HomeHypertensionAhead of PrintDisconnected Cardiac Autonomic Nerves in Genetic Ganglionic Acetylcholine Receptor Alpha-3 Subunit Deficiency No AccessResearch ArticleRequest AccessAboutView PDFSections ToolsAdd to favoritesDownload citationsTrack citationsPermissions ShareShare onFacebookTwitterLinked InMendeleyReddit Jump toNo AccessResearch ArticleRequest AccessDisconnected Cardiac Autonomic Nerves in Genetic Ganglionic Acetylcholine Receptor Alpha-3 Subunit Deficiency Karsten Heusser, Florian Erger, Ulrich Ebner, Barbara Namer, Graeme Eisenhofer, Carl-Albrecht Haensch, Henning Weis, Matthias Schmidt, Alexander Drzezga, Jens Tank, Christian Netzer and Jens Jordan Karsten HeusserKarsten Heusser https://orcid.org/0000-0002-2571-5585 Institute of Aerospace Medicine, German Aerospace Center (DLR), Cologne, Germany (K.H., H.W., J.T., J.J.). *K. Heusser and F. Erger contributed equally. Search for more papers by this author , Florian ErgerFlorian Erger https://orcid.org/0000-0002-2768-1702 Institute of Human Genetics, Medical Faculty, University of Cologne, Germany (F.E., C.N.). *K. Heusser and F. Erger contributed equally. Search for more papers by this author , Ulrich EbnerUlrich Ebner https://orcid.org/0009-0002-4648-8497 Internal Medicine Practice, Regensburg, Germany (U.E.). Search for more papers by this author , Barbara NamerBarbara Namer https://orcid.org/0000-0001-7500-2842 Institute of Physiology and Pathophysiology, Friedrich Alexander University Erlangen-Nuremberg, Germany (B.N.). Research Group Neuroscience, Interdisciplinary Centre for Clinical Research within the Faculty of Medicine at the RWTH Aachen University, Germany (B.N.). Department for Physiology, Faculty of Medicine at the RWTH Aachen University, Germany (B.N.). Search for more papers by this author , Graeme EisenhoferGraeme Eisenhofer Institute of Clinical Chemistry and Laboratory Medicine, University Hospital Carl Gustav Carus, Medical Faculty, Technical University Dresden, Germany. (G.E.) University Hospital Carl Gustav Carus, Medical Faculty Carl Gustav Carus and Department of Medicine III, University Hospital Carl Gustav Carus, Medical Faculty, Technical University Dresden, Germany. (G.E.) Search for more papers by this author , Carl-Albrecht HaenschCarl-Albrecht Haensch https://orcid.org/0000-0001-6479-0265 Kliniken Maria Hilf Mönchengladbach, Autonomic Laboratory, Department of Neurology, Faculty of Health, University of Witten/Herdecke, Mönchengladbach, Germany (C.-A.H.). Search for more papers by this author , Henning WeisHenning Weis https://orcid.org/0000-0001-8638-3281 Institute of Aerospace Medicine, German Aerospace Center (DLR), Cologne, Germany (K.H., H.W., J.T., J.J.). Department of Nuclear Medicine, Faculty of Medicine and University Hospital Cologne, University of Cologne, Germany (H.W., M.S., A.D.). Search for more papers by this author , Matthias SchmidtMatthias Schmidt https://orcid.org/0000-0002-7519-8897 Department of Nuclear Medicine, Faculty of Medicine and University Hospital Cologne, University of Cologne, Germany (H.W., M.S., A.D.). Search for more papers by this author , Alexander DrzezgaAlexander Drzezga Department of Nuclear Medicine, Faculty of Medicine and University Hospital Cologne, University of Cologne, Germany (H.W., M.S., A.D.). Search for more papers by this author , Jens TankJens Tank https://orcid.org/0000-0002-5672-1187 Institute of Aerospace Medicine, German Aerospace Center (DLR), Cologne, Germany (K.H., H.W., J.T., J.J.). Search for more papers by this author , Christian NetzerChristian Netzer Institute of Human Genetics, Medical Faculty, University of Cologne, Germany (F.E., C.N.). †C. Netzer and J. Jordan contributed equally. Search for more papers by this author and Jens JordanJens Jordan Correspondence to: Jens Jordan, Institute for Aerospace Medicine, Linder Hoehe, 51147 Cologne, Germany. Email E-mail Address: [email protected] https://orcid.org/0000-0003-4518-0706 Institute of Aerospace Medicine, German Aerospace Center (DLR), Cologne, Germany (K.H., H.W., J.T., J.J.). †C. Netzer and J. Jordan contributed equally. Search for more papers by this author Originally published10 May 2023https://doi.org/10.1161/HYPERTENSIONAHA.123.21172Hypertension. 2023;0Footnotes*K. Heusser and F. Erger contributed equally.†C. Netzer and J. Jordan contributed equally.For Sources of Funding and Disclosures, see page XXX.Correspondence to: Jens Jordan, Institute for Aerospace Medicine, Linder Hoehe, 51147 Cologne, Germany. Email jens.[email protected]de Previous Back to top Next FiguresReferencesRelatedDetails Advertisement Article InformationMetrics © 2023 American Heart Association, Inc.https://doi.org/10.1161/HYPERTENSIONAHA.123.21172PMID: 37161764 Originally publishedMay 10, 2023 KeywordsCHRNA3autonomic failureganglionic acetylcholine receptorsympathetic nervous systemPDF download Advertisement SubjectsAutonomic Nervous SystemGeneticsMechanismsNuclear Cardiology and PETPathophysiology