Glass Microspheres Research Articles

Experimentally characterising the temperature and rate dependent behaviour of unfilled, and glass microsphere filled, natural rubber

Low-impedance, elastomeric materials are widely used in engineering applications where they are subjected to impact loading leading to high strain rate deformation. The strong rate and temperature dependence that is exhibited by these polymers and their composites provides further motivation for a deeper understanding of this complex behaviour including the interaction between the matrix and filler materials. In this paper, unfilled and glass microsphere filled natural rubbers are used as model materials to better understand the behaviour of low-impedance particulate composites. These materials were characterised experimentally over a range of strain rates and temperatures. The effect of filler volume fraction and mean particle diameter on the rate and temperature dependence of the overall mechanical response was also investigated, as well as damage evolution based on post-deformation analysis of interrupted compression experiments. In this paper, experimental insights and data are presented and discussed, which will influence future constitutive modelling efforts.

Polymer composite microspheres loading 177Lu radionuclide for interventional radioembolization therapy and real-time SPECT imaging of hepatic cancer

BackgroundTransarterial radioembolization (TARE) with 90Y-labeled glass and resin microspheres is one of the primary treatment strategies for advanced-stage primary and metastatic hepatocellular carcinoma (HCC). However, difficulties of real-time monitoring post administration and embolic hypoxia influence treatment prognosis. In this study, we developed a new biodegradable polymer microsphere that can simultaneously load 177Lu and MgO nanoparticle, and evaluated the TARE therapeutic efficacy and biosafety of 177Lu-PDA-CS-MgO microspheres for HCC treatment.MethodsChitosan microspheres were synthesized through emulsification crosslink reaction and then conducted surface modification with polydopamine (PDA). The 177Lu and nano MgO were conjugated to microspheres using active chemical groups of PDA. The characteristics of radionuclide loading efficiency, biodegradability, blood compatibility, and anti-tumor effectwere evaluated both in vitro and in vivo. SPECT/CT imaging was performed to monitor bio-distribution and bio-stability of 177Lu-PDA-CS-MgO after TARE treatment. The survival duration of each rat was monitored. HE analysis, TUNEL analysis, immunohistochemical analysis, and western blot analysis were conducted to explore the anti-tumor effect and mechanism of composited microspheres. Body weight, liver function, blood routine examination were monitored at different time points to evaluate the bio-safety of microspheres.ResultsThe composite 177Lu-PDA-CS-MgO microsphere indicated satisfactory degradability, biocompatibility, radionuclide loading efficiency and radiochemical stability in vitro. Cellular evaluation showed that 177Lu-PDA-CS-MgO had significant anti-tumor effect and blocked tumor cell cycles in S phase. Surgical TARE treatment with 177Lu-PDA-CS-MgO significantly prolonged the medial survival time from 49 d to 105 d, and effectively inhibited primary tumor growth and small metastases spreading. Moreover, these microspheres indicated ideal in vivo stability and allowed real-time SPECT/CT monitoring for up to 8 weeks. Immunostaining and immunoblotting results also confirmed that 177Lu-PDA-CS-MgO had potential in suppressing tumor invasion and angiogenesis, and improved embolic hypoxia in HCC tissues. Further evaluations of body weight, blood test, and pathological analysis indicated good biosafety of 177Lu-PDA-CS-MgO microspheres in vivo.ConclusionOur study demonstrated that 177Lu-PDA-CS-MgO microsphere hold great potential as interventional brachytherapy candidate for HCC therapy.Graphical Polymer composite microspheres loading 177Lu radionuclide and MgO nanoparticles for interventional radioembolization therapy and real-time SPECT imaging of hepatic cancer.

Enhanced optical properties of glass microspheres using acid thermal integration - Brightness

The glass microspheres(GMSs) is widely used in reflective materials and road applications because of its high mechanical strength, adjustable refractive index and excellent retroreflective properties, so further improvement of the optical properties of GMS is still a current research hotspot. In this work, we prepare the high brightness GMSs using an acid-heat integrated method. The interior of GMSs consists of a silica-oxygen framework and cationic polymers, where a large amount of TiO2 increases the refractive index of GMSs, leading to the retrograde reflection behavior of light in GMSs. After leaching and heat-treatment, the change in surface state and the internal phase transition allow the GMSs to show superior optical properties. In particular, the brightness of GMSs increases from 39 cd*1x−1m−2 to 58 cd*1x−1m−2, and their optical performance meets the requirements for the use of 5G traffic road GMSs.

