Gradual Increase Research Articles

The spatial correlation of economic institutional change in China and its impact on economic growth: A social network analysis approach.

Economic institutional change is a vital driving force behind the rapid rise of China's economy. However, the incremental approach to economic institutional change has caused unbalanced transformation and economic growth. To this end, we adopted the entropy method to measure the economic institutional change index, and employed social network analysis to reveal its spatial correlation characteristics. We then applied QAP analysis to empirically demonstrate the impact of China's economic institutional change on regional disparities in economic growth. The findings indicated a gradual increase in the level of economic institutions over time and a spatial gradient between the eastern, central, and western regions. Moreover, the spatial correlation network of China's economic institutional change is stable and gradually improving. Nevertheless, the role of provinces in the process of economic institutional change varies: the eastern coastal provinces play a dominant role, the central and western provinces benefit to a lesser extent, and some provinces in northeastern China play a "bridging" and "intermediary" role. Regional differences in China's economic institutional change have widened the regional disparities in China's economic growth, and the impact of each dimension of economic institutions on regional disparities in economic growth is characterized by phases.

Revealing pest patterns: A comparative spatial distribution analysis of insect threats in Kharif rice across the key agricultural regions in the Eastern India.

This study investigates the spatial distribution and aggregation patterns of major insect pests in Kharif rice fields during the 2023 growing season in Eastern India. The analysis focuses on key pests such as yellow stem borer (YSB), gall midge, green leaf hopper (GLH), and brown planthopper (BPH), as well as rice thrips, caseworm, whorl maggot, Gundhi bug, grasshopper, and leaf folder. Using statistical indices, this study aims to understand pest behavior across Standard Meteorological Weeks (SMWs) to better inform pest control strategies. The study reveals significant clustering and aggregation patterns among the pests. YSB exhibited variance-mean ratio (VMR) values between 1.14 (40th SMW) and 1.96 (31st SMW), with dispersion parameter (K) values ranging from 0.57 to 21.65, and a peak index of dispersion of 132.66 (43rd SMW). Similarly, gall midge showed VMR values from 6.19 to 10.48, whereas GLH and BPH recorded VMR ranges of 1.19 to 132.10 and 1.01 to 1.50, respectively. These spatial distribution trends were confirmed through values for Iwao's patchiness index and Taylor's power law, indicating strong pest aggregation in specific areas. The results underscore the need for region-specific integrated pest management strategies that take into account pest clustering and environmental factors influencing pest distribution. Although an S-curve pattern of infestation-showing gradual population increases, rapid peaks, and eventual decline-was observed, the primary focus remains spatial patterns, which are critical for optimizing pest management and improving rice crop sustainability in the region. © 2024 Society of Chemical Industry.

Calibrating lower-middle Miocene mammal faunas and unravelling climate change during the Miocene Climate Optimum: the Bardenas Reales de Navarra record (Ebro basin, NE Iberian Peninsula)

AbstractThe chronology of lower Miocene Iberian small mammal faunas is still poorly constrained given the scarcity of well dated sedimentary successions including small mammal fossil localities. Such scarcity has prevented also an accurate understanding of the response of European terrestrial ecosystem to global changes across the Miocene climate optimum (MCO), one of the best analogues of present-day global warming. Here we present an updated fossil small mammal record of the Bardenas Reales de Navarra (western Ebro basin, Spain), where an expanded lower to middle Miocene continental succession is superbly exposed. Previous and new magnetostratigraphic results from this succession have enabled us to propose, along with additional magnetostratigraphically-dated Iberian faunas, a new chronology for local zones Y to D (Mammal Neogene zones MN2 to MN5). In addition to that, the studied small mammal faunas point to a gradual increase in temperature and humidity conditions in SW Europe between 20 and 15.5 Ma, which appears to be coupled with the progressive shift towards warmer regional (Atlantic) and global conditions across the MCO, thereby pointing to gradual changes in oceanic circulation as the main driver of this period of global warmth. The evolution of sedimentary facies appears to indicate a threshold response of the Ebro basin hydrological balance to the MCO, whereas pedogenic formation of magnetic minerals seems to be linked to periods of enhanced climate variability. These results highlight the need of combining different paleoenvironmental indicators in order to obtain a reliable view of the response of continental ecosystems to global warming.

