Global Definition Research Articles

A self-made Zimbabwean musician: A case study of DIY culture in the global south

This article contributes to defining global south DIY music culture by evaluating the career of a Zimbabwean self-made musician, Clive Mono Mukundu. Therefore, it assesses how his career exhibits extant DIY culture traits and strategies while exploring challenges specific to the Zimbabwe music scene. I reviewed the musician's autobiography and conducted in-depth semi-structured interviews to collect the data I analyse using the DIY culture traits and strategies, presenting it as thick descriptions. The findings help to illustrate some of the distinctive qualities of southern DIY culture coupled with northern traits and strategies. Hence, there is a need for specific global south DIY culture definitions inclusive of traits and strategies. The article recommends inclusivity through promoting global south participation in creative economy debates and argues for replication of this research to avoid overgeneralising its findings and help to establish a broader picture of southern DIY culture and music scenes.

Subclinical and clinical acute kidney injury share similar urinary peptide signatures and prognosis.

Acute kidney injury (AKI) is a frequent and severe condition in intensive care units (ICUs). In 2020, the Acute Dialysis Quality Initiative (ADQI) group proposed a new stage of AKI, referred to as stage 1S, which represents subclinical disease (sAKI) defined as a positive biomarker but no increase in serum creatinine (sCr). This study aimed to determine and compare the urinary peptide signature of sAKI as defined by biomarkers. This is an ancillary analysis of the prospective, observational, multinational FROG-ICU cohort study. AKI was defined according to the Kidney Disease Improving Global Outcome definition (AKIKDIGO). sAKI was defined based on the levels of the following biomarkers, which exceeded the median value: neutrophil gelatinase-associated lipocalin (pNGAL, uNGAL), cystatin C (pCysC, uCysC), proenkephalin A 119-159 (pPENKID) and liver fatty acid binding protein (uLFABP). Urinary peptidomics analysis was performed using capillary electrophoresis-mass spectrometry. Samples were collected at the time of study inclusion. One thousand eight hundred eighty-five patients had all biomarkers measured at inclusion, which included 1154 patients without AKI (non-AKIKDIGO subgroup). The non-AKIKDIGO subgroup consisted of individuals at a median age of 60 years [48, 71], among whom 321 (27.8%) died. The urinary peptide signatures of sAKI, regardless of the biomarkers used for its definition, were similar to the urinary peptide signatures of AKIKDIGO (inflammation, haemolysis, and endothelial dysfunction). These signatures were also associated with 1-year mortality. Biomarker-defined sAKI is a common and severe condition observed in patients within intensive care units with a urinary peptide signature that is similar to that of AKI, along with a comparable prognosis.

Maturity levels of management process for improving industrial performance

In an increasingly varied and dynamic world, staying competitive and meeting the growing demands of customers and the market has become a real challenge for any company that strives for excellence. Therefore, adopting a performance management system is an essential decision to face unexpected market changes. Thus, the quality must be projected on the approaches and the practices mainly characterized by a high degree of maturity, which gives the company the ability to achieve continuous process improvements and meet the expressed and implicit needs of customers. However, other tools can help develop a sense of strong responsibility toward performance in its global definition and at all hierarchical levels of the company. The main contribution of this work is adapting a maturity model to assess management processes in manufacturing industries inspired by the "Capability Maturity Model Integration CMMI". In this work, a survey of Moroccan industries of different sizes operating in different sectors of activity is conducted, to define their maturity levels and their relationship with different types of industrial management.

Incidence of wound dehiscence in patients undergoing laparoscopy or laparotomy: a systematic review and meta-analysis.

