Glue Material Research Articles

Comparative Study of Safety and Efficacy of α-n-Butyl-2-cyanoacrylate Glue versus Traditional Embolization Materials in the Treatment of Acute Renal Hemorrhage.

Aims/Background This study aims to evaluate the safety and efficacy of α-n-butyl-2-cyanoacrylate (NBCA) glue in comparison with traditional embolization materials for the treatment of acute renal hemorrhage. Methods A total of 105 patients with the acute renal hemorrhage who underwent superselective renal artery embolization were enrolled. The patients were divided into two groups based on the embolization materials used: the traditional group (43 cases, control group) and the medical glue group (62 cases, observation group). Demographic characteristics, medical history, preoperative and postoperative 24-hour blood counts, renal function, and other clinical data were collected. The safety and efficacy of the two treatment methods were then compared between the groups. Results No significant difference in efficacy was observed between the traditional group and the medical glue group (p > 0.05). However, significant differences were found between the two groups in terms of embolization vessel grade, systemic immune-inflammation index (SII) difference, estimated glomerular filtration rate (eGFR) difference, and combined eGFR difference (p < 0.05). The traditional group exhibited a higher postoperative inflammatory response and greater renal function damage compared to the medical glue group. The degree of vascular embolization also influenced the extent of postoperative inflammatory response and renal function damage in patients with acute renal hemorrhage. Conclusion Compared to traditional embolization materials, NBCA glue demonstrates a clear hemostatic effect in the treatment of patients with acute renal hemorrhage, while also leading to reduced postoperative inflammatory response and renal function damage. NBCA adhesive is both safe and effective for treating acute renal hemorrhage.

Vein of Galen Aneurysmal Malformations: Updates on Technical Aspects and Functional Outcomes Post-Endovascular Treatment—A Systematic Review and Meta-Analysis

Background and Objectives: Vein of Galen aneurysmal malformations (VGAMs) represent the most common vascular malformations of the brain at the pediatric age. Comprehension of its angioarchitecture and clinical features may influence their treatment options and functional outcomes. The aim of this review is to give an update of the anatomical and technical aspects of the management of VGAMs after endovascular treatment. Materials and Methods: We conducted a systematic review of original articles published between 1 January 2014 and 1 February 2024 in Pubmed, Web of Science (WOS), and Scopus databases following PRISMA guidelines. Variables such as age, sex, angioarchitecture of the malformation, clinical presentation, embolization technique, rate of occlusion, post-procedural complications, follow-up time, and mortality were collected. Random-effect meta-analysis of proportions was performed. Results: Fifteen studies on a total of 400 patients with VGAMs were collected. A total of 65.1% was male. The age at diagnosis was 12% prenatal, 35.5% neonates, 34.1% infants, 15.1% children, and 3.3% adults. Clinical presentation included 31.4% increased head size, 25.7% congestive heart failure, 12.9% neurological deficits, 10% seizures, 9.3% prominence of facial veins, and 8.9% developmental delay. A total of 339 patients underwent endovascular treatment (84.8%) with an average of 2.1 procedures per patient. The embolization technique was defined by transarterial access and glue material. Radiological occlusion was complete in 62.3% of the patients. The most frequent periprocedural incidents included hemorrhagic events (28.4%), embolization material migration (25.7%), and death (22%). The functional outcome was good in 68% of the surviving patients. The average follow-up time was 43.18 months. High heterogeneity was found in all outcomes but mortality rate. Conclusions: The angioarchitecture of VGAMs is significantly important when planning endovascular treatment and may have an influence on functional outcomes. More research into endovascular techniques and the risks of periprocedural complications must be performed. Indeed, a homogeneous protocol for the assessment of surviving VGAM patients during follow-up is necessary.

