soils, respectively. The effects of different fertilization practices on maize yield varied in response to the same meteorological factors. The WUE increased from 9.51 to 160.72%. In conclusion, rational fertilization can improve the soil nutrient content and increase maize yield. The combined application of chemical and organic fertilizer showed the greatest increase in yield and WUE. Organic fertilizer application alone increased soil moisture. Our results provide a theoretical basis for fertilizer application and for improving the soil structure for maize cultivation in northern China.

Effects of transcutaneous auricular vagus nerve stimulation at left cymba concha on experimental pain as assessed with the nociceptive withdrawal reflex, and correlation with parasympathetic activity.

The aim of this study was to clarify the effects of transcutaneous auricular vagus nerve stimulation (taVNS) to the left cymba concha on the pain perception using nociceptive withdrawal reflex (NWR), which is known to be associated with chronic pain, and to investigate whether there is a relationship between taVNS-induced suppression of the NWR and parasympathetic activation. We applied either 3.0mA, 100 Hz taVNS for 120 s on the left cymba concha (taVNS condition) or the left earlobe (Sham condition) for 20 healthy adults. NWR threshold was measured before (Baseline), immediately after (Post 0), 10min (Post 10) and 30 min after (Post 30) stimulation. The NWR threshold was obtained from biceps femoris muscle by applying electrical stimulation to the sural nerve. During taVNS, electrocardiogram was recorded, and changes in autonomic nervous activity measured by heart rate variability (HRV) were analyzed. We found that the NWR thresholds at Post 10 and Post 30 increased compared with baseline in the taVNS group (10min after: p = .008, 30 min after: p = .008). In addition, increased parasympathetic activity by taVNS correlated with a greater increase in NWR threshold at Post 10 and Post 30 (Post 10: p = .003; Post 30: p = .001). The present results of this single-blinded study demonstrate the pain-suppressing effect of taVNS on NWR threshold and suggest that the degree of parasympathetic activation during taVNS may predict the pain-suppressing effect of taVNS after its application.

Modeling the line contact on an elastic half-space with the statistical approach: Self-affine fractal roughness and numerical framework

This paper presents a line contact model for describing the normal contact between rough surfaces with self-affine fractal roughness based on the statistical approach. An iterative algorithm combining the Levenberg-Marquardt (LM) method with penalty function is proposed to overcome the limitation of restricted indentation depth. Results show a competitive relationship between the plasticity index and the fractal dimension on the real contact area. Besides, nonlinear characteristics between force and area appear when the elastic modulus of the substrate is larger than that of the asperity. Furthermore, the wavy machining texture leads to a great increase in the maximum pressure. The current work can be used for modeling the transmission interfaces involving line contact, such as gears and cylindrical rotor bearings.

Dodine an effective alternative to copper for controlling Venturia oleaginea, the causal agent of pea-cock eye disease, in highly infected olive trees.

A trial was carried out in central Italy in an olive orchard of cultivar Moraiolo, highly infected by Venturia oleaginea. The aim of the investigation was to evaluate the effects of autumn and spring applications of copper oxychloride or dodine to control the disease. Non treated trees were used as the control. The effects of the fungal attacks on leaves and inflorescence development confirmed the high susceptibility of the cultivar Moraiolo to the disease. The results show that in trees heavily infected, but with most of the infected leaves at the early stage of the disease (asymptomatic phase), treatments with dodine had a curative effect, with consequent reduction in the appearance of symptomatic leaves and defoliation with respect to the control or copper-treated trees. The use of dodine against the autumnal attacks of V. oleaginea allowed most of the old leaves to be maintained until the new ones had formed, which is important for the growth processes during the early part of the growing season. Overall, the results indicate that to efficiently control the pathogen using copper compounds, treatments must start soon after the beginning of the attack and be repeated in order to maintain the infection at a low level. Dodine can be efficiently used if there is a great increase in infected leaves. The use of dodine to solve particular situations and not for normal repeated use is regulated by the fact that in some countries, Italy included, protocols for integrated pest management allow only one dodine treatment/year.