Texas trade in forest products industry

Texas boasts abundant forest resources, providing substantial economic and ecological benefits statewide. This study examines the trends in forest product trade within Texas over the past two decades, focusing on key disruptions during this period. The analysis categorizes the forest products industry into two main markets: solid wood and paper and pulp, further dividing the industry into five core sectors. The findings indicate that Texas operates as a net importer of solid wood and wood furniture products while serving as a net exporter of wood pulp and, paper and paperboard products. Both import and export values have generally shown a gradual increase over time. Notably, Mexico emerged as Texas’s primary trade partner for both imports and exports in 2023. Additionally, Texas ranks as the second-largest exporter of paper and paperboard products nationally while also being the second-largest importer of solid wood products and wood furniture products. The study highlights the profound impact of the COVID-19 pandemic response on Texas’s trade dynamics, emphasizing the crucial need for ongoing monitoring of trade policies and international relationships. These factors have the potential to exert significant influence on Texas’s trade landscape in the foreseeable future.

Experimental Study of Erosion Prevention Model by Bio-Cement Sand

Microbially induced carbonate precipitation (MICP) technology is employed to reinforce the surface soil of a dam, aiming to prevent erosion caused by water flow and damage to the dam slope. The relationship between penetration depth, calcium carbonate content, and bonding depth was investigated at eight measuring points on the sand slope surface of a mold under different reinforcement durations. It was observed that as grouting reinforcement times increased, there was a gradual increase in calcium carbonate content but a rapid rise in penetration resistance. Moreover, the bonding depth of sand on the bio-reinforced sand slope increased with higher levels of calcium carbonate content. Microbial grouting reinforcement enhanced soil particle bonding force, requiring water flow to overcome this force for activation of sand particles. Consequently, microbial grouting reinforcement significantly improved shear strength and critical starting flow velocity on sand slope surfaces. The experimental results demonstrated that after MICP surface treatment through spraying, a dense and water-stable hard shell layer composed of bonded calcium carbonate and soil particles formed continuously on sample surfaces, effectively enhancing the strength and erosion resistance of sandy soils. These findings provide reliable evidence for silt slope reinforcement and dam erosion prevention.

The Effect of Transition to Close-to-Nature Forestry on Growing Stock, Wood Increment and Harvest Possibilities of Forests in Slovakia

The aim of the study is to quantify the impacts of a possible transition to close-to-nature forestry in Slovakia and to compare the expected development of the total volume production, growing stock, merchantable wood increment and harvesting possibilities of forests in Slovakia with current conventional management using the FCarbon forest-growth model and available data from the Information System of Forest Management. The subject of the study was all forest stands available for wood supply (FAWS). The simulations were run in annual iterations using tree input data aggregated over 10-year-wide age classes. The calculation of wood increments was based on available growth models. In the business-as-usual (BAU) scenario, stock losses were based on the actual intensity of wood harvesting in the reference period 2013–2022. In the scenario of the transition to close-to-nature forest management, the losses were specifically modified from the usual harvesting regime at the beginning, to the target harvesting mode in selective forest at the end of the simulated period. With the modelling method used, a gradual increase in forest stocks occurred in both evaluated scenarios in the monitored period, namely by 10% in the case of BAU and by 23% in the case of close-to-nature forest management until 2050. In absolute mining volume, CTNF is by 5–10% lower than BAU management, with the difference gradually decreasing. The results show that the introduction of close-to-nature forest management will temporarily reduce the supply of wood to the market, but this reduction will not be significant and will be compensated by a higher total volume production, and thus also by increased carbon storage in forests.