Progress in application of medical absorbable haemostatic materials for haemostasis in orthopaedic surgery

The application progress of medical absorbable haemostatic material (MAHM) in hemostasis during orthoapedic surgery was reviewed, in order to provide reference for clinical hemostasis program. The domestic and foreign literature on the application of MAHM for hemostasis in orthopedic surgery was extensively reviewed and summarized. According to biocompatibility, MAHM can be divided into oxidized cellulose/oxidized regenerated cellulose materials, chitosan and its derivatives materials, starch materials, collagen and gelatin materials, and fibrin glue materials, etc., which can effectively reduce blood loss when used in orthopedic surgery for hemostasis. Each hemostatic material has different coagulation mechanism and suitable population. Oxidized cellulose/oxidized regenerated cellulose, chitosan and its derivatives, starch hemostatic material mainly stops bleeding by stimulating blood vessel contraction and gathering blood cells, which is suitable for people with abnormal coagulation function. Collagen, gelatin and fibrin glue hemostatic materials mainly affect the physiological coagulation mechanism of the human body to stop bleeding, suitable for people with normal coagulation function. Reasonable selection of MAHM can effectively reduce perioperative blood loss and reduce the risk of postoperative complications, but at present, single hemostatic material can not meet clinical needs, and a new composite hemostatic material with higher hemostatic efficiency needs to be developed.

MATERIAL INVENTORY INFORMATION SYSTEM AT UD. ALAM RAYA WEB-BASED USING THE WATERFALL METHOD

UD. Alam Raya is a trading business engaged in the sale of building materials. UD. Alam Raya provides various types of building materials such as wood, nails, cement, iron, electrical tools, pipes, glue, and other building materials. In processing inventory and finances are still not computerized. Recording of sales transactions and purchases of goods is still done manually on notes and large sheets of paper grouped by transaction date. Recording on paper media is less effective because when the paper is exposed to water, the writing on it also fades, hindering the process of making financial reports. Based on these problems, a computerized building material inventory information system is needed in order to facilitate sales and purchase data processing as well as financial reports at UD. universe. This study uses qualitative research methods and the waterfall software development method, as well as the PHP (Hypertext Preprocessor) programming language using the CodeIgniter framework. This research succeeded in designing and creating a building material inventory information system at UD. universe. The benefit of this building material inventory information system is that it makes it easier to make purchase reports, sales reports, and financial reports at UD. universe

Preventing water-inrush from floor in coal working face with paste-like backfill technology

In the view of the situation where great economic loss often occurs during mining deep coal seams in Feicheng coal field due to water inrush from the floor Ordovician limestone aquifer, the floor "lower four-zone" theory was used as a guide. 81006 working face of Caozhuang Coalmine in Feicheng coal field was taken as the research background, and paste filling technology was proposed to inhibit or reduce the damaged floor depth caused by mine ground pressure in order to prevent water inrush from the floor Ordovician limestone aquifer. Glue material, coal gangue powder, and fly ash were selected as filling material, and a ground filling system, including a material production system, storage material system, power supply and water supply system, automatic control and measurement system, monitoring and control communications system, emergency response system, and underground filling system, including pipe conveyor system and working face blocking grout loss system, were established to achieve effective filling goaf. Field stress monitoring and floor damaged depth measurement showed that when reaching a steady state after a period of time, paste filling working face not only restored to the original stress state but also significantly reduced the floor's damaged depth caused by mine ground pressure. This verifies that working face with paste-like backfill technology is a very effective measure to prevent water-inrush from the floor.

Sensing Performance of Ethanol Microfiber Probe Augmented by ZnO Nanosheet and UV Glue Film

A microfiber reflective ethanol gas sensing probe was designed and fabricated. The single-mode fiber was heated and stretched to prepare a microfiber taper, on which a mixed material of ZnO nanosheets and UV glue was built by the dip-coating method. The influencing factors on its sensing performance for ethanol have been discussed, including the dozen ratio of ZnO nanosheets, UV glue materials, and end-face morphology. As the concentration of ethanol gas increased, the intensity of the reflection spectrum increased with the responding sensitivity of 7.28 × 10−4 dBm/ppm. The exchanging efficiency of the optical signal is enhanced by the strong evanescent field of the microfiber taper. This sensing probe is convenient for high-density integration and working in a small space and is capable of high-performance monitoring for ethanol at room temperature.

