Glass façades are being increasingly applied in the typology of office buildings. The environmental quality parameters of indoor spaces have an exceptional influence on the wellbeing and productivity of users. In the past, climate defined the architecture of a particular area. Façades of contemporary office buildings have similar characteristics regardless of their location. This study comprises four office buildings with different types of glass façades located in areas of continental and coastal climate in Croatia. Also, the research relates to a graduate study course, during which the students designed a survey to gain insight into the satisfaction of users of the analyzed buildings. The aim of this research is to explore the impact of the design of glass façades in a certain climate context on users. This paper will address the following research questions: (1) Is a fully glazed office building pleasant to work in? (2) Is a fully glazed façade an appropriate solution for office buildings in hot and sunny climates? The research results show that to achieve a comfortable indoor environment for buildings’ users, it is necessary to design the façade according to the orientation, especially in terms of glazing characteristics, a sun protection system, and window control.