DNA methylation at AHRR as a master predictor of smoke exposure and a biomarker for sleep and exercise

BackgroundDNA methylation profiling may provide a more accurate measure of the smoking status than self-report and may be useful in guiding clinical interventions and forensic investigations. In the current study, blood DNA methylation profiles of nearly 800 Polish individuals were assayed using Illuminia EPIC and the inference of smoking from epigenetic data was explored. In addition, we focused on the role of the AHRR gene as a top marker for smoking and investigated its responsiveness to other lifestyle behaviors.ResultsWe found > 450 significant CpGs associated with cigarette consumption, and overrepresented in various biological functions including cell communication, response to stress, blood vessel development, cell death, and atherosclerosis. The model consisting of cg05575921 in AHRR (p = 4.5 × 10–32) and three additional CpGs (cg09594361, cg21322436 in CNTNAP2 and cg09842685) was able to predict smoking status with a high accuracy of AUC = 0.8 in the test set. Importantly, a gradual increase in the probability of smoking was observed, starting from occasional smokers to regular heavy smokers. Furthermore, former smokers displayed the intermediate DNA methylation profiles compared to current and never smokers, and thus our results indicate the potential reversibility of DNA methylation after smoking cessation. The AHRR played a key role in a predictive analysis, explaining 21.5% of the variation in smoking. In addition, the AHRR methylation was analyzed for association with other modifiable lifestyle factors, and showed significance for sleep and physical activity. We also showed that the epigenetic score for smoking was significantly correlated with most of the epigenetic clocks tested, except for two first-generation clocks.ConclusionsOur study suggests that a more rapid return to never-smoker methylation levels after smoking cessation may be achievable in people who change their lifestyle in terms of physical activity and sleep duration. As cigarette smoking has been implicated in the literature as a leading cause of epigenetic aging and AHRR appears to be modifiable by multiple exogenous factors, it emerges as a promising target for intervention and investment.

Reproductive response of the predator Tenuisvalvae notata (Mulsant) (Coleoptera: Coccinellidae) to temperatures outside their ideal thermal range.

Global warming has driven changes in the biology and fitness of organisms that need to adapt to temperatures outside of their optimal range to survive. This study investigated aspects of reproduction and survival of the lady beetle Tenuisvalvae notata (Mulsant) (Coleoptera: Coccinellidae) subjected to temperatures that varied from its optimal (28°C) to a gradual decrease (12, 14, 16, and 18°C) and increase (32, 34, 35, and 36°C) over time at a rate of 1°C/day. Fertility, fecundity, oviposition period, and survival were determined. There was a significant reduction in fertility and fecundity at temperatures below 18°C and above 34°C, whereas survival was reduced only above 34°C. Additionally, we evaluated that fecundity was the lowest when females were kept at low temperature, and when males were kept under high temperature. Therefore, if the T. notata remained for a long period under exposure to temperatures outside the ideal range, then the species could present different reproductive responses for each sex to high and low temperatures. This factor must be considered when releasing natural enemies into an area to understand the effect of temperature on the decline of a local population a few generations after release.

Effect and mechanism of allergen-specific immunotherapy on small airway dysfunction in children with asthma.