CELLULOSE NANOFIBRES REINFORCED INJECTABLE HYDROGELS AS ARTIFICIAL FIBRIN GLUE FOR TISSUE ENGINEERING

Currently, fibrin glue obtained from fibrinogen and thrombin of human and animal blood are widely investigated to use as injectable hydrogel for tissue engineering which contributes to minimally invasive surgery, superior biodegradability, cell attachment, proliferation and regenerating new tissue. However, most of them fail to achieve to be used for tissue engineering application because of a risk of immune response and poor mechanical properties. To overcome the limitation of fibrin glue and to reduce the usage of products from human and animal blood, the artificial fibrin glue materials were developed. Recently, cellulose nanofiber (CNF) as reinforcing agent has been explored for many tissue engineering applications such as bone and cartilage due to its impressive biological compatibility, biodegradability and mechanical properties. CNF was extracted from cassava pulp. PEO-PPO-PEO diacrylate block copolymer is a biodegradable synthetic polymers which is water insoluble hydrogel after curing by UV light at low intensity. To enhance the cell adhesion abilities, gelatin methacrylate (GelMA), the denature form of collagen was used to incorporate into hydrogel. The aim of this study was to develop the artificial fibrin glue from CNF reinforced PEO-PPO-PEO diacrylate block copolymer/GelMA injectable hydrogel.CNF/PEO-PPO-PEO diacrylate block copolymer/GelMA injectable hydrogels were prepared with 2-hydroxy-1-(4-(hydroxy ethoxy) phenyl)-2-methyl-1-propanone (Irgacure 2959) as a photoinitiator. The physicochemical properties were investigated by measuring various properties such as thickness, gel fraction, mechanical properties and water uptake.At optimal preparation condition, CNF reinforced injectable hydrogel was successful prepared after curing with UV light within 7 minutes. This hydrogel showed gel fraction and water uptake of 81 and 85%, respectively. The cytotoxicity, cell adhesion and proliferation of CNF reinforced injectable hydrogel was presented.Cellulose nanofiber from casava pulp was successfully used to prepare injectable hydrogel as artificial fibrin glue for tissue engineering. The hydrogel showed good physical properties which can be applied to use for tissue engineering application.

Abstract Number ‐ 110: Case Report of Glue Embolism Complication after Lingual Artery Embolization and Rescue Thrombectomy

Introduction 68‐year‐old right‐handed female with right tongue‐base squamous cell carcinoma status‐post wide surgical‐excision and flap reconstruction, whopresented with large volume right‐sided orolingual hemorrhage. Due to concerns of impending airway compromise and a history of difficult intubation, Interventional Neuroradiology was consulted to perform an angiogram and embolization. Methods A 6FrEnvoy was advanced into the external carotid artery and the origin of the lingual artery. Despite repeated attempts using a variety of microsystems, distal access within the lingual artery could not be achieved (Fig. 1B). N‐butyl‐2‐cyanoacrylate was prepared and injected with adequate penetration. Negative pressure was applied to the microcatheter and withdrawn. The guide catheter was aspirated and rapidly withdrawn under negative pressure. A control angiogram was being prepared when an intracranial glue cast was seen and confirmed to be a proximal M2‐occlusion. 4000U of Heparin werebolusedat this time. An Advantage Exchange wire facilitated an exchange for an 8Fr groin sheath and a Walrus catheter. The glue was crossed with a microsystem microsystem and a Solitaire‐4×40mm was deployed. A ZOOM55 was advanced to the face of the glue caste and together these were pulled into the Walrus catheter. Serial angiograms revealed stenosis, but patency. Results Initial post‐thrombectomy exam revealed mild left‐hand paresis. However, the patient’s neurologic status declined and progressed to left arm hemiparesis, facial droop, and right gaze‐preference. An angiogram was performed, which revealed re‐occlusion of the left M2 trunk. Using aTrevo‐3×32mmstentriever, the M2‐occlusion was recanalized with persistent stenosis. Serial angiograms were concerning for progressing re‐occlusion. The patient improved with residual distal left hemiparesis. Conclusions •Distal access may be extremely difficult in select cases. The proximal location of the microcatheter relative to the origin of the lingual artery and the external carotid artery off the common carotid artery, likely contributed to the embolic event. The use of progressively smaller microcatheters to facilitate distal access in turn biased the choice of embolization materials. Lastly, there was evidence of vasospasm in the lingual artery, which may have contributed to proximal polymerization and adherence to the catheters during their removal. •After successful retrieval of the glue material, there was residual stenosis of unclear etiology, possibly due to denuded endothelium, dissection, or residual glue promoting in‐situ thrombosis. The eventual clearing of thebolusedheparin may have contributed to the delayed re‐occlusion. Recanalization after re‐occlusion was only possible after thrombectomy. •The use of an intermediate catheter may mitigate the risk of glue embolization by facilitating distal access and/or by providing an additional conduit for aspirating refluxed glue. If distal access into a culprit vessel can not be achieved, coil embolization may be a safer choice. Re‐canalized glue embolisms may be prone to re‐occlusion. Continuing a heparin drip may be prudent practice to prevent re‐occlusion.

