The diaphragm plays a crucial role in distributing seismic forces within buildings during earthquakes, affecting both regular and irregular structures differently. This study investigates the seismic behavior of diaphragms in various building geometries resembling the letters I, T, L, and O, focusing on their influence on structural performance and reinforcement requirements. Using analytical methods, diaphragm seismic forces, slab shear stresses, and internal forces were calculated for a sample of buildings with different geometrical irregularities. The study reveals significant differences in diaphragm earthquake forces between regular and irregular buildings, with irregular geometries exhibiting distinct patterns of shear stress distribution. Particularly, the building with an L-shaped plan and concentrated stress points showed the highest maximum shear stresses in both orthogonal directions. Analysis of internal forces—axial, shear, and moment—highlighted varying reinforcement needs among the studied buildings. While axial and shear forces necessitated minimal additional reinforcement across all structures, moment forces indicated substantial reinforcement requirements, particularly in the L-shaped building. These findings underscore the importance of tailored diaphragm design strategies for buildings with irregular geometries to mitigate potential structural vulnerabilities during seismic events. The study contributes insights into optimizing diaphragm design practices and emphasizes the need for further research in this critical area of structural engineering.