Double-sided functional infrared camouflage flexible composite fabric for thermal management

Irregular yttrium oxide nanopuncture-coated hollow glass microspheres (HGMs@Y2O3), as a lightweight, thermal insulating, and high IR reflectivity materials could be prepared by a simple hydrothermal and high-temperature calcination process. Here, a flexible composite fabric with sandwiched structure was designed to combine the good infrared camouflage performance with self-cleaning ability. Thereinto, aluminum foil (AF), HGMs@Y2O3, and polypropylene spunbond nonwoven fabric (PPF) were binded and applied for low emissivity layer, thermal insulating layer and self-cleaning layer, respectively. The flexible composite fabric can realize the infrared camouflage effect to effectively shield the heated object (62.8 °C). The radiation temperature detected by the infrared camera is only 32.4 °C, which had a reduction of 30.4 °C. Based on the functional fabrics (anti-fouling performance), excellent thermal insulation (K = 0.0908 W/m-K) and low infrared emissivity (Average emissivity (ε‾) of AF plane of composite <0.1; Average emissivity (ε‾) of PPF plane of composite <0.5), the composite material enables the choice of presenting antifouling or thermal camouflage properties in different environments. This work provides another insight into the fabrication of flexible infrared camouflage materials while facilitating the exploration of flexible infrared camouflage materials.

Water absorption in hollow glass microsphere composites under hydrostatic pressure: Mechanisms and influencing parameters

AbstractHollow glass microsphere composites, or syntactic foams, are widely used in marine environments due to their buoyancy. However, in service, loss of buoyancy occurs along time. This behavior is attributed to water absorption that leads to a mass increase of the material. This study investigates the water absorption of three types of syntactic foams under hydrostatic pressure with density ranging from 0.59 to 0.74 g. cm−3. Water absorption measurements are performed for a maximal duration of 3 years and under hydrostatic pressure up to 700 bars. Results show that water absorption is much higher than expected and attributed to the filling of microspheres that collapse over time. Based on results presented here, prediction of water absorption syntactic foams is proposed including the impact of applied hydrostatic pressure. This prediction allows estimating the buoyancy loss in hollow glass microsphere composite as a function of time, depth and sample size.

The ROWAN study: Safety and efficacy of transarterial radioembolization with Y-90 glass microspheres and the STRIDE regimen in hepatocellular carcinoma.

TPS622 Background: In patients with early and intermediate hepatocellular carcinoma (HCC) who are ineligible for resection, thermal ablation, or liver transplant, transarterial radioembolization (TARE) with yttrium-90 glass microspheres has shown superior efficacy compared to transarterial chemoembolization; a subset of patients progress despite effective local therapy. Immunotherapy using the single tremelimumab regular interval durvalumab (STRIDE) regimen has demonstrated superior overall survival to sorafenib in advanced HCC. Recent work showed that TARE upregulates both the innate and adaptive immune systems. The possibility for TARE and STRIDE to have additive or synergistic effects when combined is of current scientific and clinical interest. The primary objective of the Phase II ROWAN Study is to assess the objective response rate and durability of local tumor control with TARE followed by STRIDE vs. TARE alone. Methods: ROWAN is a global, open-label, prospective, multicenter randomized controlled trial comparing treatment with TARE using glass microspheres followed by the STRIDE regimen (a single dose of 300 mg tremelimumab combined with 1500 mg monthly dose of durvalumab for 18 months) to TARE alone in HCC. ROWAN will include 150 patients across approximately 20 study sites in North America and Europe. Key inclusion criteria: HCC, diagnosed by radiographic imaging or histology; ineligible for or declined liver resection, thermal ablation, or transplantation; Child-Pugh A; ECOG 0; life expectancy ≥6 months; treatment naïve; unilobar tumor; measurable by mRECIST; tumor volume ≤25% of whole liver volume; and untreated future liver remnant volume ≥30% of whole liver volume. Key exclusion criteria: extrahepatic metastases; shunt fraction with a lung dose of &gt;30 Gy; macrovascular invasion; infiltrative disease not evaluable by mRECIST; history of any organ allograph; autoimmune or inflammatory disorder; current use of immunosuppressive medication; history of malignancy other than HCC within past 3 years; and active infection. Patients will be randomized in a 1:1 ratio to two study arms (TARE followed by STRIDE or TARE alone) using two stratification factors (TARE treatment goal [ablative vs. non-ablative] and alpha fetoprotein level [&gt;400 vs. ≤400 ng/mL]). Tumor and blood samples will be collected for correlative studies. Co-primary efficacy endpoints are objective response rate and duration of response (localized mRECIST). The primary safety endpoint is the number of adverse events (AEs) and serious AEs. Interim statistical analyses will be conducted after 25 patients have been randomized to each arm and completed the second imaging assessment 6 months post-randomization; final analysis will be after the last evaluable patient has completed the 18 months follow-up visit post-randomization or discontinued treatment. Clinical trial information: 05063565 .