Macular holes – A review on surgical techniques and outcomes

Macular hole has been associated with myriad ocular conditions, the most common being Idiopathic Macular hole followed by Traumatic Macular Hole, Myopic Macular Hole and many more. The etiology of idiopathic macular holes remains unclear despite a huge number of studies. The surgical intervention in the management of Macular Holes has undergone huge modifications over a period. This review article aims to analyze various surgical techniques and their outcomes. Newer surgical techniques like modifications in ILM flap techniques, scaffolding of Autologous flap with various glue materials, MH surgery in various special situations have been discussed vividly in this article. Recent advances in the surgical management of MH and their visual improvement and closure rates have been discussed thoroughly.

Surgical Bone Adhesives with Potential Maxillofacial Applications A Systematic Review

The reduction and stabilisation of fractured bone fragments have always been a challenging task for thesurgeon. A micro-platesystem for maxillofacial fracture treatment provides excellent results. However, plates and screws are difficult toadapt to the thin bone, and small fragments often lead to the weakening of bone causing secondary fractures. Surgical bone adhesives promise as a viable alternative for issues with micro-plates, but a lotremains desired for successful usefor clinical application. The present systematic review aims to identify the bone adhesive materials available at various stages in animal or human models in the last decade and enumerate their characteristics for potential use in non-load bearing maxillofacial fractures. PubMed electronic database searched using a combination of keywords to identify English language articles between January 2011 and December 2020 yielded a total of 1204 records, of which 15 were included for final review after applying PRISMA guidelines. Cyanoacrylate was the commonly used adhesive material followed by fibrin glue and calcium phosphate-based materials. Although encouraging, results with each material still lack human randomised control trials thus presenting inconclusive evidence. Studies on these lines are suggested along with the development of newer materials to overcome the shortcomings in the currently available systems.

Looking to the future: Building New Paradigms in Comparative Physiology and Biomechanics

Looking to the future: Building New Paradigms in Comparative Physiology and Biomechanics

Influence of ANO&lt;sub&gt;3&lt;/sub&gt; and ANO&lt;sub&gt;3&lt;/sub&gt;·nH&lt;sub&gt;2&lt;/sub&gt;O Nitrates on the Deformation Properties of Aluminosilicate Adhesives for Wood Products and Structures

As a result of the research, the deformation properties of aluminosilicate adhesives modified with nitrate salts and intended for gluing wooden products and structures made of pine, beech and oak wood at different stages of their hardening were determined. Considering that pine is the most common wood in the manufacture of products and structures, then in order to reduce the numerical values of the elastic modulus in glued materials, it is advisable to add ammonium, lithium and sodium nitrates in an amount of 0.5%, potassium nitrate in an amount of 1% into the composition of an aluminosilicate adhesive. which will ensure the approximation of the elastic modulus values to the values of the unmodified aluminosilicate adhesive and will significantly affect the water resistance of the glue joint and the depth of penetration of the adhesive into the wood structure. For gluing beech wood products to reduce the elasticity modulus, it is advisable to introduce 0.5% ammonium and potassium nitrates and 1% lithium and sodium nitrates, which will reduce the numerical values of the elastic modulus in glued materials by 1.18 and 1.53 times compared with the values of the elastic modulus of the unmodified aluminosilicate adhesive. For gluing oak wood products to reduce the elasticity modulus, it is advisable to introduce 0.5% potassium nitrate and 1.5% sodium nitrate, which will reduce the numerical values of the elastic modulus in glued materials by 1.4 and 2.83 times compared to the values modulus of elasticity of unmodified aluminosilicate adhesive.