Relationship Between Social Support and Clinical Outcomes: An Evaluation of Participant-Nominated Treatment Supporters in the HOPE 4 Intervention.

The HOPE 4 trial (Heart Outcomes Prevention and Evaluation 4) investigated the effectiveness of a comprehensive, collaborative model of care, implemented in Colombia and Malaysia, which aimed to reduce cardiovascular disease risk in individuals with hypertension. One component of this intervention was the nomination of a treatment supporter, where participants could select a family member or friend to assist them with their care. The purpose of this study was to investigate the impact of these individuals on participant outcomes, as well as the relationship dynamics between participants and their treatment supporter. Participants in the HOPE 4 intervention group with baseline and 12 months of follow-up were included for analysis. They were divided into Every Visit (n=339) and <Every Visit (n=268) groups based on whether they had a treatment supporter for all 5 or for <5 follow-up visits, respectively. Outcomes were stratified between groups and tested for significance using a generalized linear mixed-effects model. A survey investigating participant satisfaction with their treatment supporter was administered at 12 months. Groups were majority female (53% versus 62%) with a mean age of 63 and 66 years. Country of origin differed between groups (22% versus 86%; Colombia). A 15.5% ([95% CI, 6.2%-24.8%] P=0.004) greater increase in statin medication use was reported in the Every Visit group at 12 months compared with the <Every Visit group. Sixty-one percent versus 48.2% of participants reported high medication adherence at 12 months (P<0.003). The difference in change in systolic blood pressure between groups was not found to be significant at 12 months, though it favored the Every Visit group (-2.3 [95% CI, -6.1 to 1.5]; P=0.045). The majority of survey respondents from either study group strongly agreed that having a treatment supporter positively influenced their health. Long-term support from a nominated treatment supporter was associated with improved adherence, risk factor management, and medication use among individuals with hypertension. URL: https://www.clinicaltrials.gov; Unique identifier: NCT01826019.

Exercise-induced potentiation of the acute hypoxic ventilatory response: Neural mechanisms and implications for cerebral blood flow.

A given dose of hypoxia causes a greater increase in pulmonary ventilation during physical exercise than during rest, representing an exercise-induced potentiation of the acute hypoxic ventilatory response (HVR). This phenomenon occurs independently from hypoxic blood entering the contracting skeletal muscle circulation or metabolic byproducts leaving skeletal muscles, supporting the contention that neural mechanisms per se can mediate the HVR when humoral mechanisms are not at play. However, multiple neural mechanisms might be interacting intricately. First, we discuss the neural mechanisms involved in the ventilatory response to hypoxic exercise and their potential interactions. Current evidence does not support an interaction between the carotid chemoreflex and central command. In contrast, findings from some studies support synergistic interactions between the carotid chemoreflex and the muscle mechano- and metaboreflexes. Second, we propose hypotheses about potential mechanisms underlying neural interactions, including spatial and temporal summation of afferent signals into the medulla, short-term potentiation and sympathetically induced activation of the carotid chemoreceptors. Lastly, we ponder how exercise-induced potentiation of the HVR results in hyperventilation-induced hypocapnia, which influences cerebral blood flow regulation, with multifaceted potential consequences, including deleterious (increased central fatigue and impaired cognitive performance), inert (unchanged exercise) and beneficial effects (protection against excessive cerebral perfusion).

Effect Mechanism of Electrocardiogram-Based Intravenous Single-Walled Carbon Nanotubes on Cardiac Function