Microsphere A Novel Drug Delivery System – A Review

The microspheres are also called as micro-particles. Microspheres are characteristically spherical &amp; free flowing powders having particle size ranging from 1-1000μm consisting of proteins or synthetic polymers. Microsphere can be manufactured by various type of material such as glass, polymers, and ceramic microspheres Microspheres are used in drug delivery systems to overcome some of the problems of conventional therapy and enhance the therapeutic efficacy of a given drug they are designed. These delivery systems offer numerous advantages compared to conventional dosage forms, which include improved efficacy, reduced toxicity, improved patient compliance and convenience. At the target tissue the drug should deliver in an optimal amount in the right period of time with the minimum side effect &amp; maximum therapeutic effect, to get the desired effect. The microspheres received much attention not only for the prolonged release or controlled drug delivery to improve bioavailability, stability and action at the specific site to predetermined rate but also for targeting of the anticancer drugs to the tumour. Microspheres are various types like Bioadhesive microspheres, Magnetic microspheres, Floating microspheres, radioactive microspheres, Polymeric microspheres, Biodegradable polymeric microspheres, Synthetic polymeric microspheres. The microsphere are spherical microparticles &amp; are used where predictable &amp; consistent particle surface area is important. The microspheres has the drug located centrally within the particle where it is encased within the unique polymeric membrane. This review focuses on types, materials used, drawbacks, advantage &amp; disadvantage.

The EPOCH trial: Identifying key patient subgroups to optimize treatment planning.

130 Background: The primary objective of the original EPOCH trial was to evaluate the potential benefit of adding transarterial radioembolization (TARE) with yttrium-90 glass microspheres to second-line chemotherapy (chemo) versus chemo alone in patients with liver-dominant metastatic colorectal cancer (mCRC). Randomization was stratified by key prognostic factors, including KRAS status; however, it did not account for ECOG status and baseline CEA levels. We present post-hoc analyses investigating the impact of prognostic factors on primary and secondary endpoints to help optimize patient selection. Methods: EPOCH was a 1:1 randomized, open-label, global, multicenter Phase 3 trial. Primary endpoints were progression-free survival (PFS) and hepatic PFS (hPFS). Overall survival (OS) and time to deterioration of quality of life (TTDQOL) were secondary. Post-hoc analyses of the following subgroups were performed: Subgroup A (excluding patients with both ECOG=1 and CEA≥35ng/mL) and Subgroup B (patients with KRAS wild-type and either ECOG=0 or CEA&lt;35ng/mL). Kaplan-Meier analyses, hazard ratios (HRs) and log-rank tests were used to compare outcomes between TARE plus chemo and chemo only groups. Results: In Subgroup A, 160 (75.1%) patients were randomized to chemo only, versus 143 (66.5%) to the TARE arm. In Subgroup B, 91 (42.7%) patients were randomized to chemo only, versus 77 (35.8%) to the TARE arm. Results are shown for PFS, hPFS, OS, and TTDQOL in the intent-to-treat population. In both subgroups A and B, PFS, hPFS, and TTDQOL were significantly improved for the TARE plus chemo arm as compared to the chemo only arm; no OS difference was found. Conclusions: Careful patient selection using multiple prognostic factors is necessary to identify those who will benefit most from TARE with second-line chemo. Prognostic factors were important in identifying the level of benefit seen in patients treated with TARE and chemo versus chemo alone. Clinical trial information: NCT01483027 . [Table: see text]

Polyethyleneimine/polydopamine-functionalized self-floating microspheres for caramel adsorption: Interactions and phenomenological mass transfer kinetics