GaInP/GaAs/poly-Si Multi-Junction Solar Cells by in Metal Balls Bonding

In this study, a mechanical stacking technique has been used to bond together the GaInP/GaAs and poly-silicon (Si) solar wafers. A GaInP/GaAs/poly-Si triple-junction solar cell has mechanically stacked using a low-temperature bonding process which involves micro metal In balls on a metal line using a high-optical-transmission spin-coated glue material. Current–voltage measurements of the GaInP/GaAs/poly-Si triple-junction solar cells have carried out at room temperature both in the dark and under 1 sun with 100 mW/cm2 power density using a solar simulator. The GaInP/GaAs/poly-Si triple-junction solar cell has reached an efficiency of 24.5% with an open-circuit voltage of 2.68 V, a short-circuit current density of 12.39 mA/cm2, and a fill-factor of 73.8%. This study demonstrates a great potential for the low-temperature micro-metal-ball mechanical stacking technique to achieve high conversion efficiency for solar cells with three or more junctions.

Preclinical Testing of New Hydrogel Materials for Cartilage Repair: Overcoming Fixation Issues in a Large Animal Model.

Reinforced hydrogels represent a promising strategy for tissue engineering of articular cartilage. They can recreate mechanical and biological characteristics of native articular cartilage and promote cartilage regeneration in combination with mesenchymal stromal cells. One of the limitations of in vivo models for testing the outcome of tissue engineering approaches is implant fixation. The high mechanical stress within the knee joint, as well as the concave and convex cartilage surfaces, makes fixation of reinforced hydrogel challenging. Methods. Different fixation methods for full-thickness chondral defects in minipigs such as fibrin glue, BioGlue®, covering, and direct suturing of nonenforced and enforced constructs were compared. Because of insufficient fixation in chondral defects, superficial osteochondral defects in the femoral trochlea, as well as the femoral condyle, were examined using press-fit fixation. Two different hydrogels (starPEG and PAGE) were compared by 3D-micro-CT (μCT) analysis as well as histological analysis. Results. Our results showed fixation of below 50% for all methods in chondral defects. A superficial osteochondral defect of 1 mm depth was necessary for long-term fixation of a polycaprolactone (PCL)-reinforced hydrogel construct. Press-fit fixation seems to be adapted for a reliable fixation of 95% without confounding effects of glue or suture material. Despite the good integration of our constructs, especially in the starPEG group, visible bone lysis was detected in micro-CT analysis. There was no significant difference between the two hydrogels (starPEG and PAGE) and empty control defects regarding regeneration tissue and cell integration. However, in the starPEG group, more cell-containing hydrogel fragments were found within the defect area. Conclusion. Press-fit fixation in a superficial osteochondral defect in the medial trochlear groove of adult minipigs is a promising fixation method for reinforced hydrogels. To avoid bone lysis, future approaches should focus on multilayered constructs recreating the zonal cartilage as well as the calcified cartilage and the subchondral bone plate.

Прочность клеесварных соединений при длительном воздействии отрицательных температур

The experimental test results of strength of glued and glued-welded joints at room and negative temperatures after long exposure of them at –30 °С and –50 °С are presented. As glue materials, epoxy adhesive, anaerobic adhesive-sealant, silicone sealant and adhesive-melt based on copol-ymer of ethylene with vinyl acetate were used, as substrates, steel and aluminum alloy samples were used. It has been found out that silicone sealant ensures the best strength of glued-welded joints at low temperatures. It was determined that for all the studied types of the glued-welded joints, strength at –30 °С was worse than at –50 °С.

Protein morphology drives the structure and catalytic activity of bio-inorganic hybrids

Bio-hybrid materials have received a lot of attention in view of their bio-mimicking nature. One such biomimetic material with catalytic activity are the protein derived floral nanohybrid. Copper phosphate coordinated flakes can be curated to distinct floral morphology using proteins. Structurally two different proteins with similar size and with no known enzymatic activity are used to evaluate the role of protein structure and morphology, on the structure-activity relationship of the developed hybrid nanoflowers. Globular protein BSA and bacterial microcompartment domain protein PduBB′ are selected. PduBB′ because of self-assembling nature forms extended sheets, whereas BSA lacks specific assembly. The developed hybrid NFs differ in their morphology and also in their mimicry as a biological catalyst. The present investigation highlights the importance of the quaternary structure of proteins in tailoring the structure and function of the h-NFs. The results in this manuscript will motivate and guide designing, engineering and selection of glue material for fabricating biomacromolecule derived biohybrid material to mimic natural enzymes of potential industrial application.