The purpose of this study was to investigate the effectiveness of allergen-specific immunotherapy (AIT) on small airway dysfunction (SAD) and the underlying mechanism with a special focus on basophils. Sixty-five children with mild to moderate asthma who were under regular inhaled corticosteroid (ICS) treatment for more than 1 year but whose FEF75 remained below 65% of the predicted value and had positive results for serum Der p or Der f were enrolled. Children with asthma underwent house dust mite (HDM) subcutaneous immunotherapy (SCIT) treatment for 1 year. Clinical symptoms and lung function were evaluated every 3 months during HDM SCIT treatment. Basophil activation test (BAT) was carried out before and after HDM SCIT treatment. RNA sequencing was performed in isolated basophils from peripheral blood after 6 months of HDM SCIT treatment, followed by GO term and KEGG pathway enrichment analysis between patients with and without HDM SCIT treatment. HDM AIT treatment ameliorated clinical symptoms while concurrently improved lung function parameters, such as FEV1/FVC, FEF75, FEF50 and MMEF (p < .05). It is worth noting that FEF75 values showed a highly significant, gradual and persistent increase (from 49.55 ± 1.27% at baseline to 71.89 ± 2.64% after 1 year of therapy) and 22 of 35 patients no longer had SAD after 1 year of treatment. BAT results revealed that AIT treatment significantly reduced basophil activity to the inhalant allergen mixtures containing HDM in vitro challenge from baseline. GO term and KEGG pathway enrichment analysis of basophils revealed that downregulated genes were mainly involved in immune cell activation, antigen presentation, and Th2 cell differentiation. Our study demonstrated that HDM AIT not only improved SAD related lung function parameters, but also reduced basophil activity. RNA sequencing revealed the inhibition of phagocytosis and the phagosome pathway in basophils which may affect the polarization of Th2 cell differentiation after HDM AIT.

Exploration of the Photoluminescence Behavior and Emission Mechanism of Thioester Polyacrylamide Tablets During the Gradual Increase of Molecular Weight.

To enhance the photoluminescence (PL) of unconventional luminescent compounds, particularly their persistent room temperature phosphorescence (p-RTP) performance, compressing the powder into tablets has been demonstrated as a viable approach. Nevertheless, the alterations in the emission capability of PL in compacted tablets have not been comprehensively investigated. In this study, four polyacrylamide (PAM) with controllable molecular weight (MW) are fabricated from powder to tablets, and their PL emission properties are thoroughly examined and compared with corresponding powders to elucidate the emission mechanism. As MW increases, both PL and p-RTP emissions of the tablets gradually intensify, exhibiting significant enhancement compared to the corresponding powder while retaining the characteristic blue shift. Through small angle X-ray scattering (SAXS), construction of molecular models for tablets, detailed analysis of molecular interactions, and theoretical calculations are conducted to reasonably explain these emission phenomena using clustering-triggered emission (CTE) and average packing density promoted emission (PDE) mechanisms. These findings not only advance the understanding of nonconventional luminogens' emission mechanisms but also offer new insights for preparing nonconventional luminescent polymers with controllable p-RTP emission performance.

Sequence characteristics, expression and subcellular localization of PtCYP721A57 gene from cytochrome P450 family in Polygala tenuifolia willd.

The Cytochrome P450 (CYP450) family is the largest enzyme protein family in plants, distributed across various organs and involved in significant catalytic activities in primary and secondary metabolic processes. In this study, we cloned the PtCYP721A57 gene, characterized its open reading frame (ORF), and conducted comprehensive analyses including physicochemical properties, evolutionary relationships, subcellular localization, prokaryotic expression, and correlation between the relative expression of different parts and the content of tenuifolin, hormones, and abiotic stress response associated with the encoded protein. The ORF of PtCYP721A57 was 1,521 bp, with a secondary structure predominantly composed of α-helices and random coils. Subcellular localization experiments confirmed the presence of PtCYP721A57 in the endoplasmic reticulum. For prokaryotic expression, we constructed the recombinant plasmid pET28a-PtCYP721A57 using pET28a as the vector, which was then transformed into BL21(DE3). Induction with Isopropyl β-D-1-thiogalactopyranoside (IPTG) at temperatures of 16 and 25 °C and varying concentrations (0.1, 0.2, 0.5, 1, 2 mM) resulted in the formation of inclusion bodies, with higher expression observed at 25 °C. Our qPCR analyses revealed that PtCYP721A57 exhibited the highest expression in the cortex of Polygala tenuifolia, followed by roots and xylem, correlating with the observed tenuifolin content distribution. Induction with abscisic acid (ABA) and chitosan (CHT) initially decreased PtCYP721A57 expression followed by a subsequent increase, peaking at 48 h. Similarly, drought stress induced a gradual increase in PtCYP721A57 expression, also peaking at 48 h. NaCl treatment for 6 h significantly upregulated PtCYP721A57 expression. In conclusion, our study provides foundational insights into the PtCYP721A57 gene in Polygala tenuifolia, laying the groundwork for further exploration of its role in the biosynthesis pathway of triterpenoid saponins.