Surgical wound dehiscence (SWD) is a serious complication-with a 40% estimated mortality rate-that occurs after surgical intervention. Since the implementation of advanced recovery protocols, the current global incidence of SWD is unknown. This systematic review and meta-analysis estimated the worldwide incidence of SWD and explored its associated factors in general surgical patients. Eligible full-text cross-sectional, cohort and observational studies in English, between 1 January 2010 to 23 April 2021, were retrieved from MEDLINE, CINAHL, EMBASE and the Cochrane Library. Data extraction and quality appraisal were undertaken independently by three reviewers. Random effects meta-analytic models were used in the presence of substantial inconsistency. Subgroup, meta-regression and sensitivity analyses were used to explore inconsistency. Publication bias was assessed using Hunter's plots and Egger's regression test. Of 2862 publications retrieved, 27 studies were included in the final analyses. Pooled data from 741,118 patients across 24 studies were meta-analysed. The 30-day cumulative incidence of SWD was 1% (95% Confidence Interval (CI): 1-1%). SWD incidence was highest in hepatobiliary surgery, at 3% (95% CI: 0-8%). Multivariable meta-regression showed SWD was significantly associated with duration of operation and reoperation (F=7.93 (2-10); p=0.009), explaining 58.2% of the variance. Most studies were retrospective, predated the agreed global definition for SWD and measured as a secondary outcome; thus, our results likely underestimate the scope of the problem. Wider uptake of the global definition will inform the SWD surveillance and improve the accuracy of reporting.

Social workers’ intention to hold elected political office: a quantitative study based on the theory of planned behavior

ABSTRACT Social work is closely intertwined with formal and informal policy processes and social workers, in line with the global definition of social work as well as national codes of ethics, are called upon to act as policy actors at various levels. One possible way to do this is to hold elected political office. This quantitative cross-sectional study examines the intention of 92 Swiss social workers to hold elected political office at the local, cantonal, or national level and uses the Theory of Planned Behavior (TPB) to identify factors associated with their intention. The findings show that social workers’ intention is strongly associated with the core factors of the TPB – attitudes, subjective norm, and perceived behavioural control. Based on the study’s findings, this article outlines avenues for further research and suggests possible strategies to enhance the policy role of social workers, specifically addressing social work education, professional associations of social work, and social welfare organisations.

A New Global Definition of Acute Respiratory Distress Syndrome.

Background: Since publication of the 2012 Berlin definition of acute respiratory distress syndrome (ARDS), several developments have supported the need for an expansion of the definition, including the use of high-flow nasal oxygen, the expansion of the use of pulse oximetry in place of arterial blood gases, the use of ultrasound for chest imaging, and the need for applicability in resource-limited settings. Methods: A consensus conference of 32 critical care ARDS experts was convened, had six virtual meetings (June 2021 to March 2022), and subsequently obtained input from members of several critical care societies. The goal was to develop a definition that would 1) identify patients with the currently accepted conceptual framework for ARDS, 2) facilitate rapid ARDS diagnosis for clinical care and research, 3) be applicable in resource-limited settings, 4) be useful for testing specific therapies, and 5) be practical for communication to patients and caregivers. Results: The committee made four main recommendations: 1) include high-flow nasal oxygen with a minimum flow rate of ⩾30 L/min; 2) use PaO2:FiO2 ⩽ 300 mm Hg or oxygen saturation as measured by pulse oximetry SpO2:FiO2 ⩽ 315 (if oxygen saturation as measured by pulse oximetry is ⩽97%) to identify hypoxemia; 3) retain bilateral opacities for imaging criteria but add ultrasound as an imaging modality, especially in resource-limited areas; and 4) in resource-limited settings, do not require positive end-expiratory pressure, oxygen flow rate, or specific respiratory support devices. Conclusions: We propose a new global definition of ARDS that builds on the Berlin definition. The recommendations also identify areas for future research, including the need for prospective assessments of the feasibility, reliability, and prognostic validity of the proposed global definition.

Język w czasach globalizacji/ Language in the age of globalization

The article focuses on the relationship between globalization and language in the modern world. In the theoretical part of the paper the author explains the concepts of globalization and westernization before discussing the definition of the lexeme globalization in English, Polish and Russian. In the practical part, such words as mall, strip mall, food hall, food mall, food court, droguerie, discount store are analyzed. Assimilation processes and the registration of new lexis in dictionary sources (are used to) demonstrate the mechanism of the impact of progressing globalization processes on the language – the gradual transition from foreign realities and an unknown word to the assimilation of these realities together with the names. The dynamic changes in the language system are caused by the dynamic changes that the modern world is undergoing. The analysis is conducted on material from English, Polish, Russian and – partly – Ukrainian.