This research was aimed to adopt electrocardiogram (ECG) and other techniques to explore the effects and mechanisms of single-walled carbon nanotubes (SWCNTs) and their carboxylation modification (C-SWCNTs) on cardiac function in rats. The SWCNTs were oxidized to C-SWCNTs by concentrated sulfuric acid and concentrated nitric acid. The morphology, surface charge, surface group, and water dispersibility of the samples were characterized. Subsequently, 40 SD rats in a 1:1:1:1 ratio were assigned into sham (intravenous injection of 5% glucose), SWCNT (intravenous injection of 2 mg/mL SWCNT glucose dispersion), C-SWCNT (intravenous injection of 2 mg/mL C-SWCNT glucose dispersion), and C-SWCNT+YM groups (treatment in C-SWCNT group was supplemented with an additional 1 mg/mL store-operated calcium entry (SOCE) blocker YM-58483/BTP2). The tail arterial pressure of rats in each group was detected. Left heart function and hemodynamics were detected by cardiac color ultrasonography. Heart parameters were detected by ECG lead II, and the pathological morphology of the heart was detected by hematoxylin-eosin staining. The levels of proteins related to the cardiac calcium signaling were detected by western blot. The results showed that the particle size distributions of SWCNTs and C-SWCNTs were uniform, and C-SWCNTs had better water dispersibility and a negatively charged surface. The results of caudal arterial pressure showed that SBP, DBP, and MBP of the caudal arteries in the SWCNT and C-SWCNT groups were markedly superior to those in sham group (P &lt; 0.05). Cardiac function results showed drastic decreases in LVDd, EF, EDV, SV, and CO and great increases in LVDs, AV-BVmax, and PV-BVmax in the SWCNT and C-SWCNT groups relative to sham group (P &lt; 0.05). The ECG results showed that relative to those in sham group, the amplitudes of the P wave and ST segment in the SWCNT and C-SWCNT groups were increased, the QRS and RR intervals were greatly prolonged, and the amplitude of the R wave was greatly decreased (P &lt; 0.05). Western blot results showed that the SWCNT and C-SWCNT groups had drastically increased protein levels of ORAI-1 and STIM-1 in the heart versus sham group (P &lt; 0.05). The changes in various cardiac parameters in C-SWCNT group were more prominent, and the cardiac pathological score increased markedly versus that in SWCNT group. The protein levels of ORAI-1 and STIM-1 increased notably (P &lt; 0.05). The changes in various cardiac parameters in C-SWCNT+YM group were notably enhanced versus those in the SWCNT and C-SWCNT groups, the cardiac pathological score was obviously reduced, and the protein levels of ORAI-1 and STIM-1 were substantially decreased (P &lt; 0.05). SWCNTs and C-SWCNTs both had cardiotoxic effects in rats, and C-SWCNTs had more obvious toxic effects. Nevertheless, the SOCE inhibitor YM-58483/BTP2 was able to enhance C-SWCNT-induced cardiac dysfunction by inhibiting the expression of calcium signaling-related proteins and affecting the changes in ECG parameters.

A prospective study of sexual risk patterns associated with delinquency and justice involvement among child welfare system-involved male adolescents in the United States.

Early sexual activity and teen pregnancy are known risk factors for delinquency and justice involvement among male adolescents. However, less is known about these patterns among child welfare system (CWS)-involved boys who face significant social barriers and past/current traumatic experiences. We prospectively examined these associations among male adolescents who identified as low and high risk for child-maltreatment via a secondary data analysis of the Longitudinal Studies of Child Abuse and Neglect dataset-a large scale assessment of children, their parents, and their teachers in the United States to understand issues of child abuse and neglect. We extracted and examined data from 657 boys who were identified as at-risk for maltreatment or with histories of substantiated maltreatment at ages 6, 8, 12, 14, and 16. We used structural equation modeling to examine the relationship between sexual activity (i.e., age of sexual debut, actively having sex, and sex resulting in a child) and changes in delinquency and justice involvement. Male adolescents who have engaged in sex and/or have fathered a child had greater increases in delinquency over time compared to those who have not had sex. Further, fathering a child was significantly associated with justice involvement, especially for the high-risk group. Results indicate that greater efforts should be taken to ascertain CWS-involved male adolescents' sexual health practices and parenting status. Male adolescents in the CWS require support with accessing developmentally appropriate sexual health education and family services.