Global, Regional, and National Burden of Nonrheumatic Valvular Heart Disease and Its Attributable Risk Factors in 204 Countries and Territories, 1990 to 2019: Results From the Global Burden of Disease Study 2019.

Nonrheumatic valvular heart disease (NRVD) is increasingly becoming a significant public health concern, particularly among older people. In the context of population aging, a detailed report on the epidemiological trends of NRVD is crucial for policymakers to effectively allocate health care resources. This study aimed to explore these trends using data from the GBD (Global Burden of Disease) 2019 study. We assessed the changing trends of the incidence, mortality, and disability-adjusted life years rates for NRVD by calculating the estimated annual percentage change for each. Additionally, we examined the impact of a region's level of social development on NRVD epidemiological trends and identified key risk factors contributing to NRVD-related deaths. Between 1990 and 2019, the global incidence of NRVD showed a gradual increase, with an estimated annual percentage change of 0.39 (95% CI, 0.30-0.48). The data revealed that women and older people are more likely to develop NRVD. High-sociodemographic index countries exhibited higher age-standardized incidence and mortality rates compared with low- and middle-sociodemographic index countries. The most significant risk factor for NRVD-related mortality was identified as high systolic blood pressure. Over the past 3 decades, the burden of NRVD has intensified, indicating a need for more health care resources to address this issue, which is closely associated with an aging population. Currently, high-sociodemographic index countries report the highest incidences and deaths due to NRVD. However, low- and middle-sociodemographic index countries should also implement measures to manage the rapidly increasing burden of NRVD.

Performance of Black gram (Vigna mungo L. Hepper) under Different Levels of Phosphorus at Bardiya, Nepal

A field experiment was conducted during the spring season of 2023 in Badhaiyatal Rural Municipality-7, Bardiya district to evaluate the performance of black gram at various levels of phosphorus. A randomized complete block design (RCBD) consisting of four treatments and five replications were used for the study. The treatments consisted of different levels of phosphorous viz. 0 Kg ha-1 (control), 20 Kg ha-1, 40 Kg ha-1 and 60 Kg ha-1. Black gram var. BLG 0093-1 was sown at spacing of 40 cm x 5 cm in the plots sized 8 m2. All the growth parameters and yield obtained from each treatment were compared at 5% level of significance. The results showed significantly greater number of branches (13.84), flower buds (11.33), root length (16.27 cm) and secondary roots (16.05) at 60 Kg phosphorus per ha followed by 40 Kg ha-1. However, plant height, pods per plant, seeds per pod, weight of pods per plant, biomass and grain yield showed non-significant results at similar levels of phosphorus (60 Kg ha-1). Though non-significant, higher number of fruiting branch, number of nodules, effective nodules, 1000 grain weight and harvest index were observed at 40 Kg ha-1 phosphorus. The findings suggested a gradual increase in the yield with increasing levels of phosphorus with the highest gross return from 60 Kg ha-1 phosphorus. However, since the variation in grain yield among the treatments was not significant, the cost involved with the 60 Kg ha-1 was greater as compared to 40 Kg ha-1 phosphorus, greater benefit was observed with the latter. So, on grounds of greater net return and better BC ratio, 40 Kg ha-1 phosphorus seems to be more profitable for the farmers.

Actual situation of nutritional management and factors related to activities of daily living ability at discharge in convalescent rehabilitation ward.