1003-P: Cost of Care for Patients with Diabetic Kidney Disease in Veterans Health Administration

Introduction: Diabetic kidney disease (DKD) represents a substantial burden on the Veterans Health Administration (VHA). We calculated the cost of DKD care for US Veterans from the healthcare system perspective. Methods: Veterans with type 2 diabetes (T2D) in 2015-2021 were identified using diagnosis codes, prescription records, and problem lists. We identified prevalent and incident DKD stages based on urine albumin, urine protein, and eGFR, and following the Kidney Disease Improving Global Outcome definitions. Aggregate all-cause monthly healthcare costs per patient for managing each DKD stage (ie, stages 1 through 5) were estimated by summing patient-level VHA costs in incident DKD stages from January 2018 until December 2021. Summary statistics include descriptive median and interquartile ranges of per-patient per-month [PPPM] cost. All costs were inflated to 2022 US dollars (USD) based on the Consumer Price Index of all items for urban consumers. Results and Conclusion: Out of two million US Veterans with T2D, we identified 401,214 DKD patients with 1+ incident stage progression in the follow-up period. Median PPPM all-cause healthcare cost increased exponentially from $748 at Stage 1 to $2,661 at Stage 5 (Figure). Interventions targeting patients with rapid DKD progression could markedly decrease the burden of DKD in US Veterans. Disclosure K.Kim: Research Support; Renalytix, GRAIL (acquired by Illumina in 2021), AstraZeneca. J.L.Crook: None. C.S.Lu: None. R.E.Nelson: None. H.Nyman: None. J.Lafleur: Research Support; Renalytix, Genentech, Inc., Novartis Pharmaceuticals Corporation.

The Loop Momentum Amplituhedron

In this paper we focus on scattering amplitudes in maximally supersymmetric Yang-Mills theory and define a long sought-after geometry, the loop momentum amplituhedron, which we conjecture to encode tree and (the integrands of) loop amplitudes in spinor helicity variables. Motivated by the structure of amplitude singularities, we define an extended positive space, which enhances the Grassmannian space featuring at tree level, and a map which associates to each of its points tree-level kinematic variables and loop momenta. The image of this map is the loop momentum amplituhedron. Importantly, our formulation provides a global definition of the loop momenta. We conjecture that for all multiplicities and helicity sectors, there exists a canonical logarithmic differential form defined on this space, and provide its explicit form in a few examples.

Social work disaster practice

INTRODUCTION: Natural and human-made disasters, including climate change, pandemics, and other hazards such as earthquake and flooding can have considerable negative impact on all communities in Aotearoa New Zealand. This article uses a case study approach to describe the experiences and reflections of social workers in relation to disaster practice. METHODS: This phase of the research project included semi-structured interviews with 11 registered social workers who had been involved in disaster management in Aotearoa New Zealand. The case studies were examined using thematic analysis to identify key themes. This article draws on four of the 11 interviews grouped together after thematic analysis, enabling detailed exploration of experiences. FINDINGS: Analysis of the interviews identified that the transferable skills and knowledge of social workers are important for disaster practice; social workers are effective in connecting with individuals and communities; and improved professional relationships, systems, and processes are required so that the community is better supported following future disaster events. IMPLICATIONS: Social workers practise locally but are situated within an international context that is underpinned by global definitions, agendas, and goals. These, and local codes and standards, offer a rationale and framework for effective social work disaster practice. Stronger connection between the social work profession and the national emergency management organisation in Aotearoa New Zealand will build social capital and signal the profession’s commitment to community resilience in the context of disaster practice.

Impact of Globalization on African Culture

The process of globalization is inevitable because it is part of human nature. Man by nature is a social being with an irresistible urge to associate with his fellow human beings. Man cannot survive without associating with his fellow human beings. Globalization is a manifestation of this natural urge in man to associate with his fellow human beings and it is irresistible. I understand globalization to mean the process by which mankind gets closer together. This process has in recent times been facilitated by modern means of communication and transportation. Tremendous progress was made in this direction in the 20th century by the unprecedented advancement in the means of transportation and communication, e.g. Satellite and E-mail. This has turned the world to “global village”. You could have your dinner in Lagos and your breakfast the following morning in London. Through CNN, you could see and know what is happening in other part of the world. And through improved telecommunication, you could talk with anybody in other parts of the world. Through all these advancements in transportation and telecommunication, mankind is fast coming together, getting to know more about one another, becoming more and more interested and involved in what goes on in other parts of the world. Despite its numerous advantages, globalization has serious effects on African culture. It affects almost if not all aspects of African culture. One of such is the loss of one’s cultural identity and even national identity. The paper discusses meaning and definitions of culture, characteristics of culture, Categories and types of culture, meaning and definition of globalization, features of globalization, advantages of globalization and the impacts of globalization on African culture. The paper therefore concludes that globalization is good, but we must embrace it with caution and guard against the dangers inherent in it so that our cultural heritage is not eroded and sacrificed on the altar of globalization.