A polyethyleneimine/polydopamine-functionalized self-floating microsphere (EHGM/PDA/PEI) bears an etched hollow glass microsphere as a support, polydopamine as an interfacial cross-linking “glue”, and polyethyleneimine as a functional monomer was fabricated and used as a decolorization sorbent for sugarcane juice. The advantages of EHGM/PDA/PEI for sugarcane juice decolorization were attributed to its richness of target polyethyleneimine monomers, well-connected and abundant three-dimensional network-like aperture structure, and nontoxicity. Moreover, EHGM/PDA/PEI has excellent self-floating performance to allow separation from the adsorption system after decolorization and may have a faster separation speed and lower energy consumption than conventional solid–liquid separation methods. Synthetic caramels were used as model colorants of sugarcane juice to assess EHGM/PDA/PEI performance. The adsorption capacity of EHGM/PDA/PEI for caramels was 18.36 mg/g with a removal efficiency of 91.80% in the adsorption equilibrium state. The interaction mechanisms revealed that the caramel adsorption on EHGM/PDA/PEI was mostly mediated by protonated amine groups, followed by electron sharing. Two layers of caramels adhered onto EHGM/PDA/PEI were mainly mediated by electrovalent bonds between carboxylate and protonated amine. On average, one caramel molecule can be shared by 3–4 protonated amine groups of EHGM/PDA/PEI, which suggests a parallel sorption orientation. Four phenomenological mass transfer models [external diffusion resistance (EXTDR), internal diffusion resistance (INTDR), EXTDR–INTDR mixed, and adsorption onto active sites (AOAS)] proposed new and unique insights into the dynamic properties of the adsorption process.

Research on the Sound Insulation Performance of Composite Rubber Reinforced with Hollow Glass Microsphere Based on Acoustic Finite Element Simulation.

The composite rubber reinforced with hollow glass microsphere (HGM) was a promising composite material for noise reduction, and its sound insulation mechanism was studied based on an acoustic finite element simulation to gain the appropriate parameter with certain constraint conditions. The built simulation model included the air domain, polymer domain and inorganic particles domain. The sound insulation mechanism of the composite material was investigated through distributions of the sound pressure and sound pressure level. The influences of the parameters on the sound transmission loss (STL) were researched one by one, such as the densities of the composite rubber and HGM, the acoustic velocities in the polymer and inorganic particle, the frequency of the incident wave, the thickness of the sound insulator, and the diameter, volume ratio and hollow ratio of the HGM. The weighted STL with the 1/3 octave band was treated as the evaluation criterion to compare the sound insulation property with the various parameters. For the limited thicknesses of 1 mm, 2 mm, 3 mm and 4 mm, the corresponding optimal weighted STL of the composite material reached 14.02 dB, 19.88 dB, 22.838 dB and 25.27 dB with the selected parameters, which exhibited an excellent sound insulation performance and could promote the practical applications of the proposed composite rubber reinforced with HGM.

Reusable self-floating carriers recover heavy metals from industrial wastewater through heterogeneous nucleation for resource reuse

Coagulation-flocculation in industrial wastewater treatment drives environmental pollution from landfilling heavy metal-laden sludge. Efficient separation of the sludge is crucial for cost-effective metal recovery. This study explored a new separation method of Cu2+, Ni2+, Zn2+ and Cr3+ via self-floating metal hydroxides assisted by hollow glass microsphere (HGM) carriers. The amount of OH− was stoichiometric to the positive charges of metal ions, mixed with 1 mg mL−1 HGM, causing metal hydroxides to attach to HGM surface via heterogeneous nucleation. The self-floating system removed 37.5% and 14.0% more metals than sedimentation at 50 and 200 mg L−1 metal concentrations. HGM additions increased the particle size of metal hydroxides by up to 12.5 times to that of HGM at 18.8 ± 1.1 µm, benefiting their solid-liquid separation. By pumping the wastewater downward in column reactor at velocities equal to or less than the self-floating sludge, 96.4% metals were removed in continuous flow. The recovery rates of HGM and metals reached 92.0 ± 2.2% and 92.7 ± 3.2%, and the concentration of the recovered metal reached 19,339 ± 394 mg L−1 for potential reutilization in industrial electroplating. This research investigated a new separation strategy based on solid self-flotation for sustainable treatment of metal-laden wastewater.