In this study, we aimed to investigate changes in the Geriatric Nutritional Risk Index (GNRI), a nutrition-related prognostic indicator, in our convalescent rehabilitation ward and determine how this index relates to activities of daily living (ADL) ability at discharge. We retrospectively analyzed data of 107 patients admitted to our convalescent rehabilitation ward between April and September 2023. We used the GNRI as the nutritional risk index and Functional Independence Measure (FIM) as the ADL index. The patients' mean age was 80.0 ± 10.3 years; 38 were males and 69 females. The patients' mean body weight at admission was 51.2 ± 10.2 kg, which significantly decreased to 50.2 ± 9.4 kg at discharge (p = 0.0006). Their mean body mass index (BMI) also significantly decreased from 21.4 ± 3.4 at admission to 20.0 ± 8.2 at discharge (p = 0.002). The mean GNRI significantly decreased from 93.1 ± 8.6 at admission to 91.7 ± 8.4 at discharge (p = 0.023). The mean body weight decreased until the fourth month after admission; however, no decreasing trend after the fifth month was observed. The mean monthly energy intake gradually increased after admission and reached the calculated energy requirement of 1,415 ± 22 kcal at the fifth month. Multivariate analysis demonstrated that at discharge, the GNRI score was positively associated with the FIM score (β = 0.21, p = 0.0008). Body weight and GNRI scores decreased after admission but stopped decreasing after the fifth month due to a gradual increase in energy intake. At discharge, the FIM score was positively associated with the GNRI score. We expected that active nutritional therapy from the beginning of hospitalization would increase the GNRI by the time of discharge and eventually improve ADL ability at discharge.

Application of 18F-fluorodeoxyglucose PET/computed tomography in the diagnosis of infiltrative subsolid nodules in lung adenocarcinoma

Purpose To investigate the diagnostic value of 18F-fluorodeoxyglucose(FDG) PET/computed tomography (CT) for infiltrative subsolid nodules at different stages of lung adenocarcinoma and to explore predictive factors for invasive adenocarcinoma, providing compelling evidence for timely intervention. Methods A retrospective analysis was conducted on PET/CT imaging data of 170 subsolid nodules lesions confirmed postoperatively as lung adenocarcinoma or precursor glandular lesions. Lesions were categorized into preinvasive lesions including atypical adenomatous hyperplasia and adenocarcinoma in situ, microinvasive adenocarcinoma, and invasive adenocarcinoma. Compared the differences in imaging features and metabolic parameters among different groups and used a multifactor logistic regression model and receiver operating characteristic curve analysis to identify predictive factors for invasive adenocarcinoma. Results From preinvasive lesions through microinvasive adenocarcinoma to invasive adenocarcinoma, there was a gradual increase in nodule diameter, nodule area, and proportion of part-solid nodule. Statistical significance (P &lt; 0.05) was observed in the rates of spiculation and pleural indentation between preinvasive lesions versus microinvasive adenocarcinoma and invasive adenocarcinoma groups. The maximum standardized uptake value and maximum standardized uptake ratio show statistically significant differences (P &lt; 0.05) between the invasive adenocarcinoma group and the other groups. Logistic regression analysis indicated that nodule composition, nodule diameter, and maximum standardized uptake ratio were predictive factors for invasive adenocarcinoma (P &lt; 0.05). For part-solid nodules, the longest diameter of the solid component has a high diagnostic value. Conclusion The imaging features of 18F-FDG PET/CT contribute to the diagnosis of infiltrative subsolid nodules at different stages of lung adenocarcinoma, providing robust evidence for timely intervention.

Amplification of Protein Expression by Self-Amplifying mRNA Delivered in Lipid Nanoparticles Containing a β-Aminoester Ionizable Lipid Correlates with Reduced Innate Immune Activation.