Effect of angiography timing on acute kidney injury after cardiac surgery in patients with preoperative renal dysfunction

BackgroundCardiac surgery-associated acute kidney injury (AKI) is one of the common complications of cardiac surgery. Preoperative angiography helps assess heart disease but may increase the risk of AKI. Although more and more patients with preoperative renal dysfunction can undergo cardiac surgery with the advances in surgical techniques, there is little research on the effect of angiography on postoperative AKI in these patients. This study investigates whether angiography increases the risk of AKI after cardiac surgery in patients with preoperative renal dysfunction (15 ≤ eGFR < 60 ml/min/1.73m2).MethodsPatients with preoperative renal dysfunction (15 ≤ eGFR < 60 ml/min/1.73m2) who underwent angiography and cardiac surgery successively from January 2015 to December 2020 were retrospectively enrolled in this study. The primary outcome was postoperative AKI, defined as the Kidney Disease: Improving Global Outcomes Definition and Staging (KDIGO) criteria. Univariate analysis and multivariate regression were performed to identify the association between angiography timing and AKI.ResultsA total of 888 consecutive eligible patients with preoperative renal dysfunction (15 ≤ eGFR < 60 ml/min/1.73m2) were enrolled in this study. The incidence of AKI was 48.31%. Male (OR = 1.903), the interval between angiography and surgery (0-2d OR = 2.161; 3-6d OR = 3.291), cross-clamp duration (OR = 1.009), were identified as predictors for AKI. The interval between angiography and surgery was also associated with AKI in the patients with 15 ≤ eGFR < 30ml/min/1.73m2 (0-2d OR = 4.826; 3-6d OR = 5.252), 30 ≤ eGFR < 45 ml/min/1.73m2 (0-2d OR = 2.952; 3-6d OR = 3.677), but not associated with AKI in patients with 45 ≤ eGFR < 60 ml/min/1.73m2.ConclusionsIn patients with preoperative renal dysfunction, the interval between angiography and cardiac surgery (0-2d and 3-6d) was associated with AKI. For patients with poorer preoperative renal function, the interval between angiography and cardiac surgery is of great concern.

ECONOMIC GLOBALIZATION – DIMENSIONS AND HISTORICAL PERSPECTIVES

In this paper, we approach a chronological analysis of globalization from an economic dimension. We know this term of globalization has become increasingly used since the 1990s. The phenomenon of globalization as well as its effects are subject to many analyzes quantifying both the socio-economic advantages and disadvantages. However, far fewer have focused on a historical analysis of economic globalization. Starting from the definition of globalization - a process by which economies become more and more interconnected and interdependent – can we assert that globalization has its origins in the mists of history with the occurrence and development of the silk road? Although there are many opinions about when globalization began, we believe that based on the arguments presented in this research, the trade routes created during the Silk Road represent an important moment in the history and beginnings of globalization. Throughout history, socio-economic events such as the first industrial revolution and the current digital revolution have led to the evolution of trade routes and the emergence of new technologies that have transformed the nature of trade.

Early Recurrence after Upfront Surgery for Pancreatic Ductal Adenocarcinoma.