Preparation and Characterization of Japanese Ink-Inspired Aqueous Dispersions of Carbon Materials with the Help of Glue as Colloid Chemistry Teaching Aid

Aqueous dispersions of soot and other carbon materials, prepared in a manner similar to that used for preparing traditional Japanese ink, were developed as teaching materials for colloid chemistry. The protective colloid formed by the addition of glue is an interesting teaching material that allows visual understanding of various colloidal phenomena. In addition, such dispersions can be prepared using glue and various carbon materials (e.g., pencil lead, barbecue charcoal, C60 fullerene, graphene, and carbon nanotubes), following an extremely simple and environmentally friendly method. The carbon materials are insoluble in water without the glue, highlighting the need for glue to act as a protective colloid in ink preparation. Herein, we describe convenient colloid chemistry experiments that are adaptable to a wide range of educational settings.

First record of Gastrallus laticollis pic 1929 (coleoptera: Bostrichoidea: Ptinidae) in Sri Lanka

Libraries, archives and museums in tropical countries like Sri Lanka are at great risk to be infested by insect pests. These can damage especially celluloses-based and starch glue materials and objects like books, paper or traditional palm leave manuscripts. Besides beetles (Coleoptera, mainly Ptinidae), also termites (Isoptera) and silverfish (Zygentoma) are the most problematic pests infesting these collections across the island. We sampled the pests and their abundance in the National Museum Library in Colombo and found six different species of library pests: the termite Cryptotermes sp., two silverfish species Lepisma saccharinum, Ctenolepisma longicaudatum and three beetle species of Ptinidae: Lasioderma serricorne, Stegobium paniceum and Gastrallus laticollis. G. laticollis is a new species to the fauna of Sri Lanka, it is only known from Singapore. Its occurrence in Sri Lanka and the distribution of other species of the genera Gastrallus in Asia are discussed.

Выбор режимов сварки при сборке различных материалов по клеесварной технологии

General requirements for change of welding conditions in case of the replacement of the welding tehnology by the glue-welding one have been examined. Conditions of making the glue-weld joints of different grades of steel and aluminum were determined. It was found out that the glue-welding technology required a decrease in the value of welding current and an increase in welding time and the compressive force value of electrodes. A selection of conditions depends on material of jointed components and do not depends on a type of glue material. The study results are presented.

Chronic rhinosinusitis due to cyano-acrylic glue after endoscopic transsphenoidal pituitary surgery

BackgroundTo reduce the risk of cerebrospinal fluid leak, clinicians utilize a filling material placed in the sella followed by floor reconstruction with various materials, including glue sealing. Cyano-acrylic glue Glubran®2 glue is commercially available and is generally used as embolizing agent and for the prevention of cerebrospinal fluid leakage.Case DescriptionA 25-year-old woman underwent endoscopic endonasal transsphenoidal surgery for pituitary adenoma. After tumor resection, sellar floor reconstruction was performed by mucosal graft and Glubran®2 glue. The early post-operative period was uneventful. However, 2 months after surgery, the patient complained of headache, facial pain and greenish foul-smelling nasal discharge with solid particles dripping from the nose. Medical treatment was unsuccessful. Brain MRI showed inflammation and thickening of the sphenoidal and para-sphenoidal mucosa. The patient underwent endoscopic endonasal surgery and a solid glass-like mass surrounded by inflamed infected mucosa was seen in the inferior and lateral aspects of the sphenoid sinus. Efforts were made to erupt and de-crust the solid mass until total resection was achieved. Early post-operative period was uneventful, and a course of antibiotics was continued until total disappearance of the discharge.ConclusionTo the best of our knowledge, this is the first case reporting of acrylic glue (Glubran®2)-related sinusitis. Surgeon should be aware about similar side effects for the glue material that would complicate the surgery.