Self-amplifying mRNA (saRNA) is witnessing increased interest as a platform technology for protein replacement therapy, gene editing, immunotherapy, and vaccination. saRNA can replicate itself inside cells, leading to a higher and more sustained production of the desired protein at a lower dose. Controlling innate immune activation, however, is crucial to suppress unwanted inflammation upon delivery and self-replication of RNA in vivo. In this study, we report on a class of β-aminoester lipids (βAELs) synthesized through the Michael addition of an acrylate to diethanolamine, followed by esterification with fatty acids. These lipids possessed one or two ionizable amines, depending on the use of nonionic or amine-containing acrylates. We utilized βAELs for encapsulating saRNA in lipid nanoparticles (LNPs) and evaluated their transfection efficiency in vitro and in vivo in mice, while comparing them to LNPs containing ALC-0315 as an ionizable lipid reference. Among the tested lipids, OC7, which comprises two unsaturated oleoyl alkyl chains and an ionizable azepanyl motif, emerged as a βAEL with low cytotoxicity and immunogenicity relative to ALC-0315. Interestingly, saRNA delivered via the OC7 LNP exhibited a distinct in vivo transfection profile. Initially, intramuscular injection of OC7 LNP resulted in low protein expression shortly after administration, followed by a gradual increase over a period of up to 7 days. This pattern is indicative of successful self-amplification of saRNA. In contrast, saRNA delivered via ALC-0315 LNP demonstrated high protein translation initially, which gradually declined over time and lacked the amplification seen with OC7 LNP. We observed that, in contrast to saRNA OC7 LNP, saRNA ALC-0315 LNP induced potent innate immune activation by triggering cytoplasmic RIG-I-like receptors (RLRs), likely due to the highly efficient endosomal membrane rupturing properties of ALC-0315 LNP. Consequently, the massive production of type I interferons quickly hindered the amplification of the saRNA. Our findings highlight the critical role of the choice of ionizable lipid for saRNA formulation in LNPs, particularly in shaping the qualitative profile of protein expression. For applications where minimizing inflammation is desired, the use of ionizable lipids, such as the βAEL reported in this study, that elicit a low type I interferon response in saRNA LNP is crucial.

Gender Lens Investing: A Scoping Review from Theoretical Foundations to Public Equity Applications

This scoping review explores the dynamic field of Gender Lens Investing (GLI), examining its evolution from a niche approach to its current status as a widely recognized investment strategy with the potential to contribute to sustainable development and yield social, financial, and economic benefits. This study provides a comprehensive overview of the theoretical foundations of GLI and its practical applications across public equity markets. By conducting research across four major databases, we performed a thematic analysis that identified four principal themes: Benefits and Impacts, GLI Strategies, GLI Instruments and Innovations, and Challenges and Barriers to Implementation. Key findings reveal an increased implementation of GLI in various forms and a gradual increase in publications, reflecting growing interest within academia and industry. Despite these advancements, critical gaps remain in understanding the financial and social impacts of GLI strategies and instruments. While GLI has been broadly defined and implemented, further empirical research is necessary to evaluate the effectiveness of GLI in public equities and its long-term impacts. The limitations of this review include a focus on English-language publications, which might limit the comprehensiveness of the analysis.

Importance of environmental signals for cardiac morphological development in Atlantic salmon.

The hearts of salmonids display remarkable plasticity, adapting to various environmental factors that influence cardiac function and demand. For instance, in response to cold temperature, the salmonid heart undergoes growth and remodeling to counterbalance the reduced contractile function associated with dropping temperatures. Alongside heart size, the distinct pyramidal shape of the wild salmonid heart is essential for optimal cardiac performance, yet the environmental drivers behind this optimal cardiac morphology remain to be fully understood. Intriguingly, farmed salmonids often have rounded, asymmetrical ventricles and misaligned bulbi from an early age. These deformities are noteworthy given that farmed salmon are often not exposed to natural cues, such as a gradual temperature increase and changing day lengths, during critical developmental stages. In this study, we investigated whether natural environmental conditions during early life stages are pivotal for proper cardiac morphology. Atlantic salmon were raised under simulated natural conditions (low temperature with a natural photoperiod; SimNat) and compared with those reared under simulated farming conditions (SimFarm). Our findings reveal that the ventricle shape and bulbus alignment in SimNat fish closely resemble those of wild salmon, while functional analyses indicate significant differences between SimNat and SimFarm hearts, suggesting diastolic dysfunction and higher cardiac workload in SimFarm hearts. These findings highlight the profound influence of environmental factors such as water temperature and photoperiod on the structural development of the salmonid heart, underscoring the importance of early environmental conditions for cardiac health.