Survival after surgery for pancreatic ductal adenocarcinoma (PDAC) remains poor, due to early recurrence (ER) of the disease. A global definition of ER is lacking and different cut-off values (6, 8, and 12 months) have been adopted. The aims of this study were to define the optimal cut-off for the definition of ER and predictive factors for ER. Recurrence was recorded for all consecutive patients undergoing upfront surgery for PDAC at our institute between 2010 and 2017. Receiver operating characteristic (ROC) curves were utilized, to estimate the optimal cut-off for the definition of ER as a predictive factor for poor post-progression survival (PPS). To identify predictive factors of ER, univariable and multivariable logistic regression models were used. Three hundred and fifty one cases were retrospectively evaluated. The recurrence rate was 76.9%. ER rates were 29.0%, 37.6%, and 47.6%, when adopting 6, 8, and 12 months as cut-offs, respectively. A significant difference in median PPS was only shown between ER and late recurrence using 12 months as cut-off (p = 0.005). In the multivariate analysis, a pre-operative value of CA 19-9 > 70.5 UI/L (OR 3.10 (1.41-6.81); p = 0.005) and the omission of adjuvant treatment (OR 0.18 (0.08-0.41); p < 0.001) were significant predictive factors of ER. A twelve-months cut-off should be adopted for the definition of ER. Almost 50% of upfront-resected patients presented ER, and it significantly affected the prognosis. A high preoperative value of CA 19-9 and the omission of adjuvant treatment were the only predictive factors for ER.

For a New International Public History

Proposed in the United States of America in the 1970s, the term “public history” is now used in various parts of the world. The internationalization of the field of public history raises various questions about its definition, its practices, and its theories. Based on sometimes long-established practices, public history reflects new approaches to audiences, collaboration and authority in history production. The article distinguishes and analyses the different phases of internationalization in the 1970s, 1990s, and 2010s and argues for a new international public history. Instead of a spread of public history, the new internationalization lies upon multicultural approaches and understandings of the field. Symbolized by the rise of public history in Italy, the glocal process of defining and practicing public history – where the local practices and theories relate and influence global definitions – provides more nuanced and richer understandings of the field. The new internationalization has concrete consequences on the public history structures, resources, languages, and projects.

Glocalizing creative hub concept for malaysian creative city development: A conceptual review

The creative hub concept is gaining popularity globally as a tool within the creative economy to generate socio-economic and cultural values for societal and community development. Though the concept is nascent and the creative hub itself can be manifested in variegated forms, the notion is oftentimes linked to urban development particularly the way creative hubs are found to be subsumed and contribute towards the growth of creative industries en route the formation of a creative city. Against this backdrop, this paper aims to explore the creative hub concept and the way this global concept it is being understood, adopted and adapted locally amidst Malaysian local nuances. Based on secondary data sources, a systematic literature review was conducted to review global definitions, concepts, examples and illustrate how creative hubs are linked to creative city development and sustainable urban development. Literature review based on similar themes for the Malaysian context showed that the creative hub concept is also variegated, and each hub is shaped by the initiators, funding model and formation purpose of either commercial, social or culture and artistic. The paper concludes that reconceptualization of Malaysian creative hubs is timely and apt by taking into consideration also elements like location, culture-specificity and the influence of ICT as the creative hub concept, its form and operations morph and navigate in response to the current global COVID-19 pandemic. The implications that derive from this study will have conceptual, practical and policy implications when adopting and adapting the creative hub concept for the Malaysian context. Keywords: Creative cities, creative hubs, concept, Malaysia

Defined daily doses in pediatric dosing- a theoretical example.

A defined daily dose for children (cDDD) taking body weight into account, was proposed as a better measure of drug utilization in children than the World Health Organization's DDD. There is no global definition of DDDs for children, and it is unclear which standard doses should be used for children when conducting drug utilization studies. We used doses according to the authorized medical product information and body weight according to national pediatric growth curves to calculate theoretical cDDD for three common medicines in children in a Swedish setting. These examples demonstrate that the concept of cDDD may not be optimal for drug utilization studies in children, especially not for younger children and when dosing is done according to weight is crucial. Validation of cDDD in real-world data is warranted. When conducting pediatric drug utilization studies, accessibility to individual-level data on body weight and age combined with dosing information is needed.

Malnutrition in Patients With Moderate to Severe Acquired Brain Injury: Prevalence During 4 Weeks of Subacute Rehabilitation.