Comprehensive Numerical Analysis of Temperature Sensitivity of Spherical Microresonators Based on Silica and Soft Glasses

In recent years, the use of optical methods for temperature measurements has been attracting increased attention. High-performance miniature sensors can be based on glass microspheres with whispering gallery modes (WGMs), as their resonant frequencies shift in response to the ambient parameter variations. In this work, we present a systematic comprehensive numerical analysis of temperature microsensors with a realistic design based on standard silica fibers, as well as commercially available special soft glass fibers (GeO2, tellurite, As2S3, and As2Se3). Possible experimental implementation and some practical recommendations are discussed in detail. We developed a realistic numerical model that takes into account the spectral and temperature dependence of basic glass characteristics in a wide parameter range. To the best of our knowledge, spherical temperature microsensors based on the majority of the considered glass fibers have been investigated for the first time. The highest sensitivity dλ/dT was obtained for the chalcogenide As2Se3 and As2S3 microspheres: for measurements at room temperature conditions at a wavelength of λ = 1.55 μm, it was as high as 57 pm/K and 36 pm/K, correspondingly, which is several times larger than for common silica glass (9.4 pm/K). Importantly, dλ/dT was almost independent of microresonator size, WGM polarization and structure; this is a practically crucial feature showing the robustness of the sensing devices of the proposed design.

Mechanical and thermal insulation performance of hollow glass microsphere (HGMS)/fumed silica/polyester microcomposite coating

Numerous insulating materials such as coatings have been developed and are commercially available. Hollow glass microspheres (HGMS) as well as fumed silica, despite their intrinsic properties, have received less attention in formulation of coatings. Here, we hypothesized the utilization of the fillers to evaluate and compare their effects on the insulating efficiency, mechanical response and surface adhesion of a class of micro-composites functioning as thin coatings. Polyester-based composite coatings were prepared using 0–30 wt% of HGMS and 0–12 wt% of fumed silica. The results confirmed the positive influence of the HGMS and fumed silica on the insulating performance of the fabricated coatings exhibiting around 20 % improvement compared to the pure polyester. It was shown that elastic response, impact resistance and the coatings/substrate strength are sensitive to the presence of fillers and are governed by the fillers type and loading as well as the interfacial restricted region and morphology of the composites.

Influence of the grinding wheel recipe on the cutting force components during grinding

The issues of the components of a grinding wheel recipe, namely, abrasive grains, bonds and various fillers on the cutting forces during grinding are considered in the article. The following types of fillers were studied: fused alumina microspheres, which are a non-burning hollow filler, glass microspheres used as a hollow melting filler, and a burning filler in the form of crushed fruit pits. On the basis of the obtained experimental data, generalized statistical models of the dependence of the magnitude of cutting forces during grinding on the percentage of grains, bond and fillers were developed. From the analysis of the pair correlation coefficients of the models of the grinding force components, it was concluded that the percentage of grains, bond, glass microspheres have the strongest effect on the cutting force sand the effect of fused alumina microspheres and fruit pits is negligible. Based on the results obtained, conclusions are formulated in the form of practical recommendations for reducing cutting forces.

Microwave Properties of Carbon Magnetic Shell Structures, Based on Glass Microspheres, With a Coating Consisting of Ferromagnetic Compounds and Nanocarbon

Microwave Properties of Carbon Magnetic Shell Structures, Based on Glass Microspheres, With a Coating Consisting of Ferromagnetic Compounds and Nanocarbon

Road Marking Glass Microspheres Fabricated from Rice Husk Ash

In this work, it is reported a comparison between solid microspheres produced from glass having conventional industrial sand (IS) and glasses made with rice husk ashes (RHA) as a source of silica. The same composition was used to fabricate both glasses. The focused was the production of glass microspheres for road horizontal marking, which would attend the type classification called Premix. The microspheres were obtained by the horizontal flame method. The results showed that characteristics such as production yield, morphology, granulometry and, mainly, retroreflectivity measurements are not altered when rice husk ash is present in the glass composition, showing that this can be a sustainable alternative material for this important application.

Refractive index dispersion measurement in the short-wave infrared range using synthetic phase microscopy.

Refractive index is an optical property explored in the light scattering measurement of micro- and nano-particles as well as in label-free imaging of cells and tissues. Because the refractive index value is a major input to the characterization and quantification of the analyzed specimens, various methods have been developed targeting at different sample types. In this paper, we demonstrate a technique for the refractive index measurement of homogeneous microspheres and liquids in the short-wave infrared (SWIR) range. We use synthetic phase microscopy (SPM), which records a scattering-corrected projection of the 3D refractive index distribution, in combination with a least-squares fitting to a theoretical model of a sphere. Using the method, we determine the refractive index dispersion of two polymer microspheres (polymethyl methacrylate and polystyrene), two glass microspheres (silica and soda lime), and three microscopy mounting media (glycerol, FluorSave, and Eukitt) in the SWIR range of 1100-1650 nm.