Evaluating physical outcomes in elderly sport and dance rollator users

The present single-arm pilot study investigates the effects of a video-based dance intervention on physical outcomes in elderly individuals utilizing sports and dance rollators. In addition, the dance videos used in the current study are intended to integrate into the future Intercommunication Technology (ICT)-Rollator for the elderly. The aim is to evaluate the physical outcomes (such as gait, balance, mobility, and hand grip strength) during guided movement training (dance) using a video projected in a laboratory setting. The pilot study involved six elderly rollator users (aged 85 and above). In the initial assessment, subjects were screened for mobility and coordination limitations prior to pre-testing using a four-square-step test and the SF-36 questionnaire. Both pre-testing and post-testing included assessments of mobility, balance, and spatiotemporal gait parameters using the Timed Up-and-Go (TUG) test, Berg Balance Scale (BBS), and the Optogait system, respectively. Hand grip strength was measured using a hand dynamometer and reaction time was measured using a pipe-drop test. Blood pressure was monitored every 15 minutes during the training sessions to prevent adverse events, maintaining an upper range of 140-150/90-96. Adherence rates were measured based on the total duration of activity, calories burned per session, and dropout rates. Post-session questionnaires were administered to verify the respondents' qualitative evaluations of their degrees of exhaustion, enjoyment, impediments, facilitators, and suggested changes. The intervention included heart rate monitoring, which revealed gradual and slight increases in heart rate intensity and gradual decreases in heart rate ranges (HRR) during the dance sessions. The results indicate improvements in balance, mobility, gait, and adherence rates. Future longitudinal research will further examine the effectiveness of the dance intervention using the ICT-Rollator, comparing it to a control group using a conventional rollator. The ICT-Rollator could be a unique rehabilitation aid for the elderly, offering promising improvements.

Enhancing ecosystem dynamics: organic and regenerative practices in rice–wheat systems and their impact on soil arthropod biodiversity

Arthropods may make a significant fraction of the total number of soil organisms. They function as plant litter transformers or ecosystem engineers, and thus contribute positively to soil health. The present study was conducted during the 2020–2022 at International Rice Research Institute, South Asia Regional Centre, Varanasi. Study investigates the impact of different farming methods-conventional (Scenario 1; Sc1), LINF- Low-input natural farming (Sc 2); BBEF- Biochar-based ecological farming (Sc 3); CROF- Climate-resilient organic farming (Sc 4); RF- Regenerative farming (Sc 5) practices on soil arthropod populations in rice-wheat systems. Study utilized pitfall traps across various experimental setups. The findings revealed a significant increase in arthropod diversity and abundance, particularly in organic farming scenarios, where the Formicidae family (ants) and the Araneae family (spiders) were most prevalent. In an organically rich soil system, the five most diverse groups (Isopoda, Myriapoda, Insecta, Acari, and Collembola) were reported. This increase can be attributed to the nutrient-rich amendments that positively influence soil organisms. This study highlights a gradual increase in specific taxa, such as cockroaches, spiders, ants, and grasshoppers, following the transition to organic farming. Principal component analysis (PCA) further revealed distinct arthropod distribution patterns in the different farming systems, indicating the unique ecological impact of each method. Interestingly, predator populations in zero-till wheat fields under regenerative agriculture were greater than those in conventionally tilled fields. These results underscore the substantial role of organic and regenerative farming practices in promoting sustainable agricultural ecosystems. This study reveals the complex interplay between farming practices and arthropod dynamics and highlights the ecological benefits of sustainable agricultural methods, emphasizing their potential to enhance biodiversity and ecosystem health.