Reparameterizing Litter Decomposition Using a Simplified Monte Carlo Method Improves Litter Decay Simulated by a Microbial Model and Alters Bioenergy Soil Carbon Estimates

AbstractLitter decomposition determines soil organic matter (SOM) formation and plant‐available nutrient cycles. Therefore, accurate model representation of litter decomposition is critical to improving soil carbon (C) projections of bioenergy feedstocks. Soil C models that simulate microbial physiology (i.e., microbial models) are new to bioenergy agriculture, and their parameterization is often based on small datasets or manual calibration to reach benchmarks. Here, we reparameterized litter decomposition in a microbial soil C model (CORPSE ‐ Carbon, Organisms, Rhizosphere, and Protection in the Soil Environment) using the continental‐scale Long‐term Inter‐site Decomposition Experiment Team (LIDET) dataset which documents decomposition across a range of litter qualities over a decade. We conducted a simplified Monte Carlo simulation that constrained parameter values to reduce computational costs. The LIDET‐derived parameters improved modeled C and nitrogen (N) remaining, decomposition rates, and litter mean residence times as compared to Baseline parameters. We applied the LIDET litter decomposition parameters to a microbial bioenergy model (Fixation and Uptake of Nitrogen – Bioenergy Carbon, Rhizosphere, Organisms, and Protection) to examine soil C estimates generated by Baseline and LIDET parameters. LIDET parameters increased estimated soil C in bioenergy feedstocks, with even greater increases under elevated plant inputs (i.e., by increasing residue, N fertilization). This was due to the integrated effects of plant litter quantity, quality, and agricultural practices (tillage, fertilization). Collectively, we developed a simple framework for using large‐scale datasets to inform the parameterization of microbial models that impacts projections of soil C for bioenergy feedstocks.

Composite Restoration Design Effect During Curing and Chewing.

The purpose of this work is to observe the effect of the cavity design of the direct composite restoration on a real case of the patient's tooth structures after applying his mandibular kinematics with finite element analysis. Four complex maxillomandibular models of teeth 17 and 47 were constructed from the patient's cone-beam acquisition and the patient's kinematic data recorded with Modjaw® were added. Different shapes and sizes of mesio-occluso-distal (M.O.D.) composite restorations were simulated, including the polymerization shrinkage of this material. Finite element analyses were used to observe the Von Mises stresses occurring during polymerization and mastication. The stresses were observed at the cavity margin and the amplitude of the stresses was higher when the enamel volume was lower. The reduction in occlusal enamel volume with the open-angle vestibular and palatal walls resulted in a greater increase in stresses observed on the structures. The occlusal enamel is the area that bears the maximum masticatory stress, the loss of this enamel volume generates a much greater concentration of stress on the underlying structures. It is important to preserve as much enamel tissue as possible when designing a cavity for a direct composite restoration.

Превращение комбинированного сырья на цеолитсодержащих катализаторах

The article discusses the ways of rational use of hydrocarbon raw materials in order to obtain isoparaffin and aromatic hydrocarbons. The possibilities of joint processing of the 75-100°C fraction have been studied from gas condensate and propane-butane fraction (PBF) in an anhydrous environment and in the presence of a modified zeolite-containing catalyst. The regularities of the yield of aromatic and isoparaffinic hydrocarbons of the anhydrous process of catalytic conversion of combined hydrocarbon raw materials on a zeolite-containing Pt/Beta catalyst modified by 0.5% wt have been established platinum. So, when converting a fraction of 75-100°C. With a temperature range of 300-350°C, the content of isoparaffins in liquid products increases by more than 20% by weight. A further increase in temperature is accompanied to a greater extent by the formation of aromatic hydrocarbons. The total content of benzene, toluene, xylenes is about 20% by weight. Similar trends are observed when testing the propane-butane fraction. The greatest increase in isoparaffin hydrocarbons is also observed at a temperature of 300°C. Their content in liquid and gaseous products increases by an average of 10%. The main share in this process is accounted for by iso-butane. Accordingly, an increase in the reaction temperature by 100°C increases the formation of benzene and toluene by 11% by weight. More significant results were obtained during the joint transformation of the 75-100°C fraction and the propane-butane fraction. At a reaction temperature of 300°C, a high content of iso-butane is observed in gaseous products, which allows them to be involved in petrochemical processes. The content of isoparaffins in liquid products increases by 50% by weight, which makes them valuable as a high-octane component of motor fuels. Favorable temperatures for the production of aromatic hydrocarbons are 400°C and above.