BACKGROUND: Malnutrition is associated with high rates of complication, longer hospital stays, and increased morbidity and mortality. Malnutrition defined as undernutrition is common in patients with acquired brain injury (ABI); however, estimates vary remarkably. This study aimed to describe malnutrition at admission and after 4 weeks of subacute inpatient neurorehabilitation in patients with ABI using the new global consensus definition of malnutrition. METHODS: One hundred thirty-three patients with moderate to severe ABI consecutively admitted to a specialized neurorehabilitation hospital within a period of 4 months were screened for inclusion, of which 92 were included. Malnutrition was defined as at least 1 phenotypic criterion (weight loss, low body mass index, low muscle mass) and at least 1 etiologic criterion (reduced food intake, inflammation). Malnutrition on admission and after 4 weeks was compared using the McNemar test. RESULTS: The proportion of patients with malnutrition at admission was 42%, with more men (46%) than women (36%) fulfilling the criteria for malnutrition. The most frequent phenotypic and etiologic criteria were weight loss (56%) and inflammation (74%), respectively. During the 4 weeks of rehabilitation, the proportion of male patients fulfilling the individual criteria "weight loss" (difference, -21.4%) and "inflammation" (difference, -18.9%) decreased significantly; "low muscle mass" decreased borderline significant (difference, -8.9%), whereas "low body mass index" did not change. The proportion of female patients fulfilling individual criteria for malnutrition was stable or increased nonsignificantly. CONCLUSION: Malnutrition was common at admission to neurorehabilitation in patients with moderate to severe ABI, with more men than women fulfilling the criteria for malnutrition. The nutritional status improved after 4 weeks of rehabilitation in male patients, whereas it was largely unchanged in female patients. The results provide the basis for monitoring high-quality nutritional nursing care.

Association of early postoperative serum magnesium with acute kidney injury after cardiac surgery

Introduction Dysmagnesemia has been demonstrated to be involved in the pathophysiology of kidney diseases and is common in cardiac surgical patients. It remains unknown whether changes of serum magnesium after cardiac surgery affect AKI. We aimed to investigate the association of early postoperative magnesium with cardiac surgery-associated AKI in adults. Methods We conducted a multicenter retrospective cohort study involving patients who underwent cardiac surgery in the eICU Collaborative Research Database between 2014 and 2015. AKI within 7 days after surgery was defined using both serum creatinine and urine output criteria of Kidney Disease Improving Global Outcomes definition. Postoperative AKI was analyzed using multivariable logistic regression with early postoperative serum magnesium measured within the first 24 h after surgery as a continuous variable and categorically by quartiles. Results Postoperative AKI was identified in 3498 of 6124 (57.1%) patients receiving cardiac surgery. The median (25th–75th percentiles) early postoperative serum magnesium level of the study population was 2.3 (2.0–2.7) mg/dL. Higher serum magnesium level was associated with a higher risk of developing postoperative AKI (adjusted odds ratio (OR), 1.46 per 1 mg/dL increase; 95% confidence interval (CI), 1.31–1.62; p<.001). The multivariable-adjusted ORs (95% CIs) of postoperative AKI across increasing quartiles of serum magnesium were 1.00 (referent), 1.11 (0.95–1.29), 1.30 (1.12–1.52), and 1.72 (1.47–2.02) (p for trend <.001). Conclusions These data demonstrate a significantly higher incidence of AKI in patients with higher early postoperative serum magnesium who underwent cardiac surgery.

REDEFINISI PETANI: DISKURSUS INDONESIA VIS-A-VIS BARAT

In Indonesia, the rising rate of agricultural land conversion and soil degradation, decreasing agricultural exchange rates, advancing technological and cultural development, and expanding innovations in planting mediums and farming approaches, have blurred the definition of a peasant. Does the same phenomenon happen worldwide? This paper aims to set the evolution of the definition of a peasant in Indonesia globally. This study departed from the constructivism paradigm, which used a hermeneutics approach and literature study method. More than 50 literature from the past century were studied. We found that in Indonesia, the definition of the peasant has not been strongly justified from many perspectives (experts, institutions, communities), which created disparities in space and time contexts. While peasant’s global definition tends to be constant as it acts as the centre of the proposition just like other professions. Diversities in commodities, planting systems, and the bargaining position of farming as economic activity caused the specification of peasant’s definition in Indonesia. Thus, the definition of the peasant is still “wild” without strong boundaries. As one of the former colonial countries, Indonesia cannot be separated from its colonial inheritance, which affected the media and corporations. We conclude that the reconstruction of peasants’ definitions and praxis becomes a necessity because the biases of the paradigm and characteristics of peasants have made peasants lose their autonomy, sustainability and sense of humanity (humanism). The definition of peasant is not limited to space and land occupied, it has not been agreed upon as a profession and the label is used openly.