Investigation of mechanical characterization of hybrid sandwich composites with syntactic foam core for structural applications

In this work, mechanical performance on sandwich composites consisting of syntactic foam filled with hollow glass microsphere in an epoxy resin matrix as the core material and hybrid kenaf/glass fibers face-sheet based composites panel is studied. The main purpose of this work is to design a suitable lightweight composite panel material for structural application. Four different sequences of face-sheet reinforcement (e.g., kenaf-kenaf; glass-glass; glass-kenaf, and kenaf-glass) were adopted. In this study, the mechanical properties and failure modes are carefully investigated. The sandwich composites were characterized by compressive, tensile, and flexural properties. The results showed that compressive strength was highest at the “kenaf-glass” face-sheets, tensile strength was highest at “glass-glass” face-sheets, and flexural at “glass-glass” face-sheets with 52.1%, 67.6%, and 74.4% increase to “kenaf-kenaf” face-sheets, respectively. The tensile strength and modulus values with the specific strengths and modulus values showed that the mechanical properties of the sandwich composites can be influenced by hybridizing the face-sheet laminates of the composite. This shows that kenaf fiber has limited strength when used as reinforcement alone but gave an excellent performance when combined with glass fiber.

Light scattering in a three-phase photosensitive system via Monte Carlo approach.

Digital light processing (DLP)-based additive manufacturing has emerged as a powerful technique for fabricating structures from filled resin systems, in which the light scattering behavior is critical to the dimensional fidelity of the cured part. Recently created low density filled resins that incorporate hollow microspheres introduce a third optically active phase, producing yet more complex scattering and cure behaviours that existing empirical relationships cannot predict. This study simulates light scattering in these systems via Mie theory and a novel Monte Carlo model, providing insight into the relationship between filler volume fraction and cured dimensions, and proposes an inversion parameter for predicting film dimensions. Cured resin geometry dimensions such as cured depth (CD) and cured width (CW) are predicted using the developed model for 10, 30, and 50 vol% hollow glass microsphere filled resin systems. In contrast to standard two-phase models, our three-phase model predicts a positive relationship between cured depths and half-widths and the filler volume fraction, consistent with experimental data. By elucidating the intricacies of light scattering in three-phase systems, this work provides valuable insights for advancing DLP-based additive manufacturing and designing filled resin formulations to achieve the desired cured dimensions.

Lightweight shear stiffening gel with enhanced mechanical and thermal-insulating performance for advanced fire suit

A lightweight and thermal-insulating shear stiffening gel (LT-SSG) with anti-impact was developed via introducing hollow glass microspheres BR20 into shear stiffening gel (SSG). It was lightweight enough to be placed on a leaf. LT-SSG showed the ability to resist impact. Finally, a multifunctional Kevlar safeguarding suit (MKSS) with flame retardant property was fabricated. It exhibited good adiabatic effect which could isolate heat at high temperatures and prevent heat loss at low temperatures. • LT-SSG with lightweight, heat-insulation and anti-impact properties was prepared. • LT-SSG showed enhanced protective effect due to the existence of BR20 particles. • A multifunctional Kevlar safeguarding suit (MKSS) was assembled. • MKSS was capable to resist fire combustion and displayed good adiabatic effect. • MKSS effectively prevented the heat loss from humans in cold environment. Herein, a lightweight and thermal-insulating shear stiffening gel (LT-SSG) with anti-impact was prepared by introducing insulating glass microspheres BR20 into SSG. The density of LT-SSG was 48.97% lower than that of SSG. Meantime, LT-SSG showed excellent energy absorption effect. The remained impact force of LT-SSG was only 0.23 kN compared with 0.41 kN of SSG when impacted from 20 cm. Moreover, LT-SSG with good thermal insulation performance could effectively isolate surrounding temperature to 42.6 ℃ at 80 ℃ and block external cold temperature to protect the heat loss from human body. While SSG as well as the breakage of BR20 particles absorbed and dissipated much impact energy, proving its excellent protective properties. Finally, a multifunctional Kevlar safeguarding suit (MKSS) was developed. It showed the ability to resist low-speed drop hammer and high-speed ballistic impact. To this end, the reported LT-SSG showed promising application in fire suit and body armors.